Capnocytophaga bacteria live in the mouths of cats and dogs without making them sick. Rarely, people can be infected with these germs after a bite or close contact with animals.
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Capnocytophaga Infection
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Chinook Dog
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Capnocytophaga Infection
Many kinds of bacteria (germs) called Capnocytophaga live in the mouths of dogs and cats. These germs do not make dogs or cats sick.
Rarely, Capnocytophaga germs can spread to people through bites, scratches, or close contact from a dog or cat and may cause illness, including sepsis. Most people who have contact with a dog or cat do not become sick. People with a weakened immune systems who have difficulty fighting off infections (for example, people with cancer or those taking certain medications such as steroids) are at greater risk of becoming ill.
Source: Centers for Disease Control and Prevention (CDC)
Additional Materials (3)
Man Loses Limbs After Contracting Rare Blood Infection From Dog Saliva | TIME
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Capnocytophaga canimorsus presentation
Video by Courtney Todd/YouTube
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0:53
Man Loses Limbs After Contracting Rare Blood Infection From Dog Saliva | TIME
TIME/YouTube
13:26
Capnocytophaga canimorsus presentation
Courtney Todd/YouTube
Three, Dog, Adorable
igorovsyannykov/Pixabay
Transmission
Dog licking owner
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Dog licking owner
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How Do People Get Infected with Capnocytophaga?
Many Capnocytophaga germs are normal bacteria commonly found in the mouths of people, dogs, and cats. These germs sometimes cause opportunistic infections, which means under the right conditions they can cause an infection, such as in a person with a weakened immune system.
People with weakened immune systems include those who:
Drink alcohol excessively
Have had their spleens removed
Have HIV infection or cancer
People with these conditions should speak with their doctors about how to safely interact with cats and dogs.
The Capnocytophaga germs that are common in dogs and cats can be spread to people through a bite or after close contact with dogs or cats. Infections are more often linked to dog bites or dog contact.
See the Preventing Dog Bites page for information on how to prevent dog bites and what to do if you are bitten, regardless of your health status.
Other Capnocytophaga germs can also be found in human mouths and can cause illness in some people who have the bacteria in their own mouth. People who have weak immune systems get this type of infection more often than healthy people.
Most reported infections occur in tissues connected to the mouth and throat, including:
Periodontal (gum) disease
Respiratory tract infections (infections of the mouth, nose, throat, and lungs)
Eye infections
In both types of infections—those that spread from animals or from oneself—the bacteria can enter the blood stream, which can lead to infection in various parts of the body. Infection can also cause the following:
Septicemia (blood infection)
Endocarditis (inflammation of the lining of the heart)
Abscesses (collections of pus in the tissue that cause redness and swelling) in various body tissues
Inflammation of the eyes, face, lymph nodes, or brain membranes
Most contact with dogs and cats does not lead to a Capnocytophaga infection or any illness, even after a bite. But, you should take precautions if you have contact with animals, especially if you have a condition that puts you at higher risk of infection.
Source: Centers for Disease Control and Prevention (CDC)
Additional Materials (1)
Capnocytophaga canimorsus gram stain
Capnocytophaga canimorsus gram stain. Thin Gram-negative rod, often fusiform shaped. May show pleomorphism in older cultures.
Image by Suryabrata Banerjee (microregistrar.com)/Wikimedia
People who are infected with Capnocytophaga can have a range of signs and symptoms such as:
Blisters around the bite wound within hours of the bite
Redness, swelling, draining pus, or pain at the bite wound
Fever
Diarrhea and/or stomach pain
Vomiting
Headache and/or confusion
Muscle or joint pain
After being bitten, most people who become ill will show symptoms within 3 to 5 days, but this can range anywhere from 1 to 14 days.
Most Capnocytophaga infections usually occur with dog or cat bites. But some people who develop a Capnocytophaga infection have not been bitten. People may be infected after close contact with a dog or cat, especially after contact with the animal’s saliva (spit).
Capnocytophaga infection can cause serious complications, including heart attack, kidney failure, and gangrene. Some people may need to have fingers, toes, or even limbs amputated because of complications from severe infection.
About 3 in 10 people who develop a severe infection die. Some infections can progress very quickly, result in sepsis, and lead to death within 24 to 72 hours after symptoms start.
If you have been bitten by a dog or cat, wash the bite area right away with soap and water, and call your doctor, even if you don’t feel sick. This is because dog and cat bites can pose a risk for rabies, as well as Capnocytophaga.
Source: Centers for Disease Control and Prevention (CDC)
Additional Materials (1)
Capnocytophaga canimorsus gram stain
Capnocytophaga canimorsus gram stain. Thin Gram-negative rod, often fusiform shaped. May show pleomorphism in older cultures.
Image by Suryabrata Banerjee (microregistrar.com)/Wikimedia
The most common test for the human immunodeficiency virus (HIV) detects antibodies produced by the immune system that attack foreign particles like HIV. These antibodies are identifiable because they are tailor-made to match specific features of the virus. The human immunodeficiency virus (HIV) enters the body through sexual transmission, blood transfusion with infected blood, or, in the case of drug addicts, a shared needle contaminated by the blood of another user. HIV antibodies can be detected between 3-8 weeks after exposure to the virus.
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Risk of Capnocytophaga Infection
People with certain health conditions are at greater risk of infection, but anyone could become sick from Capnocytophaga bacteria.
You may have a higher risk of infection if you:
Use alcohol excessively
Do not have a spleen (asplenic)
Have an immuno-compromising conditions, including but not limited to:
Cancer
Diabetes
HIV infection
Are taking drugs that are toxic to cells (such as chemotherapy)
Most Capnocytophaga infections occur in adults over 40 years of age. However, cases have also been diagnosed in young children.
Capnocytophaga germs can cause serious illness in pregnant women and their unborn babies. Infection during the last few weeks of pregnancy can lead to inflammation of the membranes that surround the baby in the womb, a condition known as chorioamnionitis. In the newborn, it can also cause low birth weight, and it can lead to serious infection of the bloodstream or body tissues, known as sepsis.
If you have any of these conditions and have contact with dogs or cats, see the Prevention and Pets pages for more information. If you are bitten by a dog or cat, call your doctor immediately and describe your animal contact.
Source: Centers for Disease Control and Prevention (CDC)
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HIV Virus Replication Cycle
This infographic illustrates the HIV replication cycle, which begins when HIV fuses with the surface of the host cell. A capsid containing the virus’s genome and proteins then enters the cell. The shell of the capsid disintegrates and the HIV protein called reverse transcriptase transcribes the viral RNA into DNA. The viral DNA is transported across the nucleus, where the HIV protein integrase integrates the HIV DNA into the host’s DNA. The host’s normal transcription machinery transcribes HIV DNA into multiple copies of new HIV RNA. Some of this RNA becomes the genome of a new virus, while the cell uses other copies of the RNA to make new HIV proteins. The new viral RNA and HIV proteins move to the surface of the cell, where a new, immature HIV forms. Finally, the virus is released from the cell, and the HIV protein called protease cleaves newly synthesized polyproteins to create a mature infectious virus. Credit: NIAID
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What is HIV?
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HIV Virus
Creative artwork featuring colorized 3D prints of HIV virus particles. The virus surface of the prints (red) is covered with proteins (dark blue) that enable the virus to enter and infect human cells, and additional proteins (teal spheres) that disguise the virus from the immune system. A colorized transmission electron micrograph (TEM) of HIV virus particles (red) budding and replicating from an H9 T cell (blue) appears in the background. The virus particles in the TEM are in various stages of maturity, which accounts for differences in shape. Note: Creative layout is not to scale, including proteins on the 3D prints. Credit: NIAID
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HIV Virus Replication Cycle
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What is HIV?
HIV.GOV
Ways HIV is Not Transmitted
Ways HIV is Not Transmitted
HIV Virus
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Treatment
Antibiotics
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Antibiotics
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Treatment of Capnocytophaga Infection
Capnocytophaga infection can be treated with prescription medicine called antibiotics. Antibiotics kill bacterial germs like Capnocytophaga. It is important to call your doctor if you have been bitten by a dog or cat or believe that you might be infected with Capnocytophaga germs.
Different kinds of antibiotics can be used to treat Capnocytophaga infection. You may need to take more than one antibiotic to help you get better.
Source: Centers for Disease Control and Prevention (CDC)
Prevention
Animal bites Dog bite
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Animal bites Dog bite
Dog bite
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Prevention of Capnocytophaga Infection
Learn how to prevent dog bites and what to do if you are bitten by a dog or cat. If you are at a higher risk of infection with Capnocytophaga germs, it is important to seek medical care promptly.
If you start having symptoms within 14 days of being bitten, get medical care immediately. Tell your health care provider that you were recently bitten by an animal.
About 3 in 10 people (30%) who develop serious infections with Capnocytophaga germs die. Some infections can lead to death within 24 to 72 hours after symptoms start.
If you have been bitten by a dog or cat, wash the bite area right away with soap and water, and call your doctor, even if you don’t feel sick. This is because dog and cat bites can pose a risk for rabies, as well as Capnocytophaga.
People may be infected after close contact with a dog or cat without being bitten. If you are at higher risk of infection, speak with your doctor about how to protect yourself when you have contact with pets. Also, see the Pets page for information about safer contact with pets.
Source: Centers for Disease Control and Prevention (CDC)
Additional Materials (5)
Adhesive bandage on a hand following a dog bite, Singapore - 20121225
An adhesive bandage on an hand following a bite by a Shiba Inu in Singapore.
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Animal Bites Dog bite
Three days old dog bite
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Cat-scratch-disease
An enlarged lymph node in the armpit region of a person with cat-scratch disease, and wounds from a cat scratch on the hand.
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Cat
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Cat scratch disease new photo for diagnosis
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Cat Scratch Disease (Bartonella henselae Infection)
Cat scratch disease facts*
What is cat scratch disease? What are cat scratch disease symptoms and signs?
How do cats transmit Bartonella henselae to people?
What are serious but rare complications of cat scratch disease?
What is the treatment for cat scratch disease?
Is it possible to prevent cat scratch disease?
Where can people find more information about cat scratch disease?
CAT SCRATCH DISEASE (BARTONELLA HENSELAE INFECTION) CENTER
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Cat scratch disease facts*
What is cat scratch disease? What are cat scratch disease symptoms and signs?
How do cats transmit Bartonella henselae to people?
What are serious but rare complications of cat scratch disease?
What is the treatment for cat scratch disease?
Is it possible to prevent cat scratch disease?
Where can people find more information about cat scratch disease?
Cat scratch disease facts*
Cat scratch disease facts by John P. Cunha, DO, FACOEP
Cat scratch disease (CSD) is a bacterial disease caused by Bartonella henselae.
It is often caused by a bite or scratch from a cat. Kittens are more likely to pass on the bacteria. Cats who carry B. henselae do not show any signs of illness, so you cannot tell which cats could spread the disease to you.
Symptoms and signs of cat scratch disease include a bump or blister at the site of the scratch followed by
swollen lymph nodes (especially around the head, neck, and arms),
fever,
headache,
fatigue,
malaise,
sore throat,
weight loss, and
loss of appetite.
People with suppressed immune systems, such as people undergoing chemotherapy, organ transplant patients, and people with HIV/AIDS, are more likely to have complications of CSD.
Diagnosis of cat scratch disease is made by a history of a wound caused by a cat, physical exam showing signs of lymph node swelling, indirect fluorescence assay (IFA), and enzyme-linked immunoassay (ELISA) blood testing, and possibly lymph node biopsy.
Treatment for cat scratch disease includes antibiotics such as azithromycin (Zithromax), clarithromycin (Biaxin), rifampin (Rifadin), trimethoprim-sulfamethoxazole (Bactrim), and ciprofloxacin (Cipro).
To reduce your risk of getting CSD, avoid rough play with cats and kittens, wash cat bites and scratches thoroughly, don't allow cats to lick any open wounds you have, and contact your physician if you develop any symptoms or signs following a cat bite or scratch.
What is cat scratch disease?
Cat-scratch disease (CSD) is a bacterial infection spread by cats. The disease spreads when an infected cat licks a person's open wound, or bites or scratches a person hard enough to break the surface of the skin. About three to 14 days after the skin is broken, a mild infection can occur at the site of the scratch or bite. The infected area may appear swollen and red with round, raised lesions and can have pus. The infection can feel warm or painful. A person with CSD may also have a fever, headache, poor appetite, and exhaustion. Later, the person's lymph nodes closest to the original scratch or bite can become swollen, tender, or painful.
Wash cat bites and scratches well with soap and running water. Do not allow cats to lick your wounds. Contact your doctor if you develop any symptoms of cat-scratch disease or infection.
CSD is caused by a bacterium called Bartonella henselae. About 40% of cats carry B. henselae at some time in their lives, although most cats with this infection show NO signs of illness. Kittens younger than 1 year are more likely to have B. henselae infection and to spread the germ to people. Kittens are also more likely to scratch and bite while they play and learn how to attack prey.
Image by MORINGA2050/Wikimedia
Adhesive bandage on a hand following a dog bite, Singapore - 20121225
Jacklee/Wikimedia
Animal Bites Dog bite
Nicor
Cat-scratch-disease
CDC/Wikimedia
Cat
thefairypath/Pixabay
Cat scratch disease new photo for diagnosis
MORINGA2050/Wikimedia
Infection in Pets
Corynebacterium diphtheriae
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Corynebacterium diphtheriae
Corynebacterium diphtheriae
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Pets and Capnocytophaga Germs
Most dogs and many cats have Capnocytophaga and other germs in their mouths (oral flora). These germs do not make the animals sick. Animals can be tested to see if they have Capnocytophaga germs, but a negative result may not mean the animal will always be negative – and the same is true for a positive result. Although animals could be given medicine to get rid of the germs in the short term, they will likely get them again after contact with other animals.
Having pets like dogs and cats has many benefits. Most contact with dogs and cats does not lead to a Capnocytophaga infection or any illness, even after a bite. But, you should take precautions if you have contact with animals, especially if you have a condition that puts you at higher risk of infection.
Source: Centers for Disease Control and Prevention (CDC)
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Capnocytophaga Infection
Capnocytophaga bacteria live in the mouths of cats and dogs without making them sick. Rarely, people can be infected with these germs after a bite or close contact with animals.