Erythema elevatum diutinum (EED) is type of small blood vessel inflammation that affects the skin. Symptoms include red, purple, brown or yellow bumps on different sizes that grow on or just below the skin. These growths are located mainly on the elbows, knees, ankles, hands, and fingers. People with EED may also have joint pain, but few other symptoms. EED symptoms begin in adulthood and can last for many years. Many cases get better on their own, but this may take many years. The cause of EED is unknown. Diagnosis is made based on the symptoms and a skin biopsy to look at the skin growths. Treatment includes antibiotics and other medications.

• Red-violet to red-brown skin bumps (papules, nodules)
• Red, itchy patches of skin (plaques)
• Pain or burning
• Joint pain (arthralgia)

Treatment of erythema elevatum diutinum is based on managing the symptoms. Medications such as antibiotics, non-steroidal anti-inflammatories, and antimicrobials may be used. The skin growths may recur if medication is stopped. In some cases, surgery may be necessary to remove the skin growths.