Throat cancer is a type of head and neck cancer. Throat cancer has different names, depending on which part of the throat is affected. The different parts of your throat are called the oropharynx, the hypopharynx, the nasopharynx, and the larynx, or voice box.

The main risk factors for throat cancer are using tobacco heavy drinking. Certain types of throat cancer also have other risk factors. For example, having HPV is a risk factor for oropharyngeal cancer.

Symptoms of throat cancer may include

• A sore throat that does not go away
• A lump in the neck
• Pain or ringing in the ears
• Trouble swallowing
• Ear pain

To diagnose throat cancers, doctors may do a physical exam and history, imaging tests, and a biopsy. You may also need other tests, depending on the type of cancer. Treatments include surgery, radiation therapy, and chemotherapy. Treatment for some types of throat cancer may also include targeted therapy. Targeted therapy uses substances that attack cancer cells without harming normal cells.

Your throat is a tube that carries food to your esophagus and air to your windpipe and larynx. The technical name for your throat is the pharynx.

Throat problems are common. You've probably had a sore throat. The cause is usually a viral infection, but other causes include allergies, infection with strep bacteria or the leaking of stomach acids back up into the esophagus, called GERD.

Other problems that affect the throat include

• Tonsillitis - inflammation of the tonsils
• Cancer
• Croup - inflammation, usually in small children, which causes a barking cough
• Laryngitis - swelling of the voice box, which can cause a hoarse voice or loss of voice

Most throat problems are minor and go away on their own. Treatments, when needed, depend on the problem.

Adenoids are a patch of tissue that is high up in the throat, just behind the nose. They, along with the tonsils, are part of the lymphatic system. The lymphatic system clears away infection and keeps body fluids in balance. The adenoids and tonsils work by trapping germs coming in through the mouth and nose.

Adenoids usually start to shrink after about age 5. By the teenage years, they are almost completely gone. By then, the body has other ways to fight germs.

What are enlarged adenoids?

Enlarged adenoids are adenoids that are swollen. It is a common problem in children.

Croup is an inflammation of the vocal cords (larynx) and windpipe (trachea). It causes difficulty breathing, a barking cough, and a hoarse voice. The cause is usually a virus, often parainfluenza virus. Other causes include allergies and reflux.

Croup often starts out like a cold. But then the vocal cords and windpipe become swollen, causing the hoarseness and the cough. There may also be a fever and high-pitched noisy sounds when breathing. The symptoms are usually worse at night, and last for about three to five days.Children between the ages of 6 months and 3 years have the highest risk of getting croup. They may also have more severe symptoms. Croup is more common in the fall and winter.

Most cases of viral croup are mild and can be treated at home. Rarely, croup can become serious and interfere with your child's breathing. If you are worried about your child's breathing, call your health care provider right away.

Your mouth is one of the most important parts of your body. It has many different functions. It allows you to

• Take in food and drink
• Breathe in air
• Start digestion, with your teeth chewing the food you eat and your salivary glands releasing saliva to help break down the food
• Speak and sing
• Show emotion, by smiling or pouting

Any problem that affects your mouth can make it hard to eat, drink, or even smile. Some common mouth problems include

• Cold sores - painful sores on the lips and around the mouth, caused by a virus
• Canker sores - painful sores in the mouth, caused by bacteria or viruses
• Thrush - a yeast infection that causes white patches in your mouth
• Leukoplakia - white patches of excess cell growth on the cheeks, gums or tongue, common in smokers
• Dry mouth - a lack of enough saliva, caused by some medicines and certain diseases
• Gum or tooth problems
• Bad breath

Treatment for mouth disorders varies, depending on the problem. If a mouth problem is caused by some other disease, treating that disease can help. It is also important to keep your mouth clean and healthy by brushing, flossing, and not using tobacco.

Your throat is a tube that carries food to your esophagus and air to your windpipe and larynx (also called the voice box). The technical name for the throat is pharynx.

You can have a sore throat for many reasons. Often, colds and flu cause sore throats. Other causes can include:

• Allergies
• Mononucleosis
• Smoking
• Strep throat
• Tonsillitis

Treatment depends on the cause. Sucking on lozenges, drinking lots of liquids, and gargling may ease the pain. Over-the-counter pain relievers can also help, but children should not take aspirin.

Many disorders can affect our ability to speak and communicate. They range from saying sounds incorrectly to being completely unable to speak or understand speech. Causes include

• Hearing disorders and deafness
• Voice problems, such as dysphonia or those caused by cleft lip or palate
• Speech problems like stuttering
• Developmental disabilities
• Learning disorders
• Autism spectrum disorder
• Brain injury
• Stroke

Some speech and communication problems may be genetic. Often, no one knows the causes. By first grade, about 5 percent of children have noticeable speech disorders. Speech and language therapy can help.

If you have a swallowing disorder, you may have difficulty or pain when swallowing. Some people cannot swallow at all. Others may have trouble swallowing liquids, foods, or saliva. This makes it hard to eat. Often, it can be difficult to take in enough calories and fluids to nourish your body.

Anyone can have a swallowing disorder, but it is more likely in the elderly. It often happens because of other conditions, including

• Nervous system disorders, such as Parkinson's disease and cerebral palsy
• Problems with your esophagus, including GERD (gastroesophageal reflux disease)
• Stroke
• Head or spinal cord injury
• Cancer of the head, neck, or esophagus

Medicines can help some people, while others may need surgery. Swallowing treatment with a speech-language pathologist can help. You may find it helpful to change your diet or hold your head or neck in a certain way when you eat. In very serious cases, people may need feeding tubes.

What is tonsillitis?

Tonsillitis is an inflammation (swelling) of the tonsils. Sometimes along with tonsillitis, the adenoids are also swollen.

What are tonsils?

Tonsils are lumps of tissue at the back of the throat. There are two of them, one on each side. Along with the adenoids, tonsils are part of the lymphatic system. The lymphatic system clears away infection and keeps body fluids in balance. Tonsils and adenoids work by trapping the germs coming in through the mouth and nose.

Voice is the sound made by air passing from your lungs through your larynx, or voice box. In your larynx are your vocal cords, two bands of muscle that vibrate to make sound. For most of us, our voices play a big part in who we are, what we do, and how we communicate. Like fingerprints, each person's voice is unique.

Many things we do can injure our vocal cords. Talking too much, screaming, constantly clearing your throat, or smoking can make you hoarse. They can also lead to problems such as nodules, polyps, and sores on the vocal cords. Other causes of voice disorders include infections, upward movement of stomach acids into the throat, growths due to a virus, cancer, and diseases that paralyze the vocal cords.

Signs that your voice isn't healthy include

• Your voice has become hoarse or raspy
• You've lost the ability to hit some high notes when singing
• Your voice suddenly sounds deeper
• Your throat often feels raw, achy, or strained
• It's become an effort to talk

Treatment for voice disorders varies depending on the cause. Most voice problems can be successfully treated when diagnosed early.

Oral cancer can form in any part of the mouth. Most oral cancers begin in the flat cells that cover the surfaces of your mouth, tongue, and lips. Anyone can get oral cancer, but the risk is higher if you are male, use tobacco, drink lots of alcohol, have HPV, or have a history of head or neck cancer. Frequent sun exposure is also a risk factor for lip cancer.

Symptoms of oral cancer include

• White or red patches in your mouth
• A mouth sore that won't heal
• Bleeding in your mouth
• Loose teeth
• Problems or pain with swallowing
• A lump in your neck
• An earache

Tests to diagnose oral cancer include a physical exam, endoscopy, biopsy, and imaging tests. Oral cancer treatments may include surgery, radiation therapy, and chemotherapy. Some patients have a combination of treatments.

Head and neck cancer includes cancers of the mouth, nose, sinuses, salivary glands, throat, and lymph nodes in the neck. Most begin in the moist tissues that line the mouth, nose, and throat. Symptoms include:

• A lump or sore that does not heal
• A sore throat that does not go away
• Trouble swallowing
• A change or hoarseness in the voice

Head and neck cancers are twice as common in men. Using tobacco or alcohol increases your risk. In fact, around 75% of head and neck cancers are linked to tobacco use, including smoking and smokeless tobacco. Infection with HPV is a risk factor for some head and neck cancers.

To diagnose head and neck cancer, your doctor will do a physical exam and diagnostic tests. You will have a biopsy, where a sample of tissue is taken out and examined under a microscope. It is the only test that can tell for sure if you have cancer.

If found early, these cancers are often curable. Treatments may include surgery, radiation therapy, chemotherapy, or a combination. Treatments can affect eating, speaking or even breathing, so patients may need rehabilitation.

Cancer is a disease in which cells of the body grow out of control. Cancers of the head and neck include cancers that start in several places in the head and throat, not including brain cancers or cancers of the eye.

Head and Neck Cancer Regions

This illustration shows the location of the nasopharynx, uvula, palatine tonsils, oropharynx, base of tongue, posterior pharyngeal wall, lingual tonsils, hypopharynx, soft palate, hard palate, anterior tongue, lips, floor of mouth, gum, salivary glands, and HPV-associated oropharyngeal sites.

Note: Salivary glands are located throughout the oral cavity. These are identified for illustrative purposes only. Not all sites, such as cheek, are included in this figure.

These cancers can start—

• In the sinuses (the spaces around the nose on the inside of the skull).
• Inside and behind the nose.
• In the mouth, including the tongue, the gums, and the roof of the mouth.
• In the back of the mouth and the throat (pharynx), which includes three sections called the nasopharynx, oropharynx, and hypopharynx.
• In the larynx (voice box).
• On the lips, although cancer on the lips is a type of skin cancer.
• In the glands that make saliva for the mouth, but those are relatively rare.

To lower your risk for head and neck cancers, don’t use tobacco products, limit the amount of alcohol you drink, and avoid indoor tanning.

What Are the Symptoms of Head and Neck Cancers?

In the mouth, cancer can cause—

• A white or red sore that does not heal on the gums, tongue, or lining of the mouth.
• Swelling in the jaw.
• Unusual bleeding or pain in the mouth.
• A lump or thickening.
• Problems with dentures.

At the back of the mouth (pharynx), cancer can cause—

• Trouble breathing or speaking.
• A lump or thickening.
• Trouble chewing or swallowing food.
• A feeling that something is caught in the throat.
• Pain in the throat that won’t go away.
• Pain or ringing in the ears or trouble hearing.

In the voice box (larynx), cancer can cause—

• Pain when swallowing.
• Ear pain.

In the sinuses and nasal cavity, cancer can cause—

• Blocked sinuses that don’t clear.
• Sinus infections that do not respond to treatment with antibiotics.
• Bleeding through the nose.
• Headaches.
• Pain and swelling around the eyes.
• Pain in the upper teeth.
• Problems with dentures.

What Causes Head and Neck Cancers?

Alcohol and tobacco are major risk factors for cancers of the head and neck. All tobacco products, including cigarettes, cigars, pipes, and smokeless tobacco (chewing tobacco, snuff, or a type of chewing tobacco called betel quid) are linked to head and neck cancer (except for salivary gland cancers). Drinking any type of alcohol, such as beer, wine, or liquor, also raises the risk of getting cancers of the mouth, throat, and voice box.

About 70% of cancers in the oropharynx (which includes the tonsils, soft palate, and base of the tongue) are linked to human papillomavirus (HPV), a common sexually transmitted virus.

Ultraviolet (UV) light exposure, such as exposure to the sun or artificial UV rays like tanning beds, is a major cause of cancer on the lips.

Occupational exposures, or being exposed to certain substances while on the job, can increase the risk of getting cancers in the nasopharynx. Working in the construction, textile, ceramic, logging, and food processing industries can cause people to be exposed to substances like wood dust, formaldehyde, asbestos, nickel, and other chemicals.

An infection with the Epstein-Barr virus, a cause of infectious mononucleosis and other illnesses, can raise the risk of cancers in the nose, behind the nose, and cancers of the salivary glands.

Radiation treatments to the head and neck can cause head and neck cancers.

About twice as many men as women get head and neck cancers. They are more likely to be diagnosed in people who are over 50 years of age.

How Can I Reduce My Risk for Head and Neck Cancers?

You can lower your risk of getting head and neck cancer in several ways—

• Don’t smoke. If you smoke, quit. Quitting smoking lowers the risk for cancer.
• Don’t use smokeless tobacco products.
• Limit the amount of alcohol you drink.
• Talk to your doctor about HPV vaccination. The HPV vaccine can prevent new infections with the types of HPV that most often cause oropharyngeal and other cancers. Vaccination is recommended only for people at certain ages.
• Use condoms and dental dams consistently and correctly during oral sex, which may help lower the chances of giving or getting HPV.
• Use lip balm that contains sunscreen, wear a wide-brimmed hat when outdoors, and avoid indoor tanning.
• Visit the dentist regularly. Checkups often can find head and neck cancers early, when they are easier to treat.

Cancers that are known collectively as head and neck cancers usually begin in the squamous cells that line the mucosal surfaces of the head and neck (for example, those inside the mouth, throat, and voice box). These cancers are referred to as squamous cell carcinomas of the head and neck. Head and neck cancers can also begin in the salivary glands, sinuses, or muscles or nerves in the head and neck, but these types of cancer are much less common than squamous cell carcinomas.

Cancers of the head and neck can form in the:

Oral cavity: Includes the lips, the front two-thirds of the tongue, the gums, the lining inside the cheeks and lips, the floor (bottom) of the mouth under the tongue, the hard palate (bony top of the mouth), and the small area of the gum behind the wisdom teeth.

Throat (pharynx): The pharynx is a hollow tube about 5 inches long that starts behind the nose and leads to the esophagus. It has three parts: the nasopharynx (the upper part of the pharynx, behind the nose); the oropharynx (the middle part of the pharynx, including the soft palate [the back of the mouth], the base of the tongue, and the tonsils); the hypopharynx (the lower part of the pharynx).

Voice box (larynx): The voice box is a short passageway formed by cartilage just below the pharynx in the neck. The voice box contains the vocal cords. It also has a small piece of tissue, called the epiglottis, which moves to cover the voice box to prevent food from entering the air passages.

Paranasal sinuses and nasal cavity: The paranasal sinuses are small hollow spaces in the bones of the head surrounding the nose. The nasal cavity is the hollow space inside the nose.

Salivary glands: The major salivary glands are in the floor of the mouth and near the jawbone. The salivary glands produce saliva. Minor salivary glands are located throughout the mucous membranes of the mouth and throat.

Image Caption : Head and neck cancer regions. Illustrates location of paranasal sinuses, nasal cavity, oral cavity, tongue, salivary glands, larynx, and pharynx (including the nasopharynx, oropharynx, and hypopharynx).

Cancers of the brain, the eye, the esophagus, the thyroid gland, and the skin of the head and neck are not usually classified as head and neck cancers.

If a squamous cell carcinoma of the head and neck is going to spread, it almost always does so locally and/or to the lymph nodes in the neck. Sometimes, cancerous squamous cells can be found in the lymph nodes of the upper neck when there is no evidence of cancer in other parts of the head and neck, possibly because the original primary tumor is too small. When this happens, the cancer is called metastatic squamous cell carcinoma with unknown (occult) primary.