What Is Vogt-Koyanagi-Harada Disease?
Source: Genetic and Rare Diseases (GARD) Information Center
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Vogt-Koyanagi-Harada Disease
VKH Disease; Vogt-Koyanagi-Harada Syndrome; VKH Syndrome; Uveomenigitic Syndrome
Vogt-Koyanagi-Harada disease (VKH disease) is a disease that affects several parts of the body, including the eyes, ears, nervous system, and skin. The signs and symptoms of VKH disease are caused by chronic inflammation of melanocytes. Learn more about VKH disease, its causes, symptoms and treatment.
Epidermis - Melanocyte
Image by Smart Servier website: Dermatology
Poliosis VKHS - The general diagnosis was a Vogt-Koyanagi-Harada syndrome.
Image by National Eye Institute/Wikimedia
Source: Genetic and Rare Diseases (GARD) Information Center
Unknown (película)
Image by Diseñadores publicitarios/Wikimedia
Source: Genetic and Rare Diseases (GARD) Information Center
This patient has loss of hair coloring in the left eyebrow and eyelashes (poliosis) with contiguous vitiligo.
Image by Herbert L. Fred, MD, Hendrik A. van Dijk/Wikimedia
The following list includes the most common signs and symptoms in people with Vogt-Koyanagi-Harada disease. These features may be different from person to person. Some people may have more symptoms than others and symptoms can range from mild to severe. This list does not include every symptom or feature that has been described in this condition.
The symptoms of Vogt-Koyanagi-Harada(VKH) disease occur in different phases. In the early phase, symptoms may include:
The uveitis phase occurs a few weeks after the early phase. In this phase, symptoms may include:
The convalescent phase usually occurs a few weeks to months after the uveitis phase. In this phase, symptoms may include:
The recurrent phase occurs in about half of the people with VKH disease. Symptoms may include:
Most people with VKH disease develop symptoms in both eyes. Vision and hearing problems can improve with treatment. The skin changes and hair loss may be permanent.
Source: Genetic and Rare Diseases (GARD) Information Center
Child's Eye Exam
Image by National Eye Institute, National Institutes of Health
Source: Genetic and Rare Diseases (GARD) Information Center
Treatment and Prognosis varies depending on the type of condition and the age of symptom onset.
Image by 4144132
Source: Genetic and Rare Diseases (GARD) Information Center
Prognosis Icon
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Source: Genetic and Rare Diseases (GARD) Information Center
Illustration of rare disease incidence
Image by mcmurryjulie/Pixabay
Source: Genetic and Rare Diseases (GARD) Information Center
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