Diabetes is a chronic disease in which your blood sugar levels are too high. Over time, having too much sugar in your blood can cause serious problems. There are three main types of diabetes: type 1, type 2, and gestational diabetes (diabetes while pregnant). Learn more about the three main types of diabetes and how to get tested.
Index finger with visible blood vessels and blood drop
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Diabetes
Insulin resistance (right side) contributes to high glucose levels in the blood.
Image by Scientific Animations, Inc.
Insulin resistance (right side) contributes to high glucose levels in the blood.
Mechanism of normal Blood Sugar absorption (Left) Vs. insulin resistance in Type 2 Diabetes (Right).
Image by Scientific Animations, Inc.
Diabetes
Diabetes is a disease in which your blood glucose, or blood sugar, levels are too high. Glucose comes from the foods you eat. Insulin is a hormone that helps the glucose get into your cells to give them energy. With type 1 diabetes, your body does not make insulin. With type 2 diabetes, the more common type, your body does not make or use insulin well. Without enough insulin, the glucose stays in your blood. You can also have prediabetes. This means that your blood sugar is higher than normal but not high enough to be called diabetes. Having prediabetes puts you at a higher risk of getting type 2 diabetes.
Over time, having too much glucose in your blood can cause serious problems. It can damage your eyes, kidneys, and nerves. Diabetes can also cause heart disease, stroke and even the need to remove a limb. Pregnant women can also get diabetes, called gestational diabetes.
Blood tests can show if you have diabetes. One type of test, the A1C, can also check on how you are managing your diabetes. Exercise, weight control and sticking to your meal plan can help control your diabetes. You should also monitor your blood glucose level and take medicine if prescribed.
Source: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Additional Materials (9)
Diabetes Mellitus TYPE 1,2,INSULIN,GLUCOSE
Video by davejaymanriquez/YouTube
Diabetes mellitus (type 1, type 2) & diabetic ketoacidosis (DKA)
Video by Osmosis/YouTube
Diabetes Mellitus and Type 2 Diabetes: Diagnosis & Management – Family Medicine | Lecturio
Diabetes Mellitus Pathophysiology & Nursing | Diabetes Nursing Lecture NCLEX | Type 1 & Type 2
RegisteredNurseRN/YouTube
3:59
Teen Diabetes Type 1& 2
Teen Kids News/YouTube
8:28
What is diabetes mellitus? | Endocrine system diseases | NCLEX-RN | Khan Academy
khanacademymedicine/YouTube
22:12
Diabetes Mellitus Pharmacology Medications | NCLEX Nursing Lecture on Management Made Easy
RegisteredNurseRN/YouTube
What Is Diabetes?
Importance of Insulin
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Importance of Insulin
Insulin is a potent hormone that has a powerful effect on many of the cells in your body. Your pancreas is always secreting a small amount of insulin, but rising glucose levels in the blood signal the pancreatic beta cells to produce and release greater amounts of insulin into the bloodstream. Without insulin, glucose would not be able to penetrate through plasma membranes and enter into cell interiors where it is used for energy or stored for future use. Insulin attaches to special sites on the cell membrane called insulin receptors. This attachment starts a long chain of events that lead to an increase in the number of glucose transporters, specialized protein molecules in the cell membrane. The glucose transporters form channels in the cell’s membrane that allow glucose to enter the cell through a process called facilitated diffusion. Insulin causes • Skeletal muscle fiber cells o to take up glucose from the blood, use it for energy, and store the rest as glycogen. Skeletal muscle is the major target for glucose, taking up about 50% of the amount available. o to take up amino acids and convert them to protein• Liver cells o to take up glucose from the blood and store it as glycogen to prepare for energy needs after food has been digested and absorbed o to inhibit production of the enzymes involved in breaking glycogen back down o to inhibit the conversion of fats and proteins into glucose • Fat cells o to take up glucose from the blood and make fat • Red blood cells o to take up glucose from the blood and use it for energy • The hypothalamus o to reduce your appetite The net result of all these insulin-mediated actions is the lowering of your glucose, or blood sugar, level.
Image by TheVisualMD
What Is Diabetes?
Diabetes is a chronic (long-lasting) health condition that affects how your body turns food into energy. With diabetes, your body either doesn’t make enough insulin or can’t use it as well as it should.
Most of the food you eat is broken down into sugar (also called glucose) and released into your bloodstream. When your blood sugar goes up, it signals your pancreas to release insulin. Insulin acts like a key to let the blood sugar into your body’s cells for use as energy.
If you have diabetes, your body either doesn’t make enough insulin or can’t use the insulin it makes as well as it should. When there isn’t enough insulin or cells stop responding to insulin, too much blood sugar stays in your bloodstream. Over time, that can cause serious health problems, such as heart disease, vision loss, and kidney disease.
There isn’t a cure yet for diabetes, but losing weight, eating healthy food, and being active can really help. Taking medicine as needed, getting diabetes self-management education and support, and keeping health care appointments can also reduce the impact of diabetes on your life.
Diabetes by the Numbers
34.2 million US adults have diabetes, and 1 in 5 of them don’t know they have it.
Diabetes is the seventh leading cause of death in the United States.
Diabetes is the No. 1 cause of kidney failure, lower-limb amputations, and adult blindness.
In the last 20 years, the number of adults diagnosed with diabetes has more than doubled.
Types of Diabetes
There are three main types of diabetes: type 1, type 2, and gestational diabetes (diabetes while pregnant).
Type 1 Diabetes
Type 1 diabetes is thought to be caused by an autoimmune reaction (the body attacks itself by mistake) that stops your body from making insulin. Approximately 5-10% of the people who have diabetes have type 1. Symptoms of type 1 diabetes often develop quickly. It’s usually diagnosed in children, teens, and young adults. If you have type 1 diabetes, you’ll need to take insulin every day to survive. Currently, no one knows how to prevent type 1 diabetes.
Type 2 Diabetes
With type 2 diabetes, your body doesn’t use insulin well and can’t keep blood sugar at normal levels. About 90-95% of people with diabetes have type 2. It develops over many years and is usually diagnosed in adults (but more and more in children, teens, and young adults). You may not notice any symptoms, so it’s important to get your blood sugar tested if you’re at risk. Type 2 diabetes can be prevented or delayed with healthy lifestyle changes, such as losing weight, eating healthy food, and being active.
Gestational Diabetes
Gestational diabetes develops in pregnant women who have never had diabetes. If you have gestational diabetes, your baby could be at higher risk for health problems. Gestational diabetes usually goes away after your baby is born but increases your risk for type 2 diabetes later in life. Your baby is more likely to have obesity as a child or teen, and more likely to develop type 2 diabetes later in life too.
Prediabetes
In the United States, 88 million adults—more than 1 in 3—have prediabetes. What’s more, more than 80% of them don’t know they have it. With prediabetes, blood sugar levels are higher than normal, but not high enough yet to be diagnosed as type 2 diabetes. Prediabetes raises your risk for type 2 diabetes, heart disease, and stroke. The good news is if you have prediabetes, a CDC-recognized lifestyle change program can help you take healthy steps to reverse it.
Source: Centers for Disease Control and Prevention (CDC)
Additional Materials (8)
Complications of diabetes mellitus
Diabetes and Small Vessel Disease : High levels of blood glucose damage the smallest vessels in your body, the capillaries, just as they do the larger vessels. One cause of this damage may be the high levels of advanced glycation end products (AGEs) that glucose creates inside capillary cells.
Image by TheVisualMD
Healthy Capillary Blood Vessel
Cross-section of Healthy Capillary Blood Vessel with Normal Glucose and Insulin Levels
Cross-Section of Damaged Capillary Blood Vessel with Very High Glucose and Insulin Levels
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Healthy Capillary Blood Vessel and and Damaged Capillary Blood Vessel Caused by High Levels of Blood Glucose
1) Healthy Capillary Blood Vessel - This image depicts a healthy capillary. Capillaries are the smallest blood vessels in your body. They can be so thin in diameter that blood cells have to bend in order to pass through. Capillaries are where the transfer of nutrients from the blood to cells, and the transfer of waste from cells to blood, takes place. In a healthy body, the blood vessels are smooth and elastic.
2) Cross-Section of Healthy Capillary Blood Vessel with Normal Glucose and Insulin Levels - This image depicts a healthy capillary. The body's cells depend on sugar in the blood, which is derived from carbohydrates, for food and energy. Allowing for the innumerable differences among individuals, the threshold for a normal blood sugar (glucose, pink) level in healthy people is 100 mg/dL; that is, 100 milligrams of glucose per deciliter of blood. Lower-than-normal levels characterize hypoglycemia and higher-than-normal levels characterize hyperglycemia. Without insulin (yellow), glucose is not able to enter cells to be used as fuel. Because of this, healthy insulin levels are a key factor in keeping blood glucose levels normal.
3) Cross-Section of Damaged Capillary Blood Vessel with Very High Glucose and Insulin Levels - This image depicts an unhealthy, damaged capillary with very high levels of insulin and glucose. Higher than normal levels of blood glucose lead to hyperglycemia. Hyperglycemia is the hallmark of prediabetes (between 100 and 125 mg/dL) and diabetes (126 mg/dL and higher). It is caused by either too little insulin being released by the pancreas or the body's inability to use insulin properly. Hyperglycemia leads to microangiopathy, marked by endothelial cell apoptosis (programmed cell death), accumulation of AGEs (advanced glycation end products), and thickening of the basement membrane, which can lead to the development of lesions, vasoconstriction, and altered vessel function
Interactive by TheVisualMD
Capillary within Muscle Tissue
Insulin and Glucose in Arteriole
Insulin Dispersion
Insulin Dispersion with Molecular Inset
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1) Capillary within Muscle Tissue 2) Insulin and Glucose in Arteriole 3) Insulin Dispersion 4) Insulin Disper
1) Capillary within Muscle Tissue - The body's blood vessels, consisting of arteries, veins, and capillaries, range in size from arteries as wide as a garden hose to capillaries so thin that it would take 10 of them, lined up side by side, to form the thickness of a human hair. But they all have one thing in common: they are designed to move blood as quickly and efficiently as possible. That means they need to be strong, flexible, and smooth. Even the components of your blood, like red blood cells, platelets, and white blood cells, are designed for movement. Red blood cells can actually flex so that they are able to flow through the finest of capillaries. Damage to blood vessels is something that all the main complications of diabetes have in common. Diabetes injures both large vessels (arteries) and small vessels (capillaries), leading to atherosclerosis and many other disorders. When the level of glucose in the blood is high, insulin signals certain cells, including muscle, fat, and liver cells, to take glucose in. Without insulin, glucose can't get into the cells, so it remains in the bloodstream. When blood glucose levels are too high (hyperglycemia), many serious health conditions can result. Cardiovascular disease (diseases of the heart and blood vessels) frequently accompanies diabetes because high levels of glucose act as a toxin to the lining of the blood vessels. About three quarters of people with diabetes die of cardiovascular disease.
2) Insulin and Glucose in Arteriole - GLUT4 is an insulin-regulated glucose transporter expressed primarily in muscle and fat cells. When GLUT4 cannot function properly, you develop insulin-resistance, leading to a buildup of glucose (pink) and insulin (yellow) in the bloodstream. Capillaries, the smallest blood vessels in your body, are where nutrients are transferred from blood to cells, and waste from cells to the blood. Too much glucose in the blood, a condition called hyperglycemia, leads to a number of problems including microangiopathy marked by endothelial cell apoptosis (programmed cell death), accumulation of AGEs (advanced glycation end products), and thickening of the basement membrane, which can lead to development of lesions, vasoconstriction, and altered vessel function.
3) Insulin Dispersion - Insulin is a potent hormone that has a powerful effect on many of the cells in the body. Rising glucose levels in the blood signal the pancreatic beta cells to produce and release greater amounts of insulin into the bloodstream. Without insulin, glucose would not be able to penetrate through cells' plasma membranes and enter into cell interiors. Glucose is the body's main and most vital fuel. In fact, some cells of the body, such as brain cells and red blood cells, use only glucose as fuel. Insulin causes skeletal muscle fiber cells, liver cells, fat cells, and red blood cells to take up glucose from the blood and use it for energy or store it as glycogen to prepare for energy needs, or (in the case of fat cells) use it to make fat. Insulin attaches to special sites on the cell membrane called insulin receptors. This attachment starts a long chain of events that lead to an increase in the number of glucose transporters, specialized protein molecules in the cell membrane. The glucose transporters form channels in the cell's membrane that allow glucose to enter the cell through a process called facilitated diffusion. The net result of all these insulin-mediated actions is the lowering of the glucose (blood sugar) level.
4) Insulin Dispersion with Molecular Inset - Insulin is a potent hormone that has a powerful effect on many of the cells in the body. Rising glucose levels in the blood signal the pancreatic beta cells to produce and release greater amounts of insulin into the bloodstream. Without insulin, glucose would not be able to penetrate through cells' plasma membranes and enter into cell interiors. Glucose is the body's main and most vital fuel. In fact, some cells of the body, such as brain cells and red blood cells, use only glucose as fuel. Insulin causes skeletal muscle fiber cells, liver cells, fat cells, and red blood cells to take up glucose from the blood and use it for energy or store it as glycogen to prepare for energy needs, or (in the case of fat cells) use it to make fat. Insulin attaches to special sites on the cell membrane called insulin receptors. This attachment starts a long chain of events that lead to an increase in the number of glucose transporters, specialized protein molecules in the cell membrane. The glucose transporters form channels in the cell's membrane that allow glucose to enter the cell through a process called facilitated diffusion. The net result of all these insulin-mediated actions is the lowering of the glucose (blood sugar) level.
Interactive by TheVisualMD
Index Finger with Translucent Skin
Index Finger with Translucent Skin and Blood Vessels
Index Finger with Translucent Skin, Blood Vessels, and Blood Drop
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Index Finger with Revealed Anatomy
Through the translucent skin in this image, you can see the intricate labyrinth of vessels that exist below the surface of the index finger. The web of vessels shown here represents only a fraction of the complex vascularization of our fingertips. When blood sugar levels get too high, such as in chronic diabetes, these delicate capillaries are usually the first vessels to suffer damage.
Interactive by TheVisualMD
Etymology of the disease diabetes mellitus
Etymology of the disease diabetes mellitus
Image by Dr Bilal Alshareef
Diabetes - The different types of diabetes and its treatment
Video by Healthchanneltv / cherishyourhealthtv/YouTube
What is Diabetes
Video by Centers for Disease Control and Prevention (CDC)/YouTube
What is Diabetes Mellitus? (Symptoms, Causes, Treatment, Prevention)
Video by healthery/YouTube
Complications of diabetes mellitus
TheVisualMD
Healthy Capillary Blood Vessel and and Damaged Capillary Blood Vessel Caused by High Levels of Blood Glucose
TheVisualMD
1) Capillary within Muscle Tissue 2) Insulin and Glucose in Arteriole 3) Insulin Dispersion 4) Insulin Disper
TheVisualMD
Index Finger with Revealed Anatomy
TheVisualMD
Etymology of the disease diabetes mellitus
Dr Bilal Alshareef
3:05
Diabetes - The different types of diabetes and its treatment
Healthchanneltv / cherishyourhealthtv/YouTube
2:31
What is Diabetes
Centers for Disease Control and Prevention (CDC)/YouTube
6:48
What is Diabetes Mellitus? (Symptoms, Causes, Treatment, Prevention)
healthery/YouTube
Diabetes Fast Facts
Depiction of a home test for diabetes, test results, and the 'big 3' symptoms of diabetes
Image by https://www.myupchar.com/en
Depiction of a home test for diabetes, test results, and the 'big 3' symptoms of diabetes
Depiction of a home test for diabetes, test results, and the 'big 3' symptoms of diabetes
Image by https://www.myupchar.com/en
Diabetes Fast Facts
The Big Picture
More than 34 million people in the United States have diabetes, and 1 in 5 of them don’t know they have it.
More than 88 million US adults—over a third—have prediabetes, and more than 80% of them don’t know they have it.
Diabetes is the 7 leading cause of death in the United States (and may be underreported).
Type 2 diabetes accounts for approximately 90% to 95% of all diagnosed cases of diabetes; type 1 diabetes accounts for approximately 5-10%.
In the last 20 years, the number of adults diagnosed with diabetes has more than doubled as the American population has aged and become more overweight or obese.
Cost
Medical costs and lost work and wages for people with diagnosed diabetes total $327 billion yearly.
Medical costs for people with diabetes are twice as high as for people who don’t have diabetes.
Source: Centers for Disease Control and Prevention (CDC)
Additional Materials (8)
Diabetes Type I and II
Three examples show normal functioning, defect in insulin production, and and defects in insulin receptors, representing normal, Type I and Type II diabetes. From a basic biology e-textbook by Dr. Cheryl Van Buskirk. Illustration by Jessie MNG Lopez
Image by Jessie MNG Lopez/Wikimedia
This browser does not support the video element.
Type 2 diabetes can be reversed
Animation of blood drop disappearing indicating reversal of diabetes.
Video by StoryMD
How Diabetes Damages Blood Vessels
How Diabetes Damages Blood Vessels - (left to right) Hard fatty deposits buildup inside the vessel wall, stiffening it and blocking blood flow; stiff, clogged heart arteries lead to angina and heart attack; clogged brain arteries and blood clots from plaques cause strokes.
Image by TheVisualMD
The global rise of diabetes—and how to prevent it | TED Institute
Video by TED Institute/YouTube
Surprising Facts About Diabetes
Video by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)/YouTube
Prevalence of Type 2 Diabetes in the US
Video by Stanford EdTech/YouTube
Coping with the emotional impact of diabetes I John's story I Diabetes UK
Video by Diabetes UK/YouTube
Adults with Type 2 diabetes
Adults with Diabetes : Type 2 diabetes is an epidemic in the US and all over the world. About 24 million Americans have diabetes-that's about 8% of the population.
Image by TheVisualMD
Diabetes Type I and II
Jessie MNG Lopez/Wikimedia
0:04
Type 2 diabetes can be reversed
StoryMD
How Diabetes Damages Blood Vessels
TheVisualMD
3:15
The global rise of diabetes—and how to prevent it | TED Institute
TED Institute/YouTube
0:48
Surprising Facts About Diabetes
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)/YouTube
4:22
Prevalence of Type 2 Diabetes in the US
Stanford EdTech/YouTube
3:26
Coping with the emotional impact of diabetes I John's story I Diabetes UK
Diabetes UK/YouTube
Adults with Type 2 diabetes
TheVisualMD
Risk Factors
Overweight
Image by TheVisualMD
Overweight
Researchers aren’t sure exactly how type 2 diabetes develops—why cells become insulin resistant and the pancreas eventually stops producing insulin—nor are they sure why some people develop type 2 diabetes and others don’t. But it is very clear that there are definite risk factors for type 2 diabetes.
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Diabetes Risk Factors
Type 1 Diabetes
Type 1 diabetes is thought to be caused by an immune reaction (the body attacks itself by mistake). Risk factors for type 1 diabetes are not as clear as for prediabetes and type 2 diabetes. Known risk factors include:
Family history: Having a parent, brother, or sister with type 1 diabetes.
Age: You can get type 1 diabetes at any age, but it’s more likely to develop when you’re a child, teen, or young adult.
In the United States, whites are more likely to develop type 1 diabetes than African Americans and Hispanic/Latino Americans.
Currently, no one knows how to prevent type 1 diabetes.
Type 2 Diabetes
You’re at risk for developing type 2 diabetes if you:
Have prediabetes
Are overweight
Are 45 years or older
Have a parent, brother, or sister with type 2 diabetes
Are physically active less than 3 times a week
Have ever had gestational diabetes (diabetes during pregnancy) or given birth to a baby who weighed more than 9 pounds
Are African American, Hispanic/Latino American, American Indian, or Alaska Native (some Pacific Islanders and Asian Americans are also at higher risk)
You can prevent or delay type 2 diabetes with simple, proven lifestyle changes such as losing weight if you’re overweight, eating healthier, and getting regular physical activity.
Prediabetes
You’re at risk for developing prediabetes if you:
Are overweight
Are 45 years or older
Have a parent, brother, or sister with type 2 diabetes
Are physically active less than 3 times a week
Have ever had gestational diabetes (diabetes during pregnancy) or given birth to a baby who weighed more than 9 pounds
Are African American, Hispanic/Latino American, American Indian, or Alaska Native (some Pacific Islanders and Asian Americans are also at higher risk)
You can prevent or reverse prediabetes with simple, proven lifestyle changes such as losing weight if you’re overweight, eating healthier, and getting regular physical activity. The CDC-led National Diabetes Prevention Program can help you make healthy changes that have lasting results.
Gestational Diabetes
You’re at risk for developing gestational diabetes (diabetes while pregnant) if you:
Had gestational diabetes during a previous pregnancy
Have given birth to a baby who weighed more than 9 pounds
Are overweight
Are more than 25 years old
Have a family history of type 2 diabetes
Have a hormone disorder called polycystic ovary syndrome (PCOS)
Are African American, Hispanic/Latino American, American Indian, Alaska Native, Native Hawaiian, or Pacific Islander
Gestational diabetes usually goes away after your baby is born but increases your risk for type 2 diabetes later in life. Your baby is more likely to have obesity as a child or teen, and is more likely to develop type 2 diabetes later in life too.
Before you get pregnant, you may be able to prevent gestational diabetes by losing weight if you’re overweight, eating healthier, and getting regular physical activity.
Source: Centers for Disease Control and Prevention (CDC)
Additional Materials (7)
Diabetes 101: Types, symptoms, risk factors and more
Video by Cleveland Clinic Martin Health/YouTube
Pre-Diabetes and Diabetes: Prevention, Screening and Risk Factors
Video by Ohio State Wexner Medical Center/YouTube
Help Teens Lower Their Risk for Type 2 Diabetes
Video by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)/YouTube
Diabetes and Stroke Risk: What You Need to Know
Video by American Heart Association/YouTube
Extruded Fat / Coronal View
Extruding Visceral Fat
Visceral fat is a type of body fat that’s stored within the abdominal cavity. It’s located near several vital organs, including the: liver, stomach, intestines. It can also build up in the arteries.
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Cross Section of African American male abdomen exposing extracorporeal fat and toxic visceral fat / Cross Section of abdomen exposing extracorporeal fat and toxic visceral fat
Cross Section of abdomen exposing extracorporeal fat and toxic visceral fat
Overweight and obesity are the primary risk factors for diabetes, especially if body fat is concentrated in the abdominal area. No fewer than 90% of people with type 2 diabetes are obese or overweight. Obesity is the most common cause of insulin resistance: the more adipose (fatty) tissue someone carries, the more resistant his or her cells become to insulin. The National Institutes of Health (NIH) and other health organizations as have defined obesity as a body mass index (BMI) of 30 and above. A BMI of 30 is about 30 pounds overweight.
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Childhood Obesity Worldwide
Childhood Obesity Worldwide : Childhood obesity is an epidemic around the globe. In the US, an estimated 17% of children and adolescents ages 2-19 are obese. In the last three decades, the percentage of obese children doubled in children ages 2-5 and tripled in children and adolescents ages 6-19. Up to 80% of obese youth become obese adults, who are at high risk for type 2 diabetes and cardiovascular disease-the leading cause of death in North America.
Image by TheVisualMD
4:06
Diabetes 101: Types, symptoms, risk factors and more
Cleveland Clinic Martin Health/YouTube
3:01
Pre-Diabetes and Diabetes: Prevention, Screening and Risk Factors
Ohio State Wexner Medical Center/YouTube
1:06
Help Teens Lower Their Risk for Type 2 Diabetes
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)/YouTube
2:59
Diabetes and Stroke Risk: What You Need to Know
American Heart Association/YouTube
Extruding Visceral Fat
TheVisualMD
Cross Section of abdomen exposing extracorporeal fat and toxic visceral fat
TheVisualMD
Childhood Obesity Worldwide
TheVisualMD
Symptoms
Diabetes Symptoms
Image by TheVisualMD
Diabetes Symptoms
Diabetes Symptoms : One of the reasons type 2 diabetes is so dangerous is that it can progress for months or years without symptoms. As many as 6 million Americans may have undiagnosed diabetes, according to the American Diabetes Association. By the time symptoms emerge, a great deal of damage may already have been done. That's why it's important to be tested by a doctor if you have risk factors for type 2 diabetes.
Image by TheVisualMD
What Are the Signs and Symptoms of Diabetes?
If you have any of the following diabetes symptoms, see your doctor about getting your blood sugar tested:
Urinate (pee) a lot, often at night
Are very thirsty
Lose weight without trying
Are very hungry
Have blurry vision
Have numb or tingling hands or feet
Feel very tired
Have very dry skin
Have sores that heal slowly
Have more infections than usual
Symptoms of Type 1 Diabetes
People who have type 1 diabetes may also have nausea, vomiting, or stomach pains. Type 1 diabetes symptoms can develop in just a few weeks or months and can be severe. Type 1 diabetes usually starts when you’re a child, teen, or young adult but can happen at any age.
Symptoms of Type 2 Diabetes
Type 2 diabetes symptoms often develop over several years and can go on for a long time without being noticed (sometimes there aren’t any noticeable symptoms at all). Type 2 diabetes usually starts when you’re an adult, though more and more children, teens, and young adults are developing it. Because symptoms are hard to spot, it’s important to know the risk factors for type 2 diabetes and visit your doctor if you have any of them.
Symptoms of Gestational Diabetes
Gestational diabetes (diabetes during pregnancy) usually shows up in the middle of the pregnancy and typically doesn’t have any symptoms. If you’re pregnant, you should be tested for gestational diabetes between 24 and 28 weeks of pregnancy so you can make changes if needed to protect your health and your baby’s health.
Source: Centers for Disease Control and Prevention (CDC)
Additional Materials (5)
Signs & Symptoms of Diabetes
Video by Diabetes - What To Know/YouTube
What is Diabetes Mellitus? (Symptoms, Causes, Treatment, Prevention)
Video by healthery/YouTube
Diabetes Excessive Hunger | No 1 Of 10 Type 2 Diabetes Signs And Symptoms
Video by Early Diabetes Symptoms/YouTube
Symptoms of Diabetes (Diabetes #2)
Video by Healthguru/YouTube
Fatigue
Weight Loss
Constant Hunger
Increased Thirst
Frequent Urination
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Diabetes Symptoms
1) Fatigue: dehydration, lack of ability to utilize glucose for energy and other factors cause fatigue
2) Weight loss: because it can't use glucose for energy, the body breaks down muscle instead; constant hunger
3) Constant hunger: diabetes prevents glucose from entering cells, leading to constant hunger due to cell starvation
4) Increased thirst: too much urination leaves tissues dehydrated and causes increased thirst
5) Frequent urination: fluids are drawn from tissues and the kidneys constantly filter out glucose, leading to frequent urination
Interactive by TheVisualMD
2:37
Signs & Symptoms of Diabetes
Diabetes - What To Know/YouTube
6:48
What is Diabetes Mellitus? (Symptoms, Causes, Treatment, Prevention)
healthery/YouTube
4:07
Diabetes Excessive Hunger | No 1 Of 10 Type 2 Diabetes Signs And Symptoms
Early Diabetes Symptoms/YouTube
2:56
Symptoms of Diabetes (Diabetes #2)
Healthguru/YouTube
Diabetes Symptoms
TheVisualMD
Prediabetes
Exercise to Both Prevent and Treat Diabetes
Image by TheVisualMD
Exercise to Both Prevent and Treat Diabetes
Exercise works like a wonder drug for diabetes. That's because exercise gets both your muscles and your liver to take up more glucose, lowering your blood sugar levels (pink particles).
Image by TheVisualMD
Prediabetes - Your Chance to Prevent Type 2 Diabetes
What Is Prediabetes?
Prediabetes is a serious health condition where blood sugar levels are higher than normal, but not high enough yet to be diagnosed as type 2 diabetes. Approximately 88 million American adults—more than 1 in 3—have prediabetes. Of those with prediabetes, more than 84% don’t know they have it. Prediabetes puts you at increased risk of developing type 2 diabetes, heart disease, and stroke.
The good news is that if you have prediabetes, the CDC-led National Diabetes Prevention Program can help you make lifestyle changes to prevent or delay type 2 diabetes and other serious health problems.
What Causes Prediabetes?
Insulin is a hormone made by your pancreas that acts like a key to let blood sugar into cells for use as energy. If you have prediabetes, the cells in your body don’t respond normally to insulin. Your pancreas makes more insulin to try to get cells to respond. Eventually your pancreas can’t keep up, and your blood sugar rises, setting the stage for prediabetes—and type 2 diabetes down the road.
Signs & Symptoms
You can have prediabetes for years but have no clear symptoms, so it often goes undetected until serious health problems such as type 2 diabetes show up. It’s important to talk to your doctor about getting your blood sugar tested if you have any of the risk factors for prediabetes, which include:
Being overweight
Being 45 years or older
Having a parent, brother, or sister with type 2 diabetes
Being physically active less than 3 times a week
Ever having gestational diabetes (diabetes during pregnancy) or giving birth to a baby who weighed more than 9 pounds
Having polycystic ovary syndrome
Race and ethnicity are also a factor: African Americans, Hispanic/Latino Americans, American Indians, Pacific Islanders, and some Asian Americans are at higher risk.
Simple Blood Sugar Test
You can get a simple blood sugar test to find out if you have prediabetes. Ask your doctor if you should be tested.
Preventing Type 2 Diabetes
If you have prediabetes, losing a small amount of weight if you’re overweight and getting regular physical activity can lower your risk for developing type 2 diabetes. A small amount of weight loss means around 5% to 7% of your body weight, just 10 to 14 pounds for a 200-pound person. Regular physical activity means getting at least 150 minutes a week of brisk walking or a similar activity. That’s just 30 minutes a day, five days a week.
Source: Centers for Disease Control and Prevention (CDC)
Additional Materials (13)
One woman’s story of reversing prediabetes
Video by Vanderbilt Health/YouTube
A1C test for diabetes C prediabetes
Video by NIH Clinical Center/YouTube
Reversing Prediabetes
Video by Centers for Disease Control and Prevention (CDC)/YouTube
Do you know the risk factors for prediabetes and type 2 diabetes?
Video by Hormone Health Network/YouTube
What Is Prediabetes?
Video by My Doctor - Kaiser Permanente/YouTube
Learn More about Prediabetes
Video by My Doctor - Kaiser Permanente/YouTube
Mike's Prediabetes Journey | Type 2 Diabetes Prevention | Ad Council
Video by Do I Have Prediabetes/YouTube
PreventT2-prediabetes-spanish
Video by Centers for Disease Control and Prevention (CDC)/YouTube
Prediabetes: How to Reduce the Risks of Developing Diabetes
Video by Cone Health/YouTube
How to Prevent and Treat Prediabetes
Video by Sharp HealthCare/YouTube
Blood Sugar Gone Awry
We are made entirely of cells, and the cells of the body depend on sugar in the blood, derived from carbohydrates, for food and energy. Allowing for the innumerable differences among individuals, the threshold for a normal blood-sugar (glucose) level in healthy people is 100 mg/dL; that is, 100 milligrams of glucose per deciliter of blood. Lower-than-normal levels characterize hypoglycemia and higher than normal levels hyperglycemia. Hypoglycemia, indicated around 70 mg/dL and lower, can be traced to three causes. The body may be using up the available blood sugar (glucose), or the glucose ingested may be released into the blood stream too slowly. It's also possible that too much insulin is being released. Hyperglycemia is the hallmark of prediabetes (between 100 and 125 mg/dL) and diabetes (126 mg/dL and higher). It is caused by either too little insulin being released by the pancreas or the body`s inability to use insulin properly.
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Live Well
To keep your blood vessels healthy and clear, prevention is the best medicine. Eat a diet low in saturated fats and high in fruits, vegetables, nuts, and whole grains. If you smoke, quit, and if you don't smoke, don't start. Have regular checkups and keep track of your cholesterol levels and blood pressure readings. Manage chronic conditions, like diabetes, that can damage blood vessels and cause heart disease if uncontrolled. Staying active is key: your body was made to move. Exercise not only reduces your risk of cardiovascular disease, it also reduces stress and helps prevent many other diseases, including cancer.
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Glycemic Index
Eating right can lower your blood sugar, LDL-cholesterol, and triglyceride levels. Healthy foods in the right amounts can help to keep your glucose levels stable, too, and slow or prevent diabetes complications. The glycemic index (GI) classifies carbohydrates based on how quickly and how much they boost blood sugar compared to pure glucose. Choose low-GI foods are best for keeping blood sugar levels down.
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One woman’s story of reversing prediabetes
Vanderbilt Health/YouTube
2:26
A1C test for diabetes C prediabetes
NIH Clinical Center/YouTube
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Reversing Prediabetes
Centers for Disease Control and Prevention (CDC)/YouTube
1:36
Do you know the risk factors for prediabetes and type 2 diabetes?
Hormone Health Network/YouTube
2:20
What Is Prediabetes?
My Doctor - Kaiser Permanente/YouTube
2:13
Learn More about Prediabetes
My Doctor - Kaiser Permanente/YouTube
3:26
Mike's Prediabetes Journey | Type 2 Diabetes Prevention | Ad Council
Do I Have Prediabetes/YouTube
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PreventT2-prediabetes-spanish
Centers for Disease Control and Prevention (CDC)/YouTube
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Prediabetes: How to Reduce the Risks of Developing Diabetes
Cone Health/YouTube
53:26
How to Prevent and Treat Prediabetes
Sharp HealthCare/YouTube
Blood Sugar Gone Awry
TheVisualMD
Live Well
TheVisualMD
Glycemic Index
TheVisualMD
Type 1 Diabetes
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What Is Type 1 Diabetes?
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What Is Type 1 Diabetes?
The story of type 1 diabetes begins with your pancreas and your immune system. Your pancreas runs across the back of your abdomen, behind your stomach. The pancreas contains beta cells which produce insulin. Insulin is a hormone that signals your body's cells to take in energy in the form of blood glucose (also known as blood sugar). In type 1 diabetes, the pancreatic beta cells produce little or no insulin because the body's immune system destroys the pancreatic cells that produce insulin. The result is that without insulin, glucose cannot enter cells to provide energy. The body's cells begin to starve, leading to these symptoms: fatigue, weight loss, constant hunger, increased thirst, and frequent urination. When glucose cannot enter cells, it builds up in the bloodstream, leading to harmful complications such as cardiovascular disease, heart attacks, strokes, kidney disease, vision damage, and nerve damage.
Video by TheVisualMD
What Is Type 1 Diabetes?
If you have type 1 diabetes, your pancreas doesn’t make insulin or makes very little insulin. Insulin helps blood sugar enter the cells in your body for use as energy. Without insulin, blood sugar can’t get into cells and builds up in the bloodstream. High blood sugar is damaging to the body and causes many of the symptoms and complications of diabetes.
Type 1 diabetes was once called insulin-dependent or juvenile diabetes. It usually develops in children, teens, and young adults, but it can happen at any age.
Type 1 diabetes is less common than type 2—about 5-10% of people with diabetes have type 1. Currently, no one knows how to prevent type 1 diabetes, but it can be treated successfully by:
Following your doctor’s recommendations for living a healthy lifestyle.
Managing your blood sugar.
Getting regular health checkups.
Getting diabetes self-management education and support.
For Parents
If your child has type 1 diabetes—especially a young child—you’ll handle diabetes care on a day-to-day basis. Daily care will include serving healthy foods, giving insulin injections, and watching for and treating hypoglycemia (low blood sugar). You’ll also need to stay in close contact with your child’s health care team. They will help you understand the treatment plan and how to help your child stay healthy.
What Causes Type 1 Diabetes?
Type 1 diabetes is thought to be caused by an autoimmune reaction (the body attacks itself by mistake). This reaction destroys the cells in the pancreas that make insulin, called beta cells. This process can go on for months or years before any symptoms appear.
Some people have certain genes (traits passed on from parent to child) that make them more likely to develop type 1 diabetes. However, many of them won’t go on to have type 1 diabetes even if they have the genes. A trigger in the environment, such as a virus, may also play a part in developing type 1 diabetes. Diet and lifestyle habits don’t cause type 1 diabetes.
Symptoms and Risk Factors
It can take months or years before symptoms of type 1 diabetes are noticed. Type 1 diabetes symptoms can develop in just a few weeks or months. Once symptoms appear, they can be severe.
Some type 1 diabetes symptoms are similar to symptoms of other health conditions. Don’t guess! If you think you could have type 1 diabetes, see your doctor to get your blood sugar tested. Untreated diabetes can lead to very serious—even fatal—health problems.
Risk factors for type 1 diabetes are not as clear as for prediabetes and type 2 diabetes. However, studies show that family history plays a part.
Testing for Type 1 Diabetes
A simple blood test will let you know if you have diabetes. If you were tested at a health fair or pharmacy, follow up at a clinic or doctor’s office. That way you’ll be sure the results are accurate.
If your doctor thinks you have type 1 diabetes, your blood may also be tested for autoantibodies. These substances indicate your body is attacking itself and are often found with type 1 diabetes but not with type 2. You may have your urine tested for ketones too. Ketones are produced when your body burns fat for energy. Having ketones in your urine indicates you have type 1 diabetes instead of type 2.
Managing Diabetes
Unlike many health conditions, diabetes is managed mostly by you, with support from your health care team:
Primary care doctor
Foot doctor
Dentist
Eye doctor
Registered dietitian nutritionist
Diabetes educator
Pharmacist
Also ask your family, teachers, and other important people in your life for help and support. Managing diabetes can be challenging, but everything you do to improve your health is worth it!
If you have type 1 diabetes, you’ll need to take insulin shots (or wear an insulin pump) every day. Insulin is needed to manage your blood sugar levels and give your body energy. You can’t take insulin as a pill. That’s because the acid in your stomach would destroy it before it could get into your bloodstream. Your doctor will work with you to figure out the most effective type and dosage of insulin for you.
You’ll also need to do regular blood sugar checks. Ask your doctor how often you should check it and what your target blood sugar levels should be. Keeping your blood sugar levels as close to target as possible will help you prevent or delay diabetes-related complications.
Stress is a part of life, but it can make managing diabetes harder. Both managing your blood sugar levels and dealing with daily diabetes care can be tougher to do. Regular physical activity, getting enough sleep, and exercises to relax can help. Talk to your doctor and diabetes educator about these and other ways you can manage stress.
Healthy lifestyle habits are really important too:
Making healthy food choices
Being physically active
Controlling your blood pressure
Controlling your cholesterol
Make regular appointments with your health care team. They’ll help you stay on track with your treatment plan and offer new ideas and strategies if needed.
Hypoglycemia and Diabetic Ketoacidosis
These 2 conditions are common complications of diabetes, and you’ll need to know how to handle them. Meet with your doctor for step-by-step instructions. You may want to bring a family member with you to the appointment so they learn the steps too.
Hypoglycemia (low blood sugar) can happen quickly and needs to be treated quickly. It’s most often caused by:
Too much insulin.
Waiting too long for a meal or snack.
Not eating enough.
Getting extra physical activity.
Talk to your doctor if you have low blood sugar several times a week. Your treatment plan may need to be changed.
Diabetic ketoacidosis (DKA) is a serious complication of diabetes that can be life-threatening. DKA develops when you don’t have enough insulin to let blood sugar into your cells. Very high blood sugar and low insulin levels lead to DKA. The two most common causes are illness and missing insulin shots. Talk with your doctor and make sure you understand how you can prevent and treat DKA.
Get Diabetes Education
Meeting with a diabetes educator is a great way to get support and guidance, including how to:
Develop and stick to a healthy eating and activity plan
Test your blood sugar and keep a record of the results
Recognize the signs of high or low blood sugar and what to do about it
Give yourself insulin by syringe, pen, or pump
Monitor your feet, skin, and eyes to catch problems early
Buy diabetes supplies and store them properly
Manage stress and deal with daily diabetes care
Ask your doctor about diabetes self-management education and support services and to recommend a diabetes educator. You can also search this nationwide directory for a list of programs in your community.
Get Support
Tap into online diabetes communities for encouragement, insights, and support. Check out the American Diabetes Association’s Community page and JDRF’s TypeOneNation. Both are great ways to connect with others who share your experience.
Source: Centers for Disease Control and Prevention (CDC)
Additional Materials (2)
Type 1 Diabetes Defined
Type 1 Diabetes Defined
Image by TheVisualMD
3D medical animation still of type 1 diabetes
3D medical animation still of Type 1 Diabetes showing lower amount of insulin production in a diabetic patient.
Image by Scientific Animations, Inc.
Type 1 Diabetes Defined
TheVisualMD
3D medical animation still of type 1 diabetes
Scientific Animations, Inc.
Type 2 Diabetes
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What Is Type 2 Diabetes?
Video by TheVisualMD
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What Is Type 2 Diabetes?
Go deep inside your body to see how type 2 diabetes happens, what it does to your body-and what you can do about it. Diabetes expert Dr. David Katz of the Yale Prevention Research Center talks about the frightening future of diabetes: in just a few decades, one third of all Americans may have diabetes. See the pancreas, where insulin is produced. Real imaging data reveals the body's inner anatomy slice by slice, from brain to base of spine. Dr. Cynthia Geyer of Canyon Ranch talks about how insulin resistance develops. View its results, as visceral abdominal fat builds up and chokes the vital organs. Discover the symptoms of type 2 diabetes and find out if you should be tested. See the complications of diabetes, including cardiovascular disease, hypertension, vision damage, kidney disease, and gangrene. The good news? Diabetes is a highly manageable disease. Dr. Mark Liponis of Canyon Ranch talks about controlling your risk for type 2 diabetes and, by managing it, reversing its symptoms and literally slowing the aging process.
Video by TheVisualMD
What Is Type 2 Diabetes?
More than 34 million Americans have diabetes (about 1 in 10), and approximately 90-95% of them have type 2 diabetes. Type 2 diabetes most often develops in people over age 45, but more and more children, teens, and young adults are also developing it.
What Causes Type 2 Diabetes?
Insulin is a hormone made by your pancreas that acts like a key to let blood sugar into the cells in your body for use as energy. If you have type 2 diabetes, cells don’t respond normally to insulin; this is called insulin resistance. Your pancreas makes more insulin to try to get cells to respond. Eventually your pancreas can’t keep up, and your blood sugar rises, setting the stage for prediabetes and type 2 diabetes. High blood sugar is damaging to the body and can cause other serious health problems, such as heart disease, vision loss, and kidney disease.
Symptoms and Risk Factors
Type 2 diabetes symptoms often develop over several years and can go on for a long time without being noticed (sometimes there aren’t any noticeable symptoms at all). Because symptoms can be hard to spot, it’s important to know the risk factors and to see your doctor to get your blood sugar tested if you have any of them.
Testing for Type 2 Diabetes
A simple blood test will let you know if you have diabetes. If you’ve gotten your blood sugar tested at a health fair or pharmacy, follow up at a clinic or doctor’s office to make sure the results are accurate.
Managing Diabetes
Unlike many health conditions, diabetes is managed mostly by you, with support from your health care team (including your primary care doctor, foot doctor, dentist, eye doctor, registered dietitian nutritionist, diabetes educator, and pharmacist), family, and other important people in your life. Managing diabetes can be challenging, but everything you do to improve your health is worth it!
You may be able to manage your diabetes with healthy eating and being active, or your doctor may prescribe insulin, other injectable medications, or oral diabetes medicines to help manage your blood sugar and avoid complications. You’ll still need to eat healthy and be active if you take insulin or other medicines. It’s also important to keep your blood pressure and cholesterol close to the targets your doctor sets for you and get necessary screening tests.
You’ll need to check your blood sugar regularly. Ask your doctor how often you should check it and what your target blood sugar levels should be. Keeping your blood sugar levels as close to target as possible will help you prevent or delay diabetes-related complications.
Stress is a part of life, but it can make managing diabetes harder, including managing your blood sugar levels and dealing with daily diabetes care. Regular physical activity, getting enough sleep, and relaxation exercises can help. Talk to your doctor and diabetes educator about these and other ways you can manage stress.
Make regular appointments with your health care team to be sure you’re on track with your treatment plan and to get help with new ideas and strategies if needed.
Whether you were just diagnosed with diabetes or have had it for some time, meeting with a diabetes educator is a great way to get support and guidance, including how to:
Develop a healthy eating and activity plan
Test your blood sugar and keep a record of the results
Recognize the signs of high or low blood sugar and what to do about it
If needed, give yourself insulin by syringe, pen, or pump
Monitor your feet, skin, and eyes to catch problems early
Buy diabetes supplies and store them properly
Manage stress and deal with daily diabetes care
Ask your doctor about diabetes self-management education and support services and to recommend a diabetes educator, or search the Association of Diabetes Care & Education Specialists’ (ADCES) nationwide directory for a list of programs in your community.
Type 2 Diabetes in Children and Teens
Childhood obesity rates are rising, and so are the rates of type 2 diabetes in youth. More than 75% of children with type 2 diabetes have a close relative who has it, too. But it’s not always because family members are related; it can also be because they share certain habits that can increase their risk. Parents can help prevent or delay type 2 diabetes by developing a plan for the whole family:
Drinking more water and fewer sugary drinks
Eating more fruits and vegetables
Making favorite foods healthier
Making physical activity more fun
Healthy changes become habits more easily when everyone makes them together.
Source: Centers for Disease Control and Prevention (CDC)
Additional Materials (14)
A Critical Balance
Key Players
The Fuel Supply Chain
Diabetes Symptoms
Overweight
Diabetes and Large Vessel Disease
Diabetes and Small Vessel Disease
Nerve Damage
Testing and Diagnosis
Keep It Down
Health in Action
Put Out the Fire
Calming Diabetes
Keeping Tabs on Glucose
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Diabetes in the US
Interactive by TheVisualMD
Diabetes and the body | Diabetes UK
Video by Diabetes UK/YouTube
Diabetes and emotional wellbeing | Zena's story | Diabetes UK
Video by Diabetes UK/YouTube
Diabetes and mental health I What can help I Diabetes UK
Video by Diabetes UK/YouTube
Make emotional health a part of diabetes care | It's missing | Diabetes UK
Video by Diabetes UK/YouTube
Diabetes - The different types of diabetes and its treatment
Video by Healthchanneltv / cherishyourhealthtv/YouTube
Understanding Type 2 Diabetes
Video by Animated Diabetes Patient/YouTube
What is Diabetes? (Animation)
Video by Blausen Medical Corporate/YouTube
What is Type 2 Diabetes?
Video by ClearlyHealth/YouTube
Diabetes 2: Basics of Diabetes
Video by Craig Blackwell/YouTube
Diabetes: Everything You Need to Know
Video by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)/YouTube
Type 1 vs. Type 2 Diabetes Medical Course
Video by Abiezer Abigail/YouTube
Diabetes Type 1 and Type 2, Animation.
Video by Alila Medical Media/YouTube
A Fact Sheet From the Office on Women's Health Q+A Diabetes
A Fact Sheet From the Office on Women's Health Q+A Diabetes
Document by Office on Women's Health, U.S. Department of Health and Human Services
Diabetes in the US
TheVisualMD
8:45
Diabetes and the body | Diabetes UK
Diabetes UK/YouTube
3:38
Diabetes and emotional wellbeing | Zena's story | Diabetes UK
Diabetes UK/YouTube
1:53
Diabetes and mental health I What can help I Diabetes UK
Diabetes UK/YouTube
1:04
Make emotional health a part of diabetes care | It's missing | Diabetes UK
Diabetes UK/YouTube
3:05
Diabetes - The different types of diabetes and its treatment
Healthchanneltv / cherishyourhealthtv/YouTube
3:46
Understanding Type 2 Diabetes
Animated Diabetes Patient/YouTube
0:33
What is Diabetes? (Animation)
Blausen Medical Corporate/YouTube
2:02
What is Type 2 Diabetes?
ClearlyHealth/YouTube
10:02
Diabetes 2: Basics of Diabetes
Craig Blackwell/YouTube
0:30
Diabetes: Everything You Need to Know
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)/YouTube
4:24
Type 1 vs. Type 2 Diabetes Medical Course
Abiezer Abigail/YouTube
3:46
Diabetes Type 1 and Type 2, Animation.
Alila Medical Media/YouTube
A Fact Sheet From the Office on Women's Health Q+A Diabetes
Office on Women's Health, U.S. Department of Health and Human Services
Gestational Diabetes
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Gestational diabetes
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Gestational diabetes
In a healthy body, the pancreatic hormones insulin and glucagon perform their back-and-forth dance perfectly, and blood sugar level stays in its normal, narrow range. But in diabetes, this careful balance is upset.
Image by TheVisualMD
What Is Gestational Diabetes?
Gestational diabetes is a type of diabetes that can develop during pregnancy in women who don’t already have diabetes. Every year, 2% to 10% of pregnancies in the United States are affected by gestational diabetes. Managing gestational diabetes will help make sure you have a healthy pregnancy and a healthy baby.
What Causes Gestational Diabetes?
Gestational diabetes occurs when your body can’t make enough insulin during your pregnancy. Insulin is a hormone made by your pancreas that acts like a key to let blood sugar into the cells in your body for use as energy.
During pregnancy, your body makes more hormones and goes through other changes, such as weight gain. These changes cause your body’s cells to use insulin less effectively, a condition called insulin resistance. Insulin resistance increases your body’s need for insulin.
All pregnant women have some insulin resistance during late pregnancy. However, some women have insulin resistance even before they get pregnant. They start pregnancy with an increased need for insulin and are more likely to have gestational diabetes.
Symptoms and Risk Factors
Gestational diabetes typically doesn’t have any symptoms. Your medical history and whether you have any risk factors may suggest to your doctor that you could have gestational diabetes, but you’ll need to be tested to know for sure.
Related Health Problems
Having gestational diabetes can increase your risk of high blood pressure during pregnancy. It can also increase your risk of having a large baby that needs to be delivered by cesarean section (C-section).
If you have gestational diabetes, your baby is at higher risk of:
Being very large (9 pounds or more), which can make delivery more difficult
Being born early, which can cause breathing and other problems
Having low blood sugar
Developing type 2 diabetes later in life
Your blood sugar levels will usually return to normal after your baby is born. However, about 50% of women with gestational diabetes go on to develop type 2 diabetes. You can lower your risk by reaching a healthy body weight after delivery. Visit your doctor to have your blood sugar tested 6 to 12 weeks after your baby is born and then every 1 to 3 years to make sure your levels are on target.
Testing for Gestational Diabetes
It’s important to be tested for gestational diabetes so you can begin treatment to protect your health and your baby’s health.
Gestational diabetes usually develops around the 24 week of pregnancy, so you’ll probably be tested between 24 and 28 weeks.
If you’re at higher risk for gestational diabetes, your doctor may test you earlier. Blood sugar that’s higher than normal early in your pregnancy may indicate you have type 1 or type 2 diabetes rather than gestational diabetes.
Prevention
Before you get pregnant, you may be able to prevent gestational diabetes by losing weight if you’re overweight and getting regular physical activity.
Don’t try to lose weight if you’re already pregnant. You’ll need to gain some weight—but not too quickly—for your baby to be healthy. Talk to your doctor about how much weight you should gain for a healthy pregnancy.
Treatment for Gestational Diabetes
You can do a lot to manage your gestational diabetes. Go to all your prenatal appointments and follow your treatment plan, including:
Checking your blood sugar to make sure your levels stay in a healthy range.
Eating healthy food in the right amounts at the right times. Follow a healthy eating plan created by your doctor or dietitian.
Being active. Regular physical activity that’s moderately intense (such as brisk walking) lowers your blood sugar and makes you more sensitive to insulin so your body won’t need as much. Make sure to check with your doctor about what kind of physical activity you can do and if there are any kinds you should avoid.
Monitoring your baby. Your doctor will check your baby’s growth and development.
If healthy eating and being active aren’t enough to manage your blood sugar, your doctor may prescribe insulin, metformin, or other medication.
Source: Centers for Disease Control and Prevention (CDC)
Additional Materials (4)
Diabetes During Pregnancy: What is Gestational Diabetes?
Video by American Diabetes Association/YouTube
Gestational Diabetes Symptoms: Act now before it is too late!
Video by Kids In The House/YouTube
Gestational Diabetes (Pregnancy Health Guru)
Video by Healthguru/YouTube
What is Gestational Diabetes?
Video by My Doctor - Kaiser Permanente/YouTube
2:38
Diabetes During Pregnancy: What is Gestational Diabetes?
American Diabetes Association/YouTube
2:51
Gestational Diabetes Symptoms: Act now before it is too late!
Kids In The House/YouTube
2:15
Gestational Diabetes (Pregnancy Health Guru)
Healthguru/YouTube
1:55
What is Gestational Diabetes?
My Doctor - Kaiser Permanente/YouTube
Testing
Are you on the road to type 2 Diabetes?
Image by CDC
Are you on the road to type 2 Diabetes?
Are you on the road to type 2 Diabetes?
Image by CDC
Diabetes Tests
You’ll need to get your blood sugar tested to find out for sure if you have prediabetes or type 1, type 2, or gestational diabetes. Testing is simple, and results are usually available quickly.
Tests for Type 1 Diabetes, Type 2 Diabetes, and Prediabetes
Your doctor will have you take one or more of the following blood tests to confirm the diagnosis:
A1C Test
The A1C test measures your average blood sugar level over the past 2 or 3 months. An A1C below 5.7% is normal, between 5.7 and 6.4% indicates you have prediabetes, and 6.5% or higher indicates you have diabetes.
Fasting Blood Sugar Test
This measures your blood sugar after an overnight fast (not eating). A fasting blood sugar level of 99 mg/dL or lower is normal, 100 to 125 mg/dL indicates you have prediabetes, and 126 mg/dL or higher indicates you have diabetes.
Glucose Tolerance Test
This measures your blood sugar before and after you drink a liquid that contains glucose. You’ll fast (not eat) overnight before the test and have your blood drawn to determine your fasting blood sugar level. Then you’ll drink the liquid and have your blood sugar level checked 1 hour, 2 hours, and possibly 3 hours afterward. At 2 hours, a blood sugar level of 140 mg/dL or lower is considered normal, 140 to 199 mg/dL indicates you have prediabetes, and 200 mg/dL or higher indicates you have diabetes.
Random Blood Sugar Test
This measures your blood sugar at the time you’re tested. You can take this test at any time and don’t need to fast (not eat) first. A blood sugar level of 200 mg/dL or higher indicates you have diabetes.
Result*
A1C Test
Fasting Blood Sugar Test
Glucose Tolerance Test
Random Blood Sugar Test
Diabetes
6.5% or above
126 mg/dL or above
200 mg/dL or above
200 mg/dL or above
Prediabetes
5.7 – 6.4%
100 – 125 mg/dL
140 – 199 mg/dL
N/A
Normal
Below 5.7%
99 mg/dL or below
140 mg/dL or below
N/A
*Results for gestational diabetes can differ. Ask your health care provider what your results mean if you’re being tested for gestational diabetes. Source: American Diabetes Association
If your doctor thinks you have type 1 diabetes, your blood may also tested for autoantibodies (substances that indicate your body is attacking itself) that are often present in type 1 diabetes but not in type 2 diabetes. You may have your urine tested for ketones (produced when your body burns fat for energy), which also indicate type 1 diabetes instead of type 2 diabetes.
Tests for Gestational Diabetes
Gestational diabetes is diagnosed using blood tests. You’ll probably be tested between 24 and 28 weeks of pregnancy. If your risk is higher for getting gestational diabetes (due to having more risk factors), your doctor may test you earlier. Blood sugar that’s higher than normal early in your pregnancy may indicate you have type 1 or type 2 diabetes rather than gestational diabetes.
Glucose Screening Test
This measures your blood sugar at the time you’re tested. You’ll drink a liquid that contains glucose, and then 1 hour later your blood will be drawn to check your blood sugar level. A normal result is 140 mg/dL or lower. If your level is higher than 140 mg/dL, you’ll need to take a glucose tolerance test.
Glucose Tolerance Test
This measures your blood sugar before and after you drink a liquid that contains glucose. You’ll fast (not eat) overnight before the test and have your blood drawn to determine your fasting blood sugar level. Then you’ll drink the liquid and have your blood sugar level checked 1 hour, 2 hours, and possibly 3 hours afterward. Results can differ depending on the size of the glucose drink and how often your blood sugar is tested. Ask your doctor what your test results mean.
Prevent Type 2 Diabetes
If your test results show you have prediabetes, ask your doctor or nurse if there is a lifestyle change program offered through the CDC-led National Diabetes Prevention Program in your community. You can also search for an online or in-person program. Having prediabetes puts you at greater risk for developing type 2 diabetes, but participating in the program can lower your risk by as much as 58% (71% if you’re over age 60).
Diabetes Treatment Plan
If your test results show you have type 1, type 2, or gestational diabetes, talk with your doctor or nurse about a detailed treatment plan—including diabetes self-management education and support services—and specific steps you can take to be your healthiest.
Source: Centers for Disease Control and Prevention (CDC)
Additional Materials (10)
Index Finger with Translucent Skin
Index Finger with Translucent Skin and Blood Vessels
Index Finger with Translucent Skin, Blood Vessels, and Blood Drop
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Index Finger with Revealed Anatomy
Through the translucent skin in this image, you can see the intricate labyrinth of vessels that exist below the surface of the index finger. The web of vessels shown here represents only a fraction of the complex vascularization of our fingertips. When blood sugar levels get too high, such as in chronic diabetes, these delicate capillaries are usually the first vessels to suffer damage.
Interactive by TheVisualMD
Diagnosing diabetes | Endocrine system diseases | NCLEX-RN | Khan Academy
Video by khanacademymedicine/YouTube
Glucose Challenge Test during Pregnancy | 1mg Lab Test
Video by Tata 1mg/YouTube
Glucose Tolerance Test (Obstetrics - Third Trimester)
Video by Med Twice/YouTube
Checking Blood Sugar (Glucose) Level | How to Use a Glucometer (Glucose Meter)
Video by RegisteredNurseRN/YouTube
Glucose Insulin and Diabetes
Video by Khan Academy/YouTube
Testing Glucose or Ketones: Which is More Important?
Video by Dr. Eric Berg DC/YouTube
How HbA1c testing detects glucose in your body for diabetes type 2
Video by Pathology Tests Explained/YouTube
Depiction of a home test for diabetes, test results, and the 'big 3' symptoms of diabetes
Depiction of a home test for diabetes, test results, and the 'big 3' symptoms of diabetes
Image by https://www.myupchar.com/en
Testing and Diagnosing Diabetes
Several tests are used to diagnose prediabetes and diabetes. In June 2009, the ADA, the European Association for the Study of Diabetes, and the International Diabetes Federation made a joint recommendation that type 2 diabetes testing include the glycated hemoglobin (A1C) test. This test measures average blood glucose level during the past 2-3 months by measuring the percentage of glucose attached to hemoglobin, the oxygen-carrying protein pigment in red blood cells.
Image by TheVisualMD
Index Finger with Revealed Anatomy
TheVisualMD
8:23
Diagnosing diabetes | Endocrine system diseases | NCLEX-RN | Khan Academy
khanacademymedicine/YouTube
1:47
Glucose Challenge Test during Pregnancy | 1mg Lab Test
Tata 1mg/YouTube
2:47
Glucose Tolerance Test (Obstetrics - Third Trimester)
Med Twice/YouTube
10:43
Checking Blood Sugar (Glucose) Level | How to Use a Glucometer (Glucose Meter)
RegisteredNurseRN/YouTube
7:24
Glucose Insulin and Diabetes
Khan Academy/YouTube
6:39
Testing Glucose or Ketones: Which is More Important?
Dr. Eric Berg DC/YouTube
2:28
How HbA1c testing detects glucose in your body for diabetes type 2
Pathology Tests Explained/YouTube
Depiction of a home test for diabetes, test results, and the 'big 3' symptoms of diabetes
https://www.myupchar.com/en
Testing and Diagnosing Diabetes
TheVisualMD
How to Get Screened for Diabetes?
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Blood Glucose and Baselining Your Health
Video by TheVisualMD
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Blood Glucose and Baselining Your Health
Our bodies and brains run on glucose, a simple sugar produced by the digestion of carbohydrates. The body's ability to use glucose depends on the hormone insulin, which is produced by the pancreas. Blood sugar levels naturally rise after meals, but insulin from a healthy pancreas keeps these levels within a narrow range. In diabetes, however, this balance is disrupted because either the body loses its ability to respond to insulin or the pancreas loses its ability to produce insulin. Too much or too little glucose in the bloodstream can damage blood vessels in the kidneys and eyes, as well as nerve cells; acute disruptions of the insulin/glucose balance can be life threatening. Blood and urine tests can determine whether someone is diabetic or pre-diabetic. Diabetes is looming as a major public health concern; an estimated 25 million people in the U.S. have diabetes, with more than a quarter of them undiagnosed.
Video by TheVisualMD
How to Get Screened for Diabetes?
More than 37 million people in the United States have diabetes, and 1 in 5 of them don’t know they have it. About 96 million American adults have prediabetes, and more than 80% of them don’t know they have it. Why aren’t more people getting tested?
One reason is that prediabetes and type 2 diabetes often don’t have any symptoms (compared with type 1 diabetes symptoms, which can develop quickly and can be severe). That’s why people with any risk factors are urged to visit their doctor to get screened (getting tested when they don’t have any symptoms). Catching prediabetes early can help people prevent or delay type 2 diabetes, and finding out they have type 2 diabetes—and taking appropriate action—can help people prevent or delay serious health complications.
Getting tested is simple and quick. Your blood will be drawn at your doctor’s office or at a clinic so your blood sugar can be tested. Results are usually available quickly.
Screening is also available at some walk-in labs for a small fee. A word of caution: walk-in screenings often aren’t accurate because people haven’t fasted (not eaten) 8 to 10 hours before the test. Make sure you know how to prepare ahead of time.
Did You Know?
People covered by Medicare can get up to two free screenings a year if they have certain risk factors for diabetes, such as high blood pressure or obesity.
Source: Centers for Disease Control and Prevention (CDC)
Additional Materials (3)
Diabetes Risk Test
Could you have diabetes and not know it? About 1 in 5 Americans with diabetes has it and doesn’t know it. Take the American Diabetes Association Diabetes Risk Test to see if you are at risk for type 2 diabetes.
Document by NIDDK
ADA New Diabetes Screening Guidelines
Video by Armando Hasudungan/YouTube
Blood test that provides prior blood sugar average now recommended for diabetes screening, diagnosis
Video by UNC Health/YouTube
Diabetes Risk Test
NIDDK
6:15
ADA New Diabetes Screening Guidelines
Armando Hasudungan/YouTube
2:14
Blood test that provides prior blood sugar average now recommended for diabetes screening, diagnosis
UNC Health/YouTube
If You Don't Have a Doctor
What If You Don’t Have a Doctor?
You could have prediabetes for years without any clear symptoms. In fact, around 96 million American adults have prediabetes, but more than 80% of them don’t even know it. With prediabetes, blood sugar levels are higher than normal, but not high enough yet to be diagnosed as diabetes. Having prediabetes increases the risk for type 2 diabetes, heart disease, and stroke.
People who have any prediabetes risk factors are urged to talk to their doctor about getting their blood sugar tested. If you don’t have a doctor or are concerned about expense, there are free or low-cost options available as a first step:
Free screenings Free blood sugar testing is offered at some health fairs, community centers, and pharmacies.
Medicare coverage People covered by Medicare can get up to two free screenings a year if they have certain risk factors for diabetes, such as high blood pressure or obesity.
Low-cost health centers and labs Federally funded community health centers provide low-cost blood sugar testing on a sliding scale based on income. Testing is also available at some walk-in labs for a small fee.
A word of caution: Free blood sugar screenings often aren’t accurate because people haven’t fasted 8 to 10 hours before the test. Make sure you know how to prepare ahead of time.
One of the fastest ways to determine your risk: take the quiz at DoIHavePrediabetes.org. If your results show you’re likely to have prediabetes, it’s time to talk to a doctor about getting your blood sugar tested. A doctor can also connect you with the CDC-led National Diabetes Prevention Program to help you make lifestyle changes that can prevent or delay type 2 diabetes.
Source: Centers for Disease Control and Prevention (CDC)
A1C Test
Hemoglobin A1C Test
Also called: A1C test, HbA1c, Glycohemoglobin, Glycated hemoglobin, Glycosylated hemoglobin
A hemoglobin A1C test is a blood test that measures the amount of glucose (sugar) attached to hemoglobin. An A1C test can show your average glucose level for the past three months. Doctors may use the A1C alone or in combination with other diabetes tests to make a diagnosis. They also use the A1C to see how well you are managing your diabetes.
Hemoglobin A1C Test
Also called: A1C test, HbA1c, Glycohemoglobin, Glycated hemoglobin, Glycosylated hemoglobin
A hemoglobin A1C test is a blood test that measures the amount of glucose (sugar) attached to hemoglobin. An A1C test can show your average glucose level for the past three months. Doctors may use the A1C alone or in combination with other diabetes tests to make a diagnosis. They also use the A1C to see how well you are managing your diabetes.
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Use the slider below to see how your results affect your
health.
%{Hb}
5.7
6.5
Your result is Normal.
Normal results can slightly vary based on the laboratory and the method used.
Related conditions
A hemoglobin A1C (HbA1C) test is a blood test that shows what your average blood sugar (glucose) level was over the past two to three months.
Glucose is a type of sugar in your blood that comes from the foods you eat. Your cells use glucose for energy. A hormone called insulin helps glucose get into your cells. If you have diabetes your body doesn't make enough insulin, or your cells don't use it well. As a result, glucose can't get into your cells, so your blood sugar levels increase.
Glucose in your blood sticks to hemoglobin, a protein in your red blood cells. As your blood glucose levels increase, more of your hemoglobin will be coated with glucose. An A1C test measures the percentage of your red blood cells that have glucose-coated hemoglobin.
An A1C test can show your average glucose level for the past three months because:
Glucose sticks to hemoglobin for as long as the red blood cells are alive.
Red blood cells live about three months.
High A1C levels are a sign of high blood glucose from diabetes. Diabetes can cause serious health problems, including heart disease, kidney disease, and nerve damage. But with treatment and lifestyle changes, you can control your blood glucose levels.
An A1C test may be used to screen for or diagnose:
Type 2 diabetes. With type 2 diabetes your blood glucose gets too high because your body doesn't make enough insulin to move blood sugar from your bloodstream into your cells, or because your cells stop responding to insulin.
Prediabetes. Prediabetes means that your blood glucose levels are higher than normal, but not high enough to diagnosed as diabetes. Lifestyle changes, such as healthy eating and exercise, may help delay or prevent prediabetes from becoming type 2 diabetes.
If you have diabetes or prediabetes, an A1C test can help monitor your condition and check how well you've been able to control your blood sugar levels.
The Centers for Disease Control (CDC) recommends A1C testing for diabetes and prediabetes if:
You are over age 45.
If your results are normal, you should repeat the test every 3 years.
If your results show you have prediabetes, you will usually need to be tested every 1 to 2 years. Ask your provider how often to get tested and what you can do to reduce your risk of developing diabetes.
If your results show you have diabetes, you should get an A1C test at least twice a year to monitor your condition and treatment.
You are under 45 and are more likely to develop diabetes because you:
Have prediabetes.
Are overweight or have obesity.
Have a parent or sibling with type 2 diabetes.
Have high blood pressure or high cholesterol levels.
Have heart disease or have had a stroke.
Are physically active less than 3 times a week.
Have had gestational diabetes (diabetes during pregnancy) or given birth to a baby over 9 pounds.
Are African American, Hispanic or Latino, American Indian, or an Alaska Native person. Some Pacific Islander and Asian American people also have a higher risk of developing diabetes.
Have polycystic ovarian syndrome (PCOS).
You may also need an A1C test if you have symptoms of diabetes, such as:
Feeling very thirsty
Urinating (peeing) a lot
Losing weight without trying
Feeling very hungry
Blurred vision
Numb or tingling hands or feet
Fatigue
Dry skin
Sores that heal slowly
Having more infections than usual
A health care professional will take a blood sample from a vein in your arm, using a small needle. After the needle is inserted, a small amount of blood will be collected into a test tube or vial. You may feel a little sting when the needle goes in or out. This usually takes less than five minutes.
You don't need any special preparations for an A1C test.
There is very little risk to having a blood test. You may have slight pain or bruising at the spot where the needle was put in, but most symptoms go away quickly.
A1C results tell you what percentage of your hemoglobin is coated with glucose. The percent ranges are just a guide to what is normal. What's normal for you depends on your health, age, and other factors. Ask your provider what A1C percentage is healthy for you.
To diagnose diabetes or prediabetes, the percentages commonly used are:
Normal: A1C below 5.7%
Prediabetes: A1C between 5.7% and 6.4%
Diabetes: A1C of 6.5% or higher
Providers often use more than one test to diagnose diabetes. So, if your test result was higher than normal, you may have another A1C test or a different type of diabetes test, usually either a fasting blood glucose test or an oral glucose tolerance test (OGTT).
If your A1C test was done to monitor your diabetes, talk with your provider about what your test results mean.
The A1C test is not used to diagnose gestational diabetes or type 1 diabetes.
Also, if you have a condition that affects your red blood cells, such as anemia or another type of blood disorder, an A1C test may not be accurate for diagnosing diabetes. Kidney failure and liver disease can also affect A1C results. In these cases, your provider may recommend different tests to diagnose diabetes and prediabetes.
Hemoglobin A1C (HbA1c) Test: MedlinePlus Medical Test [accessed on Oct 05, 2022]
https://diabetesed.net/wp-content/uploads/2017/12/2018-ADA-Standards-of-Care.pdf [accessed on Apr 19, 2019]
https://labtestsonline.org/tests/hemoglobin-a1c [accessed on Apr 19, 2019]
https://www.niddk.nih.gov/health-information/diabetes/overview/tests-diagnosis/a1c-test [accessed on Apr 19, 2019]
Normal reference ranges can vary depending on the laboratory and the method used for testing. You must use the range supplied by the laboratory that performed your test to evaluate whether your results are "within normal limits."
Additional Materials (24)
Hemoglobin A1C molecule
Hemoglobin is a protein found inside red blood cells that carries oxygen from the lungs to cells throughout the body. Hemoglobin also binds with glucose. Diabetics have too much glucose in the bloodstream and this extra glucose binds (or glycates) with hemoglobin. Glycated hemoglobin usually stays glycated for the life of the red blood cell (about 3 months). Therefore, the percentage of hemoglobin that is glycated (measured as A1C) reflects glucose levels that have affected red blood cells up to 3 months in the past.
Image by TheVisualMD
Hemoglobin A1C: Red Blood Cells
Red blood cells use the iron-rich protein hemoglobin to carry oxygen from the lungs to cells throughout the body and return carbon dioxide to the lungs. The percentage of hemoglobin bound to blood glucose (hemoglobin A1C) is used to diagnose diabetes.
Image by TheVisualMD
Testing and Diagnosing Diabetes
Several tests are used to diagnose prediabetes and diabetes. In June 2009, the ADA, the European Association for the Study of Diabetes, and the International Diabetes Federation made a joint recommendation that type 2 diabetes testing include the glycated hemoglobin (A1C) test. This test measures average blood glucose level during the past 2-3 months by measuring the percentage of glucose attached to hemoglobin, the oxygen-carrying protein pigment in red blood cells.
Image by TheVisualMD
HemoglobinA1C molecule
The A1C test is a common blood test used to diagnose type 1 and type 2 diabetes and then to gauge how well you're managing your diabetes. The A1C test goes by many other names, including glycated hemoglobin, glycosylated hemoglobin, hemoglobin A1C and HbA1c. The A1C test result reflects your average blood sugar level for the past two to three months. Specifically, the A1C test measures what percentage of your hemoglobin, a protein in red blood cells that carries oxygen, is coated with sugar (glycated). The higher your A1C level, the poorer your blood sugar control. And if you have previously diagnosed diabetes, the higher the A1C level, the higher your risk of diabetes complications.
Image by TheVisualMD
α,β-hemoglobin/haptoglobin hexamer complex
A model of α,β-hemoglobin/haptoglobin hexamer complex. There are 2 α,β-hemoglobin dimers depicted: one space filling model (yellow/orange), and one ribbon model (purple/blue). Each is bound by a haptoglobin molecule (both haptoglobin molecules are shown in pink, with one as a space filling model and one as a ribbon model).
Image by Ayacop
Hemoglobin, Carbon Monoxide
Hemoglobin is an iron-containing protein that enables red blood cells to deliver oxygen from the lungs to cells throughout the body. But the same binding site on the hemoglobin molecule has an even stronger affinity for carbon monoxide, which is why we are so susceptible to poisoning by this deadly gas; carbon monoxide grabs all the binding sites and starves the body's tissues of oxygen
Image by TheVisualMD
This browser does not support the video element.
Hemoglobin A1c
The hemoglobin A1c test measures the percentage of hemoglobin bound to blood sugar (glucose); the test is used to diagnose type 1 and type 2 diabetes. Because the test results reflect average blood sugar levels over a period of 2-3 months (rather than daily fluctuations), the hemoglobin A1C test is also used to gauge how well patients are managing their diabetes over time.
Video by TheVisualMD
Understanding Your A1C (Conditions A-Z)
Video by Healthguru/YouTube
Haemoglobin
Video by Wellcome Trust/YouTube
A1c - What You Need To Know
Video by Rehealthify/YouTube
This browser does not support the video element.
Type 2 Diabetes Testing
An estimated 79 million Americans, just over 25 percent of the population aged 20 years or older, have prediabetes. Prediabetes is a state where blood sugars may be a little bit elevated, but are not yet elevated to a dangerous range. It is typically asymptomatic, and if undiagnosed and untreated, prediabetes may lead to a potentially life-threatening condition called type 2 diabetes. Complications of type 2 diabetes include blindness, heart attack, and stroke. Prediabetes is readily detectable through simple blood testing with a goal of detecting abnormal glucose levels. Two common and complementary tests include fasting blood sugar and hemoglobin A1C (HbA1c) tests. With early detection and diagnosis, appropriate and immediate action can be made by the patient to reduce complications and to ensure a long and healthy life.
Video by TheVisualMD
Diagnosis of Type 2 Diabetes
Video by Animated Diabetes Patient/YouTube
Hemoglobin A1c & Diabetes
Video by DiabeTV/YouTube
Diabetic HbA1c - Everything You Need To Know - Dr. Nabil Ebraheim
Video by nabil ebraheim/YouTube
What Is An A1C?
Video by dLife/YouTube
A1C Levels
Video by Khan Academy/YouTube
This browser does not support the video element.
Type 1 Diabetes Diagnosis & Treatment
Type 1 diabetes can be diagnosed with blood tests that measure how much sugar is in your blood. They include: hemoglobin A1C, fasting blood glucose, and oral glucose tolerance. Type 1 diabetes is usually diagnosed in childhood or adolescence. About 5% of adults with diabetes have type 1 diabetes. Early diagnosis is crucial for early treatment. Type 1 diabetics need to take insulin, either through a pump or injections. Regular exercise as well as a diet low in refined carbohydrates will also help control blood sugar levels. By maintaining appropriate blood sugar levels, type 1 diabetics can lead normal lives free of serious complications.
Video by TheVisualMD
The 411 On Your A1c
Video by Lee Health/YouTube
Is Your A1C AOK?
Video by Lee Health/YouTube
What if the root cause of type 2 diabetes is found in the gut rather than the pancreas?
Video by TEDMED/YouTube
Lactate Threshold Test
Video by Mount Sinai Health System/YouTube
How HbA1c testing detects glucose in your body for diabetes type 2
Video by Pathology Tests Explained/YouTube
A Critical Balance
Key Players
The Fuel Supply Chain
Diabetes Symptoms
Overweight
Diabetes and Large Vessel Disease
Diabetes and Small Vessel Disease
Nerve Damage
Testing and Diagnosis
Keep It Down
Health in Action
Put Out the Fire
Calming Diabetes
Keeping Tabs on Glucose
1
2
3
4
5
6
7
8
9
10
11
12
13
14
Diabetes in the US
Interactive by TheVisualMD
Hemoglobin A1C molecule
TheVisualMD
Hemoglobin A1C: Red Blood Cells
TheVisualMD
Testing and Diagnosing Diabetes
TheVisualMD
HemoglobinA1C molecule
TheVisualMD
α,β-hemoglobin/haptoglobin hexamer complex
Ayacop
Hemoglobin, Carbon Monoxide
TheVisualMD
0:27
Hemoglobin A1c
TheVisualMD
1:10
Understanding Your A1C (Conditions A-Z)
Healthguru/YouTube
5:31
Haemoglobin
Wellcome Trust/YouTube
1:28
A1c - What You Need To Know
Rehealthify/YouTube
5:52
Type 2 Diabetes Testing
TheVisualMD
4:31
Diagnosis of Type 2 Diabetes
Animated Diabetes Patient/YouTube
1:43
Hemoglobin A1c & Diabetes
DiabeTV/YouTube
4:41
Diabetic HbA1c - Everything You Need To Know - Dr. Nabil Ebraheim
nabil ebraheim/YouTube
3:03
What Is An A1C?
dLife/YouTube
6:09
A1C Levels
Khan Academy/YouTube
1:12
Type 1 Diabetes Diagnosis & Treatment
TheVisualMD
1:56
The 411 On Your A1c
Lee Health/YouTube
1:41
Is Your A1C AOK?
Lee Health/YouTube
3:21
What if the root cause of type 2 diabetes is found in the gut rather than the pancreas?
TEDMED/YouTube
1:06
Lactate Threshold Test
Mount Sinai Health System/YouTube
2:28
How HbA1c testing detects glucose in your body for diabetes type 2
Pathology Tests Explained/YouTube
Diabetes in the US
TheVisualMD
Glucose Tolerance Test
Glucose Tolerance Test
Also called: Oral Glucose Tolerance Test, OGTT
The oral glucose tolerance test consists of a series of steps that involve drinking a load of 75 grams of glucose (sugar). This test is commonly used to diagnose type 1 and type 2 diabetes as well as gestational diabetes.
Glucose Tolerance Test
Also called: Oral Glucose Tolerance Test, OGTT
The oral glucose tolerance test consists of a series of steps that involve drinking a load of 75 grams of glucose (sugar). This test is commonly used to diagnose type 1 and type 2 diabetes as well as gestational diabetes.
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Use the slider below to see how your results affect your
health.
mg/dL
140
200
Your result is Normal.
Normal results vary based on the laboratory and the method used.
Related conditions
An oral glucose tolerance test measures how well your body is able to absorb glucose (sugar) from your regular diet.
Your doctor may want to order this test to diagnose prediabetes, type 1 diabetes, and type 2 diabetes in the following situations:
If you have symptoms of diabetes, such as polyuria (frequent urination), polydipsia (excessive thirst), and polyphagia (excessive hungriness).
For all people older than 45-years-old, despite not having any symptoms.
If you are younger than 45-years-old and don’t have any symptoms of diabetes but are overweight or obese and have one or more risk factors, which includes:
Having a close relative with diabetes.
Hypertension (high blood pressure).
History of cardiovascular diseases, such as stroke.
High triglyceride levels.
Low levels of HDL cholesterol, also known as “good cholesterol.”
Physical inactivity
Polycystic ovary syndrome in women.
To diagnose gestational diabetes (onset of diabetes during pregnancy).
While fasting, a small amount of blood will be drawn of a vein in your arm by using a needle. Then, you will drink a glass of a syrupy solution that contains 75 grams of glucose (sugar).
You will be asked to wait for up to 3 hours while the health-care provider draws another blood sample at the one-hour, two-hour, or sometimes 3-hour mark.
Do not change your eating habits the days prior to the test. You must be fasting for at least 8 to 12 hours before the test is done; only water is allowed. Follow the instructions provided by your healthcare practitioner.
The risks are mostly related to the blood extraction procedure, including a little bleeding, temporary pain or discomfort, bruising, or local infection.
Some people may find the glucose drink to be overly sweet and difficult to tolerate. You may experience nausea, stomach discomfort, and diarrhea.
Two-hour oral glucose tolerance test (OGTT) reference ranges are:
Less than 140 mg/dL (or 7.8 mmol/L): normal.
From 140 to 199 mg/dL (or from 7.8 to 11.1 mmol/L): prediabetes. This means that your blood glucose levels (glycemia) is too high to be considered normal but still doesn’t met the criteria for diabetes.
Greater or equal than 200 mg/dL (or 11.1 mmol/L) on more than one testing occasion: diabetes.
Usually, when the first two-hour OGTT result is greater or equal than 200 mg/dL, and in the absence of symptoms of hyperglycemia (high blood sugar), a second test must be performed to confirm the diabetes diagnosis.
LabCorp: Glucose Tolerance Test (GTT), Two-hour (Oral WHO Protocol) [accessed on Sep 01, 2018]
https://diabetesed.net/wp-content/uploads/2017/12/2018-ADA-Standards-of-Care.pdf [accessed on Oct 17, 2018]
Glucose Tolerance Test: Purpose, Procedure, and Risks [accessed on Oct 17, 2018]
Glucose tolerance test - Mayo Clinic [accessed on Oct 17, 2018]
RACGP - Oral glucose tolerance testing [accessed on Oct 17, 2018]
Glucose tolerance test - non-pregnant: MedlinePlus Medical Encyclopedia [accessed on Oct 17, 2018]
Glucose Tests [accessed on Oct 17, 2018]
Normal reference ranges can vary depending on the laboratory and the method used for testing. You must use the range supplied by the laboratory that performed your test to evaluate whether your results are "within normal limits."
Additional Materials (16)
Oral Glucose Tolerance Test
The glucose tolerance test is a lab test to check how your body breaks down sugar. The most common glucose tolerance test is the oral glucose tolerance test (OGTT).
Image by TheVisualMD
Insulin and Glucose Vessel Dispersion
Our bodies and brains run on glucose. Our ability to use glucose as a source of energy depends on the hormone insulin, produced by the pancreas. Levels of insulin and glucose in the blood must be maintained in careful balance. Chronic conditions of too much or too little glucose in the bloodstream can damage the heart, kidneys, eyes, nerves, and blood vessels.
Image by TheVisualMD
Random glucose (pink) in a capillary
This image depicts a healthy capillary. Capillaries, the smallest blood vessels in your body, are where nutrients are transferred from blood to cells, and waste from cells to blood. The body's cells depend on sugar in the blood, which is derived from carbohydrates, for food and energy. Allowing for the innumerable differences among individuals, the threshold for a normal blood-sugar (glucose, pink) level in healthy people is 100 mg/dL; that is, 100 milligrams of glucose per deciliter of blood. Lower-than-normal levels characterize hypoglycemia and higher than normal levels characterize hyperglycemia. Without insulin (yellow), glucose is not able to enter cells to be used as fuel. Because of this, healthy insulin levels are a key factor in keeping blood glucose levels normal.
Image by TheVisualMD
Testing and Diagnosing Diabetes
Several tests are used to diagnose prediabetes and diabetes. In June 2009, the ADA, the European Association for the Study of Diabetes, and the International Diabetes Federation made a joint recommendation that type 2 diabetes testing include the glycated hemoglobin (A1C) test. This test measures average blood glucose level during the past 2-3 months by measuring the percentage of glucose attached to hemoglobin, the oxygen-carrying protein pigment in red blood cells.
Image by TheVisualMD
This browser does not support the video element.
Glucose tolerance test
Oral Glucose Tolerance Test : The glucose tolerance test is a lab test to check how your body breaks down sugar. The most common glucose tolerance test is the oral glucose tolerance test (OGTT).
Video by TheVisualMD
This browser does not support the video element.
Blood Glucose and Baselining Your Health
Our bodies and brains run on glucose, a simple sugar produced by the digestion of carbohydrates. The body's ability to use glucose depends on the hormone insulin, which is produced by the pancreas. Blood sugar levels naturally rise after meals, but insulin from a healthy pancreas keeps these levels within a narrow range. In diabetes, however, this balance is disrupted because either the body loses its ability to respond to insulin or the pancreas loses its ability to produce insulin. Too much or too little glucose in the bloodstream can damage blood vessels in the kidneys and eyes, as well as nerve cells; acute disruptions of the insulin/glucose balance can be life threatening. Blood and urine tests can determine whether someone is diabetic or pre-diabetic. Diabetes is looming as a major public health concern; an estimated 25 million people in the U.S. have diabetes, with more than a quarter of them undiagnosed.
Video by TheVisualMD
This browser does not support the video element.
Fasting Plasma Glucose
The fasting plasma glucose (FPG) test, also known as the fasting blood sugar test, measures blood sugar levels and is used to diagnose diabetes.
Video by TheVisualMD
This browser does not support the video element.
Type 1 Diabetes Diagnosis & Treatment
Type 1 diabetes can be diagnosed with blood tests that measure how much sugar is in your blood. They include: hemoglobin A1C, fasting blood glucose, and oral glucose tolerance. Type 1 diabetes is usually diagnosed in childhood or adolescence. About 5% of adults with diabetes have type 1 diabetes. Early diagnosis is crucial for early treatment. Type 1 diabetics need to take insulin, either through a pump or injections. Regular exercise as well as a diet low in refined carbohydrates will also help control blood sugar levels. By maintaining appropriate blood sugar levels, type 1 diabetics can lead normal lives free of serious complications.
Video by TheVisualMD
This browser does not support the video element.
What Is Type 2 Diabetes?
Go deep inside your body to see how type 2 diabetes happens, what it does to your body-and what you can do about it. Diabetes expert Dr. David Katz of the Yale Prevention Research Center talks about the frightening future of diabetes: in just a few decades, one third of all Americans may have diabetes. See the pancreas, where insulin is produced. Real imaging data reveals the body's inner anatomy slice by slice, from brain to base of spine. Dr. Cynthia Geyer of Canyon Ranch talks about how insulin resistance develops. View its results, as visceral abdominal fat builds up and chokes the vital organs. Discover the symptoms of type 2 diabetes and find out if you should be tested. See the complications of diabetes, including cardiovascular disease, hypertension, vision damage, kidney disease, and gangrene. The good news? Diabetes is a highly manageable disease. Dr. Mark Liponis of Canyon Ranch talks about controlling your risk for type 2 diabetes and, by managing it, reversing its symptoms and literally slowing the aging process.
Video by TheVisualMD
This browser does not support the video element.
Exercise & Diabetes
The body is powered by glucose, commonly called blood sugar, which it converts to fuel. In diabetics, the system of signaling the cells to take up glucose from the blood is impaired, disrupting this vital chain of events. Researchers have found that exercise helps diabetics' insulin sensitivity, meaning that their bodies are better able to gather up this glucose for energy. In fact, those who exercise at least 5 days a week and improve their diet improved their health more than diabetics who took medication only.
Video by TheVisualMD
This browser does not support the video element.
Managing Diabetes
The first step in managing type 2 diabetes is accepting the fact that you have diabetes. Diabetics need to take an active role in managing their condition. Regular doctor visits are a must to check on blood pressure and cholesterol levels and to monitor eye health. Dr. Michael Stein of Brown University talks about stabilizing kidney function. Blood sugar levels need to be monitored using self-testing kits. According to Dr. Osama Hamdy of the Joslin Diabetes Center, the best treatments for type 2 diabetes are diet and exercise, not medications. Cynthia Geyer of Canyon Ranch explains how exercise enables tissues to take up glucose independent of insulin receptors. Eating small sensible meals helps to keep blood sugar levels and weight under control. Losing 7% of body weight can increase insulin sensitivity by 50%--that's equivalent to two diabetes medications at maximum dose. Dr. Mark Liponis of Canyon Ranch tells us the good news about diabetes: we have the ability to improve diabetes, and that isn't true of many conditions.
Video by TheVisualMD
This browser does not support the video element.
Blood glucose monitoring
Self Test Blood Glucose Level : Unlike many other diseases, type 2 diabetes is treatable, and its symptoms can be reduced or even eliminated. The key is monitoring your blood sugar level by self-testing. When you keep your glucose level down, you can prevent serious health consequences and health care costs: For every 1% reduction in HbA1C levels, there is a 30% reduction in complications such as eye disease and nerve damage, and a 16% drop in complications such as heart disease.
Video by TheVisualMD
Oral Glucose Tolerance Test Infomercial
Video by Dokie PH/YouTube
Diagnosis of Type 2 Diabetes
Video by Animated Diabetes Patient/YouTube
A Critical Balance
Key Players
The Fuel Supply Chain
Diabetes Symptoms
Overweight
Diabetes and Large Vessel Disease
Diabetes and Small Vessel Disease
Nerve Damage
Testing and Diagnosis
Keep It Down
Health in Action
Put Out the Fire
Calming Diabetes
Keeping Tabs on Glucose
1
2
3
4
5
6
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9
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11
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14
Diabetes in the US
Interactive by TheVisualMD
Healthy Capillary Blood Vessel
Cross-section of Healthy Capillary Blood Vessel with Normal Glucose and Insulin Levels
Cross-Section of Damaged Capillary Blood Vessel with Very High Glucose and Insulin Levels
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Healthy Capillary Blood Vessel and and Damaged Capillary Blood Vessel Caused by High Levels of Blood Glucose
1) Healthy Capillary Blood Vessel - This image depicts a healthy capillary. Capillaries are the smallest blood vessels in your body. They can be so thin in diameter that blood cells have to bend in order to pass through. Capillaries are where the transfer of nutrients from the blood to cells, and the transfer of waste from cells to blood, takes place. In a healthy body, the blood vessels are smooth and elastic.
2) Cross-Section of Healthy Capillary Blood Vessel with Normal Glucose and Insulin Levels - This image depicts a healthy capillary. The body's cells depend on sugar in the blood, which is derived from carbohydrates, for food and energy. Allowing for the innumerable differences among individuals, the threshold for a normal blood sugar (glucose, pink) level in healthy people is 100 mg/dL; that is, 100 milligrams of glucose per deciliter of blood. Lower-than-normal levels characterize hypoglycemia and higher-than-normal levels characterize hyperglycemia. Without insulin (yellow), glucose is not able to enter cells to be used as fuel. Because of this, healthy insulin levels are a key factor in keeping blood glucose levels normal.
3) Cross-Section of Damaged Capillary Blood Vessel with Very High Glucose and Insulin Levels - This image depicts an unhealthy, damaged capillary with very high levels of insulin and glucose. Higher than normal levels of blood glucose lead to hyperglycemia. Hyperglycemia is the hallmark of prediabetes (between 100 and 125 mg/dL) and diabetes (126 mg/dL and higher). It is caused by either too little insulin being released by the pancreas or the body's inability to use insulin properly. Hyperglycemia leads to microangiopathy, marked by endothelial cell apoptosis (programmed cell death), accumulation of AGEs (advanced glycation end products), and thickening of the basement membrane, which can lead to the development of lesions, vasoconstriction, and altered vessel function
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Random Blood Sugar Test
Blood Glucose Test
Also called: Blood Sugar Level, Glucose Test, Random Plasma Glucose, Random Glucose, Random Blood Glucose (RPG)
A blood glucose test measures the amount of glucose (sugar) in your blood. It may be used to help diagnose or monitor diabetes. The test can involve a finger prick or a blood draw from your vein.
Blood Glucose Test
Also called: Blood Sugar Level, Glucose Test, Random Plasma Glucose, Random Glucose, Random Blood Glucose (RPG)
A blood glucose test measures the amount of glucose (sugar) in your blood. It may be used to help diagnose or monitor diabetes. The test can involve a finger prick or a blood draw from your vein.
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Use the slider below to see how your results affect your
health.
mg/dL
70
100
125
Your result is Normal.
A healthy (normal) fasting blood glucose level for someone without diabetes is 70 to 99 mg/dL (3.9 to 5.5 mmol/L). Values between 50 and 70 mg/dL (2.8 to 3.9 mmol/L) for people without diabetes can be "normal" too.
Related conditions
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Use the slider below to see how your results affect your
health.
mg/dL
80
140
200
Your result is Normal.
In a random blood glucose test, a normal result depends on when you last ate. You may start your day at below 100 mg/dL in the morning before breakfast and your blood glucose may rise as high as 140 mg/dL about 2 hours after meals during the day. Most of the time, the blood glucose level will be below 125 mg/dL (6.9 mmol/L).
Related conditions
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Use the slider below to see how your results affect your
health.
mg/dL
140
Your result is Normal.
Within 2 hours of eating, your insulin and blood glucose levels should return to normal. Normal blood glucose values in people who don't have diabetes are less than 140 mg/dL, and in people with diabetes are less than 180 mg/dL.
Related conditions
A blood glucose test measures the glucose levels in your blood. Glucose is a type of sugar. It is your body's main source of energy. A hormone called insulin helps move glucose from your bloodstream into your cells.
Too much or too little glucose in the blood can be a sign of a serious medical condition. High blood glucose levels (hyperglycemia) may be a sign of diabetes, a disorder that can cause serious, long-term health conditions.
High blood sugar may also be caused by other conditions that can affect insulin or glucose levels in your blood, such as problems with your pancreas or adrenal glands.
Low blood glucose levels (hypoglycemia) are common among people with type 1 diabetes and people with type 2 diabetes who take certain diabetes medicines. Certain conditions, such as liver disease, may cause low levels of blood glucose in people without diabetes, but this is uncommon. Without treatment, severe low blood sugar can lead to major health problems, including seizures and brain damage.
Other names: blood sugar, self-monitoring of blood glucose (SMBG), fasting plasma glucose (FPG), fasting blood sugar (FBS), fasting blood glucose (FBG), random blood sugar, glucose challenge test, oral glucose tolerance test (OGTT)
A blood glucose test is used to find out if your blood sugar levels are in a healthy range. It is often used to help diagnose and monitor diabetes.
Your health care provider may order a blood glucose test if you have symptoms of high glucose levels or low glucose levels.
Symptoms of high blood glucose levels include:
Increased thirst and urination (peeing)
Blurred vision
Fatigue
Sores that don't heal
Weight loss when you're not trying to lose weight
Numbness or tingling in your feet or hands
Symptoms of low blood glucose levels include:
Feeling shaky or jittery
Hunger
Fatigue
Feeling dizzy, confused, or irritable
Headache
A fast heartbeat or arrhythmia (a problem with the rate or rhythm of your heartbeat)
Having trouble seeing or speaking clearly
Fainting or seizures
You may also need a blood glucose test if you have a high risk for developing type 2 diabetes. You're more likely to develop diabetes if you:
Are overweight or have obesity
Are age 45 or older
Have a family history of diabetes
Have high blood pressure
Don't exercise enough
Have a history of heart disease or stroke
Have had gestational diabetes (diabetes that happens only during pregnancy)
If you are pregnant, you will likely get a blood glucose test between the 24th and 28th week of your pregnancy to check for gestational diabetes.
A health care professional will take a blood sample from a vein in your arm, using a small needle. After the needle is inserted, a small amount of blood will be collected into a test tube or vial. You may feel a little sting when the needle goes in or out.
For some types of glucose blood tests, you will drink a sugary liquid and wait for an hour before your blood sample is taken:
A glucose challenge test is used to test for gestational diabetes in pregnancy. If your blood glucose level is higher than normal, you may have gestational diabetes. You'll need an oral glucose tolerance test (OGTT) to get a diagnosis.
An oral glucose tolerance test (OGTT) is used to diagnose gestational diabetes, and type 2 diabetes and prediabetes in people who aren't pregnant. A blood sample will be taken before you have a sugary drink and then again, every hour for the next 2 or 3 hours.
If your provider orders a fasting blood glucose test or an oral glucose tolerance test, you will need to fast (not eat or drink) for at least eight hours before the test. Other blood glucose tests don't require any special preparations. Ask your provider whether you need to fast before your glucose test.
There is very little risk to having a blood test. You may have slight pain or bruising at the spot where the needle was put in, but most symptoms go away quickly. After an oral glucose tolerance test, you may feel light-headed. Your provider may suggest that you plan to have someone take you home.
If your results show higher than normal glucose levels, it may mean you have or are at risk for getting diabetes. High glucose levels may also be a sign of:
Hyperthyroidism
Pancreas disorders
Stress from surgery, very serious illness, or trauma
If you have diabetes, lower than normal glucose levels may be caused by:
Side effects from certain diabetes medicines
Not eating enough, especially after taking diabetes medicine
Being more physically active than usual
If you don't have diabetes, low blood glucose levels may be a sign of:
Liver disease
Kidney disease
Underactive adrenal, pituitary, or thyroid gland (hypothyroidism)
Alcohol use disorder (AUD)
If your glucose results are not normal, it doesn't always mean you have a medical condition that needs treatment. Certain medicines and stress can affect glucose levels. To learn what your test results mean, talk with your health care provider.
If you have diabetes, you may need to do blood sugar testing at home every day to help manage your blood glucose levels. There are two ways to do this:
Blood glucose meters require you to prick your finger with a small device called a lancet. You apply a drop of blood to a test strip and insert it into a small, electronic glucose meter, which measures the glucose is in your blood.
Continuous glucose monitors (CGM) use a tiny sensor that you insert under your skin. Every few minutes, the sensor measures glucose levels in fluids between your cells. If your glucose is too high or too low, you use a blood glucose meter to check your blood levels before making changes to raise or lower your glucose level.
Blood sugar test: Health Article | MedlinePlus - NIH [accessed on Sep 07, 2018]
Random glucose test - Wikipedia [accessed on Sep 07, 2018]
001032: Glucose | LabCorp [accessed on Sep 07, 2018]
001818: Glucose, Plasma | LabCorp [accessed on Sep 07, 2018]
Glucose (Blood) - Health Encyclopedia - University of Rochester Medical Center [accessed on Sep 07, 2018]
Blood Glucose Test: MedlinePlus Medical Test [accessed on Dec 12, 2022]
Normal reference ranges can vary depending on the laboratory and the method used for testing. You must use the range supplied by the laboratory that performed your test to evaluate whether your results are "within normal limits."
Additional Materials (12)
Glucose: Pancreas
The pancreas is a large gland (located behind the stomach) that secretes digestive enzymes into the duodenum (small intestine), which then combine with bile, produced in the liver. The pancreas also produces the hormone insulin, which helps control blood sugar levels.
Image by TheVisualMD
Glucose: Neurons (Utilize Glucose)
Our brains need a continuous supply of fuel in the form of glucose because they can't store energy as fat or glycogen. Though the brain represents only about 2% of the body's mass, it consumes 60% of the sugar coursing through our bloodstreams.
Image by TheVisualMD
Glucose: Insulin & Glucose
The body's ability to use glucose depends on the hormone insulin, produced by the pancreas. Blood levels of glucose rise after meals, but insulin keeps glucose levels within a narrow range; excess glucose is stored in the liver as glycogen.
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Molecular structure of glucose | Macromolecules | Biology | Khan Academy
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Glucose Insulin and Diabetes
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How do carbohydrates impact your health? - Richard J. Wood
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Diabetes and insulin injection
There are 3 main types of diabetes. Type 1 diabetes develops when the body's immune system destroys the pancreatic cells that produce the hormone insulin. Type 2 diabetes develops when cells can no longer use insulin effectively, which can result in the pancreas gradually losing its ability to produce insulin. Both types of diabetes can require insulin injections to compensate for this deficiency. A third type, gestational diabetes, is a form of glucose intolerance that appears in some women during pregnancy.
Image by TheVisualMD
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Blood Glucose and Baselining Your Health
Our bodies and brains run on glucose, a simple sugar produced by the digestion of carbohydrates. The body's ability to use glucose depends on the hormone insulin, which is produced by the pancreas. Blood sugar levels naturally rise after meals, but insulin from a healthy pancreas keeps these levels within a narrow range. In diabetes, however, this balance is disrupted because either the body loses its ability to respond to insulin or the pancreas loses its ability to produce insulin. Too much or too little glucose in the bloodstream can damage blood vessels in the kidneys and eyes, as well as nerve cells; acute disruptions of the insulin/glucose balance can be life threatening. Blood and urine tests can determine whether someone is diabetic or pre-diabetic. Diabetes is looming as a major public health concern; an estimated 25 million people in the U.S. have diabetes, with more than a quarter of them undiagnosed.
Video by TheVisualMD
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Fasting Plasma Glucose
The fasting plasma glucose (FPG) test, also known as the fasting blood sugar test, measures blood sugar levels and is used to diagnose diabetes.
Video by TheVisualMD
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What Is Type 2 Diabetes?
Go deep inside your body to see how type 2 diabetes happens, what it does to your body-and what you can do about it. Diabetes expert Dr. David Katz of the Yale Prevention Research Center talks about the frightening future of diabetes: in just a few decades, one third of all Americans may have diabetes. See the pancreas, where insulin is produced. Real imaging data reveals the body's inner anatomy slice by slice, from brain to base of spine. Dr. Cynthia Geyer of Canyon Ranch talks about how insulin resistance develops. View its results, as visceral abdominal fat builds up and chokes the vital organs. Discover the symptoms of type 2 diabetes and find out if you should be tested. See the complications of diabetes, including cardiovascular disease, hypertension, vision damage, kidney disease, and gangrene. The good news? Diabetes is a highly manageable disease. Dr. Mark Liponis of Canyon Ranch talks about controlling your risk for type 2 diabetes and, by managing it, reversing its symptoms and literally slowing the aging process.
Video by TheVisualMD
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What are Carbohydrates?
Most of the foods we consume, including fruits and vegetables, contain carbohydrates. Once metabolized, these macronutrients become the body's primary source of energy, providing food to cells. And while nature never produced any "good" or "bad" carbs, it's also true that excessive carbohydrate consumption can lead to unwanted weight gain. Before you strike carbs from your diet, though, learn more about how this important nutrient supports your good health.
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Simple Carbohydrates
Because only the smallest molecules of sugar can pass through the intestinal walls and into the blood stream, foods ingested as simple carbohydrates (single- and double-molecule sugars) can be used immediately while complex carbohydrates (three or more molecules) require more time and action to break down and be absorbed. Some simple sugars occur naturally in vegetables, milk, honey, and other unprocessed foods. Synthetic sweeteners such as corn syrup and high fructose are simple sugars as well. Simple carbs cause a rapid rise and fall in glucose, leaving you feeling hungry faster.
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Glucose: Neurons (Utilize Glucose)
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Glucose: Insulin & Glucose
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9:19
Molecular structure of glucose | Macromolecules | Biology | Khan Academy
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7:24
Glucose Insulin and Diabetes
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How do carbohydrates impact your health? - Richard J. Wood
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Diabetes and insulin injection
TheVisualMD
1:36
Blood Glucose and Baselining Your Health
TheVisualMD
0:23
Fasting Plasma Glucose
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4:22
What Is Type 2 Diabetes?
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1:11
What are Carbohydrates?
TheVisualMD
1:09
Simple Carbohydrates
TheVisualMD
Glucose Challenge Test
Glucose Challenge Test
Also called: GCT, Gestational Diabetes Screen
The glucose challenge test comprises a series of steps which involve drinking a load of glucose (sugar) to see how the body reacts to it. This test is commonly used to diagnose gestational diabetes in pregnant women without a preexisting diabetes diagnosis.
Glucose Challenge Test
Also called: GCT, Gestational Diabetes Screen
The glucose challenge test comprises a series of steps which involve drinking a load of glucose (sugar) to see how the body reacts to it. This test is commonly used to diagnose gestational diabetes in pregnant women without a preexisting diabetes diagnosis.
A glucose challenge test measures how well your body is able to absorb glucose (sugar) from your regular diet.
Your doctor may want to order this test to diagnose gestational diabetes mellitus (GDM).
GDM is diabetes that is diagnosed in previously healthy women during their second or third trimester of pregnancy. Usually, this test is performed during the weeks 24-28 of gestation.
While fasting, a small amount of blood will be drawn of a vein in your arm by using a needle. Then, you will drink a glass of a syrupy solution that contains glucose (sugar).
You will be asked to wait for up to 3 hours while the health-care provider draws another blood sample at the one-hour, two-hour, or sometimes 3-hour mark.
Do not change your eating habits the days prior to the test. You may be asked to fast for at least 8 to 12 hours before the test is done. Follow the instructions provided by your healthcare practitioner.
The risks are mostly related to the blood extraction procedure, including a little bleeding, temporary pain or discomfort, bruising, or local infection.
Some people may find the glucose drink to be overly sweet and difficult to tolerate. You may experience nausea, stomach discomfort, and diarrhea.
In pregnant women GDM diagnosis can be accomplished with either of two strategies:
One-step strategy:
After drinking a syrupy solution containing 75 grams of glucose, your blood glucose levels will be measured at 1 and 2 hours. You must be fasting prior to this test.
The one-step glucose challenge reference ranges and are as follows:
Fasting blood glucose: normal values are considered to be less than 92 mg/dL (5.1 mmol/L).
1 hour after oral glucose intake: normal values are less than 180 mg/dL (10.0 mmol/L).
2 hours after oral glucose intake: normal values are less than 153 mg/dL (8.5 mmol/L).
When any of these values are exceeded in pregnant women, the diagnosis of gestational diabetes is made.
Two-step strategy:
Step 1
After drinking a syrupy solution containing 50 grams of glucose, your blood glucose levels will be measured after 1 hour. You don’t need to be fasting prior to this test.
If your blood glucose levels exceed 130 mg/dL (7.2 mmol/L), the second step must be performed.
Step 2
After drinking a syrupy solution containing 100 grams of glucose, your blood glucose levels will be measured at 1, 2, and 3 hours. You must be fasting prior to this test.
Fasting blood glucose: normal values are considered to be less than 95 mg/dL (5.3 mmol/L).
1 hour after oral glucose intake: normal values are less than 180 mg/dL (10.0 mmol/L).
2 hours after oral glucose intake: normal values are less than 155 mg/dL (8.6 mmol/L).
3 hours after oral glucose intake: normal values are less than 140 mg/dL (7.8 mmol/L).
When at least one (in some cases two) of these values are exceeded in pregnant women, the diagnosis of gestational diabetes is made.
Women diagnosed with diabetes in their first trimester of pregnancy should be classified as having preexisting diabetes, not gestational diabetes.
https://diabetesed.net/wp-content/uploads/2017/12/2018-ADA-Standards-of-Care.pdf [accessed on Oct 22, 2018]
102277: Gestational Diabetes Screen (ACOG Recommendations) | LabCorp [accessed on Oct 02, 2018]
Glucose challenge test - Mayo Clinic [accessed on Oct 22, 2018]
50 Grams Oral Glucose Challenge Test: Is It an Effective Screening Test for Gestational Diabetes Mellitus? [accessed on Oct 22, 2018]
Additional Materials (3)
Baby Development in the Womb
Baby Development in the Womb
Image by TheVisualMD
Glucose Challenge Test during Pregnancy | 1mg Lab Test
Video by Tata 1mg/YouTube
I get a glucose test at my 26 week checkup. What can I eat, and when should I stop eating?
Video by IntermountainMoms/YouTube
Baby Development in the Womb
TheVisualMD
1:47
Glucose Challenge Test during Pregnancy | 1mg Lab Test
Tata 1mg/YouTube
1:13
I get a glucose test at my 26 week checkup. What can I eat, and when should I stop eating?
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Diabetes Mellitus
Diabetes is a chronic disease in which your blood sugar levels are too high. Over time, having too much sugar in your blood can cause serious problems. There are three main types of diabetes: type 1, type 2, and gestational diabetes (diabetes while pregnant). Learn more about the three main types of diabetes and how to get tested.