This page lists cancer drugs approved by the Food and Drug Administration (FDA) for breast cancer. The list includes generic and brand names. This page also lists common drug combinations used in breast cancer. The individual drugs in the combinations are FDA-approved. However, the drug combinations themselves usually are not approved, although they are widely used.

Drugs Approved to Prevent Breast Cancer

• Evista (Raloxifene Hydrochloride)
• Raloxifene Hydrochloride
• Soltamox (Tamoxifen Citrate)
• Tamoxifen Citrate

Drugs Approved to Treat Breast Cancer

• Abemaciclib
• Abraxane (Paclitaxel Albumin-stabilized Nanoparticle Formulation)
• Ado-Trastuzumab Emtansine
• Afinitor (Everolimus)
  Afinitor Disperz (Everolimus)
• Alpelisib
• Anastrozole
• Aredia (Pamidronate Disodium)
• Arimidex (Anastrozole)
• Aromasin (Exemestane)
• Capecitabine
• Cyclophosphamide
• Docetaxel
• Doxorubicin Hydrochloride
• Elacestrant Dihydrochloride
• Ellence (Epirubicin Hydrochloride)
• Enhertu (Fam-Trastuzumab Deruxtecan-nxki)
• Epirubicin Hydrochloride
• Eribulin Mesylate
• Everolimus
• Exemestane
• 5-FU (Fluorouracil Injection)
• Fam-Trastuzumab Deruxtecan-nxki
• Fareston (Toremifene)
• Faslodex (Fulvestrant)
• Femara (Letrozole)
• Fluorouracil Injection
• Fulvestrant
• Gemcitabine Hydrochloride
• Gemzar (Gemcitabine Hydrochloride)
• Goserelin Acetate
• Halaven (Eribulin Mesylate)
• Herceptin Hylecta (Trastuzumab and Hyaluronidase-oysk)
• Herceptin (Trastuzumab)
• Ibrance (Palbociclib)
• Infugem (Gemcitabine Hydrochloride)
• Ixabepilone
• Ixempra (Ixabepilone)
• Kadcyla (Ado-Trastuzumab Emtansine)
• Keytruda (Pembrolizumab)
• Kisqali (Ribociclib)
• Lapatinib Ditosylate
• Letrozole
• Lynparza (Olaparib)
• Margenza (Margetuximab-cmkb)
• Margetuximab-cmkb
• Megestrol Acetate
• Methotrexate Sodium
• Neratinib Maleate
• Nerlynx (Neratinib Maleate)
• Olaparib
• Orserdu (Elacestrant Dihydrochloride)
• Paclitaxel
• Paclitaxel Albumin-stabilized Nanoparticle Formulation
• Palbociclib
• Pamidronate Disodium
• Pembrolizumab
• Perjeta (Pertuzumab)
• Pertuzumab
• Pertuzumab, Trastuzumab, and Hyaluronidase-zzxf
• Phesgo (Pertuzumab, Trastuzumab, and Hyaluronidase-zzxf)
• Piqray (Alpelisib)
• Ribociclib
• Sacituzumab Govitecan-hziy
• Soltamox (Tamoxifen Citrate)
• Talazoparib Tosylate
• Talzenna (Talazoparib Tosylate)
• Tamoxifen Citrate
• Taxotere (Docetaxel)
• Tecentriq (Atezolizumab)
• Tepadina (Thiotepa)
• Thiotepa
• Toremifene
• Trastuzumab
• Trastuzumab and Hyaluronidase-oysk
• Trexall (Methotrexate Sodium)
• Trodelvy (Sacituzumab Govitecan-hziy)
• Tucatinib
• Tukysa (Tucatinib)
• Tykerb (Lapatinib Ditosylate)
• Verzenio (Abemaciclib)
• Vinblastine Sulfate
• Xeloda (Capecitabine)
• Zoladex (Goserelin Acetate)

Drug Combinations Used in Breast Cancer

• AC
• AC-T
• CAF
• CMF
• FEC
• TAC

This chemotherapy combination contains the drugs doxorubicin hydrochloride (Adriamycin) and cyclophosphamide. Combinations usually work better than single drugs because different drugs kill cancer cells in different ways.

Drugs in the AC combination:

Each of the drugs in thiscombinationis approved by theFood and Drug Administration (FDA)to treat cancer or conditions related to cancer.

Use in Cancer

AC is used to treat:

• Breast cancer.

This combination may also be used with other drugs or treatments or to treat other types of cancer.

This chemotherapy combination contains the drugs doxorubicin hydrochloride (Adriamycin), cyclophosphamide, and paclitaxel (taxol). Combinations usually work better than single drugs because different drugs kill cancer cells in different ways.

Drugs in the AC-T combination:

Each of the drugs in this combination is approved by the Food and Drug Administration (FDA) to treat cancer or conditions related to cancer.

Use in Cancer

AC-T is used to treat:

• Breast cancer.

This combination may also be used with other drugs or treatments or to treat other types of cancer.

This chemotherapy combination contains the drugs cyclophosphamide, doxorubicin hydrochloride (Adriamycin), and fluorouracil. Combinations usually work better than single drugs because different drugs kill cancer cells in different ways.

Drugs in the CAF combination:

Each of the drugs in this combination is approved by the Food and Drug Administration (FDA) to treat cancer or conditions related to cancer.

Use in Cancer

CAF is used to treat:

• Breast cancer.

This combination may also be used with other drugs or treatments or to treat other types of cancer.

This chemotherapy combination contains the drugs cyclophosphamide, methotrexate, and fluorouracil. Combinations usually work better than single drugs because different drugs kill cancer cells in different ways.

Drugs in the CMF combination:

Each of the drugs in this combination is approved by the Food and Drug Administration (FDA) to treat cancer or conditions related to cancer.

Use in Cancer

CMF is used to treat:

• Breast cancer.

This combination may also be used with other drugs or treatments or to treat other types of cancer.

This chemotherapy combination contains the drugs fluorouracil, epirubicin hydrochloride, and cyclophosphamide. Combinations usually work better than single drugs because different drugs kill cancer cells in different ways.

Drugs in the FEC combination:

Each of the drugs in this combination is approved by the Food and Drug Administration (FDA) to treat cancer or conditions related to cancer.

Use in Cancer

FEC is used to treat:

• Breast cancer.

FEC is also known as CEF. This combination may also be used with other drugs or treatments or to treat other types of cancer.

This chemotherapy combination contains the drugs docetaxel (Taxotere), doxorubicin hydrochloride (Adriamycin), and cyclophosphamide. Combinations usually work better than single drugs because different drugs kill cancer cells in different ways.

Drugs in the TAC combination:

Each of the drugs in this combination is approved by the Food and Drug Administration (FDA) to treat cancer or conditions related to cancer.

Use in Cancer

TAC is used to treat:

• Breast cancer. It is often used as adjuvant therapy.

This combination may also be used with other drugs or treatments or to treat other types of cancer.