• What is the most important information I should know about Docetaxel Injection?

  Docetaxel Injection can cause serious side effects, including death.

  • The chance of death in people who receive Docetaxel Injection is higher if you:
    • have liver problems
    • receive high doses of Docetaxel Injection
    • have non-small cell lung cancer and have been treated with chemotherapy medicines that contain platinum
  • Docetaxel Injection can affect your blood cells.
    Your doctor should do routine blood tests during treatment with Docetaxel Injection. This will include regular checks of your white blood cell counts. If your white blood cells are too low, your doctor may not treat you with Docetaxel Injection until you have enough white blood cells. People with low white blood counts can develop life-threatening infections. The earliest sign of infection may be fever. Follow your doctor's instructions for how often to take your temperature during treatment with Docetaxel Injection. Call your doctor right away if you have a fever.
  • Severe allergic reactions can happen in people who receive Docetaxel Injection. If you have had an allergic reaction to the medicine paclitaxel in the past, these reactions may be more severe. Severe allergic reactions are medical emergencies that can lead to death and must be treated right away. Your doctor will monitor you closely for allergic reactions during your infusion of Docetaxel Injection.
    Tell your doctor right away if you have any of these signs of a serious allergic reaction:
    • trouble breathing
    • sudden swelling of your face, lips, tongue, throat, or trouble swallowing
    • hives (raised bumps), rash, or redness all over your body
  • Your body may hold too much fluid (severe fluid retention) during treatment with Docetaxel Injection. This can be life threatening. To decrease the chance of this happening, you must take another medicine, a corticosteroid, before each Docetaxel Injection treatment. You must take the corticosteroid exactly as your doctor tells you. Tell your doctor or nurse before your Docetaxel Injection treatment if you forget to take the corticosteroid dose or do not take it as your doctor tells you.
• What is Docetaxel Injection?
• Who should not receive Docetaxel Injection?
• What should I tell my healthcare provider before receiving Docetaxel Injection?
• How will I receive Docetaxel Injection?
• What are the possible side effects of Docetaxel Injection?
• References

These FAQs provide a summary of the most important information about Docetaxel Injection. If you would like more information or have any questions, talk to your healthcare provider.

• What is the most important information I should know about doxorubicin?

  Doxorubicin hydrochloride may cause serious side effects including:

  • Heart failure. Doxorubicin hydrochloride may cause heart muscle damage that may lead to heart failure, which is a condition in which the heart does not pump well. Heart failure is irreversible in some cases and can lead to death. Heart failure can happen during your treatment with doxorubicin hydrochloride or months to years after stopping treatment. Your risk of heart muscle damage increases with higher total amounts of doxorubicin hydrochloride that you receive in your lifetime. Your risk of heart failure is higher if you:
    • already have other heart problems
    • have had or are currently receiving radiation therapy to your chest
    • have had treatment with certain other anti-cancer medicines
    • take other medicines that can have severe side effects on your heart

  Tell your doctor if you get any of these symptoms of heart failure during or after treatment with doxorubicin hydrochloride:

  • extreme tiredness or weakness
  • fast heartbeat
  • shortness of breath
  • swelling of your feet and ankles

  Your doctor will do tests to check the strength of your heart muscle before, during, and after your treatment with doxorubicin hydrochloride.

  • Risk of new cancers. You may have an increased risk of developing certain blood cancers called acute myelogenous leukemia (AML) or myelodysplastic syndrome (MDS) after treatment with doxorubicin hydrochloride. Talk with your doctor about your risk of developing new cancers if you take doxorubicin hydrochloride.
  • Skin damage near the vein where doxorubicin hydrochlorideis given (Injection site reaction).Doxorubicin hydrochloride can damage the skin if it leaks out of the vein. Symptoms of infusion reaction include blisters and skin sores at injection site which may require skin grafts.
  • Decreased blood cell counts. Doxorubicin hydrochloride can cause a decrease in neutrophils (a type of white blood cells important in fighting bacterial infections) and platelets (important for clotting and to control bleeding). This may lead to a serious infection, the need for blood transfusions, treatment in a hospital and death. Your doctor will check your blood cell count during your treatment with doxorubicin hydrochloride and after you have stopped your treatment. Call your doctor right away if you get a fever (temperature of 100.4ºF or greater) or chills with shivering.
• What is doxorubicin?
• Who should not receive doxorubicin?
• What should I tell my doctor before receiving doxorubicin?
• How will I receive doxorubicin?
• What are the possible side effects of doxorubicin?
• References

These FAQs provide a summary of the most important information about Doxorubicin Injection. If you would like more information or have any questions, talk to your healthcare provider.

• What is cyclophosphamide?

  Cyclophosphamide is a prescription medicine used to treat many types of cancer and a certain type of kidney disease in children. Cyclophosphamide damages the cell’s DNA and may kill cancer cells. It may also lower the body’s immune response. Cyclophosphamide is a type of alkylating agent.

  Cyclophosphamide is approved to be used alone or with other drugs to treat:

  • Acute lymphoblastic leukemia (ALL) in children.
  • Acute monocytic leukemia.
  • Acute myeloid leukemia (AML).
  • Breast cancer.
  • Chronic granulocytic leukemia.
  • Chronic lymphocytic leukemia (CLL).
  • Chronic myelogenous leukemia (CML).
  • Hodgkin lymphoma. It is used in patients with stage III or stage IV disease.
  • Multiple myeloma.
  • Mycosis fungoides (a type of cutaneous T-cell lymphoma) that is advanced.
  • Neuroblastoma that is disseminated.
  • Non-Hodgkin lymphoma (NHL). It is used in patients with stage III or stage IV NHL, including the following types:
    • Lymphocytic lymphoma (nodular or diffuse).
    • Mixed-cell type lymphoma.
    • Histiocytic lymphoma.
    • Burkitt lymphoma.
  • Ovarian cancer.
  • Retinoblastoma.

  Cyclophosphamide is also being studied in the treatment of other types of cancer.

• References

These FAQs provide a summary of the most important information about Cyclophosphamide. If you would like more information or have any questions, talk to your healthcare provider.