What Is Sclerosing Epithelioid Fibrosarcoma?
Sclerosing epithelioid fibrosarcoma, or SEF, is a type of rare cancer that grows in the soft tissues and bones throughout the body. It usually grows in the arms, legs, head and neck, but can be found anywhere in the body. Soft tissues include the muscle, fat, tendons, ligaments, lymph and blood vessels, nerves, or other tissue that connects and supports the body.
SEF is a type of cancer called soft tissue sarcoma. SEF gets its name from how the cells that make up this tumor look under the microscope. The cells look like they are arranged in strands and sheets. Sometimes this tumor is confused for a different kind of rare sarcoma called fibromyxoid sarcoma, because these tumors look alike under the microscope. SEF was first described as a unique tumor in 1995.
Source: National Cancer Institute (NCI)