An injury is damage to your body. It refers to harm caused by accidents, falls, hits, weapons, and more. In the U.S., millions of people injure themselves every year. Wounds are injuries that break the skin or other body tissues. They include cuts, bites, scrapes, scratches, and punctured skin. Get first aid tips and how to deal with different injuries.
Lateral X-ray of the neck with cervical collar in a patient with Cervical Spine Trauma.
Hyperextension and hyperflexion in whiplash injury
Image by BruceBlaus
Hyperextension and hyperflexion in whiplash injury
Hyperextension and hyperflexion in whiplash injury.
Image by BruceBlaus
Wounds and Injuries
An injury is damage to your body. It is a general term that refers to harm caused by accidents, falls, hits, weapons, and more. In the U.S., millions of people injure themselves every year. These injuries range from minor to life-threatening. Injuries can happen at work or play, indoors or outdoors, driving a car, or walking across the street.
Wounds are injuries that break the skin or other body tissues. They include cuts, scrapes, scratches, and punctured skin. They often happen because of an accident, but surgery, sutures, and stitches also cause wounds. Minor wounds usually aren't serious, but it is important to clean them. Serious and infected wounds may require first aid followed by a visit to your doctor. You should also seek attention if the wound is deep, you cannot close it yourself, you cannot stop the bleeding or get the dirt out, or it does not heal.
Other common types of injuries include
Animal bites
Bruises
Burns
Dislocations
Electrical injuries
Fractures
Sprains and strains
Source: National Library of Medicine (NLM)
Additional Materials (1)
Lateral X-ray of the neck with cervical collar in a patient with Cervical Spine Trauma.
Lateral X-ray of the neck with cervical collar in a patient with Cervical Spine Trauma.
A bruise is a mark on your skin caused by blood trapped under the surface. It happens when an injury crushes small blood vessels but does not break the skin. Those vessels break open and leak blood under the skin.
Bruises are often painful and swollen. You can get skin, muscle and bone bruises. Bone bruises are the most serious.
It can take months for a bruise to fade, but most last about two weeks. They start off a reddish color, and then turn bluish-purple and greenish-yellow before returning to normal. To reduce bruising, ice the injured area and elevate it above your heart. See your health care provider if you seem to bruise for no reason, or if the bruise appears to be infected.
Source: MedlinePlus
Child Safety
Fathers
Image by CDC/ Amanda Mills
Fathers
This father was shown walking on a Georgian city street, while to his right, he was holding hands with his young daughter. They had paused at an intersection, while waiting for the crosswalk signal to indicate permission to cross the street. Adherence to the rules and regulations governing our roadways, as well as staying alert and focused on the activities taking place all around you, will make for a much safer walking experience, especially on a city street.
Image by CDC/ Amanda Mills
Child Safety
As parents, we want to keep our children safe from harm. Take steps to keep your children safe:
Install the right child safety seat in your car
Teach children how to cross the street safely
Make sure they wear the right gear and equipment for sports
Install and test smoke alarms
Store medicines, cleaners and other dangerous substances in locked cabinets
Babyproof your home
Don't leave small children unattended
Source: MedlinePlus
Additional Materials (1)
Seat Belts
This image depicts a mother in the process of securing her young daughter into her child safety seat, which was located in the vehicle’s rear seat. At this point in the process, she was adjusting her daughter’s harness, ensuring both her safety and comfort.
Image by CDC/ Amanda Mills
Seat Belts
CDC/ Amanda Mills
Electrical Injuries
Safety sign / warning sign for hazards by arc-fault effects due to electrical systems
Image by M1k3 Mark3r 911/Wikimedia
Safety sign / warning sign for hazards by arc-fault effects due to electrical systems
Safety sign / warning sign for hazards by arc-fault effects due to electrical systems in workplaces (thermal energy, pressure wave and entrained fragments, high intensity electromagnetic radiation, high acoustic loading, toxic gases and particles). The warning sign was created in orientation to ISO 7010 However, it is not a registered sign.
Image by M1k3 Mark3r 911/Wikimedia
Electrical Injuries
When you come in direct contact with electricity, it can pass through your body and cause injuries. These electrical injuries can be external or internal. You may have one or both types. External injuries are skin burns. Internal injuries include damage to your organs, bones, muscles, and nerves. You could also have abnormal heart rhythms and sudden cardiac arrest (SCA).
How bad your injuries are depends on how strong the electric current was, what type of current it was, how it moved through your body, and how long you were exposed. Other factors include how healthy you are, and how quickly you get treatment.
Causes of electrical injuries include:
Lightning strikes
Faulty electrical appliances
Work-related exposures
Contact with household wiring or power lines
Accidents in small children, when they bite or suck on electrical cords, or stick objects in outlets
If you get an electrical injury, you should see a doctor. You may have internal damage and not realize it.
Source: National Library of Medicine (NLM)
Additional Materials (14)
HOME ELECTRICAL Safety Checklist Keeping You and Your Family Safe, Room-by-Room
Document by Consumer Product Safety Commission
Injury from touching a hot electrical outlet
From accidentally touching an extremely hot electrical outlet
Image by Doggo19292/Wikimedia
Electrical cardioversion
The 'burn' mark left after a electrical cardioversion at harefield hospital august 20th 2018. dc cardioversion aftermath after one day. also one on the back.
Image by Ryaninuk at harefield hospital/Wikimedia
Electrical burn on hand
Electrical burns may show erythema and bullae from the heat of arcing current or may be non-descript with severe internal damage between the points of contact and exit of the current.
Image by National Institute for Occupational Safety and Health (NIOSH) from USA/Wikimedia
LACC | Burn | Electrical Injury | American Heart Association
Los Angeles Career College/YouTube
2:30
Electrical injury | Malar - First Aid Online Course
Malar - First Aid Online Course/YouTube
2:42
Electrical Injury
DrER.tv/YouTube
2:47
Electrical hazards
IMCA/YouTube
2:08
Electrical Safety: Crane Truck Contact
WorkSafeBC/YouTube
1:24
Dr. Marc Jeschke interview on electrical injuries - Part 1
Electrical Contractors Association of Alberta/YouTube
3:53
What Happens When You Get Electrocuted?
SciShow/YouTube
3:33
Electrical injuries on The First Aid Show
The First Aid Show/YouTube
Falls
Falling (accident)
Image by Strongarm Inc
Falling (accident)
Fall prevention / Engineering drawing of the Strongarm Forearm Crutch
Image by Strongarm Inc
Falls
Falls can be dangerous at any age. Babies and young children can get hurt falling off furniture or down the stairs. Older children may fall off playground equipment. For elderly people, falls can be especially serious. They are at higher risk of falling. They are also more likely to break a bone when they fall, especially if they have osteoporosis. A broken bone, especially when it is a hip, may even lead to disability and a loss of independence for the elderly.
Some common causes of falls include
Balance problems
Some medicines, which can make you feel dizzy, confused, or slow
Vision problems
Alcohol, which can affect your balance and reflexes
Muscle weakness, especially in your legs, which can make it harder for you to get up from a chair or keep your balance when walking on an uneven surface.
Certain illnesses, such as low blood pressure, diabetes, and neuropathy
Slow reflexes, which make it hard to keep your balance or move out of the way of a hazard
Tripping or slipping due to loss of footing or traction
At any age, people can make changes to lower their risk of falling. It important to take care of your health, including getting regular eye exams. Regular exercise may lower your risk of falls by strengthening your muscles, improving your balance, and keeping your bones strong. And you can look for ways to make your house safer. For example, you can get rid of tripping hazards and make sure that you have rails on the stairs and in the bath. To reduce the chances of breaking a bone if you do fall, make sure that you get enough calcium and vitamin D.
Source: National Institute on Aging (NIA)
Additional Materials (12)
Falling (accident)
Tripping and falling on a step
Image by KlausHausmann
Impact of Falls and Parkinson's Disease
Video by Veterans Health Administration/YouTube
How Tai Chi and Qigong exercises can help prevent falls in older adults
Video by Kaiser Permanente Thrive/YouTube
This browser does not support the video element.
Exercise & Seniors
Exercise has important benefits for seniors, including improved balance, strength and muscle mass. Balance is important in preventing falls, and overall conditioning helps seniors avoid weight gain, diabetes, and other related ailments. Seniors do not have to run marathons to achieve these results. Thirty minutes of activity a day, which can be divided up into multiple 10 or 15 minute sessions, will help most seniors maintain or improve their health.
Video by TheVisualMD
Fall Prevention Awareness: Tips for preventing falls
Video by Loyola Medicine/YouTube
Winter's Hidden Hazard - Cold Weather Health & Safety - Safety Training Video
Video by Safety Memos/YouTube
The Timed Up and Go (TUG) Test
Video by Centers for Disease Control and Prevention (CDC)/YouTube
4-Stage Balance Test
Video by Centers for Disease Control and Prevention (CDC)/YouTube
Preventing Falls, Patient Safety
Video by Hopitaux Universitaires de Genève/YouTube
Preventing Falls - Adults
Video by Singapore General Hospital/YouTube
6 Steps to Prevent a Fall
Video by National Council on Aging/YouTube
Tips for preventing falls in the hospital
Video by Michigan Medicine/YouTube
Falling (accident)
KlausHausmann
7:30
Impact of Falls and Parkinson's Disease
Veterans Health Administration/YouTube
3:20
How Tai Chi and Qigong exercises can help prevent falls in older adults
Kaiser Permanente Thrive/YouTube
2:34
Exercise & Seniors
TheVisualMD
1:30
Fall Prevention Awareness: Tips for preventing falls
Loyola Medicine/YouTube
3:00
Winter's Hidden Hazard - Cold Weather Health & Safety - Safety Training Video
Safety Memos/YouTube
1:29
The Timed Up and Go (TUG) Test
Centers for Disease Control and Prevention (CDC)/YouTube
2:07
4-Stage Balance Test
Centers for Disease Control and Prevention (CDC)/YouTube
10:12
Preventing Falls, Patient Safety
Hopitaux Universitaires de Genève/YouTube
3:03
Preventing Falls - Adults
Singapore General Hospital/YouTube
1:40
6 Steps to Prevent a Fall
National Council on Aging/YouTube
3:19
Tips for preventing falls in the hospital
Michigan Medicine/YouTube
First Aid
Cross, First Aid, Medical, Medicine
Image by GDJ/Pixabay
Cross, First Aid, Medical, Medicine
Image by GDJ/Pixabay
First Aid
Accidents happen. Someone chokes on an ice cube or gets stung by a bee. It is important to know when to call 9-1-1 -- it is for life-threatening emergencies. While waiting for help to arrive, you may be able to save someone's life. Cardiopulmonary resuscitation (CPR) is for people whose hearts or breathing has stopped and the Heimlich maneuver is for people who are choking.
You can also learn to handle common injuries and wounds. Cuts and scrapes, for example, should be rinsed with cool water. To stop bleeding, apply firm but gentle pressure, using gauze. If blood soaks through, add more gauze, keeping the first layer in place. Continue to apply pressure.
It is important to have a first aid kit available. Keep one at home and one in your car. It should include a first-aid guide. Read the guide to learn how to use the items, so you are ready in case an emergency happens.
Source: National Library of Medicine (NLM)
Additional Materials (49)
First Aid Kit
Image by stevepb/Pixabay
Child First Aid: Try first aid first for a fever
Video by British Red Cross/YouTube
Child First Aid: Try first aid first for a sprain or strain
Video by British Red Cross/YouTube
How To Use A First Aid Kit... What Your First Aid Course Didn't Teach You: Free Safety Video
Video by AMERICANCPRTRAINING/YouTube
When Seconds Count - Emergency First Aid Training
Video by AmericanSafetyEMT/YouTube
How to help someone with a burn | British Red Cross | First Aid
Video by British Red Cross/YouTube
What to do if you fall, first aid and how to get up
Video by First Aid for Life/YouTube
How to Treat Someone for Food Poisoning | First Aid Training
Video by Howcast/YouTube
How to Recognize & Treat Frostbite | First Aid Training
Video by Howcast/YouTube
How to Treat an Insect Bite or Sting | First Aid Training
Video by Howcast/YouTube
How to Treat a Nosebleed | First Aid Training
Video by Howcast/YouTube
How to Stop Bleeding | First Aid Training
Video by Howcast/YouTube
How to Treat an Animal Bite | First Aid Training
Video by Howcast/YouTube
How to Recognize & Treat Hypothermia | First Aid Training
Video by Howcast/YouTube
How to Treat a Black Eye | First Aid Training
Video by Howcast/YouTube
How to Treat a Blister | First Aid Training
Video by Howcast/YouTube
How to Give the Heimlich Maneuver | First Aid Training
Video by Howcast/YouTube
How to Treat Poisoning | First Aid Training
Video by Howcast/YouTube
Burn First Aid / Premiers soins pour les brûlures
Video by AboutKidsHealth/YouTube
Gunshot Wound First Aid
Video by AmericanSafetyEMT/YouTube
Children First Aid: Head Injury
Video by British Red Cross/YouTube
Children First Aid: Vomiting and Diarrhoea
Video by British Red Cross/YouTube
Children First Aid: Poisoning and harmful substances
Video by British Red Cross/YouTube
Children First Aid: Meningitis
Video by British Red Cross/YouTube
First Aid Tips : How to Treat Food Poisoning
Video by eHow/YouTube
First Aid Tips : How to Relieve a Bee Sting
Video by eHow/YouTube
First Aid Tips : How to Treat a Punctured Lung
Video by eHow/YouTube
First Aid Tips : Treating Cat Bites
Video by eHow/YouTube
First Aid Tips : How to Treat a Jammed Finger or Toe
Video by eHow/YouTube
Basic First Aid : How to Treat a Rib Fracture
Video by eHow/YouTube
Basic First Aid : How to Treat a Knee Sprain
Video by eHow/YouTube
First Aid Tips : How to Treat Blisters
Video by eHow/YouTube
An Overview of Epilepsy and Seizure First Aid
Video by Epilepsy Foundation/YouTube
Seizure First Aid Animation
Video by EPILEPSYTV/YouTube
First Aid for Insect Bites : How to Treat a Hornet Sting
Video by ExpertVillage Leaf Group/YouTube
First Aid & Safety Procedures : How to Identify & Treat Black Widow Spider Bites
Video by ExpertVillage Leaf Group/YouTube
Fainting First Aid - Learn what to do when somebody's fainting in 1 minute
Video by Healthchanneltv / cherishyourhealthtv/YouTube
Nose Bleed First Aid - Learn how you stop a bleeding nose in 1 minute
Video by Healthchanneltv / cherishyourhealthtv/YouTube
Choking First Aid: Learn how to save someone who is choking
Video by Healthchanneltv / cherishyourhealthtv/YouTube
Minor Burn First Aid - Learn how to treat minor burns in less than 1 minute
Video by Healthchanneltv / cherishyourhealthtv/YouTube
First Aid for a Child Choking
Video by Nicklaus Children's Hospital/YouTube
First Aid For Burns Cool, Call, Cover
Video by Queen Victoria Hospital/YouTube
Unconscious but breathing First Aid: Learn how to put someone in the recovery position
Video by Healthchanneltv / cherishyourhealthtv/YouTube
First Aid - Animation
Video by Saad Zuki/YouTube
What to do if your Baby is Drowning - First Aid Training - St John Ambulance
Video by St John Ambulance/YouTube
What To Do When Someone Is Choking - First Aid Training - St John Ambulance
Video by St John Ambulance/YouTube
How to Survive a Heart Attack: Symptoms and First Aid for Heart Attack
Video by Tiny Medicine/YouTube
First Aid in Seizures
Video by Apollo Hospitals/YouTube
How to help someone with a nosebleed | British Red Cross | First Aid
Video by British Red Cross/YouTube
First Aid Kit
stevepb/Pixabay
1:13
Child First Aid: Try first aid first for a fever
British Red Cross/YouTube
1:10
Child First Aid: Try first aid first for a sprain or strain
British Red Cross/YouTube
21:03
How To Use A First Aid Kit... What Your First Aid Course Didn't Teach You: Free Safety Video
AMERICANCPRTRAINING/YouTube
12:40
When Seconds Count - Emergency First Aid Training
AmericanSafetyEMT/YouTube
0:32
How to help someone with a burn | British Red Cross | First Aid
British Red Cross/YouTube
5:00
What to do if you fall, first aid and how to get up
First Aid for Life/YouTube
1:18
How to Treat Someone for Food Poisoning | First Aid Training
Howcast/YouTube
1:43
How to Recognize & Treat Frostbite | First Aid Training
Howcast/YouTube
2:10
How to Treat an Insect Bite or Sting | First Aid Training
Howcast/YouTube
2:03
How to Treat a Nosebleed | First Aid Training
Howcast/YouTube
2:04
How to Stop Bleeding | First Aid Training
Howcast/YouTube
1:28
How to Treat an Animal Bite | First Aid Training
Howcast/YouTube
1:29
How to Recognize & Treat Hypothermia | First Aid Training
Howcast/YouTube
1:47
How to Treat a Black Eye | First Aid Training
Howcast/YouTube
0:50
How to Treat a Blister | First Aid Training
Howcast/YouTube
2:20
How to Give the Heimlich Maneuver | First Aid Training
Howcast/YouTube
1:32
How to Treat Poisoning | First Aid Training
Howcast/YouTube
3:43
Burn First Aid / Premiers soins pour les brûlures
AboutKidsHealth/YouTube
5:58
Gunshot Wound First Aid
AmericanSafetyEMT/YouTube
1:14
Children First Aid: Head Injury
British Red Cross/YouTube
1:14
Children First Aid: Vomiting and Diarrhoea
British Red Cross/YouTube
1:04
Children First Aid: Poisoning and harmful substances
British Red Cross/YouTube
1:06
Children First Aid: Meningitis
British Red Cross/YouTube
1:44
First Aid Tips : How to Treat Food Poisoning
eHow/YouTube
1:47
First Aid Tips : How to Relieve a Bee Sting
eHow/YouTube
2:28
First Aid Tips : How to Treat a Punctured Lung
eHow/YouTube
1:35
First Aid Tips : Treating Cat Bites
eHow/YouTube
2:24
First Aid Tips : How to Treat a Jammed Finger or Toe
eHow/YouTube
2:14
Basic First Aid : How to Treat a Rib Fracture
eHow/YouTube
2:03
Basic First Aid : How to Treat a Knee Sprain
eHow/YouTube
1:49
First Aid Tips : How to Treat Blisters
eHow/YouTube
11:38
An Overview of Epilepsy and Seizure First Aid
Epilepsy Foundation/YouTube
4:01
Seizure First Aid Animation
EPILEPSYTV/YouTube
1:26
First Aid for Insect Bites : How to Treat a Hornet Sting
ExpertVillage Leaf Group/YouTube
1:58
First Aid & Safety Procedures : How to Identify & Treat Black Widow Spider Bites
ExpertVillage Leaf Group/YouTube
1:20
Fainting First Aid - Learn what to do when somebody's fainting in 1 minute
Healthchanneltv / cherishyourhealthtv/YouTube
1:23
Nose Bleed First Aid - Learn how you stop a bleeding nose in 1 minute
Healthchanneltv / cherishyourhealthtv/YouTube
1:31
Choking First Aid: Learn how to save someone who is choking
Healthchanneltv / cherishyourhealthtv/YouTube
1:12
Minor Burn First Aid - Learn how to treat minor burns in less than 1 minute
Healthchanneltv / cherishyourhealthtv/YouTube
6:12
First Aid for a Child Choking
Nicklaus Children's Hospital/YouTube
2:51
First Aid For Burns Cool, Call, Cover
Queen Victoria Hospital/YouTube
1:29
Unconscious but breathing First Aid: Learn how to put someone in the recovery position
Healthchanneltv / cherishyourhealthtv/YouTube
5:05
First Aid - Animation
Saad Zuki/YouTube
3:48
What to do if your Baby is Drowning - First Aid Training - St John Ambulance
St John Ambulance/YouTube
2:25
What To Do When Someone Is Choking - First Aid Training - St John Ambulance
St John Ambulance/YouTube
3:33
How to Survive a Heart Attack: Symptoms and First Aid for Heart Attack
Tiny Medicine/YouTube
3:12
First Aid in Seizures
Apollo Hospitals/YouTube
0:22
How to help someone with a nosebleed | British Red Cross | First Aid
If you've ever gotten a splinter or had sand in your eye, you've had experience with a foreign body. A foreign body is something that is stuck inside you but isn't supposed to be there. You may inhale or swallow a foreign body, or you may get one from an injury to almost any part of your body. Foreign bodies are more common in small children, who sometimes stick things in their mouths, ears, and noses.
Some foreign bodies, like a small splinter, do not cause serious harm. Inhaled or swallowed foreign bodies may cause choking or bowel obstruction and may require medical care.
Source: MedlinePlus
Safety
Motor Vehicle Safety
Image by Maksim
Motor Vehicle Safety
Visualisation of how a car deforms in an asymmetrical crash using finite element analysis.
Image by Maksim
Safety
You can't remove all the safety hazards from your life, but you can reduce them. To avoid many major hazards and prepare for emergencies
Keep emergency phone numbers by your telephones
Make a first aid kit for your home
Make a family emergency plan
Install and maintain smoke alarms and carbon monoxide detectors
Keep guns unloaded and locked up. Lock up the ammunition separately.
Follow the directions carefully when using tools or equipment
Young children are especially at risk. Supervision is the best way to keep them safe. Childproofing the house can also help.
Source: NIH
Additional Materials (16)
Food Safety Moms-to-Be -- 4 Steps to Food Safety
Video by U.S. Food and Drug Administration/YouTube
Colonel Jeff Cooper's Rules of Firearm Safety | Gunsite Academy Firearms Training
Video by National Shooting Sports Foundation | NSSF/YouTube
Leading safety into the future: Teen driving
Video by NatlSafetyCouncil/YouTube
Types of Child Proofing. Advice from Child Safety expert.
Video by Baby Care 101/YouTube
Pain Medication Safety - Mayo Clinic
Video by Mayo Clinic/YouTube
Firearm Safety First, Last, Always | NSSF
Video by National Shooting Sports Foundation | NSSF/YouTube
Ladders & Falls - Safety Training Video - Prevent Fatal Accidents on Ladders
Video by Safety Memos/YouTube
Bloodborne Pathogens - Workplace Dangers and Disease Prevention - Health & Safety Training Video
Video by Safety Memos/YouTube
Strains and Sprains OUCH! - Avoid Painful Muscle, Tendon or Ligament Injury - Safety Training Video
Video by Safety Memos/YouTube
Hot Enough For You? - Avoid Heat Illness and Injury - Safety Training Video
Video by Safety Memos/YouTube
Park Safety Tips: Wildlife Safety
Video by sccparks/YouTube
Air Force Explore
WRIGHT-PATTERSON AIR FORCE BASE, Ohio - The Air Force unveiled Air Force Explore, a new opportunity call for capability ideas that advance the transformational component of the Air Force Science and Technology 2030 strategy, Sept. 26. With this nationwide call, the Air Force is seeking disruptive ideas that can create remarkable new capabilities for the future force.
Image by Courtesy graphic; www.jbsa.mil
Basic Food Safety: Chapter 1 "The Importance of Food Safety" (English)
Winter's Hidden Hazard - Cold Weather Health & Safety - Safety Training Video
Safety Memos/YouTube
6:38
Deadly Cold Exposure - Cold Weather Safety Tips - Safety Training Video
Safety Memos/YouTube
Scars
Scars
Image by Cory Doctorow from London, UK
Scars
Euler's identity scarification, 3PiCon, Springfield, MA
Image by Cory Doctorow from London, UK
Scars
A scar is a permanent patch of skin that grows over a wound. It forms when your body heals itself after a cut, scrape, burn, or sore. You can also get scars from surgery that cuts through the skin, infections like chickenpox, or skin conditions like acne. Scars are often thicker, as well as pinker, redder, or shinier, than the rest of your skin.
How your scar looks depends on
How big and deep your wound is
Where it is
How long it takes to heal
Your age
Your inherited tendency to scar
Scars usually fade over time but never go away completely. If the way a scar looks bothers you, various treatments might minimize it. These include surgical revision, dermabrasion, laser treatments, injections, chemical peels, and creams.
Source: National Institute of Arthritis and Musculoskeletal and Skin Diseases
Additional Materials (17)
Keloid Scarring and how it occurs
Video by Nathan Devery/YouTube
Being Confident With Facial Scarring | Phyllida | Skin Deep
Video by BBC Three/YouTube
The Best Acne Scar Treatments: Explained | Dr Davin Lim
Video by Dr Davin Lim/YouTube
How to Keep a Cut From Scarring
Video by Howcast/YouTube
Acne
Video by Focus Medica/YouTube
Acne Pathophsyiology
Video by Armando Hasudungan/YouTube
Acne When You're Older (College Health Guru)
Video by Healthguru/YouTube
Does stress cause pimples? - Claudia Aguirre
Video by TED-Ed/YouTube
How do scars form? - Sarthak Sinha
Video by TED-Ed/YouTube
Acne - Oral Antibiotics in Acne Treatment
Video by skinexpertstalk/YouTube
The Science of Pimples, Wrinkles and Moles!
Video by Life Noggin/YouTube
Is There A Pimple Cure?
Video by AsapSCIENCE/YouTube
Acne Animation
Video by Blausen Medical Corporate/YouTube
Understanding Acne (Acne #1)
Video by Healthguru/YouTube
What's That Zit (Types of Acne)? (Acne #2)
Video by Healthguru/YouTube
Acne Scars (Acne #6)
Video by Healthguru/YouTube
I Got Rid Of My Acne Scars With Laser Treatment
Video by As/Is/YouTube
1:07
Keloid Scarring and how it occurs
Nathan Devery/YouTube
2:14
Being Confident With Facial Scarring | Phyllida | Skin Deep
BBC Three/YouTube
12:02
The Best Acne Scar Treatments: Explained | Dr Davin Lim
Dr Davin Lim/YouTube
1:59
How to Keep a Cut From Scarring
Howcast/YouTube
1:15
Acne
Focus Medica/YouTube
6:58
Acne Pathophsyiology
Armando Hasudungan/YouTube
2:32
Acne When You're Older (College Health Guru)
Healthguru/YouTube
3:55
Does stress cause pimples? - Claudia Aguirre
TED-Ed/YouTube
3:42
How do scars form? - Sarthak Sinha
TED-Ed/YouTube
3:47
Acne - Oral Antibiotics in Acne Treatment
skinexpertstalk/YouTube
2:46
The Science of Pimples, Wrinkles and Moles!
Life Noggin/YouTube
3:39
Is There A Pimple Cure?
AsapSCIENCE/YouTube
0:29
Acne Animation
Blausen Medical Corporate/YouTube
3:10
Understanding Acne (Acne #1)
Healthguru/YouTube
2:23
What's That Zit (Types of Acne)? (Acne #2)
Healthguru/YouTube
3:03
Acne Scars (Acne #6)
Healthguru/YouTube
5:37
I Got Rid Of My Acne Scars With Laser Treatment
As/Is/YouTube
Surgery
A medical illustration depicting open heart surgery.
Image by BruceBlaus
A medical illustration depicting open heart surgery.
A medical illustration depicting open heart surgery.
Image by BruceBlaus
Surgery
There are many reasons to have surgery. Some operations can relieve or prevent pain. Others can reduce a symptom of a problem or improve some body function. Some surgeries are done to find a problem. For example, a surgeon may do a biopsy, which involves removing a piece of tissue to examine under a microscope. Some surgeries, like heart surgery, can save your life.
Some operations that once needed large incisions (cuts in the body) can now be done using much smaller cuts. This is called laparoscopic surgery. Surgeons insert a thin tube with a camera to see, and use small tools to do the surgery.
After surgery there can be a risk of complications, including infection, too much bleeding, reaction to anesthesia, or accidental injury. There is almost always some pain with surgery.
Source: Agency for Healthcare Research and Quality
Additional Materials (4)
Sensitive content
This media may include sensitive content
Gallbladder surgery - umbilicus
Post gallbladder surgery - umbilical area
Image by Rosetheboston/Wikimedia
Surgery Room of the Future
Surgery Room of the Future
Image by alan9187
Surgeon after completing surgery
Surgeon after completing surgery
Image by Surgilicious/Wikimedia
CIGMIT Operation Theatre - The connecting operating theatre with scanning room
The connecting operating theatre with scanning room
Image by Hidayat.ismail/Wikimedia
Sensitive content
This media may include sensitive content
Gallbladder surgery - umbilicus
Rosetheboston/Wikimedia
Surgery Room of the Future
alan9187
Surgeon after completing surgery
Surgilicious/Wikimedia
CIGMIT Operation Theatre - The connecting operating theatre with scanning room
Hidayat.ismail/Wikimedia
Laceration
Sensitive content
This media may include sensitive content
Wound Healing
Image by Raquel Baranow/Wikimedia
Sensitive content
This media may include sensitive content
Wound Healing
3 June 2017 I injured myself hiking. Not sure how it happened, all I remember was heaving a heavy rock, slipping and then falling backwards into the deep water. As I fell I could see the injury on my shin and said to myself, "you're okay Raquel". Wrist was also injured, still (four months after) there’s a hematoma on my cheekbone. Was treating the wound with Neosporin but later a wound specialist gave me medicinal honey made with special pollen from New Zealand. The same doctor who stitched me up misdiagnosed skin infection (Cellulitis, note the purple marker on my leg in one of the photos) and gave me nasty antibiotics (Clindamycin), which made me feel sick. Had to hike a mile to the car in 103-degree weather, soaked my dress in the water, got to the car, ate an Ativan and drove to the hospital. Doctor asked if anything hurt, I said "no." Endorphins are powerful painkillers, I kept telling the nurses, "I'm lucky to be alive"! Took about 5 weeks to heal. Canyon is where I heaved the rock and slipped, over on the left, slightly out of the picture. It was the last pic I took that day.
Image by Raquel Baranow/Wikimedia
Laceration
Lacerations are a pattern of injury in which skin and underlying tissues are cut or torn. Healthcare providers encounter lacerations regularly. It was reported in 2005 that nearly 12% of all ER visits, or 13.8 million visits occurred for laceration care. Lacerations can be managed in the outpatient setting as well, depending on the location and severity of the injury.
The clinical presentation of lacerations can be highly variable based on location, depth, width, and length. Due to this highly variable presentation, the healthcare team must have a strong understanding of the critical history and physical exam items each laceration requires.
Indications
To best assess the future care requirements of any laceration, the healthcare team must first review the patient's history as well as do a complete physical examination of the wound and nearby structures.
Pertinent history items include:
Time of initial injury
Location of laceration and extremity injuries have an increased risk of infection.
Measurements of laceration, including length, width, and depth. As the depth and width of injuries increase, the risk of infection increases.
Mechanisms of injury, such as crush, sharp object, and shear from fall. Crush injuries with localized tissue injury have an increased risk of infection and scarring.
Age, because at the extremes of age, there is a risk of poor healing.
Past medical history, specifically any history of diabetes mellitus, chronic renal failure, obesity, malnutrition, or any use of immunosuppression drugs such as chemotherapy medications.
Allergies, specifically to latex, anesthetics, or antibiotics.
Immunization status, note the patient's tetanus vaccine history. Current guidelines for tetanus are:
Adults with greater than or equal to three previous tetanus doses:
Clean wounds: Tdap (tetanus, reduced diphtheria, pertussis) or Td (tetanus, reduced diphtheria) only if it has been over 10 years since their last vaccination.
Dirty/complex wounds: Tdap or Td if more than 5 years since their last vaccination.
Adults with under 3 previous tetanus doses:
All wounds: Tdap or Td required; if dirty/complex, they will also require immunoglobulin treatment.
Children:
Under 7 years old: DTaP (diphtheria, tetanus, pertussis) vaccine is the recommendation; if pertussis is contraindicated, give DT (diphtheria, tetanus) vaccine.
7 to 9 years old: Td vaccine recommended.
Over 10 years old: Tdap is preferred in patients who have never received it and have no contraindications; if age or contraindications exist, use the Td vaccine.
Keys to a good physical exam of lacerations:
Ensure appropriate lighting, gauze, and rinse materials are easily accessible before beginning the exam.
Establish hemostasis: Hemostasis should be established to allow for visualization of underlying structures and foreign objects, utilizing direct pressure.
Detailed neurologic exam: The clinician should perform a complete sensation exam at and below the level of injury before the use of any anesthesia to assess for any nerve injury. A quick method to evaluate for nerve injury is two-point discrimination using a standard paper clip, always comparing to the patient's noninjured side.
Detailed musculoskeletal exam: Examine any joints involved in the laceration for injury, along with an active and passive range of motion exam above and below the joint to assess for tendon injury.
Detailed Vascular exam: Assess capillary refill in the distal to the wound if on the extremities, and compare to noninjured side always. If accessible, Doppler ultrasound can be utilized to assess underlying vascular integrity, following from above the laceration to below.
Foreign bodies, if observed, should be removed, as they can increase the patient's risk of infection or poor wound healing. If there is any concern about retained foreign bodies, imaging should be obtained.
Pediatric Abusive Head Trauma: Recommended Definitions for Public Health Surveillance and Research
Pediatric Abusive Head Trauma: Recommended Definitions for Public Health Surveillance and Research
Document by CDC
Sensitive content
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Lacerations
Megan Caberto, daughter of Col. Steven Caberto, 52nd Medical Group deputy commander, receives a facial laceration moulage during Exercise Saber Crown
Image by U.S. Air Force photo/Staff Sgt. Kristin Ruleau
Wound healing
Illustration from Anatomy & Physiology, Connexions Web site. http://cnx.org/content/col11496/1.6/, Jun 19, 2013.
Image by OpenStax College
Lacerations
sewed wound, four stitches
Image by Carsten Niehaus (Lumbar)
Properly Cleaning your wounds and lacerations
Image by Hans/Pixabay
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Facial trauma
Sutures may be used to close wounds of a superficial facial trauma.
Image by dbenzhuser
Borderline Personality Disorder
Self-inflicted lacerations on right upper arm , with a bread knife
Image by The-Speedrider
Lacerations
ClockFace
Pediatric Abusive Head Trauma: Recommended Definitions for Public Health Surveillance and Research
CDC
Sensitive content
This media may include sensitive content
Lacerations
U.S. Air Force photo/Staff Sgt. Kristin Ruleau
Wound healing
OpenStax College
Lacerations
Carsten Niehaus (Lumbar)
Properly Cleaning your wounds and lacerations
Hans/Pixabay
Sensitive content
This media may include sensitive content
Facial trauma
dbenzhuser
Borderline Personality Disorder
The-Speedrider
Animal Bites
Animal Bites Dog bite
Image by Nicor
Animal Bites Dog bite
Three days old dog bite
Image by Nicor
Animal Bites
Wild animals usually avoid people. They might attack, however, if they feel threatened, are sick, or are protecting their young or territory. Attacks by pets are more common. Animal bites rarely are life-threatening, but if they become infected, you can develop serious medical problems.
To prevent animal bites and complications from bites
Never pet, handle, or feed unknown animals
Leave snakes alone
Watch your children closely around animals
Vaccinate your cats, ferrets, and dogs against rabies
Spay or neuter your dog to make it less aggressive
Get a tetanus booster if you have not had one recently
Wear boots and long pants when you are in areas with venomous snakes
If an animal bites you, clean the wound with soap and water as soon as possible. Get medical attention if necessary.
Source: Centers for Disease Control and Prevention
Additional Materials (12)
Ellsworth dog bite
Sergeant Nelson wears a “bite suit” to protect his legs from serious injury during the training.
Image by U.S. Air Force photo/Airman 1st Class Anthony Sanchelli
Adhesive bandage on a hand following a dog bite, Singapore - 20121225
An adhesive bandage on an hand following a bite by a Shiba Inu in Singapore.
Image by Jacklee/Wikimedia
Building bonds with man's best friend
Habo, 99th Security Forces Squadron military working dog, bites on a padded sleeve August 7, 2017, at Nellis Air Force Base, Nevada. MWDs are trained to pursue and bite suspects that pose an immediate threat. (U.S. Air Force photo by Airman 1st Class Andrew D. Sarver/Released)
Image by U.S. Air Force photo by Airman 1st Class Andrew D. Sarver/Released
Animal Bites
CAMP BLUE DIAMOND, Iraq (Nov. 2, 2007) - U.S. Marine Hospital Medic Louis Kost assigned to the II Marine Expeditionary Force (II MEF), Military Iraqi Transition Team (MITT), gets attacked by Bruno, a Military Working Dog, trained by U.S. Marine Lance Cpl. Justin Granado on board Camp Blue Diamond. Granado and Bruno help MITT search for combat explosives as well as insurgents throughout Ramadi, Iraq. U.S. Marine Corps photo by Lance Cpl. Julian Billmair (RELEASED)
Image by U.S. Marine Corps photo by Lance Cpl. Julian Billmair
Animal Bites
Animal Bites
Image by Thomas / Chenoa Manor
Animal Bites - What You Need To Know
Video by Rehealthify/YouTube
Rabies Diagnosis
Video by MonkeySee/YouTube
Rabies Prevention in the United States
Video by Centers for Disease Control and Prevention (CDC)/YouTube
Cat Bites and Wound Care - Mayo Clinic
Video by Mayo Clinic/YouTube
Treatment of Pet Bites
Video by Lee Health/YouTube
Animal and Human Bites
Video by ProCPR/YouTube
Animal Bites and Scratches
Video by The First Aid Show/YouTube
Ellsworth dog bite
U.S. Air Force photo/Airman 1st Class Anthony Sanchelli
Adhesive bandage on a hand following a dog bite, Singapore - 20121225
Jacklee/Wikimedia
Building bonds with man's best friend
U.S. Air Force photo by Airman 1st Class Andrew D. Sarver/Released
Animal Bites
U.S. Marine Corps photo by Lance Cpl. Julian Billmair
Animal Bites
Thomas / Chenoa Manor
1:43
Animal Bites - What You Need To Know
Rehealthify/YouTube
3:36
Rabies Diagnosis
MonkeySee/YouTube
1:39
Rabies Prevention in the United States
Centers for Disease Control and Prevention (CDC)/YouTube
2:04
Cat Bites and Wound Care - Mayo Clinic
Mayo Clinic/YouTube
1:44
Treatment of Pet Bites
Lee Health/YouTube
4:23
Animal and Human Bites
ProCPR/YouTube
2:42
Animal Bites and Scratches
The First Aid Show/YouTube
Burns
Burns Fact Sheet
Image by BruceBlaus
Burns Fact Sheet
Image by BruceBlaus
Burns
A burn is damage to your body's tissues caused by heat, chemicals, electricity, sunlight, or radiation. Scalds from hot liquids and steam, building fires and flammable liquids and gases are the most common causes of burns. Another kind is an inhalation injury, caused by breathing smoke.
There are three types of burns:
First-degree burns damage only the outer layer of skin
Second-degree burns damage the outer layer and the layer underneath
Third-degree burns damage or destroy the deepest layer of skin and tissues underneath
Burns can cause swelling, blistering, scarring and, in serious cases, shock, and even death. They also can lead to infections because they damage your skin's protective barrier. Treatment for burns depends on the cause of the burn, how deep it is, and how much of the body it covers. Antibiotic creams can prevent or treat infections. For more serious burns, treatment may be needed to clean the wound, replace the skin, and make sure the patient has enough fluids and nutrition.
Source: NIH: National Institute of General Medical Sciences
EyeSmart — American Academy of Ophthalmology/YouTube
1:35
Detergent pods linked to eye burns
CBC News/YouTube
3:55
How to care for your child's healing skin after a burn / Soigner une brûlure en voie de guérison
AboutKidsHealth/YouTube
1:55
Crazy Creams; Facts about Burn Healing / Faits et mythes sur les soins des brûlures
AboutKidsHealth/YouTube
3:43
Burn First Aid / Premiers soins pour les brûlures
AboutKidsHealth/YouTube
1:57
Simple burn care at home / Soins des petites brûlures à la maison
AboutKidsHealth/YouTube
0:32
How to help someone with a burn | British Red Cross | First Aid
British Red Cross/YouTube
1:55
UC San Diego Health Burn Care
UC San Diego Health/YouTube
1:50
How to treat a first degree (minor) burn
American Academy of Dermatology/YouTube
4:33
What Really Causes Sunburns?
Gross Science/YouTube
What Is a Burn?
Superficial (first-degree)
Scaldburn
Major-2nd-degree-burn
8-day-old-3rd-degree-burn
2nd- to 4th-degree electrical hand burns with tissue charring
1
2
3
4
5
1) Superficial (first-degree) 2) Superficial partial thickness (2nd-degree) 3) Deep partial thick Extends in
Superficial (first-degree)
Scaldburn
Major-2nd-degree-burn
8-day-old-3rd-degree-burn
2nd- to 4th-degree electrical hand burns with tissue charring
1
2
3
4
5
1) Superficial (first-degree) 2) Superficial partial thickness (2nd-degree) 3) Deep partial thick Extends in
Burns :
1) Superficial (first-degree) Author : QuinnHK
2) Superficial partial thickness (second-degree). Local infection (cellulitis) but no scarring typically. Scalding caused by a radiator explosion. Author Snickerdo
3) Extends into deep (reticular) dermis - Major 2nd-degree burn (boiling water) Author - Westchaser
4) Full thickness (third-degree - Extends through entire dermis - 8-day-old-3rd-degree-burn Author : Craig0927
5) Fourth-degree, Extends through entire skin, and into underlying fat, muscle and bone - 2nd- to 4th-degree electrical hand burns with tissue charring - Author : goga312
What Is a Burn?
A burn is tissue damage caused by heat, chemicals, electricity, sunlight, or nuclear radiation. The most common burns are those caused by hot liquid or steam, building fires, and flammable liquids and gases.
Burns are defined by how deep they are and how large an area they cover. A large burn injury is likely to include burned areas of different depths.
Deep burns heal more slowly, are more difficult to treat, and are more prone to complications such as infections and scarring. Very deep burns are the most life-threatening of all and may require amputation. Types of burns include:
First-degree burns damage the outer layer (epidermis) of the skin. These burns usually heal on their own within a week. A common example is a sunburn.
Second-degree burns damage not only the outer layer but also the layer beneath it (dermis). These burns might need a skin graft—natural or artificial skin to cover and protect the body while it heals—and they may leave a scar.
Third-degree burns damage or completely destroy both layers of skin including hair follicles and sweat glands and damage underlying tissues. These burns always require skin grafts.
Fourth degree burns extend into fat, fifth degree burns into muscle, and sixth degree burns to bone.
Cross-section of skin anatomy shows layers and different tissue types. Credit: NIGMS.
Source: National Institute of General Medical Sciences (NIGMS)
Additional Materials (1)
How To Grade BURNS - 1st, 2nd, 3rd and 4th Degree Burns Explained
Video by RN Kid/YouTube
3:00
How To Grade BURNS - 1st, 2nd, 3rd and 4th Degree Burns Explained
RN Kid/YouTube
How Does the Body React to a Severe Burn?
Burn Degree Diagram
Image by K. Aainsqatsi at en.wikipedia
Burn Degree Diagram
Image by K. Aainsqatsi at en.wikipedia
How Does the Body React to a Severe Burn?
Severe burns cause serious, body-wide problems. At the root of most of these problems is the body’s explosive inflammatory response.
A normal inflammatory response protects the body from invaders, such as bacteria, viruses, fungi, cancerous cells, toxins, and foreign materials. It activates in response to infection, injury, or other threat. It is designed to destroy the cause of the problem, contain the damage, and clean up the mess left by dead cells and other debris. But when faced with large or deep burns, it can overreact, often making the injury more severe and harming the heart, lungs, blood vessels, kidneys, and other organ systems.
During this inflammatory response, there is fluid loss that can cause a sharp and potentially deadly drop in blood pressure known as shock. Fluid can also become trapped inside the body, leading to swelling known as edema. If tissues and organs do not receive enough oxygen because of shock, edema, or something else, they suffer damage and can fail. The lungs, heart, brain, and kidneys are particularly susceptible.
Infection is also a major concern. Burns damage the skin’s protective barrier, meaning bacteria and other foreign invaders can sneak in. Burns also weaken the immune system, so the body is less able to fight off threats. Infections can take hold not only in the injured area, but also in organs such as the lungs (pneumonia) and bloodstream (sepsis), where they are potentially lethal.
Source: National Institute of General Medical Sciences (NIGMS)
The size of a burn will guide decisions made about the need for specialized treatment. Specific parts of the body are associated with a percentage of body area.
X-ray showing a joint dislocation of the left hip.
Image by Hellerhoff
Joint Dislocations
Dislocations are joint injuries that force the ends of your bones out of position. The cause is often a fall or a blow, sometimes from playing a contact sport. You can dislocate your ankles, knees, shoulders, hips, elbows and jaw. You can also dislocate your finger and toe joints. Dislocated joints often are swollen, very painful and visibly out of place. You may not be able to move it.
A dislocated joint is an emergency. If you have one, seek medical attention. Treatment depends on which joint you dislocate and the severity of the injury. It might include manipulations to reposition your bones, medicine, a splint or sling, and rehabilitation. When properly repositioned, a joint will usually function and move normally again in a few weeks. Once you dislocate a shoulder or kneecap, you are more likely to dislocate it again. Wearing protective gear during sports may help prevent dislocations.
Source: National Institute of Arthritis and Musculoskeletal and Skin Diseases
Perilunar dislocation with dorsal dislocation of the capitate and fracture through the scaphoid with displacement of the distal end also dorsal.
Interactive by Hellerhoff
Dislocated joints on The First Aid Show
Video by The First Aid Show/YouTube
WATCH: Relocating My Patient's Finger
Video by Institute of Human Anatomy/YouTube
If Your Baby has a Dislocated Joint - First Aid Training - St John Ambulance
Video by St John Ambulance/YouTube
Barlow & Ortolani test, Congenital Hip Dislocation- Everything You Need To Know - Dr. Nabil Ebraheim
Video by nabil ebraheim/YouTube
Shoulder Dislocation
Video by ORTHOfilms/YouTube
Traumatic Knee Dislocation Reduction-Quick Version
Video by Larry Mellick/YouTube
Thumb Dislocation Reduction
Video by Larry Mellick/YouTube
Hip Dislocations - Everything You Need To Know - Dr. Nabil Ebraheim
Video by nabil ebraheim/YouTube
Elbow Dislocations - Everything You Need To Know - Dr. Nabil Ebraheim
Video by nabil ebraheim/YouTube
Dislocations Of The Finger - Everything You Need To Know - Dr. Nabil Ebraheim
Video by nabil ebraheim/YouTube
Sternoclavicular joint Dislocations - Everything You Need To Know - Dr. Nabil Ebraheim
Video by nabil ebraheim/YouTube
Joint Dislocations - Perilunar dislocation
Hellerhoff
1:36
Dislocated joints on The First Aid Show
The First Aid Show/YouTube
11:10
WATCH: Relocating My Patient's Finger
Institute of Human Anatomy/YouTube
1:31
If Your Baby has a Dislocated Joint - First Aid Training - St John Ambulance
St John Ambulance/YouTube
4:58
Barlow & Ortolani test, Congenital Hip Dislocation- Everything You Need To Know - Dr. Nabil Ebraheim
nabil ebraheim/YouTube
1:21
Shoulder Dislocation
ORTHOfilms/YouTube
5:30
Traumatic Knee Dislocation Reduction-Quick Version
Larry Mellick/YouTube
3:17
Thumb Dislocation Reduction
Larry Mellick/YouTube
4:25
Hip Dislocations - Everything You Need To Know - Dr. Nabil Ebraheim
nabil ebraheim/YouTube
3:10
Elbow Dislocations - Everything You Need To Know - Dr. Nabil Ebraheim
nabil ebraheim/YouTube
3:59
Dislocations Of The Finger - Everything You Need To Know - Dr. Nabil Ebraheim
nabil ebraheim/YouTube
3:59
Sternoclavicular joint Dislocations - Everything You Need To Know - Dr. Nabil Ebraheim
nabil ebraheim/YouTube
Joint Dislocations
X ray of a dislocated right elbow.
Image by James Heilman, MD/Wikimedia
X ray of a dislocated right elbow.
AP X ray of a dislocated right elbow.
Image by James Heilman, MD/Wikimedia
Joint Dislocations
Displacement of bones from their normal positions at a joint.
Source: National Center for Biotechnology Information, U.S. National Library of Medicine
Additional Materials (10)
Sensitive content
This media may include sensitive content
Dislocated Finger
Right fifth phalanx dislocation
Image by Mdumont01/Wikimedia
Joint dislocation
X-ray of Dislocated Finger
Image by Mdumont01
Mandible (Normal vs Dislocated)
A medical illustration depicting a normal vs. dislocated mandible.
Image by BruceBlaus/Wikimedia
Dislocated hip replacement
A dislocated hip prosthesis.
Image by Bill Rhodes from Asheville/Wikimedia
Dislocated elbow
Lateral X ray of a dislocated right elbow
Image by James Heilman, MD
Joint-by-Joint Musculoskeletal Physical Exam: Hand and Wrist
Video by Ascension Via Christi/YouTube
Dislocation of the hip - Everything You Need To Know - Dr. Nabil Ebraheim
Video by nabil ebraheim/YouTube
Finger Dislocation & Metacarpal Block
Video by Larry Mellick/YouTube
Ankle Fracture Dislocation Reduction
Video by Larry Mellick/YouTube
Dislocations Of The Finger - Everything You Need To Know - Dr. Nabil Ebraheim
Video by nabil ebraheim/YouTube
Sensitive content
This media may include sensitive content
Dislocated Finger
Mdumont01/Wikimedia
Joint dislocation
Mdumont01
Mandible (Normal vs Dislocated)
BruceBlaus/Wikimedia
Dislocated hip replacement
Bill Rhodes from Asheville/Wikimedia
Dislocated elbow
James Heilman, MD
8:32
Joint-by-Joint Musculoskeletal Physical Exam: Hand and Wrist
Ascension Via Christi/YouTube
11:48
Dislocation of the hip - Everything You Need To Know - Dr. Nabil Ebraheim
nabil ebraheim/YouTube
4:10
Finger Dislocation & Metacarpal Block
Larry Mellick/YouTube
3:52
Ankle Fracture Dislocation Reduction
Larry Mellick/YouTube
3:59
Dislocations Of The Finger - Everything You Need To Know - Dr. Nabil Ebraheim
nabil ebraheim/YouTube
Fractures
femoral fracture
Image by SMART-Servier Medical Art
femoral fracture
Bone fractures - Thigh bone fracture - Fracture of femur
Image by SMART-Servier Medical Art
Fractures
A fracture is a break, usually in a bone. If the broken bone punctures the skin, it is called an open or compound fracture. Fractures commonly happen because of car accidents, falls, or sports injuries. Other causes are low bone density and osteoporosis, which cause weakening of the bones. Overuse can cause stress fractures, which are very small cracks in the bone.
Symptoms of a fracture are
Intense pain
Deformity - the limb looks out of place
Swelling, bruising, or tenderness around the injury
Numbness and tingling
Problems moving a limb
You need to get medical care right away for any fracture. An x-ray can tell if your bone is broken. You may need to wear a cast or splint. Sometimes you need surgery to put in plates, pins or screws to keep the bone in place.
Source: National Institute of Arthritis and Musculoskeletal and Skin Diseases
Additional Materials (26)
Mandibular fracture
Mandibular fracture
Image by Coronation Dental Specialty Group
Multiple fractures of the metacarpals (aka broken hand).
Multiple fractures of the metacarpals (aka broken hand).
Image by Garrulus from Galtür, Tirol
Facial Fractures
Video by Radiology Residency UM/JMH/YouTube
Breaking Down Hip Fractures
Video by Lee Health/YouTube
Risk Factors for Hip Fractures
Video by Lee Health/YouTube
Ankle Fractures
Video by sagaciousStudios/YouTube
Hip Fractures, Types and fixation - Everything You Need To Know - Dr. Nabil Ebraheim
Video by nabil ebraheim/YouTube
Finger and metacarpal Fractures - Everything You Need To Know - Dr. Nabil Ebraheim
Video by nabil ebraheim/YouTube
Wrist Fractures
Video by eMedTV/YouTube
How to Prevent Shin Splints and Stress Fractures
Video by NationwideChildrens/YouTube
Acetabular Fractures - Everything You Need To Know - Dr. Nabil Ebraheim
Video by nabil ebraheim/YouTube
Scaphoid Fractures
Video by Dartmouth-Hitchcock/YouTube
Scaphoid Fractures Blood Supply - Everything You Need To Know - Dr. Nabil Ebraheim
Video by nabil ebraheim/YouTube
Ankle Fractures , Clinical Examination - Everything You Need To Know - Dr. Nabil Ebraheim
Video by nabil ebraheim/YouTube
Spinal Compression Fracture Symptoms
Video by Age2B/YouTube
Spinal Compression Fracture Reasons
Video by Age2B/YouTube
Spinal compression fractures Anatomy
Video by Age2B/YouTube
Spinal fractures. Definition
Video by Age2B/YouTube
Treating Spinal Fractures with Kyphoplasty
Video by St. Mark's Hospital/YouTube
3 Facts about Pediatric Fractures
Video by OSMS/YouTube
Nasal Fractures & Children: Advice From an ENT
Video by St. Louis Children's Hospital/YouTube
Patellar Fractures - Everything You Need To Know - Dr. Nabil Ebraheim
Video by nabil ebraheim/YouTube
Ankle fracture / Fractures and its repair- Everything You Need To Know - Dr. Nabil Ebraheim
Video by nabil ebraheim/YouTube
Fractures, Types And Mechanisms - Everything You Need To Know - Dr. Nabil Ebraheim
Video by nabil ebraheim/YouTube
Metacarpal Fractures - Everything You Need To Know - Dr. Nabil Ebraheim
Video by nabil ebraheim/YouTube
facial fractures 3D reconstruction
Video by DrER.tv/YouTube
Mandibular fracture
Coronation Dental Specialty Group
Multiple fractures of the metacarpals (aka broken hand).
Garrulus from Galtür, Tirol
15:23
Facial Fractures
Radiology Residency UM/JMH/YouTube
1:37
Breaking Down Hip Fractures
Lee Health/YouTube
1:44
Risk Factors for Hip Fractures
Lee Health/YouTube
3:03
Ankle Fractures
sagaciousStudios/YouTube
3:51
Hip Fractures, Types and fixation - Everything You Need To Know - Dr. Nabil Ebraheim
nabil ebraheim/YouTube
5:05
Finger and metacarpal Fractures - Everything You Need To Know - Dr. Nabil Ebraheim
nabil ebraheim/YouTube
1:25
Wrist Fractures
eMedTV/YouTube
2:01
How to Prevent Shin Splints and Stress Fractures
NationwideChildrens/YouTube
3:56
Acetabular Fractures - Everything You Need To Know - Dr. Nabil Ebraheim
nabil ebraheim/YouTube
6:18
Scaphoid Fractures
Dartmouth-Hitchcock/YouTube
3:30
Scaphoid Fractures Blood Supply - Everything You Need To Know - Dr. Nabil Ebraheim
nabil ebraheim/YouTube
2:52
Ankle Fractures , Clinical Examination - Everything You Need To Know - Dr. Nabil Ebraheim
nabil ebraheim/YouTube
0:59
Spinal Compression Fracture Symptoms
Age2B/YouTube
1:01
Spinal Compression Fracture Reasons
Age2B/YouTube
0:59
Spinal compression fractures Anatomy
Age2B/YouTube
1:41
Spinal fractures. Definition
Age2B/YouTube
3:50
Treating Spinal Fractures with Kyphoplasty
St. Mark's Hospital/YouTube
3:47
3 Facts about Pediatric Fractures
OSMS/YouTube
1:54
Nasal Fractures & Children: Advice From an ENT
St. Louis Children's Hospital/YouTube
4:17
Patellar Fractures - Everything You Need To Know - Dr. Nabil Ebraheim
nabil ebraheim/YouTube
5:21
Ankle fracture / Fractures and its repair- Everything You Need To Know - Dr. Nabil Ebraheim
nabil ebraheim/YouTube
2:36
Fractures, Types And Mechanisms - Everything You Need To Know - Dr. Nabil Ebraheim
nabil ebraheim/YouTube
6:54
Metacarpal Fractures - Everything You Need To Know - Dr. Nabil Ebraheim
nabil ebraheim/YouTube
2:27
facial fractures 3D reconstruction
DrER.tv/YouTube
Sprains and Strains
Build Better Bones
Image by TheVisualMD
Build Better Bones
Your muscles can't make a move without your skeleton's support. Weight-bearing exercise stimulates the cells that grow new bone tissue. Regular exercise helps prevent bone loss, which can lead to the brittle-bone disease osteoporosis. Tendons and ligaments, the collagen-rich connective tissues that connect your bones and attach muscles to bones, are vital to keeping your frame strong.
Image by TheVisualMD
Sprains and Strains
A sprain is a stretched or torn ligament. Ligaments are tissues that connect bones at a joint. Falling, twisting, or getting hit can all cause a sprain. Ankle and wrist sprains are common. Symptoms include pain, swelling, bruising, and being unable to move your joint. You might feel a pop or tear when the injury happens.
A strain is a stretched or torn muscle or tendon. Tendons are tissues that connect muscle to bone. Twisting or pulling these tissues can cause a strain. Strains can happen suddenly or develop over time. Back and hamstring muscle strains are common. Many people get strains playing sports. Symptoms include pain, muscle spasms, swelling, and trouble moving the muscle.
At first, treatment of both sprains and strains usually involves resting the injured area, icing it, wearing a bandage or device that compresses the area, and medicines. Later treatment might include exercise and physical therapy.
Source: NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases
Additional Materials (20)
3D medical animation showing torn muscle fibers.
3D medical animation still showing tearing of muscle fibers.
Image by Scientific Animations, Inc.
sprain vs strains
Video by DrER.tv/YouTube
Wrist Ligament Sprain - Mayo Clinic
Video by Mayo Clinic/YouTube
Wrist Sprain: Injury to the Scapholunate Ligament
Video by Mayo Clinic/YouTube
Top 7 MCL Sprain Treatments - Ask Doctor Jo
Video by AskDoctorJo/YouTube
Knee sprain or ACL injury: How to tell the difference
Video by LifespanHealthSystem/YouTube
Can you walk on an ankle sprain?
Video by Mount Sinai Health System/YouTube
Ankle Pain, ankle ligaments sprain - Everything You Need To Know - Dr. Nabil Ebraheim
Video by nabil ebraheim/YouTube
Knee Sprain
Video by U of U Health/YouTube
Ankle sprain: how to heal as fast as possible
Video by Top Doctors UK/YouTube
What to do if an ankle sprain isn’t getting any better
Video by Top Doctors UK/YouTube
Child First Aid: Try first aid first for a sprain or strain
Video by British Red Cross/YouTube
Basic First Aid : How to Treat a Knee Sprain
Video by eHow/YouTube
How to treat a knee sprain | A Episode 61
Video by Pain Relief Expert/YouTube
Knee Injuries 101 (Health Short)
Video by Healthguru/YouTube
How to Heal a Sprained Ankle
Video by Howcast/YouTube
How to Treat a Sprained Ankle
Video by LIVESTRONG.COM/YouTube
Common Conditions Of The Thumb - Everything You Need To Know - Dr. Nabil Ebraheim
Video by nabil ebraheim/YouTube
Common Sports Injuries in Teens
Video by Children's Healthcare of Atlanta/YouTube
First Aid Tips : How to Treat a Jammed Finger or Toe
Video by eHow/YouTube
3D medical animation showing torn muscle fibers.
Scientific Animations, Inc.
4:21
sprain vs strains
DrER.tv/YouTube
3:58
Wrist Ligament Sprain - Mayo Clinic
Mayo Clinic/YouTube
4:23
Wrist Sprain: Injury to the Scapholunate Ligament
Mayo Clinic/YouTube
13:03
Top 7 MCL Sprain Treatments - Ask Doctor Jo
AskDoctorJo/YouTube
0:38
Knee sprain or ACL injury: How to tell the difference
LifespanHealthSystem/YouTube
1:18
Can you walk on an ankle sprain?
Mount Sinai Health System/YouTube
6:39
Ankle Pain, ankle ligaments sprain - Everything You Need To Know - Dr. Nabil Ebraheim
nabil ebraheim/YouTube
1:10
Knee Sprain
U of U Health/YouTube
1:38
Ankle sprain: how to heal as fast as possible
Top Doctors UK/YouTube
1:24
What to do if an ankle sprain isn’t getting any better
Top Doctors UK/YouTube
1:10
Child First Aid: Try first aid first for a sprain or strain
British Red Cross/YouTube
2:03
Basic First Aid : How to Treat a Knee Sprain
eHow/YouTube
2:31
How to treat a knee sprain | A Episode 61
Pain Relief Expert/YouTube
1:02
Knee Injuries 101 (Health Short)
Healthguru/YouTube
1:44
How to Heal a Sprained Ankle
Howcast/YouTube
2:42
How to Treat a Sprained Ankle
LIVESTRONG.COM/YouTube
4:32
Common Conditions Of The Thumb - Everything You Need To Know - Dr. Nabil Ebraheim
nabil ebraheim/YouTube
1:05
Common Sports Injuries in Teens
Children's Healthcare of Atlanta/YouTube
2:24
First Aid Tips : How to Treat a Jammed Finger or Toe
eHow/YouTube
Physical trauma
Whole-body projectional radiograph in a major trauma case, showing bilateral femur fractures
Image by Dimitrios S Evangelopoulos, Simone Deyle, Heinz Zimmermann and Aristomenis K Exadaktylos
Whole-body projectional radiograph in a major trauma case, showing bilateral femur fractures
Whole-body projectional radiograph in a major trauma case, showing bilateral femur fractures
Image by Dimitrios S Evangelopoulos, Simone Deyle, Heinz Zimmermann and Aristomenis K Exadaktylos
Physical Trauma Fact Sheet
What is physical trauma?
Physical trauma is a serious injury to the body. Two main types of physical trauma are:
Blunt force trauma—when an object or force strikes the body, often causing concussions, deep cuts, or broken bones.
Penetrating trauma—when an object pierces the skin or body, usually creating an open wound.
Surgery can also cause physical trauma, sometimes called a controlled injury.
Psychological trauma is an emotional or psychological injury. It usually results from an extremely stressful or life-threatening situation.
How has basic research improved trauma patient care?
Research on how the body responds to trauma has led to advances in the following areas:
Fluid replacement, such as saline solution for dehydration, and blood or blood substitutes for blood loss
Wound cleaning
Infection control
Nutrition support, such as vitamins that support wound healing
This means people who might have died from infection or blood loss before these advances have a better chance at survival today.
What are researchers learning about how the body responds to major trauma?
Researchers are making important discoveries about how the body responds to trauma. For example:
Research reveals that inflammation plays critical and complex roles after injury. It is needed for healing. But it can also lead to many life-threatening complications.
Studies of gene activity show that severe injury alters a large number of genes. By taking a close look at these changes, scientists can better understand how the body responds to trauma in the short and long term. It might also point to new treatment strategies.
Scientists have found links between the brain and the system that controls inflammation throughout the body. This work is leading to new treatments, including a way to stimulate the left vagus nerve—part of a pair of nerves that run from the brainstem through the neck and down to each side of the chest and abdomen—to control inflammation.
Internal organs often suffer damage after a serious injury. When faced with a life-threatening injury, the body redirects blood to try to save the brain and heart. This may rob the intestines and lungs of oxygen and other vital substances. Doctors can give the patient blood and other fluids to prevent damage to other organs.
Increasingly, researchers and doctors exchange ideas on new ways to treat severely injured patients.
What is on the horizon for trauma research supported by the National Institute of General Medical Sciences (NIGMS)?
NIGMS-funded research is directed toward an improved understanding of immediate as well as prolonged total body response to injury. This includes the following areas:
Researchers hope to find specific genes or proteins that they could measure to better predict outcomes and guide doctors to the best treatments for each patient.
Advances in wound care, including lab-grown cells, promise to speed healing. They may also allow a greater return to function and less scarring.
Continued testing of experimental approaches will bring new treatments. This means patients will have fewer complications, and more of them will survive.
Source: National Institute of General Medical Sciences (NIGMS)
Symptoms & Risk Factors for thrombosis and embolism
Image by TheVisualMD
Plan Ahead for Illness or Injuries During Your Trip
Plan ahead for illnesses, injuries, or other medical issues
Travel Health and Medical Evacuation Insurance
Travelers are responsible for hospital and other medical expenses incurred during their trip.
Check your health insurance plan to see if they will cover your health needs abroad.
Think about purchasing additional health insurance for your trip if your health insurance does not cover you while you are traveling.
Consider purchasing medical evacuation insurance. This kind of insurance will cover the cost of transporting you to other parts of a country or outside the country if you are seriously ill or injured.
Be prepared to pay out of pocket at the time you receive any medical services while traveling, even if you do have insurance.
Be Prepared for Illness Before and During Travel
It is a good idea to know beforehand the signs and symptoms of illness. This will prepare you to recognize these symptoms so that you can take action quickly while on your trip. CDC defines an ill traveler as a person who has one or more of the following symptoms:
Appearing obviously sick (e.g., severe headache, weakness, skin or eyes turning yellow)
Fever of 100° F (38° C) or greater
Skin rash
Shortness of breath or difficulty breathing
Severe cough that does not go away
Confusion, especially if it has just started
Bruising or bleeding (without previous injury)
Diarrhea that does not go away
Vomiting that does not go away (other than motion sickness)
If you have any of these symptoms while you are still at home, you should talk to your doctor before traveling.
1. Blood Clots (Deep Vein Thrombosis)
Airplane travel, especially flights longer than 8 hours, may increase the risk for blood clots, also known as Deep Vein Thrombosis/Pulmonary Embolism (DVT/PE).
You are at increased risk for DVT/PE if you:
Have had DVT/PE in the past,
Have had recent surgery (especially abdominal or orthopedic surgery),
Are pregnant,
Are a smoker,
Are taking birth control pills or hormone replacement therapy, or
Have cancer, restricted movement, or a blood-clotting problem.
If you have any of these conditions, talk to your doctor before traveling. People at higher risk for DVT/PE may be prescribed medication during travel.
To prevent DVT/PE during flight:
Stay hydrated
Wear loose-fitting clothing
Make an effort to walk and stretch your legs and arms at least once an hour
Your doctor may recommend that you wear special stockings that reduce leg swelling and encourage blood flow
2. Oxygen Levels in Flight
The air pressure in flight is lower than that at sea level. This lowers the amount of oxygen carried in the blood. Most healthy travelers will not notice these changes. However, passengers with certain medical conditions, particularly heart and lung diseases and blood disorders, such as anemia, may not be able to tolerate this reduced oxygen level. If you are concerned about needing more oxygen, talk with your doctor and the airline a few days before your trip to arrange for additional oxygen during flight.
Source: Centers for Disease Control and Prevention (CDC)
Additional Materials (5)
What Are the Signs and Symptoms of Pulmonary Embolism?
Deep Vein Thrombosis
Image by BruceBlaus
A case of phlegmasia cerulea dolens in the left leg
A case of phlegmasia cerulea dolens in the left leg
Image by James Heilman, MD
Sensitive content
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Prothrombin Time (PT): Deep Vein Thrombosis (DVT)
Deep vein thrombosis, or DVT, is a blood clot that forms in a vein deep in the body, typically the lower leg or thigh. If such clots travel to the lungs, they can cause pulmonary embolisms, which can damage tissue and impair the lungs' ability to supply oxygen to the body. Although anyone can develop DVT, such clots are often associated with prolonged bed rest, long periods of sitting in a cramped position, old age, or blood clotting disorders. Obesity, surgery, pregnancy, heart failure, cancer, smoking, and being tall can also elevate risk.
Image by TheVisualMD
Warfarin tablets
Warfarin tablets, 5, 3 and 1mg, photo by Gonegonegone, taken this date. Pink = 5mg, blue = 3mg, brown = 1mg.
Image by Gonegonegone at English Wikipedia
Travel Health and Safety
Video by NEJMvideo/YouTube
What Are the Signs and Symptoms of Pulmonary Embolism?
BruceBlaus
A case of phlegmasia cerulea dolens in the left leg
James Heilman, MD
Sensitive content
This media may include sensitive content
Prothrombin Time (PT): Deep Vein Thrombosis (DVT)
TheVisualMD
Warfarin tablets
Gonegonegone at English Wikipedia
1:58
Travel Health and Safety
NEJMvideo/YouTube
Tissue Injury and Aging
3D Cross-section showing skin tone becoming darker due to the production of more melanin to overcome the damage of melanin caused by sun tanning.
Image by Scientific Animations, Inc.
3D Cross-section showing skin tone becoming darker due to the production of more melanin to overcome the damage of melanin caused by sun tanning.
Image by Scientific Animations, Inc.
Tissue Injury and Aging
Tissues of all types are vulnerable to injury and, inevitably, aging. In the former case, understanding how tissues respond to damage can guide strategies to aid repair. In the latter case, understanding the impact of aging can help in the search for ways to diminish its effects.
Tissue Injury and Repair
Inflammation is the standard, initial response of the body to injury. Whether biological, chemical, physical, or radiation burns, all injuries lead to the same sequence of physiological events. Inflammation limits the extent of injury, partially or fully eliminates the cause of injury, and initiates repair and regeneration of damaged tissue. Necrosis, or accidental cell death, causes inflammation. Apoptosis is programmed cell death, a normal step-by-step process that destroys cells no longer needed by the body. By mechanisms still under investigation, apoptosis does not initiate the inflammatory response. Acute inflammation resolves over time by the healing of tissue. If inflammation persists, it becomes chronic and leads to diseased conditions. Arthritis and tuberculosis are examples of chronic inflammation. The suffix “-itis” denotes inflammation of a specific organ or type, for example, peritonitis is the inflammation of the peritoneum, and meningitis refers to the inflammation of the meninges, the tough membranes that surround the central nervous system
The four cardinal signs of inflammation—redness, swelling, pain, and local heat—were first recorded in antiquity. Cornelius Celsus is credited with documenting these signs during the days of the Roman Empire, as early as the first century AD. A fifth sign, loss of function, may also accompany inflammation.
Upon tissue injury, damaged cells release inflammatory chemical signals that evoke local vasodilation, the widening of the blood vessels. Increased blood flow results in apparent redness and heat. In response to injury, mast cells present in tissue degranulate, releasing the potent vasodilator histamine. Increased blood flow and inflammatory mediators recruit white blood cells to the site of inflammation. The endothelium lining the local blood vessel becomes “leaky” under the influence of histamine and other inflammatory mediators allowing neutrophils, macrophages, and fluid to move from the blood into the interstitial tissue spaces. The excess liquid in tissue causes swelling, more properly called edema. The swollen tissues squeezing pain receptors cause the sensation of pain. Prostaglandins released from injured cells also activate pain neurons. Non-steroidal anti-inflammatory drugs (NSAIDs) reduce pain because they inhibit the synthesis of prostaglandins. High levels of NSAIDs reduce inflammation. Antihistamines decrease allergies by blocking histamine receptors and as a result the histamine response.
After containment of an injury, the tissue repair phase starts with removal of toxins and waste products. Clotting (coagulation) reduces blood loss from damaged blood vessels and forms a network of fibrin proteins that trap blood cells and bind the edges of the wound together. A scab forms when the clot dries, reducing the risk of infection. Sometimes a mixture of dead leukocytes and fluid called pus accumulates in the wound. As healing progresses, fibroblasts from the surrounding connective tissues replace the collagen and extracellular material lost by the injury. Angiogenesis, the growth of new blood vessels, results in vascularization of the new tissue known as granulation tissue. The clot retracts pulling the edges of the wound together, and it slowly dissolves as the tissue is repaired. When a large amount of granulation tissue forms and capillaries disappear, a pale scar is often visible in the healed area. A primary union describes the healing of a wound where the edges are close together. When there is a gaping wound, it takes longer to refill the area with cells and collagen. The process called secondary union occurs as the edges of the wound are pulled together by what is called wound contraction. When a wound is more than one quarter of an inch deep, sutures (stitches) are recommended to promote a primary union and avoid the formation of a disfiguring scar. Regeneration is the addition of new cells of the same type as the ones that were injured.
Tissue Healing During wound repair, collagen fibers are laid down randomly by fibroblasts that move into repair the area.
Homeostatic Imbalances
Tissues and Cancer Cancer is a generic term for many diseases in which cells escape regulatory signals. Uncontrolled growth, invasion into adjacent tissues, and colonization of other organs, if not treated early enough, are its hallmarks. Health suffers when tumors “rob” blood supply from the “normal” organs.
A mutation is defined as a permanent change in the DNA of a cell. Epigenetic modifications, changes that do not affect the code of the DNA but alter how the DNA is decoded, are also known to generate abnormal cells. Alterations in the genetic material may be caused by environmental agents, infectious agents, or errors in the replication of DNA that accumulate with age. Many mutations do not cause any noticeable change in the functions of a cell. However, if the modification affects key proteins that have an impact on the cell’s ability to proliferate in an orderly fashion, the cell starts to divide abnormally. As changes in cells accumulate, they lose their ability to form regular tissues. A tumor, a mass of cells displaying abnormal architecture, forms in the tissue. Many tumors are benign, meaning they do not metastasize nor cause disease. A tumor becomes malignant, or cancerous, when it breaches the confines of its tissue, promotes angiogenesis, attracts the growth of capillaries, and metastasizes to other organs (image). The specific names of cancers reflect the tissue of origin. Cancers derived from epithelial cells are referred to as carcinomas. Cancer in myeloid tissue or blood cells form myelomas. Leukemias are cancers of white blood cells, whereas sarcomas derive from connective tissue. Cells in tumors differ both in structure and function. Some cells, called cancer stem cells, appear to be a subtype of cell responsible for uncontrolled growth. Recent research shows that contrary to what was previously assumed, tumors are not disorganized masses of cells, but have their own structures.
Cancer treatments vary depending on the disease’s type and stage. Traditional approaches, including surgery, radiation, chemotherapy, and hormonal therapy, aim to remove or kill rapidly dividing cancer cells, but these strategies have their limitations. Depending on a tumor’s location, for example, cancer surgeons may be unable to remove it. Radiation and chemotherapy are difficult, and it is often impossible to target only the cancer cells. The treatments inevitably destroy healthy tissue as well. To address this, researchers are working on pharmaceuticals that can target specific proteins implicated in cancer-associated molecular pathways.
Source: CNX OpenStax
Additional Materials (8)
Tissue Injury & Repair
Video by Anatomy and Physiology for Paramedics/YouTube
Wound Healing
A syncytium forms after wounding the Drosophila epithelium. The Molecular Biology of Wound Healing.
Image by The Molecular Biology of Wound Healing. PLoS Biol
Wound healing
Wound healing in process : Wound healing requires the action of stem cells. In mice that lack the Sept2/ARTS gene, stem cells involved in wound healing live longer and wounds heal faster and more thoroughly than in normal mice. This confocal microscopy image from a mouse lacking the Sept2/ARTS gene shows a tail wound in the process of healing. Cell nuclei are in blue. Red and orange mark hair follicle stem cells (hair follicle stem cells activate to cause hair regrowth, which indicates healing).
Image by Yaron Fuchs and Samara Brown, NIH
Sensitive content
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Wound Healing
3 June 2017 I injured myself hiking. Not sure how it happened, all I remember was heaving a heavy rock, slipping and then falling backwards into the deep water. As I fell I could see the injury on my shin and said to myself, "you're okay Raquel". Wrist was also injured, still (four months after) there’s a hematoma on my cheekbone. Was treating the wound with Neosporin but later a wound specialist gave me medicinal honey made with special pollen from New Zealand. The same doctor who stitched me up misdiagnosed skin infection (Cellulitis, note the purple marker on my leg in one of the photos) and gave me nasty antibiotics (Clindamycin), which made me feel sick. Had to hike a mile to the car in 103-degree weather, soaked my dress in the water, got to the car, ate an Ativan and drove to the hospital. Doctor asked if anything hurt, I said "no." Endorphins are powerful painkillers, I kept telling the nurses, "I'm lucky to be alive"! Took about 5 weeks to heal. Canyon is where I heaved the rock and slipped, over on the left, slightly out of the picture. It was the last pic I took that day.
Image by Raquel Baranow/Wikimedia
Wound healing in process
Wound healing requires the action of stem cells. In mice that lack the Sept2/ARTS gene, stem cells involved in wound healing live longer and wounds heal faster and more thoroughly than in normal mice. This confocal microscopy image from a mouse lacking the Sept2/ARTS gene shows a tail wound in the process of healing.
See more information in the press release from Rockefeller University (http://newswire.rockefeller.edu/2013/06/20/scientists-identify-gene-that-regulates-stem-cell-death-and-skin-regeneration/) and the article in Science (http://www.sciencemag.org/content/341/6143/286.abstract).Related to images 3497 and 3500.
Image by The photo was taken by Yaron Fuchs and Samara Brown. Fuchs is a postdoctoral fellow in Hermann Steller's lab and Brown is the lab's Research Technician III.
Wound healing in process
Wound healing requires the action of stem cells. In mice that lack the Sept2/ARTS gene, stem cells involved in wound healing live longer and wounds heal faster and more thoroughly than in normal mice. This confocal microscopy image from a mouse lacking the Sept2/ARTS gene shows a tail wound in the process of healing.
See more information in the press release from Rockefeller University (http://newswire.rockefeller.edu/2013/06/20/scientists-identify-gene-that-regulates-stem-cell-death-and-skin-regeneration/) and the article in Science (http://www.sciencemag.org/content/341/6143/286.abstract).Related to images 3498 and 3500.
Image by The photo was taken by Yaron Fuchs and Samara Brown. Fuchs is a postdoctoral fellow in Hermann Steller's lab and Brown is the lab's Research Technician III.
Wound healing
A fluorescence micrograph of cells in Drosophila larvae healing after a puncture wound. The arrow points to cells that have fused to form syncytia, and the arrowheads point to cells that are oriented to face the wound.
Image by Galko MJ, Krasnow MA
Tissue Healing
During wound repair, collagen fibers are laid down randomly by fibroblasts that move into repair the area.
Image by CNX Openstax
19:01
Tissue Injury & Repair
Anatomy and Physiology for Paramedics/YouTube
Wound Healing
The Molecular Biology of Wound Healing. PLoS Biol
Wound healing
Yaron Fuchs and Samara Brown, NIH
Sensitive content
This media may include sensitive content
Wound Healing
Raquel Baranow/Wikimedia
Wound healing in process
The photo was taken by Yaron Fuchs and Samara Brown. Fuchs is a postdoctoral fellow in Hermann Steller's lab and Brown is the lab's Research Technician III.
Wound healing in process
The photo was taken by Yaron Fuchs and Samara Brown. Fuchs is a postdoctoral fellow in Hermann Steller's lab and Brown is the lab's Research Technician III.
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Wounds and Injuries
An injury is damage to your body. It refers to harm caused by accidents, falls, hits, weapons, and more. In the U.S., millions of people injure themselves every year. Wounds are injuries that break the skin or other body tissues. They include cuts, bites, scrapes, scratches, and punctured skin. Get first aid tips and how to deal with different injuries.