The symptoms of cutis marmorata telangiectatica congenita (CMTC) may be different from infant to infant. Some may be more severely affected than others. Not everyone with CMTC will have the same symptoms.

CMTC is generally present at birth (congenital). Infants may be born with:

• Red or purple marbled looking patches of skin that don’t respond to warmth (cutis marmorata)
• Clusters of blood vessels visible under the skin (telangiectasia)
• Skin ulcers (open sores)
• Limb size discrepancy

The skin findings are usually seen in on part of the skin on the lower limbs, but can be on upper limbs or trunk, and less often, on the face. CMTC is usually confined to one part of the skin, on one limb, or on one side of the body. In rare cases, CMTC covers the whole body. The skin symptoms of CMTC typically get better over time and there are no known long-term complications of this condition.

CMTC can also be found associated with other birth defects or as part of other syndromes as well.

The exact cause of cutis marmorata telangiectatica congenita (CMTC) is not known. It is thought that a combination of factors may contribute to the development of this condition. These factors may include diet, viral infections, and genetic factors. In a few rare cases, CMTC may occasionally run in families.