Therapeutic Lifestyle Changes (TLC) to Lower Cholesterol
Need to lower your cholesterol? Learn how to make the lifestyle changes that will lower blood cholesterol and reduce your risk for heart disease.
Therapeutic Lifestyle Changes (TLC) To Lower Cholesterol
What Is the TLC Program?
You Are What You Eat
You Are What You Don't Eat, Too
Vitamin C
Vitamin D
Potassium
Lack of Vitamin A Can Affect Your Eyes
Lack of iron can affect your red blood cells
Lack of vitamin D can affect your bones
1
2
3
4
5
6
7
8
You Are/Aren't What You Eat
Interactive by TheVisualMD
You Are What You Eat
You Are What You Don't Eat, Too
Vitamin C
Vitamin D
Potassium
Lack of Vitamin A Can Affect Your Eyes
Lack of iron can affect your red blood cells
Lack of vitamin D can affect your bones
1
2
3
4
5
6
7
8
You Are/Aren't What You Eat
Protein, fat, and carbohydrates are macronutrients, foods that you eat in relatively large amounts. Vitamins and minerals are micronutrients. They're present in the food you eat in only tiny quantities, but they're still absolutely vital for good health. Your body needs them to carry out many important functions, from aiding eyesight to maintaining healthy bones. Micronutrients support normal growth and development and help cells and organs do their jobs. A diet that includes natural fats, a variety of meats, and whole vegetables provides you with all the vitamins and minerals you need.
Interactive by TheVisualMD
What Is the TLC Program?
The Therapeutic Lifestyle Changes, or TLC, Program is a three-part program created by the National Heart, Lung, and Blood Institute to improve cholesterol numbers. The TLC Program is well known for its diet plan, which has led many people to adopt a heart-healthy eating regimen.
The TLC Program combines diet, physical activity, and weight management to help lower high blood cholesterol and improve heart health. The Program’s step-by-step plan can lower LDL cholesterol (the “bad” cholesterol) and risks for metabolic disease, heart disease, and other serious conditions.
The program starts with a heart-healthy diet and physical activity, while controlling other risk factors for heart disease such as smoking and high blood pressure. As the program continues, LDL goals are created and monitored by you and your healthcare provider.
Source: National Heart, Lung, and Blood Institute (NHLBI)
Additional Materials (13)
Nutrition and Bone Health
Can you see what this man is made of? His musculature and skeleton are images from real medical scans. Muscles like that are built from turkey and tofu. Cantaloupe, packed with vitamin C and beta carotene, formed the eyes. His bones are strengthened by yogurt and spinach. Eating is a daily opportunity to choose new building blocks for a stronger, more healthful body. You cannot choose your genes. You cannot choose the experiences that have built the body you have now. But you can choose a salmon filet, knowing that the omega-3 fatty acids will help you avoid coronary heart disease and macular degeneration. You can reject the heart-threatening trans fats in many convenience foods for a more healthful monounsaturated fat, like olive or canola oil. Knowing what you are made of, and what nutrients you need to maintain balance, will be essential to building a life of health and wellness.
Image by TheVisualMD
Your Guide to Lowering Cholesterol With Therapeutic Lifestyle Changes (TLC)
Need to lower your cholesterol? TLC (therapeutic lifestyle changes) is a set of tools you can use to get results. This easy-to-read booklet is designed to help you make the lifestyle changes that will lower blood cholesterol and reduce your risk for heart disease. It explains how to follow the TLC diet (low in saturated fat, trans fat, and dietary cholesterol), increase physical activity, and manage weight for people whose cholesterol level is above their goal. The guide includes helpful lists and charts, sample menus, a 10-year coronary heart disease risk calculator, and many tips for success. Make TLC part of your program for heart health.
Document by National Heart, Lung, and Blood Institute (NHLBI)
Sweetness is Our Weakness
Regularly flooding your bloodstream with sugar takes a serious toll
Image by TheVisualMD
What Makes a Functional Food?
One of the hottest health topics in recent years has been research into specific foods that are believed to deliver a health-promoting or disease-preventing benefit above and beyond everyday nutrition. They are often referred to as “functional foods” meaning that they deliver more than just calories to burn for energy. There is no technical definition of a functional food, however, nor does the FDA recognize functional foods as a distinct category. And it is quite possible that all whole foods are “functional” in this sense if we knew everything there was to know about them.
Image by TheVisualMD
Cholesterol & Your Health: What You Need to Know
Unhealthy cholesterol levels can harm your heart health. This 6-page brochure will help you learn why cholesterol levels matter, what healthy cholesterol levels are, and what to do if you have high cholesterol.
Document by NHLBI
What is the TLC Diet and how does it benefit your heart health?
Video by HonorHealth/YouTube
Why is the Mediterranean diet good for your heart?
Video by British Heart Foundation/YouTube
TLC Diet presented by Debra Kirk RN
Video by Boulder Valley Care Network/YouTube
Cut your heart attack risk with these five lifestyle changes
Video by CBS Mornings/YouTube
Adding Nutrients to Nature
Image by TheVisualMD
Antioxidants are Heroes
Image by TheVisualMD
Does Heart Disease Run in Your Family? Familial Hypercholesterolemia
Recent data suggest that more than 1.3 million people (1 in 250) in the United States have FH and that many of them are undertreated, even when they know they have high cholesterol.
Image by Centers for Disease Control and Prevention (CDC)
Adding Nutrients to Nature
Image by TheVisualMD
Nutrition and Bone Health
TheVisualMD
Your Guide to Lowering Cholesterol With Therapeutic Lifestyle Changes (TLC)
National Heart, Lung, and Blood Institute (NHLBI)
Sweetness is Our Weakness
TheVisualMD
What Makes a Functional Food?
TheVisualMD
Cholesterol & Your Health: What You Need to Know
NHLBI
1:00
What is the TLC Diet and how does it benefit your heart health?
HonorHealth/YouTube
2:50
Why is the Mediterranean diet good for your heart?
British Heart Foundation/YouTube
1:07
TLC Diet presented by Debra Kirk RN
Boulder Valley Care Network/YouTube
2:19
Cut your heart attack risk with these five lifestyle changes
CBS Mornings/YouTube
Adding Nutrients to Nature
TheVisualMD
Antioxidants are Heroes
TheVisualMD
Does Heart Disease Run in Your Family? Familial Hypercholesterolemia
Centers for Disease Control and Prevention (CDC)
Adding Nutrients to Nature
TheVisualMD
What Is Blood Cholesterol?
Cholesterol is made by your own body
Image by TheVisualMD
Cholesterol is made by your own body
Cholesterol is made by your own body. It is also found in food products derived from animals. Cholesterol is used to make bile acids in the liver, necessary for fat digestion. Cholesterol is constantly transported in the bloodstream between the liver and all the body's tissues. HDL-cholesterol helps clear excess cholesterol from your body. LDL-cholesterol is ingested by cells in need of cholesterol. LDL particles of the Pattern A type are larger and less dense and may be harmless. LDL particles of the Pattern B type, however, are smaller and more dense and can penetrate through the lining of an artery and into its interior. Oxidized LDL particles (oxLDL) can cause major damage.
Image by TheVisualMD
What Is Blood Cholesterol?
Cholesterol is a waxy, fat-like substance that your body needs for good health, but in the right amounts. Unhealthy levels of cholesterol can lead to a condition called high blood cholesterol.
Cholesterol in your blood is carried on lipoproteins:
Low-density lipoprotein (LDL), sometimes called “bad” cholesterol
High-density lipoprotein (HDL), sometimes called “good” cholesterol.
High levels of “bad” LDL cholesterol cause plaque (fatty deposits) to build up in your blood vessels. This may lead to heart attack, stroke, or other health problems High levels of “good” HDL cholesterol may actually lower your risk for health problems. HDL cholesterol carries cholesterol and plaque buildup from your arteries to the liver, so it can be flushed out of the body.
Unhealthy cholesterol levels are often caused by lifestyle habits, such as unhealthy eating patterns, in combination with the genes that you inherit from your parents.
Routine blood tests can show whether your cholesterol levels are healthy. To help get your cholesterol levels into the healthy range, you may need heart-healthy lifestyle changes or medicines.
Source: National Heart, Lung, and Blood Institute (NHLBI)
Additional Materials (6)
Cholesterol
Cholesterol is a soft, waxy, fatty substance that's found naturally in every cell in your body. It's categorized as a lipid-that is, a fat, oil, or wax that won't dissolve in water. Cholesterol is necessary for your body's health because it helps to make cell membranes, digest fats, and produce vitamin D and various steroid hormones. Your bloodstream transports cholesterol throughout your body bound to water-soluble particles called lipoproteins.
Image by TheVisualMD
Learn About Blood Cholesterol
Video by NHLBI/YouTube
What is Cholesterol? What you Need to Know About #HDL, #LDL, Good and Bad #Cholesterol
Video by LetsGetChecked/YouTube
What cholesterol is and what cholesterol blood tests show
Video by Bupa Health UK/YouTube
Cholesterol Good and Bad
Video by The National Library of Medicine/YouTube
What is Cholesterol?
Video by American Heart Association/YouTube
Cholesterol
TheVisualMD
0:25
Learn About Blood Cholesterol
NHLBI/YouTube
10:25
What is Cholesterol? What you Need to Know About #HDL, #LDL, Good and Bad #Cholesterol
LetsGetChecked/YouTube
3:53
What cholesterol is and what cholesterol blood tests show
Bupa Health UK/YouTube
3:01
Cholesterol Good and Bad
The National Library of Medicine/YouTube
2:54
What is Cholesterol?
American Heart Association/YouTube
What Is Metabolic Syndrome?
Getting to the Heart of Things
Image by TheVisualMD
Getting to the Heart of Things
The cardiovascular system consists of the heart, the blood vessels, and the blood itself. Blood is mostly made up of plasma and red and white blood cells. But it contains many other substances as well, like platelets, hormones, and nutrients such as glucose. The cardiovascular system distributes these substances throughout the body as needed and collects waste products from your cells for elimination.
Image by TheVisualMD
What Is Metabolic Syndrome?
Metabolic syndrome is a group of conditions that together raise your risk of coronary heart disease, diabetes, stroke, and other serious health problems. Metabolic syndrome is also called insulin resistance syndrome.
You may have metabolic syndrome if you have three or more of the following conditions.
A large waistline: This is also called abdominal obesity or "having an apple shape." Extra fat in your stomach area is a bigger risk factor for heart disease than extra fat in other parts of your body.
High blood pressure: If your blood pressure rises and stays high for a long time, it can damage your heart and blood vessels. High blood pressure can also cause plaque, a waxy substance, to build up in your arteries. Plaque can cause heart and blood vessel diseases such as heart attack or stroke.
High blood sugar levels: This can damage your blood vessels and raise your risk of getting blood clots. Blood clots can cause heart and blood vessel diseases.
High blood triglycerides: Triglycerides are a type of fat found in your blood. High levels of triglycerides can raise your levels of LDL cholesterol, sometimes called bad cholesterol. This raises your risk of heart disease.
Low HDL cholesterol, sometimes called good cholesterol: Blood cholesterol levels are important for heart health. “Good” HDL cholesterol can help remove “bad” LDL cholesterol from your blood vessels. “Bad” LDL cholesterol can cause plaque buildup in your blood vessels.
Metabolic syndrome is common in the United States. About 1 in 3 adults have metabolic syndrome. The good news is that it is largely preventable. Knowing the risk factors and making healthy lifestyle changes can help you lower your chances of developing metabolic syndrome or the health problems it can cause.
Source: National Heart, Lung, and Blood Institute (NHLBI)
Additional Materials (24)
What is Metabolic Syndrome? (Syndrome X)
Video by healthery/YouTube
Healthbeat - Metabolic Syndrome
Video by KOAT/YouTube
Metabolic Syndrome
Video by Focus Medica/YouTube
Causes of Insulin Resistance: The Personal Fat Threshold
Video by Nourished by Science/YouTube
Metabolic Syndrome: A Risky Diagnosis
Video by Lee Health/YouTube
Do you have Metabolic Syndrome?
Video by Michigan Medicine/YouTube
How to Exercise & Diet Correctly for Your Body Type | Joanna Soh
Video by Joanna Soh Official/YouTube
Your 5 Keys to Diagnosing Metabolic Syndrome
Video by Lee Health/YouTube
Intermittent Fasting May Help Treat Metabolic Syndrome
Video by F. Perry Wilson, MD/YouTube
Patients With Isolated Metabolic Syndrome
Video by Mayo Proceedings/YouTube
Cardiorespiratory Fitness, Cardiometabolic Risk Factors, and Metabolic Syndrome
Video by Mayo Proceedings/YouTube
Jeff Volek, PhD -- Discussion on Ketogenic Diet for Dyslipidemia & Metabolic Syndrome
Video by Epigenix Foundation/YouTube
Metabolic Syndrome
Video by CNN/YouTube
Joslin Scientists Identify Process that Affects Fat Distribution and Metabolic Syndrome
Video by Joslin Diabetes Center/YouTube
thin-outside-fat-inside / thin-outside-fat-inside
TOFI - Thin on the Outside Fat on the inside
Fat-Fat "Fat on the Outside Thin on the Inside" (FOTI) image. shows 2 subjects the first fat fit with reduced amount of internal fat compared with an obese control.
Interactive by ImagingFat
Prof. Jeff Volek - 'The Art and Science of Low Carb Living: Cardio-Metabolic Benefits and Beyond'
Video by Low Carb Down Under/YouTube
Injecting Insulin Using a Syringe
Video by Covenant Health/YouTube
Blood Sugar Levels
Video by Khan Academy/YouTube
Understanding Type 2 Diabetes
Video by Animated Diabetes Patient/YouTube
How Insulin Gets Glucose Into a Cell
Video by FatIsNotYourFault/YouTube
Insulin Resistance
Video by Focus Medica/YouTube
Insulin Resistance in Type 2 Diabetes
Video by FSUMedMedia/YouTube
Visceral Fat, Insulin Resistance & Diabetes
Video by Metagenics Institute/YouTube
Are you a TOFI? Thin Outside, Fat Inside
Video by Kshamica MD/YouTube
3:08
What is Metabolic Syndrome? (Syndrome X)
healthery/YouTube
2:16
Healthbeat - Metabolic Syndrome
KOAT/YouTube
0:53
Metabolic Syndrome
Focus Medica/YouTube
38:17
Causes of Insulin Resistance: The Personal Fat Threshold
Nourished by Science/YouTube
1:40
Metabolic Syndrome: A Risky Diagnosis
Lee Health/YouTube
2:38
Do you have Metabolic Syndrome?
Michigan Medicine/YouTube
12:40
How to Exercise & Diet Correctly for Your Body Type | Joanna Soh
Joanna Soh Official/YouTube
1:35
Your 5 Keys to Diagnosing Metabolic Syndrome
Lee Health/YouTube
3:47
Intermittent Fasting May Help Treat Metabolic Syndrome
F. Perry Wilson, MD/YouTube
3:37
Patients With Isolated Metabolic Syndrome
Mayo Proceedings/YouTube
5:26
Cardiorespiratory Fitness, Cardiometabolic Risk Factors, and Metabolic Syndrome
Mayo Proceedings/YouTube
49:11
Jeff Volek, PhD -- Discussion on Ketogenic Diet for Dyslipidemia & Metabolic Syndrome
Epigenix Foundation/YouTube
2:17
Metabolic Syndrome
CNN/YouTube
2:42
Joslin Scientists Identify Process that Affects Fat Distribution and Metabolic Syndrome
Joslin Diabetes Center/YouTube
TOFI - Thin on the Outside Fat on the inside
ImagingFat
48:17
Prof. Jeff Volek - 'The Art and Science of Low Carb Living: Cardio-Metabolic Benefits and Beyond'
Low Carb Down Under/YouTube
5:39
Injecting Insulin Using a Syringe
Covenant Health/YouTube
8:55
Blood Sugar Levels
Khan Academy/YouTube
3:46
Understanding Type 2 Diabetes
Animated Diabetes Patient/YouTube
5:22
How Insulin Gets Glucose Into a Cell
FatIsNotYourFault/YouTube
0:46
Insulin Resistance
Focus Medica/YouTube
1:26
Insulin Resistance in Type 2 Diabetes
FSUMedMedia/YouTube
1:48
Visceral Fat, Insulin Resistance & Diabetes
Metagenics Institute/YouTube
9:02
Are you a TOFI? Thin Outside, Fat Inside
Kshamica MD/YouTube
Understand Your Risk for Heart Disease
Lipoprotein (a) or Lp(a), Heart Attack
Image by TheVisualMD
Lipoprotein (a) or Lp(a), Heart Attack
LDL, HDL and total cholesterol have become standard biomarkers for heart disease. And yet half of all people who suffer heart attacks have normal cholesterol levels. For that reason, researchers have looked for other biomarkers that might help identify people at risk for cardiovascular disease. Lp(a) is a lipoprotein that closely resembles LDL, and like LDL, elevated levels of Lp(a) are associated with a higher risk of heart disease. Unlike LDL, however, Lp(a) levels are believed to be largely genetic.
Image by TheVisualMD
Understand Your Risk for Heart Disease
The first step toward heart health is understanding your risk of heart disease. Your risk depends on many factors, some of which are changeable and others that are not. Risk factors are conditions or habits that make a person more likely to develop a disease. These risk factors may be different for each person.
Preventing heart disease starts with knowing what your risks factors are and what you can do to lower them.
Risk factors for heart disease
Have high blood pressure
Have high blood cholesterol
Have overweight or obesity
Have prediabetes or diabetes
Smoke
Do not get regular physical activity
Have a family history of early heart disease, for example if your father or brother was diagnosed before age 55, or your mother or sister was diagnosed before age 65
Have a history of preeclampsia, which is a sudden rise in blood pressure and too much protein in the urine during pregnancy
Have unhealthy eating behaviors
Are age 55 or older for women or age 45 or older for men
Each risk factor increases your chance of developing heart disease. The more risks you have, the higher your overall risk.
Some risk factors cannot be changed. These include your age, sex, and a family history of early heart disease. Many others can be modified. For example, being more physically active and eating healthy are important steps for your heart health. You can make the changes gradually, one at a time. But making them is very important.
Women and heart disease
Women generally get heart disease about 10 years later than men do, but it’s still women’s #1 killer. After menopause, women are more likely to get heart disease, in part because estrogen hormone levels drop. Women who have gone through early menopause, either naturally or because they have had a hysterectomy, are twice as likely to develop heart disease as women of the same age who have not gone through menopause. Middle age is also a time when women tend to develop other risk factors for heart disease, such as high blood pressure.
Preeclampsia, which is high blood pressure during pregnancy, raises your risk of developing coronary heart disease later in life. It is a risk factor that you can’t control. However, if you’ve had the condition, you should take extra care to monitor your blood pressure and try to lower other heart disease risk factors.
You and your healthcare provider: A heart-healthy partnership
Risk factors such as high blood pressure or cholesterol generally don’t have obvious signs or symptoms. A crucial step in determining your risk is to see your provider for a thorough checkup and risk assessment. Your provider may use a risk calculator to estimate your risk of having a heart attack, having a stroke, or dying from a heart or blood vessel disease in the next 10 years or throughout your life.
For example, the Atherosclerotic Cardiovascular Disease (ASCVD) Estimatore considers your cholesterol levels, age, sex, race, and blood pressure. It also factors in whether you smoke or take medicines to manage your high blood pressure or cholesterol.
Your provider can be an important partner in helping you set and reach goals for heart health. Ask about your risk for heart disease at your annual checkup. Since your risk can change over time, keep asking each year.
Questions to ask your provider at your annual checkup
What is my risk of developing heart disease?
What is my blood pressure? What does it mean for me, and what do I need to do about it?
What are my cholesterol numbers? What do they mean for me, and what do I need to do about them?
What is my body mass index (BMI) and waist measurement? Do I need to lose weight for my health?
What is my blood sugar level, and does it mean I’m at risk for diabetes?
What other screening tests for heart disease do I need? How often should I return for checkups for my heart health?
How can we work together to help me quit smoking?
How much physical activity do I need to help protect my heart?
What is a heart-healthy eating plan for me? Should I see a registered dietitian or qualified nutritionist to learn more about healthy eating?
How can I tell when I’m having a heart attack?
If you already are being treated for heart disease or heart disease risk factors, discuss your treatment plan with your provider. Ask questions if you do not understand something or need more information. You may want to write down questions before your appointment as well.
Questions to discuss about your heart disease prevention and treatment plan
How does my treatment compare with what is recommended in the latest guidelines?
How well is my treatment plan working for me?
Are my risk factors for heart disease in a good range or getting better?
If your provider recommends medicine or a medical procedure, ask about the benefits and risks.
Source: National Heart, Lung, and Blood Institute (NHLBI)
Additional Materials (13)
Risk Factors and Cardiovascular Disease
Risk factors increase the likelihood that you'll develop cardiovascular disease, and the more risk factors you have, the greater your chances of developing it. Fortunately, most of these risk factors are within your control, like high cholesterol and high blood pressure levels, being overweight, smoking, lack of exercise, overconsumption of alcohol, unmanaged diabetes, and stress. Factors you can't control include genetics and aging.
Image by TheVisualMD
Are You at Risk for Heart Disease?
Image by National Heart, Lung, and Blood Institute (NHLBI)
Connection between Gum Disease and Heart Disease
You may wonder if there is a connection between gum disease and heart disease. According to American Academy of Periodontology (AAP), there is a strong connection between worsened gum disease and heart disease. The study also tells that about 47% of American adults suffer from periodontal (gum) disease, and the number of people among them facing the risk of cardiovascular disorder development is also pretty much alarming.
A study by U.S. Centers for Disease Control and Prevention (CDC) tells that 64 million people in US suffer from gum disease. And this health conditions puts them at the risk of certain other health conditions which are not only bad but also life threatening. Gum disease has also been found to contribute in the development of other diseases such as stoke, osteoporosis in adults, and diabetes. Since there are a lot of health risks concerned with gum diseases, dentists suggest people to be proactive when it comes to maintaining oral health.
How to prevent gum infections and heart disease
Gum health has always been important, and it becomes even more important if the connection between gum infection and heart disease is proven right on a wide scale. Having that said, there are a few things that you can do to ensure better gum and heart health.
•The first thing to be taken into the account is oral hygiene. Therefore, proper brushing, flossing and use of alcohol-free mouthwash can help you get rid of the bacteria which can cause oral infections.
•If you use tobacco in any form, it’s the time to start working on quitting. When you chew or smoke tobacco, you essentially let your oral cavity to get exposed to the toxins which can result in oral dryness, irritation and damage at cellular level. Therefore, if you want to maintain your oral health while making sure that your teeth remain strong and gums remain intact, you need to quit the use of tobacco.
•If activity in your life is limited, it’s the time to get up and get moving. You can maintain your cardiovascular health with the help of light to moderate exercise on daily basis.
•When it comes to health of the body, diet is something which we can never overlook. There is no aspect of body health which cannot be covered with the help of better diet. The first thing you should consider in this regard is to switch to clean, fresh and organic foods. Fast foods are directly harmful for oral and cardiovascular health. On the other hand, organic and fresh foods contain nutrients which give your oral and cardiovascular health the necessary sustenance in direct way.
•We all know how bad the stress can be. Apart from the mental condition at the time of stress, it can also result in long term health irregularities. The reason is the hormonal disturbance which triggers mental and physical disturbance. Hence, you need to avoid stress in order to stay healthy. For that purpose, you can exercise, meditate or listen to your favorite soundtrack.
Image by Kory Ashmore
Heart Disease Prevention, Treatment & Screening: Emory Women's Heart Center
Video by Emory Healthcare/YouTube
High Cholesterol In 30s, 40s, Increases Later Risk Of Heart Disease
Video by Duke Health/YouTube
How to Lower Your Risk for Heart Disease | UPMC HealthBeat
Video by UPMC/YouTube
Know your Risk and Prevent Heart Disease
Video by NHLBI/YouTube
Risk Factors for Heart Disease: Cholesterol
Video by University of Ottawa Heart Institute/YouTube
Risk Factors for Heart Disease: Diabetes
Video by University of Ottawa Heart Institute/YouTube
Risk Factors for Heart Disease: Blood Pressure
Video by University of Ottawa Heart Institute/YouTube
How Smoking Raises Heart Disease Risk | Heart Disease
Video by Howcast/YouTube
5 Risk Factors for Heart Disease | Cedars-Sinai
Video by Cedars-Sinai/YouTube
Risk factors for coronary artery disease | Circulatory System and Disease | NCLEX-RN | Khan Academy
Video by khanacademymedicine/YouTube
Risk Factors and Cardiovascular Disease
TheVisualMD
Are You at Risk for Heart Disease?
National Heart, Lung, and Blood Institute (NHLBI)
Connection between Gum Disease and Heart Disease
Kory Ashmore
2:43
Heart Disease Prevention, Treatment & Screening: Emory Women's Heart Center
Emory Healthcare/YouTube
1:32
High Cholesterol In 30s, 40s, Increases Later Risk Of Heart Disease
Duke Health/YouTube
0:47
How to Lower Your Risk for Heart Disease | UPMC HealthBeat
UPMC/YouTube
0:40
Know your Risk and Prevent Heart Disease
NHLBI/YouTube
3:29
Risk Factors for Heart Disease: Cholesterol
University of Ottawa Heart Institute/YouTube
3:52
Risk Factors for Heart Disease: Diabetes
University of Ottawa Heart Institute/YouTube
3:13
Risk Factors for Heart Disease: Blood Pressure
University of Ottawa Heart Institute/YouTube
1:34
How Smoking Raises Heart Disease Risk | Heart Disease
Howcast/YouTube
2:06
5 Risk Factors for Heart Disease | Cedars-Sinai
Cedars-Sinai/YouTube
12:34
Risk factors for coronary artery disease | Circulatory System and Disease | NCLEX-RN | Khan Academy
khanacademymedicine/YouTube
How to Lower Cholesterol with Diet
Lipids in Your Diet - Phospholipids, Cholesterol and Triglycerides
Image by TheVisualMD
Lipids in Your Diet - Phospholipids, Cholesterol and Triglycerides
Lipids in Your Diet - Phospholipids, Cholesterol and Triglycerides
Image by TheVisualMD
How to Lower Cholesterol with Diet
Cholesterol is a waxy, fat-like substance that's found in all the cells in the body. The liver makes cholesterol, and it is also in some foods, such as meat and dairy products.
Source: NIH: National Heart, Lung, and Blood Institute
What Is Cholesterol?
What Do My Cholesterol Results Mean?
Image by TheVisualMD
What Do My Cholesterol Results Mean?
Every complete medical checkup includes an analysis of the fats in your blood—mainly, your cholesterol levels. The balance of “good” and “bad” cholesterol in the blood is an important factor in your risk of cardiovascular disease. A combined cholesterol total of less than 200 milligrams per deciliter of blood is desirable. Even more important is having enough helpful HDL (high-density lipoprotein) cholesterol and not too much unstable LDL (low-density lipoprotein) cholesterol. You need fat. Your body uses it to build cells and hormones, and as a source of energy. Cholesterol's job is to bundle up with proteins and fat, in the form of triglycerides, to travel through the bloodstream to the places where fat is needed or stored. HDL molecules are good travelers, densely packed and stable. They can even tidy up potential blockages in the blood vessels as they pass through. LDL molecules, though, are more loosely put together. As they ramble through vessels, they can cause trouble by sticking to arteries' walls. If other cells, platelets and calcium build up at the site to create arterial plaque, the artery can become blocked. If plaque breaks free from the artery's wall, it could travel to the brain or heart, causing a stroke or heart attack. People with unhealthful cholesterol levels have no symptoms. A blood test is the only way to diagnose cholesterol problems. Yet, the Centers for Disease Control and Prevention finds that about 20% of U.S. adults have never had their cholesterol checked.
Image by TheVisualMD
What Is Cholesterol?
Your body needs some cholesterol to work properly. But if you have too much in your blood, it can stick to the walls of your arteries and narrow or even block them. This puts you at risk for coronary artery disease and other heart diseases.
Cholesterol travels through the blood on proteins called lipoproteins. One type, LDL, is sometimes called the "bad" cholesterol. A high LDL level leads to a buildup of cholesterol in your arteries. Another type, HDL, is sometimes called the "good" cholesterol. It carries cholesterol from other parts of your body back to your liver. Then your liver removes the cholesterol from your body.
Source: NIH: National Heart, Lung, and Blood Institute
Additional Materials (13)
Cholesterol is Crucial
Cholesterol is Cruicial : Cholesterol is abundant in cell membranes, where it provides structure and plays a role in cell signaling. Cholesterol forms most of a nerve cell`s myelin sheet, which speeds nerve impulses. Bile acids, produced by cholesterol in the liver, are essential for the absorption of fats from the intestine. Cholesterol is also necessary for the production of many hormones, including sex hormones such estrogen.
Image by TheVisualMD
Cholesterol - Causes, Symptoms and Treatment Options
Video by Rehealthify/YouTube
Cholesterol pathway
Cholesterol is essential for the maintenance of cell membranes, production of sex hormones, and absorption of key vitamins. We get cholesterol from the foods we eat (particularly red meat, dairy and eggs), but our livers produce most of it in a multi-step process (drugs like statins interrupt this process). Cholesterol is carried in the bloodstream in specialized packages called lipoproteins.
Image by TheVisualMD
Cholesterol in blood
High cholesterol levels. Computer artwork balls of cholesterol in a blood vessel. Cholesterol is a lipid, a fat-like substance. High blood levels of LDL (low-density lipoprotein) cholesterol compared to HDL (high-density lipoprotein) cholesterol are thought to raise the risk of atherosclerosis, the build-up of fatty deposits on artery walls. This is a major cause of heart attack and stroke.
Image by TLECOATL ZYANYA/Wikimedia
Total Cholesterol Rotation (HDL, LDL, and VLDL Molecules)
A test for total cholesterol is an overall measure of “good” as well as “bad” cholesterol. A lipoprotein (from the Greek lipos, for fat) is a fat-and-protein package that enables fats and cholesterol to move freely within the bloodstream (fats and blood, like oil and water, do not mix). Proteins and other components make up the outer shell of the lipoprotein; cholesterol and other fats are packed together inside. The size and density of the lipoprotein determines whether its cholesterol is classified as “good” or “bad.” This interactive features 3 lipoproteins: very high density lipoprotein (VLDL) which is the largest molecule, low-density lipoproteins (LDL) which is the medium-sized molecule, and high-density lipoproteins (HDL), which are the smallest and most dense.
Image by TheVisualMD
Cholesterol Sources with Anatomy
Cholesterol is made by your own body. It is also found in food products derived from animals. Cholesterol is used to make bile acids in the liver, necessary for fat digestion. Cholesterol is constantly transported in the bloodstream between the liver and all the body's tissues. HDL-cholesterol helps clear excess cholesterol from your body. LDL-cholesterol is ingested by cells in need of cholesterol. LDL particles of the Pattern A type are larger and less dense and may be harmless. LDL particles of the Pattern B type, however, are smaller and more dense and can penetrate through the lining of an artery and into its interior. Oxidized LDL particles (oxLDL) can cause major damage.
Image by TheVisualMD
Cholesterol - what is it and how can you prevent high cholesterol?
Video by Healthchanneltv / cherishyourhealthtv/YouTube
What Is HDL and LDL Cholesterol?
This video explains the difference between HDL and LDL cholesterol. It also reveals what may occur when there are high levels of LDL in the body.LDL may stick to an artery's inner wall causing the build up of plaque, affecting blood flow. When an artery stiffens and constricts, aneurysm, heart attack, and stroke can occur.
Image by TheVisualMD
Cholesterol Good and Bad
Video by The National Library of Medicine/YouTube
This browser does not support the video element.
Cholesterol & Atherosclerosis
While the term technically refers to any disease that affects the cardiovascular system (as used in MeSH), it is usually used to refer to those related to atherosclerosis (arterial disease). Everyone talks about high cholesterol and how bad it is for you. But why is it bad for you? Where does it come from? What's the difference between "good" and "bad" cholesterol? Take a journey inside the body and explore its vessels, as world-renowned doctors explain what cholesterol is all about and how it contributes to hardening of the arteries, a dangerous condition also known as atherosclerosis.
Video by TheVisualMD
Cholesterol, Heart and Liver
Cholesterol is essential for the maintenance of cell membranes, production of sex hormones, and absorption of key vitamins. We get cholesterol from the foods we eat, but our livers produce most of it. There are two main types of cholesterol particles found in the bloodstream: HDL (high-density lipoprotein, or \"good\" cholesterol); and LDL (low-density lipoprotein, or \"bad\" cholesterol). LDL is referred to as bad cholesterol because it leads to the formation of plaque deposits that can clog arteries and increase the risk of heart disease.
Image by TheVisualMD
What is Cholesterol? What you Need to Know About #HDL, #LDL, Good and Bad #Cholesterol
Video by LetsGetChecked/YouTube
Cholesterol is made by your own body
Cholesterol is made by your own body. It is also found in food products derived from animals. Cholesterol is used to make bile acids in the liver, necessary for fat digestion. Cholesterol is constantly transported in the bloodstream between the liver and all the body's tissues. HDL-cholesterol helps clear excess cholesterol from your body. LDL-cholesterol is ingested by cells in need of cholesterol. LDL particles of the Pattern A type are larger and less dense and may be harmless. LDL particles of the Pattern B type, however, are smaller and more dense and can penetrate through the lining of an artery and into its interior. Oxidized LDL particles (oxLDL) can cause major damage.
Image by TheVisualMD
Cholesterol is Crucial
TheVisualMD
1:33
Cholesterol - Causes, Symptoms and Treatment Options
Rehealthify/YouTube
Cholesterol pathway
TheVisualMD
Cholesterol in blood
TLECOATL ZYANYA/Wikimedia
Total Cholesterol Rotation (HDL, LDL, and VLDL Molecules)
TheVisualMD
Cholesterol Sources with Anatomy
TheVisualMD
2:42
Cholesterol - what is it and how can you prevent high cholesterol?
Healthchanneltv / cherishyourhealthtv/YouTube
What Is HDL and LDL Cholesterol?
TheVisualMD
3:01
Cholesterol Good and Bad
The National Library of Medicine/YouTube
3:08
Cholesterol & Atherosclerosis
TheVisualMD
Cholesterol, Heart and Liver
TheVisualMD
10:25
What is Cholesterol? What you Need to Know About #HDL, #LDL, Good and Bad #Cholesterol
LetsGetChecked/YouTube
Cholesterol is made by your own body
TheVisualMD
Treatment
Heart Healthy Lifestyle
Image by StoryMD
Heart Healthy Lifestyle
Image by StoryMD
What Are the Treatments for High Cholesterol? TLC Diet
The treatments for high cholesterol are heart-healthy lifestyle changes and medicines. The lifestyle changes include healthy eating, weight management, and regular physical activity.
Source: NIH: National Heart, Lung, and Blood Institute
How can I Lower
A Heart Healthy Lifestyle
Image by TheVisualMD
A Heart Healthy Lifestyle
Improving your health can lessen the symptoms of arrhythmia and other heart disorders. Underlying heart disease can increase the risk of developing arrhythmias. For these reasons, it makes sense to live a lifestyle that will keep your heart as healthy as possible.
Image by TheVisualMD
How Can I Lower Cholesterol with Diet?
Heart-healthy lifestyle changes include a diet to lower your cholesterol. The DASH eating plan is one example. Another is the Therapeutic Lifestyle Changes diet, which recommends that you
Choose healthier fats.You should limit both total fat and saturated fat. No more than 25 to 35% of your daily calories should come from dietary fats, and less than 7% of your daily calories should come from saturated fat. Depending upon how many calories you eat per day, here are the maximum amounts of fats that you should eat:
Calories per Day
Total Fat
Saturated Fat
1,500
42-58 grams
10 grams
2,000
56-78 grams
13 grams
2,500
69-97 grams
17 grams
Saturated fat is a bad fat because it raises your LDL (bad cholesterol) level more than anything else in your diet. It is found in some meats, dairy products, chocolate, baked goods, and deep-fried and processed foods.
Trans fat is another bad fat; it can raise your LDL and lower you HDL (good cholesterol). Trans fat is mostly in foods made with hydrogenated oils and fats, such as stick margarine, crackers, and french fries.
Instead of these bad fats, try healthier fats, such as lean meat, nuts, and unsaturated oils like canola, olive, and safflower oils.
Limit foods with cholesterol. If you are trying to lower your cholesterol, you should have less than 200 mg a day of cholesterol. Cholesterol is in foods of animal origin, such as liver and other organ meats, egg yolks, shrimp, and whole milk dairy products.
Eat plenty of soluble fiber. Foods high in soluble fiber help prevent your digestive tract from absorbing cholesterol. These foods include:
Whole-grain cereals such as oatmeal and oat bran
Fruits such as apples, bananas, oranges, pears, and prunes
Legumes such as kidney beans, lentils, chick peas, black-eyed peas, and lima beans
Eat lots of fruits and vegetables. A diet rich in fruits and vegetables can increase important cholesterol-lowering compounds in your diet. These compounds, called plant stanols or sterols, work like soluble fiber.
Eat fish that are high in omega-3 fatty acids. These acids won't lower your LDL level, but they may help raise your HDL level. They may also protect your heart from blood clots and inflammation and reduce your risk of heart attack. Fish that are a good source of omega-3 fatty acids include salmon, tuna (canned or fresh), and mackerel. Try to eat these fish two times a week.
Limit salt. You should try to limit the amount of sodium (salt) that you eat to no more than 2,300 milligrams (about 1 teaspoon of salt) a day. That includes all the sodium you eat, whether it was added in cooking or at the table, or already present in food products. Limiting salt won't lower your cholesterol, but it can lower your risk of heart diseases by helping to lower your blood pressure. You can reduce your sodium by instead choosing low-salt and "no added salt" foods and seasonings at the table or while cooking.
Limit alcohol. Alcohol adds extra calories, which can lead to weight gain. Being overweight can raise your LDL level and lower your HDL level. Too much alcohol can also increase your risk of heart diseases because it can raise your blood pressure and triglyceride level. One drink is a glass of wine, beer, or a small amount of hard liquor, and the recommendation is that:
Men should have no more than two drinks containing alcohol a day
Women should have no more than one drink containing alcohol a day
Nutrition labels can help you figure out how much fat, saturated fat, cholesterol, fiber, and sodium is in the foods that you buy.
Source: NIH: National Heart, Lung, and Blood Institute
Managing
Fiber Helps Lower Cholesterol
Image by TheVisualMD
Fiber Helps Lower Cholesterol
Image by TheVisualMD
Managing High Cholesterol
If you are concerned about your cholesterol, talk to your health care team about steps you can take to manage your cholesterol.
Take Your Medicine as Directed
If you take medicine to treat high low-density lipoprotein (LDL) cholesterol, heart disease, stroke, or diabetes, follow your health care team’s instructions carefully. Always ask questions if you don’t understand something. Never stop taking your medicine without first talking to your doctor, nurse, or pharmacist.
Make Healthy Lifestyle Changes
You can take steps to lower your high LDL cholesterol levels by making healthy changes to your lifestyle, such as choosing foods lower in saturated and trans fats and maintaining a healthy weight.
Talk with Your Health Care Team
You and your health care team can work together to prevent or treat diabetes and ensure that it doesn’t lead to high LDL cholesterol. Discuss your treatment plan regularly, and bring a list of questions to your appointments.
Check Your Cholesterol Regularly
You may need to have your cholesterol levels checked at least once every 4 to 6 years if you do not have heart disease. Some people need to get their cholesterol checked more often or less often. Talk with your health care team about the timeline that is best for you.
Source: Centers for Disease Control and Prevention (CDC)
Additional Materials (4)
Fiber Helps Lower Cholesterol
Image by TheVisualMD
Atherosclerosis & Cholesterol
Atherosclerosis & Cholesterol - While the term technically refers to any disease that affects the cardiovascular system (as used in MeSH), it is usually used to refer to those related to atherosclerosis (arterial disease).
Image by TheVisualMD
Fiber and Lowering Cholesterol
Take steps towards better health exploring why a diet rich in soluble fiber is a great way to help lower "bad" LDL cholesterol. Soluble fiber (found in oats, apples, beans, barley) acts like a cholesterol sponge, soaking up "bad" LDL cholesterol in the small intestine and lowering the risk of cardiovascular disease. It can also help regulate blood sugar and reduce the risk of type 2 diabetes.
Image by TheVisualMD
Soluble Fiber Helps Eliminate Cholesterol
This image shows a woman eating an apple - which contains soluble fiber. She has visible anatomy which focuses on the digestive tract. Soluble fiber acts like a cholesterol \"sponge\" by soaking up cholesterol-laden bile salts in the small intestine and eliminating these salts along with waste. Removing harmful cholesterol from the body decreases the amount of bad cholesterol collecting on the walls of the arteries, where it could increase the risk of heart attack and stroke. Soluble fiber can be found in a variety of grains, fruits, and vegetables.
Image by TheVisualMD
Fiber Helps Lower Cholesterol
TheVisualMD
Atherosclerosis & Cholesterol
TheVisualMD
Fiber and Lowering Cholesterol
TheVisualMD
Soluble Fiber Helps Eliminate Cholesterol
TheVisualMD
Fiber Helps Lower Cholesterol
Rotation
Clipping
1
2
Artichoke, MRI Scan - Eat foods high in Fiber and Nutrients
Interactive by TheVisualMD
Rotation
Clipping
1
2
Artichoke, MRI Scan - Eat foods high in Fiber and Nutrients
This 3D interactive allows you to rotate and clip into a MRI scan of a globe artichoke. Globe artichokes are a low-fat, low-starch vegetable high in insoluble fiber. They are also high in folic acid (notable for expectant women, since folic acid helps prevent neural-tube birth defects) and contain other nutrients including magnesium, chromium, manganese, potassium, phosphorous, iron, calcium, and Vitamin C.
Interactive by TheVisualMD
Fiber Helps Lower Cholesterol
You probably know that fiber is great for keeping you regular, but you might not know that it's good for you in other important ways. Just 10 grams or more of soluble fiber a day decreases your total LDL-cholesterol levels by slowing absorption of cholesterol. And fiber may even fight cancer. Fiber discourages the growth of unhealthy bacteria in intestines, which secrete cancer-causing enzymes. And it encourages the growth of health-promoting bacteria that crowd out the dangerous kind.
Foods with Fiber
Animal products contain no fiber, only plant products do. For people with high cholesterol, a switch to a low-fat, high-fiber diet often causes cholesterol levels to drop dramatically. Your best choices for fiber are
Whole grains (like oats, barley, brown rice, whole wheat)
Nuts and seeds
Beans, dried peas, lentils
Many vegetables (like broccoli, avocados, carrots, peppers, dark leafy greens)
Many fruits (like apples, bananas, berries, guava, dried fruits)
Soluble and Insoluble Fiber
There are two types of fiber, soluble and insoluble. Both are good for you. Insoluble doesn't dissolve in water but absorbs it, increasing bulk in your stool and shortening transit time through the intestine. Soluble fiber ferments in the large intestine and the end products of this fermentation are very beneficial for your health. What's more, soluble fiber acts like a sponge and soaks up LDL-cholesterol. It lowers your total cholesterol and LDL-cholesterol levels and your triglyceride levels as well. It even suppresses cholesterol synthesis by the liver.
Food sources of soluble fiber include oats, dried peas and beans, nuts, fruits and vegetables, barley, rye, flax, and psyllium husks. Food sources of insoluble fiber include fruits and vegetables, whole grains, brown rice, popcorn, wheat bran, and corn bran.
Source: TheVisualMD
Additional Materials (19)
Romain Lettuce, MRI Scan
This 3D interactive allows you to rotate and clip into a MRI scan of lettuce. Lettuce is a good source of Vitamin C, Vitamin K, and chlorophyll, which is the green pigment in the leaves. As a general rule, the darker the greens, the more nutritious the leaf. Romaine lettuce is especially dense in nutrients, providing Vitamins A, B1, B2, and C, folic acid (B9), manganese, and chromium. Lettuce is high in water and very low in calories.
Image by TheVisualMD
Broccoli, MRI Scan
Broccoli, MRI Scan
1
2
Broccoli, MRI Scan - Eat foods high in Fiber and Nutrients
This 3D interactive allows you to rotate and clip into a MRI scan of broccoli. Broccoli is widely hailed by nutritionists and other health experts. High in the antioxidants beta-carotene and Vitamin C, the vegetable has been linked to reduced risk of heart disease and several cancers (notably of the prostate). It is also known to prevent cataracts. Broccoli is a rich source of folic acid and calcium, and provides a healthy balance of insoluble-to-soluble fiber.
Interactive by TheVisualMD
Persimmon, MRI Scan (Rotation)
Persimmon, MRI Scan (Clipping)
1
2
Persimmon, MRI Scan
This 3D interactive allows you to rotate and clip into a MRI scan of a persimmon. The persimmon fruit resembles the tomato. It is low in calories (about 70 calories per 100g) and fats, and a rich source of dietary fiber. Fresh persimmons contain antioxidants including beta-carotene (a Vitamin A precursor), lycopene, lutein, zeaxanthin and cryptoxanthin. The fruits are also a very good source of Vitamin C, B-complex vitamins such as folic acid (B9), pyridoxine (B6), and thiamin (B1), and of the minerals potassium, manganese, copper, and phosphorus.
Interactive by TheVisualMD
Dragon Fruit, MRI Scan
Dragon Fruit, MRI Scan
1
2
Dragon Fruit, MRI Scan
This 3D interactive allows you to rotate and clip into a MRI scan of a dragon fruit. Dragon fruit, also known as pitaya, is a sweet fruit with an unusual appearance: green, pointed leaves similar to those on the crown of a pineapple rise from the red skin of the pitaya in a shape like flames, and the fruit`s white pulp is flecked with small black seeds (which are not typically consumed). Dragon fruit contains significant levels of Vitamin C, carotene, calcium, and B vitamins, in addition to other nutrients. The fruit is known for its antioxidant properties and can play a role in healthy digestion, immune function, healthy skin, and good night vision.
Interactive by TheVisualMD
Kiwi Fruit, MRI Scan
Kiwi Fruit, MRI Scan
1
2
Kiwi Fruit, MRI Scan
This 3D interactive allows you to rotate and clip into a MRI scan of kiwifruit. Originally from China -- but named for New Zealand`s national bird -- kiwifruit was first cultivated in the U.S. in the early 1900`s. According to a study at Rutgers University, the kiwi is, ounce for ounce, the most nutrient-dense fruit. Exceptionally high in Vitamin C, a half-cup serving of kiwi satisfies 140% the recommended DV. It provides 6% of the RDA for fiber, 10% for folic acid (B9) and Vitamin E, 8% for Copper, and 5.5% for calcium. Kiwi is high in fiber and virtually devoid of sodium or fat.
Interactive by TheVisualMD
Pomegranate MRI
Pomegranate MRI
1
2
Pomegranate MRI
Polyphenols, a type of antioxidant found in pomegranates, may reduce the risk of plaque buildup on artery walls.
Interactive by TheVisualMD
Psyllium seed husks
Macro zoom photograph of psyllium seed husks
Image by Bastique (Cary Bass)/Wikimedia
Psyllium seed husks (01)
Psyllium seed husks
Image by Rasbak/Wikimedia
Psyllium powder orange tast
Psyllium seed husks
Image by Rasbak/Wikimedia
Prevention & Lifestyle
Image by TheVisualMD
Fiber Helps Lower Cholesterol
Image by TheVisualMD
Metamucil ad
Title Metamucil Ad
Description An ad about Metamucil with 80% solulble fiber. NCI studies have shown that a high fiber, low fat diet could help reduce some kinds of cancer.Español:
Descripción Acerca de Metamulcil con 80% de fibra soluble.Estudios del NCI (Instituto Nacional del Cáncer USA) han encontrado antecedentes que una dieta alta en fibra y baja en grasa podría reducir algunos tipos de cancer. (Spanish)
Topics/Categories Food and Drink Historical -- Graphics
Type Color, Photo
Source National Cancer Institute
Image by Unknown photographer/Wikimedia
Soluble Fiber Helps Eliminate Cholesterol
This image shows a woman eating an apple - which contains soluble fiber. She has visible anatomy which focuses on the digestive tract. Soluble fiber acts like a cholesterol \"sponge\" by soaking up cholesterol-laden bile salts in the small intestine and eliminating these salts along with waste. Removing harmful cholesterol from the body decreases the amount of bad cholesterol collecting on the walls of the arteries, where it could increase the risk of heart attack and stroke. Soluble fiber can be found in a variety of grains, fruits, and vegetables.
Image by TheVisualMD
Fiber and Lowering Cholesterol
Take steps towards better health exploring why a diet rich in soluble fiber is a great way to help lower "bad" LDL cholesterol. Soluble fiber (found in oats, apples, beans, barley) acts like a cholesterol sponge, soaking up "bad" LDL cholesterol in the small intestine and lowering the risk of cardiovascular disease. It can also help regulate blood sugar and reduce the risk of type 2 diabetes.
Image by TheVisualMD
This browser does not support the video element.
Fiber and Lowering Cholesterol
Take steps towards better health exploring why a diet rich in soluble fiber is a great way to help lower "bad" LDL cholesterol. Soluble fiber (found in oats, apples, beans, barley) acts like a cholesterol sponge, soaking up "bad" LDL cholesterol in the small intestine and lowering the risk of cardiovascular disease. It can also help regulate blood sugar and reduce the risk of type 2 diabetes.
Video by TheVisualMD
Fiber Helps Lower Cholesterol
Image by TheVisualMD
How Fiber Lowers Cholesterol
Video by NutritionFacts.org/YouTube
5 Foods That Can Help Lower Cholesterol: Apples, Lentils, Avocados | TODAY
Video by TODAY/YouTube
How to eat a heart-healthy diet
Video by Sunnybrook Hospital/YouTube
Romain Lettuce, MRI Scan
TheVisualMD
Broccoli, MRI Scan - Eat foods high in Fiber and Nutrients
TheVisualMD
Persimmon, MRI Scan
TheVisualMD
Dragon Fruit, MRI Scan
TheVisualMD
Kiwi Fruit, MRI Scan
TheVisualMD
Pomegranate MRI
TheVisualMD
Psyllium seed husks
Bastique (Cary Bass)/Wikimedia
Psyllium seed husks (01)
Rasbak/Wikimedia
Psyllium powder orange tast
Rasbak/Wikimedia
Prevention & Lifestyle
TheVisualMD
Fiber Helps Lower Cholesterol
TheVisualMD
Metamucil ad
Unknown photographer/Wikimedia
Soluble Fiber Helps Eliminate Cholesterol
TheVisualMD
Fiber and Lowering Cholesterol
TheVisualMD
1:07
Fiber and Lowering Cholesterol
TheVisualMD
Fiber Helps Lower Cholesterol
TheVisualMD
2:43
How Fiber Lowers Cholesterol
NutritionFacts.org/YouTube
4:25
5 Foods That Can Help Lower Cholesterol: Apples, Lentils, Avocados | TODAY
TODAY/YouTube
10:59
How to eat a heart-healthy diet
Sunnybrook Hospital/YouTube
Familial Hypercholesterolemia
Two Sources of Cholesterol
Image by TheVisualMD
Two Sources of Cholesterol
Two Sources of Cholesterol: You Eat It & You Make It : We know that dietary fats are essential. But before your body can put these fats to use, they must somehow get from your digestive system into your cells. This isn`t as simple as it sounds because fats and blood, like oil and water, do not mix. The body gets around this basic chemistry problem by packaging fat and cholesterol into protein-covered particles that mix easily with blood and flow with it. The cholesterol helps to stabilize the particles, and the size and density of the lipoprotein (from the Greek lipos, for fat) determines whether its cholesterol is classified as "good" or "bad." High-density lipoproteins (HDL), also known as "good" cholesterol, are small, dense, protein-rich lipoproteins; low-density lipoproteins (LDL), also known as "bad" cholesterol, are larger, lighter, and fluffier lipoproteins that form plaque deposits and clog arteries.
Image by TheVisualMD
How Does Diet Affect the Blood Levels of LDL in People with Familial Hypercholesterolemia?
Diet affects blood levels of low-density lipoprotein (LDL) by influencing both the activity of LDL receptors and the synthesis of cholesterol in the liver. LDL receptors bind to LDL, which is the primary carrier of cholesterol in the blood. The receptors sit on the outer surface of many types of cells, where they pick up LDL circulating in the bloodstream and transport them into the cell. Once inside the cell, the LDL is broken down to release cholesterol. The cholesterol is then used by the cell, stored, or removed from the body. After the receptors drop off their "cargo," they are recycled back to the cell surface to pick up more LDL. LDL receptors therefore play a critical role in regulating the amount of cholesterol in the blood. They are particularly abundant in the liver, which is the organ responsible for removing most excess cholesterol from the body. The number of LDL receptors on the surface of liver cells determines how quickly cholesterol (in the form of LDL) is removed from the bloodstream.
The goal of dietary therapy in individuals with familial hypercholesterolemia (FH) is to increase the activity of LDL receptors while decreasing the synthesis of cholesterol in the liver. Two dietary factors have a major effect on LDL receptors: the amount of cholesterol in the diet and the amount of saturated fat in the diet. Both cholesterol and fat inhibit the activity of LDL receptors, and thus inhibit the removal of LDL from the blood by the liver. Dietary cholesterol and fat can also enhance or diminish the therapeutic effects of cholesterol-lowing drugs in individuals with FH.
Source: Genetic and Rare Diseases Information Center (GARD)
Additional Materials (1)
Prevention is Key
Plaque buildup and atherosclerosis may be slow in developing, but the consequences can be debilitating and often fatal. Fortunately, you have the power to keep your blood vessels healthy and clear by making wise choices in the ways in which you live, work, and play.
Image by TheVisualMD
Prevention is Key
TheVisualMD
Plant based
3D images of Vegetables
Image by TheVisualMD
3D images of Vegetables
3D images of Vegetables and quality nutrition
Image by TheVisualMD
How Can Plant-Based Eating Can Reap Rewards?
Vegetarians miss out on lots of foods. No grilled burgers or franks at picnics. No holiday turkey or fries cooked in animal fat. Strict vegetarians may even forego honey made by bees. But vegetarians also tend to miss out on major health problems that plague many Americans. They generally live longer than the rest of us, and they’re more likely to bypass heart-related and other ailments.
The fact is, eating a more plant-based diet can boost your health, whether you’re a vegetarian or not.
What is it about the vegetarian lifestyle that can protect your health? And are there risks to being vegetarian? NIH-funded researchers are looking for answers. They’re exploring the many ways that diet and other factors affect our health.
Vegetarian meals focus on fruits and vegetables, dried beans, whole grains, seeds and nuts. By some estimates, about 2% of the U.S. adult population follows this type of diet.
People have many reasons for becoming vegetarians. Some want to eat more healthy foods. Others have religious or economic reasons or are concerned about animal welfare. “Vegetarian diets are also more sustainable and environmentally sound than diets that rely heavily on meat, poultry and fish,” says NIH nutritionist Dr. Susan Krebs-Smith, who monitors trends in cancer risk factors.
Most people think of vegetarian diets as simply eating plant foods and not eating meat, poultry and fish. “But in fact, there are many different types of vegetarian diets,” Krebs-Smith explains. “Some are more restrictive than others.”
Strict vegetarians, or vegans, eat plant foods and reject all animal products—meat, poultry, fish, eggs, dairy and sometimes honey. Those who also eat dairy products are called lacto vegetarians. Vegetarians who eat both dairy and eggs are called lacto-ovo vegetarians.
Some vegetarians eat fish but not meat or poultry. They’re called pescatarians (pesce is Italian for fish).
“Then there are the so-called flexitarians, or semi-vegetarians. These are people who eat a mostly vegetarian diet, but they occasionally eat meat,” says Jody Engel, a nutritionist and registered dietitian at NIH. “They might say ‘I’m a vegetarian, but I need to eat my burgers every Sunday.’ People tend to follow their own rules, which is one reason why it’s hard for researchers to study vegetarians. There’s so much variance.”
Despite the different definitions, “there’s tremendous agreement among nutrition experts and health organizations that a more plant-based diet is beneficial, whether you’re a true vegetarian or not,” says Krebs-Smith. “Most Americans don’t eat enough fruit, vegetables, legumes or whole grains. There’s a huge consensus that eating more of these foods would be a good idea for everyone.”
Vegetarian diets tend to have fewer calories, lower levels of saturated fat and cholesterol, and more fiber, potassium and vitamin C than other eating patterns. Vegetarians tend to weigh less than meat-eaters, and to have lower cancer rates. “Evidence also suggests that a vegetarian diet is associated with a lower risk of death from certain heart diseases, and that those who follow a vegetarian diet tend to have lower LDL [“bad”] cholesterol levels,” says Engel.
In some cases, though, it’s unclear if certain health benefits come from plant-based eating or from the healthy lifestyle of most vegetarians. “Vegetarians are generally more physically active and have healthier habits than non-vegetarians. They also typically have a higher socioeconomic status, at least in the United States,” says Krebs-Smith.
To tease out the effects of diet, scientists have to conduct large, carefully controlled studies that account for other factors. One of the world’s largest studies of plant-based diets is now underway at Loma Linda University in California. Cardiologist Dr. Gary Fraser is leading an NIH-funded team of scientists to analyze data on 96,000 Seventh-day Adventists in all 50 states and in Canada. Members of this religious group have unique dietary habits and a generally healthy lifestyle.
Adventists are encouraged to follow a vegetarian diet, but about half the population sometimes eats meat. These variable eating patterns allow scientists to compare a wide range of dietary habits and look for links between diet and disease.
To date, the researchers have found that the closer people are to being vegetarian, the lower their risk of diabetes, high blood pressure and metabolic syndrome (a condition that raises your risk for heart disease and stroke). “The trend is almost like a stepladder, with the lowest risks for the strict vegetarians, then moving up for the lacto vegetarians and then the pescatarians and then the non-vegetarians,” Fraser explains. Earlier studies found that vegetarian Adventists also tend to live longer than both meat-eating Adventists and non-Adventists. The vegetarians also have less coronary heart disease and lower rates of some cancers.
Because vegetarians by definition don’t eat meat, some people jump to the conclusion that simply cutting meat from your diet will lead to health benefits. “But it’s actually more complicated than that,” says Fraser. “Differences in life expectancy and other health matters might be related to the extra fruits, vegetables, nuts and legumes—including soy—that vegetarians tend to eat. You can’t necessarily conclude it’s based on the absence of meat,” he says.
Experts generally agree that vegetarians who eat a wide variety of foods can readily meet all their body’s needs for nutrients. “At any stage of life, you should be able to eat a healthy diet by consuming vegetarian foods. But it does take a little planning,” says Rachel Fisher, a registered dietitian involved in nutrition research at NIH.
Vegetarians need to be sure they take in enough iron, calcium, zinc and vitamin B12. Studies show that most vegetarians do get enough, in part because so many cereals, breads and other foods are fortified with these nutrients. “Vegans in particular need to be certain to get enough vitamin B12 and omega-3 fatty acids,” says Fisher. Omega-3—found in fish, flax seed, walnuts and canola oil—is important for heart health and vision.
Some vegetarians take dietary supplements to make sure they’re getting everything they need. It’s a good idea to talk to a registered dietitian or other health professional if you’re a vegetarian or thinking of becoming one.
Whether you’re a vegetarian or not, Fisher says, you can benefit from the high fiber, low fat and rich nutrients of a vegetarian diet. “Vegetarian foods can be so delicious, and they’re so good for you,” she says.
Try using a variety of spices and herbs to make things interesting. And make sure not to overcook your vegetables, or they might lose some of their valuable nutrients.
Tips for a Vegetarian Diet
Meet protein needs by eating a variety of plant foods, nuts, eggs or dairy foods.
Snack on unsalted nuts and use them in salads or main dishes.
Vitamin B12 is naturally found only in animal products. Choose fortified foods such as cereals or soy products, or take a vitamin B12 supplement if you don’t eat animal products.
Get calcium from dairy products and calcium-fortified soy milk, breakfast cereals or orange juice.
Beans and peas have many nutrients and are recommended for everyone, vegetarians and non-vegetarians alike.
Source: NIH News in Health
Additional Materials (11)
Vegan meal, sweet potato, pizza, plant based
use as you wish
Image by Nitsan Simantov/Wikimedia
Plant-Based Dishes, Raw Food
Plant-Based Dishes, Raw Food
Image by Ella Olsson from Stockholm, Sweden/Wikimedia
Vegan friendly icon
Icone végan
Image by Peepal Farm Foundation/Wikimedia
Vegan Plate
Source:
Heike Englert, Sigrid Siebert: "Vegane Ernährung", UTB, Kapitel 6.1 "Das Modell des 'Veganen Tellers' - Empfehlungen zur Lebensmittelauswahl, ISBN 978-8463-4402-6, Google Books
The vegan food plate: A simple guide to healthy vegan nutrition
Created using: Category:Firefox_OS_Emoji
Image by Tischbeinahe/Wikimedia
Going Vegetarian Is A Healthy Choice
Video by CNN/YouTube
What If The World Went Vegetarian?
Video by AsapSCIENCE/YouTube
Vegan meal, hummus, salad, veggie fingers, plant based
use as you wish
Image by Nitsan Simantov/Wikimedia
Vegan meal, onion curry, rice, peas, plant based
Use as you wish
Image by Nitsan Simantov/Wikimedia
Vegan meal, tortilla wrap, plant based
Use as you wish
Image by Nitsan Simantov/Wikimedia
Meal prep food container (43991880552)
Ready made plant-based food in a meal prep container. Trying to get better at planning my meals ahead of time
Image by Ella Olsson from Stockholm, Sweden/Wikimedia
Rotation
Clipping
1
2
Artichoke, MRI Scan - Eat foods high in Fiber and Nutrients
This 3D interactive allows you to rotate and clip into a MRI scan of a globe artichoke. Globe artichokes are a low-fat, low-starch vegetable high in insoluble fiber. They are also high in folic acid (notable for expectant women, since folic acid helps prevent neural-tube birth defects) and contain other nutrients including magnesium, chromium, manganese, potassium, phosphorous, iron, calcium, and Vitamin C.
Interactive by TheVisualMD
Vegan meal, sweet potato, pizza, plant based
Nitsan Simantov/Wikimedia
Plant-Based Dishes, Raw Food
Ella Olsson from Stockholm, Sweden/Wikimedia
Vegan friendly icon
Peepal Farm Foundation/Wikimedia
Vegan Plate
Tischbeinahe/Wikimedia
2:56
Going Vegetarian Is A Healthy Choice
CNN/YouTube
3:47
What If The World Went Vegetarian?
AsapSCIENCE/YouTube
Vegan meal, hummus, salad, veggie fingers, plant based
Nitsan Simantov/Wikimedia
Vegan meal, onion curry, rice, peas, plant based
Nitsan Simantov/Wikimedia
Vegan meal, tortilla wrap, plant based
Nitsan Simantov/Wikimedia
Meal prep food container (43991880552)
Ella Olsson from Stockholm, Sweden/Wikimedia
Artichoke, MRI Scan - Eat foods high in Fiber and Nutrients
TheVisualMD
Nutrition
Mother Infant Nutrition
Image by TheVisualMD
Mother Infant Nutrition
Mother Infant Nutrition
Image by TheVisualMD
Nutrition
Food provides the energy and nutrients you need to be healthy. Nutrients include proteins, carbohydrates, fats, vitamins, minerals, and water.
Healthy eating is not hard. The key is to
Eat a variety of foods, including vegetables, fruits, and whole-grain products
Eat lean meats, poultry, fish, beans, and low-fat dairy products
Drink lots of water
Limit salt, sugar, alcohol, saturated fat, and trans fat in your diet
Saturated fats are usually fats that come from animals. Look for trans fat on the labels of processed foods, margarines, and shortenings.
Source: Centers for Disease Control and Prevention (CDC)
Additional Materials (14)
Basket of Nutrients
Basket of Nutrients
Image by TheVisualMD / Gerhard G.
This browser does not support the video element.
What are Vitamins and Minerals?
At the foundation of every healthy diet is an appropriate balance of vitamins and minerals. Provided by nature in the plants and meats we consume, vitamins and minerals are critical to growth and development at every stage of life. Once absorbed into the bloodstream, molecules of these nutrients help the body complete a remarkable range of critical functions.
Video by TheVisualMD
This browser does not support the video element.
Salt & Other Minerals
Though minerals are themselves inactive, they are put to work in every tissue, every organ, and every system of the human body. Dietary minerals are critical for other life forms, too; they are required for the animation and well being of every living organism, from plankton in the sea to the houseplant on your window sill. Learn why minerals are an essential part of your diet and body. We also spotlight sodium, a good mineral turned bad, and how you can control the amount of sodium you consume in your diet.
Video by TheVisualMD
Vitamins and Minerals in Aloe Vera - Health Benefits of Aloe Vera
Video by Foods4Health/YouTube
This browser does not support the video element.
Functional Foods
Functional foods are specific foods that are believed to deliver a health-promoting or disease-preventing benefit above and beyond everyday nutrition, meaning that they deliver more than just calories to burn for energy. There is no technical definition of a functional food, however, nor does the FDA recognize functional foods as a distinct category. While many functional foods are rich in vitamins, the recent research and consumer interest in these "superfoods" is focused on components that are not categorized as vitamins. They are not strictly necessary, but are believed to play key roles in optimal health and wellness. Explore what makes a food "functional" and increase your understanding of antioxidants and free radicals.
Video by TheVisualMD
This browser does not support the video element.
Nutritionist Chrissy Wellington, MS on whole foods
Nutritionist Chrissy Wellington, MS on whole foods
Video by TheVisualMD
This browser does not support the video element.
Nutritionist Chrissy Wellington, MS on fresh foods
Nutritionist Chrissy Wellington, MS on fresh foods
According to the USDA, "Organic meat, poultry, eggs, and dairy products come from animals that are given no antibiotics or growth hormones. Organic food is produced without using most conventional pesticides; fertilizers made with synthetic ingredients or sewage sludge; bioengineering; or ionizing radiation." Organic farmers apply techniques first used thousands of years ago, such as crop rotation and the use of composted animal manure and green cover crops to maintain long-term soil health and fertility. Organic production uses biological control to manage weeds, insects and diseases, and organic livestock production adheres to the humane treatment of animals. But are organic foods better for us? Learn more about what organic foods do and do not contain and how to apply this knowledge when purchasing groceries for you and your family.
Video by TheVisualMD
This browser does not support the video element.
Dr. David L. Katz, MD on all natural claims
Dr. David L. Katz, MD on "all natural" claims
Video by TheVisualMD
What's the Best Diet? Healthy Eating 101
Video by DocMikeEvans/YouTube
Healthy Eating with My Family
Video by My Doctor - Kaiser Permanente/YouTube
Eating Healthy on a Budget
Video by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)/YouTube
Minerals - What Are Minerals - What Do Minerals Do - What Are The Essential Minerals
Video by Whats Up Dude/YouTube
Basket of Nutrients
TheVisualMD / Gerhard G.
1:23
What are Vitamins and Minerals?
TheVisualMD
1:20
Salt & Other Minerals
TheVisualMD
2:14
Vitamins and Minerals in Aloe Vera - Health Benefits of Aloe Vera
Foods4Health/YouTube
1:36
Functional Foods
TheVisualMD
0:26
Nutritionist Chrissy Wellington, MS on whole foods
TheVisualMD
0:18
Nutritionist Chrissy Wellington, MS on fresh foods
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)/YouTube
2:39
Minerals - What Are Minerals - What Do Minerals Do - What Are The Essential Minerals
Whats Up Dude/YouTube
What Is the TLC Diet?
How Food Becomes You
Image by TheVisualMD
How Food Becomes You
You are what you eat, and the foods we eat quite literally become a part of us. What we ingest is broken down within our bodies into key nutrients that are responsible for proper growth and function. Paying close attention to the foods that we put into our body has lifelong benefits, from helping us grow from tiny babies into strong adults, to preventing or fighting chronic disease, or simply making us feel happy and active as we enjoy life's many pleasures.
Image by TheVisualMD
What Is the TLC Diet?
The TLC diet is a heart-healthy eating plan that helps make choosing, preparing, and cooking foods easier and healthier.
At the core of the TLC diet, it's important to:
Decrease saturated fat and cholesterol
Add plant stanols and sterols found in whole grains, nuts, legumes, and oils, like olive and avocado oil
Increase soluble fiber like in fruits, beans, and oats
Source: National Heart, Lung, and Blood Institute (NHLBI)
Additional Materials (12)
Mediterranean diet foods
Image by G.steph.rocket/Wikimedia
greek vegetables
Image by xxsbiene/Pixabay
Greek Vegetable Salad
Image by Pixabay/Pexels
Building blocks of the body
Can you see what this man is made of? His musculature and skeleton are images from real medical scans. Muscles like that are built from turkey and tofu. Cantaloupe, packed with vitamin C and beta carotene, formed the eyes. His bones are strengthened by yogurt and spinach. Eating is a daily opportunity to choose new building blocks for a stronger, more healthful body. You cannot choose your genes. You cannot choose the experiences that have built the body you have now. But you can choose a salmon filet, knowing that the omega-3 fatty acids will help you avoid coronary heart disease and macular degeneration. You can reject the heart-threatening trans fats in many convenience foods for a more healthful monounsaturated fat, like olive or canola oil. Knowing what you are made of, and what nutrients you need to maintain balance, will be essential to building a life of health and wellness.
Image by TheVisualMD
Hummus - mediteranean dish
Image by jcvelis/Pixabay
mediteranean diet
Image by goranprodan1/Pixabay
Healing Through Food: Can Diet and Lifestyle Heal Chronic Disease?
Video by NBC 6 South Florida/YouTube
TLC DIET Explained
Video by IdeaVideos/YouTube
Weight Loss 5×5® for Therapeutic Lifestyle Changes (TLC)
Video by Frederick Sutter, MD/YouTube
Therapeutic Lifestyle Changes for Prediabetes and Type 2 Diabetes
Video by Great Valley Publishing/YouTube
What exactly is the TLC diet?
Video by TechnoPedia Tupe/YouTube
TLC Diet presented by Debra Kirk RN
Video by Boulder Valley Care Network/YouTube
Mediterranean diet foods
G.steph.rocket/Wikimedia
greek vegetables
xxsbiene/Pixabay
Greek Vegetable Salad
Pixabay/Pexels
Building blocks of the body
TheVisualMD
Hummus - mediteranean dish
jcvelis/Pixabay
mediteranean diet
goranprodan1/Pixabay
3:05
Healing Through Food: Can Diet and Lifestyle Heal Chronic Disease?
NBC 6 South Florida/YouTube
6:11
TLC DIET Explained
IdeaVideos/YouTube
1:39
Weight Loss 5×5® for Therapeutic Lifestyle Changes (TLC)
Frederick Sutter, MD/YouTube
1:03:15
Therapeutic Lifestyle Changes for Prediabetes and Type 2 Diabetes
Great Valley Publishing/YouTube
2:13
What exactly is the TLC diet?
TechnoPedia Tupe/YouTube
1:07
TLC Diet presented by Debra Kirk RN
Boulder Valley Care Network/YouTube
TLC’s Dietary Recommendations
Human nutrition - Healthy Diet
Image by TheVisualMD
Human nutrition - Healthy Diet
Diet for Back Pain : Eating foods that are high in nutrients-like fruits and vegetables, whole grains, nuts, beans, and seeds-is excellent insurance against back pain. People with higher levels of nutrients in their blood tend to be healthier and less likely to have health disorders. Certain supplements may have a place in your health regimen, but they should always play a supporting role, not a leading role. Eating a nutritious diet has been shown to be much more helpful in maintaining health than eating a not-so-healthy diet and taking multiple supplements.
Image by TheVisualMD
TLC’s Dietary Recommendations
The TLC Diet pinpoints lowering daily intake of saturated fat because too much of this type of fat increases cholesterol in the blood, LDL cholesterol in particular. Limiting intake of foods rich in saturated fat also helps reduce intake of cholesterol from food. To help lower cholesterol levels more, the TLC Diet recommends adding soluble fiber and plant stanols and sterols to daily meals. Soluble fiber blocks cholesterol and fats from being absorbed through intestinal walls into the bloodstream. As with soluble fiber, plant stanols and sterols help block the absorption of cholesterol from the digestive tract, which helps to lower LDL cholesterol. Making these three important dietary changes daily are important for successfully following the TLC Diet to treat and lower LDL cholesterol.
Source: National Heart, Lung, and Blood Institute (NHLBI)
Additional Materials (4)
Healthy Diet
Contrary to what many people think, there is no specific "diabetes diet." A diet plan for someone with diabetes is simply a diet that is rich in nutrients and fiber and low in saturated and trans fats as well as refined carbohydrates. It's a diet that would be healthy for anyone at all, but may involve a calorie limitation. Healthy nutrition will help a person with diabetes to lower his or her blood glucose levels and lose weight if necessary-but remember that nutritious food isn't necessarily low fat (nuts, for instance, are high in calories), so serving sizes should be kept moderate. Eating at regular mealtimes helps to stabilize blood sugar.
Image by TheVisualMD
Shopping List for the Omnivore Diet
View the recommended food items for maintaining a healthy omnivore diet.
Image by TheVisualMD
Shopping List for the Vegetarian Diet
View the recommended food items for maintaining a healthy vegetarian diet.
Image by TheVisualMD
Eat Healthy
Eating a healthy diet can be an effective, and enjoyable, way to prevent cardiovascular and other disease. Good eating means focusing both on the foods you shouldn't eat and on the foods you should eat.
Image by TheVisualMD
Healthy Diet
TheVisualMD
Shopping List for the Omnivore Diet
TheVisualMD
Shopping List for the Vegetarian Diet
TheVisualMD
Eat Healthy
TheVisualMD
Heart-Healthy Living — Choose Heart-Healthy Foods
Healthy Eating
Image by StoryMD
Healthy Eating
Nutrition can absolutely impact fertility. In fact, your diet, and the other things that you choose to consume or not consume (think: cigarettes, alcohol, or drugs), is the single greatest factor that you have control over that can help support your odds of conception and maintain a healthy pregnancy.
Image by StoryMD
Heart-Healthy Living — Choose Heart-Healthy Foods
Heart-healthy eating involves choosing certain foods, such as fruits and vegetables, while limiting others, such as saturatedfats and added sugars.
Your doctor may recommend the heart-healthy Dietary Approaches to Stop Hypertension (DASH) eating plan because it has been proven to lower high blood pressure and “bad” LDL cholesterol in the blood.
Foods to eat
These foods are the foundation of a heart-healthy eating plan.
Vegetables such as leafy greens (spinach, collard greens, kale, cabbage), broccoli, and carrots
Fruits such as apples, bananas, oranges, pears, grapes, and prunes
Whole grains such as plain oatmeal, brown rice, and whole-grain bread or tortillas
Fat-free or low-fatdairy foods such as milk, cheese, or yogurt
Protein-rich foods:
Fish high in omega-3 fatty acids (salmon, tuna, and trout)
Lean meats such as 95% lean ground beef or pork tenderloin or skinless chicken or turkey
Eggs
Nuts, seeds, and soy products (tofu)
Legumes such as kidney beans, lentils, chickpeas, black-eyed peas, and lima beans
Oils and foods high in monounsaturated and polyunsaturated fats:
Canola, corn, olive, safflower, sesame, sunflower, and soybean oils (not coconut or palm oil)
Nuts such as walnuts, almonds, and pine nuts
Nut and seed butters
Salmon and trout
Seeds (sesame, sunflower, pumpkin, or flax)
Avocados
Tofu
Foods to limit
A heart-healthy eating plan limits sodium (salt), saturated fat, added sugars, and alcohol. Understanding nutrition labels can help you choose healthier foods.
Limit sodium
Adults and children over age 14 should eat less than 2,300 milligrams of sodium a day. Children younger than age 14 may need to eat even less sodium each day based on their sex and age. If you have high blood pressure, you may need to limit sodium even more. Talk to your healthcare provider about the amount of sodium that is right for you or your child.
Try these shopping and cooking tips to help you choose and prepare foods that are lower in sodium:
Read food labels and choose products that have less sodium for the same serving size.
Choose low-sodium, reduced-sodium, or no-salt-added products.
Choose fresh, frozen, or no-salt-added foods instead of pre-seasoned, sauce-marinated, brined, or processed meats, poultry, and vegetables.
Eat at homemore often so you can cook food from scratch, which will allow you to control the amount of sodium in your meals.
Flavor foods with herbs and spices instead of salt.
When cooking, limit your use of premade sauces, mixes, and instant products such as rice, noodles, and ready-made pasta.
Limit saturated fats
Saturated or “bad” fats come from animal sources such as butter, cheese, and fatty meats. They should make up less than 10% of your daily calories. Unsaturated fats are also known as “good” fats and are found in vegetable oils and nuts.
Read food labels and choose foods that are lower in saturated fats and higher in unsaturated fats.
Eat leaner, lower-fat, and skinless meats instead of fatty cuts of meat and chicken with skin.
Consume lower-fat dairy products instead of whole-milk.
Use certain vegetable oils (such as olive and canola oil)insteadof butter, lard, and coconut and palm oils.
Limit added sugars
You should limit the amount of calories you get each day from added sugars. This will help you choose nutrient-rich foods and stay within your daily calorie limit.
Some foods, such as fruit, contain natural sugars. Added sugars do not occur naturally in foods but instead are used to sweeten foods and drinks. They include brown sugar, corn syrup, dextrose, fructose, glucose, high-fructose corn syrup, raw sugar, and sucrose.
In the United States, sweetened drinks, snacks, and sweets are the major sources of added sugars.
Sweetened drinks include soft drinks or sodas, fruit drinks, sweetened coffee and tea, energy drinks, alcoholic drinks, and favored waters. Sweetened drinks account for about half of all added sugars consumed.
Snacks and sweets include grain-based desserts such as cakes, pies, cookies, brownies, doughnuts; dairy desserts such as ice cream, frozen desserts, and pudding; candies; sugars; jams; syrups; and sweet toppings.
Lower how much sugar you eat or drink.
Choose drinks without added sugarsuch as water, low-fat or fat-free milk, or 100% vegetable juice.
Choose unsweetened foods for snacks or dessert.
Eat sweetened drinks, snacks, and desserts less often and in smaller amounts.
Limit alcohol
Talk to your healthcare provider about how much alcohol you drink. They may recommend that you reduce the amount of alcohol you drink or that you stop drinking alcohol. Alcohol can:
Add calories to your daily diet and possibly cause you to gain weight
Raise your blood pressure and levels of triglyceride fats in your blood
Contribute to or worsen heart failure in some people, such as some people who have cardiomyopathy
Raise your risk of other diseases such as cancer
If you do not drink, you should not start. You should not drink if you are pregnant, are under the age of 21, taking certain medicines, or if you have certain medical conditions, including heart failure.
How much should you eat?
You should eat the right amount of calories for your body, which will vary based on your sex, age, and physical activity level. Remember that some healthy foods, including oils and dairy, can still have a lot of calories. Some fruits can have a lot of natural sugar, especially when they are dried.
You can visit the U.S. Department of Health and Human Services’ and U.S. Department of Agriculture’s 2020–2025 Dietary Guidelines for Americans has information about healthy eating and recommendations for healthy eating patterns.
Source: National Heart, Lung, and Blood Institute
Additional Materials (21)
Beat Stress with Healthier Foods
Did you know that choosing the right foods can combat the effects of stress? Tryptophan - This amino acid is a precursor to the neurotransmitter serotonin and the hormone melatonin, two calming biochemicals. What food is richest in tryptophan? Sea lion kidneys. (If your tastes aren't that exotic, you can find it in seaweed, soy, eggs and sesame seeds.)Omega-3s - These fatty acids help control stress-related hormones and are nutritionally beneficial to your cardiovascular system as well. Find them in cold-water oily fishes (salmon, herring, mackerel, anchovies, sardines) as well as seaweed, walnuts, and flaxseeds.Vitamin B6 - This vitamin helps the body build such neurotranmitters as serotonin, and may help boost immunity. Find it in chicken breast, yellowfin tuna, bell peppers, spinach, peanuts, beans, legumes, and whole grains.Vitamin B12 - B12 is key to serotonin and melatonin production. Foods high in vitamin B12 include shellfish, liver, meats, and any of the fishes high in omega 3s.Folic acid - Also known as vitamin B9 or folate, folic acid is an essential vitamin (the body can't produce it alone). It helps fight depression and fatigue. Eat liver, herbs, sunflower seeds, edamame, dark leafy greens, and beans to get adequate B9.Melatonin - This hormone regulates your sleep-wake cycle and has calming effects. Oats, dairy foods and rice contain small amounts, but to really affect your melatonin levels you should also eat foods high in tryptophan, which is melatonin's precursor.L-theanine - This amino acid derivative is shown to lower blood pressure and reduce stress. Find it in green teas and bay bolete mushrooms.
Image by TheVisualMD
Build a Healthy Eating Routine
Document by Office of Disease Prevention and Health Promotion
British Heart Foundation - Your weight and heart disease
Video by British Heart Foundation/YouTube
How to eat a heart-healthy diet
Video by Sunnybrook Hospital/YouTube
Heart Healthy Aging with Nutrition
Video by Alliance for Aging Research/YouTube
Cardiology: Diabetes and Heart Disease
Video by Lee Health/YouTube
Lettuce 101 - Nutrition and Health Benefits of Lettuce
Video by Judi in the Kitchen/YouTube
Fact or Fiction? Debunking Exercise & Nutrition Myths for Preventing Heart Disease & Risk Factors
Video by Mayo Clinic/YouTube
Risk Factors
Certain risk factors increase your chances of becoming obese. Some you can change, and some you can’t.Risk factors you can’t modify include:Genetics. Your genes can affect how much body fat you store and where you store it, as well as how efficiently your body converts food into energy and how efficiently you burn calorie during exercise. Studies of adopted children have shown that they tend to put on weight in a way that’s more similar to their biological parents than their adoptive parents. But genes are just part of the problem. Obesity rates have taken off in just the last few decades—far too short a period of time for the human gene pool to have altered significantly!
Age. As we age we tend to become less active. Muscle mass tends to decrease with age, and hormonal changes encourage the accumulation of fat. Lower muscle mass also leads to a decrease in metabolism. If you don’t decrease your caloric intake as you get older, you’ll probably put on weight.
Image by TheVisualMD
British Heart Foundation - Cholesterol and heart disease
Video by British Heart Foundation/YouTube
British Heart Foundation - High blood pressure and heart disease
Video by British Heart Foundation/YouTube
Heart healthy foods to consume — and what to avoid
Video by Business Insider/YouTube
Top 5 Heart Health Tips
Video by Sunnybrook Hospital/YouTube
Nutrition to Improve Your Cholesterol
Video by Lee Health/YouTube
Keep the Beat Recipes: Deliciously Healthy Dinners
What’s good for your heart is great for your taste buds! The recipes in this
cookbook show that you don’t have to lose flavor to eat nutritious foods.
Keep the Beat™ Recipes: Deliciously Healthy Dinners contains 75 heart healthy
recipes. More than two-thirds of these recipes were created for the National
Heart, Lung, and Blood Institute (NHLBI) by a Culinary Institute of Americatrained chef and a James Beard Foundation award-winning registered dietitian.
The remaining recipes come from popular NHLBI cookbooks—Keep the Beat™
Heart Healthy Recipes from the NHLBI, Heart Healthy Home Cooking African
American Style, and Delicious Heart Healthy Latino Recipes.
Document by healthyeating.nhlbi.nih.gov
Tips to Eat Less Salt and Sodium
From the NHLBI, find tips for reducing dietary sodium and salt.
Document by www.nhlbi.nih.gov
Get the Facts: Sodium and the Dietary Guidelines
Reduce sodium in your diet.
Document by www.cdc.gov
Delicious Heart-Healthy Latino Recipes
Document by National Heart, Lung, and Blood Institute
Cut Down on Sodium
Document by www.dietaryguidelines.gov
Heart Healthy Home Cooking, African American Style, With Every Heartbeat Is Life
This recipe book brings together
many African American favorite recipes, prepared in a heart
healthy way, lower in saturated fat, cholesterol, and sodium!
Document by www.nhlbi.nih.gov
Heart-Healthy Eating Plan
A heart-healthy eating plan emphasizes vegetables, fruits, and whole grains, includes fat-free or low-fat dairy products. In this fact sheet, you will learn how much you should eat from each food group.
Document by NHLBI
Beat Stress with Healthier Foods
TheVisualMD
Build a Healthy Eating Routine
Office of Disease Prevention and Health Promotion
6:51
British Heart Foundation - Your weight and heart disease
British Heart Foundation/YouTube
10:59
How to eat a heart-healthy diet
Sunnybrook Hospital/YouTube
4:37
Heart Healthy Aging with Nutrition
Alliance for Aging Research/YouTube
1:57
Cardiology: Diabetes and Heart Disease
Lee Health/YouTube
4:06
Lettuce 101 - Nutrition and Health Benefits of Lettuce
Judi in the Kitchen/YouTube
5:11
Fact or Fiction? Debunking Exercise & Nutrition Myths for Preventing Heart Disease & Risk Factors
Mayo Clinic/YouTube
Risk Factors
TheVisualMD
6:23
British Heart Foundation - Cholesterol and heart disease
British Heart Foundation/YouTube
7:37
British Heart Foundation - High blood pressure and heart disease
British Heart Foundation/YouTube
1:22
Heart healthy foods to consume — and what to avoid
Business Insider/YouTube
3:19
Top 5 Heart Health Tips
Sunnybrook Hospital/YouTube
1:52
Nutrition to Improve Your Cholesterol
Lee Health/YouTube
Keep the Beat Recipes: Deliciously Healthy Dinners
healthyeating.nhlbi.nih.gov
Tips to Eat Less Salt and Sodium
www.nhlbi.nih.gov
Get the Facts: Sodium and the Dietary Guidelines
www.cdc.gov
Delicious Heart-Healthy Latino Recipes
National Heart, Lung, and Blood Institute
Cut Down on Sodium
www.dietaryguidelines.gov
Heart Healthy Home Cooking, African American Style, With Every Heartbeat Is Life
www.nhlbi.nih.gov
Heart-Healthy Eating Plan
NHLBI
Eating Well with TLC
Healthy Diet
Image by Devon Breen
Healthy Diet
Image by Devon Breen
Eating Well with TLC
While the TLC Diet means eating well for good heart health, it also means learning how to eat well – in other words, how to best prepare or cook foods so that they are heart-healthy.
Eating heart-healthy meals doesn’t mean giving up on taste. The TLC diet recommends limiting serving sizes or replacing foods high in saturated fat and cholesterol with healthier options. Fruits, vegetables, legumes (beans and lentils), nuts, whole grains, low- or non-fat dairy products, fish, poultry without the skin, and in moderate amounts, lean meats are good options.
It’s also important to limit sodium intake to 2,300 milligrams each day. Salt-free spices and herbs can make your heart-healthy meals tasty.
Source: National Heart, Lung, and Blood Institute (NHLBI)
Additional Materials (3)
Healthy Nutrition
It's estimated that diet causes about one-third of all cancer cases, almost as many as tobacco. The importance of diet in preventing cancer was shown in a study that tracked patients with colorectal cancer. After their cancer had been surgically removed, these patients were followed for 5 years. Those who ate a traditional Western diet had a three times greater likelihood of having their cancer recur than those who ate a healthy diet, rich in fruits and vegetables and containing only small amounts of red meat. The Western diet stimulated the growth of the cancer cells that remained in their bodies.
Image by TheVisualMD
The Benefits of Good Habits
The brain`s prefrontal cortex, right behind the forehead, manages executive control-the task of choosing a thought or action to meet a goal. The closely linked orbitofrontal cortex and amygdala help regulate decision-making based on the memory of feelings that resulted from past decisions. Our memory forges shortcuts that help us take action without thinking through the consequences.
Image by TheVisualMD
Healthy Superfood Selection
Make nutrition a priority by eating healthy nutrient-rich foods to help support your immune system.
Image by Marilyn Barbone
Healthy Nutrition
TheVisualMD
The Benefits of Good Habits
TheVisualMD
Healthy Superfood Selection
Marilyn Barbone
How Can You Lower Blood Triglyceride Levels?
Mediterranean diet foods
Image by G.steph.rocket/Wikimedia
Mediterranean diet foods
Image by G.steph.rocket/Wikimedia
How Can You Lower Blood Triglyceride Levels?
Lifestyle changes
If you are diagnosed with high blood triglycerides, your healthcare provider may recommend that you make heart-healthy lifestyle changes.
Choose heart-healthy foods.
Get regular physical activity. Before starting any exercise program, ask your provider what level of physical activity is right for you.
Aim for a healthy weight.
Manage stress.
Quit smoking. For free help and support to quit smoking, you may call the National Cancer Institute’s Smoking Quitline at 1-877-44U-QUIT (1-877-448-7848).
Get enough good quality sleep.
Limit alcohol. If your blood triglyceride levels are considered very high, your provider may recommend stopping alcohol use. Visit the National Institute on Alcohol Abuse and Alcoholism for resources on support and treatment to stop drinking.
Medicines
Your healthcare provider may prescribe a few different types of medicines to control or lower your triglyceride levels.
Fibrateslower the number of triglycerides in the blood. These medicines may also be used to lower cholesterol.
Concentrated omega-3 fatty acidsare available by prescriptionfor treating triglyceride levels of 150 mg/dL or above. These medicines are made differently than omega-3 dietary supplements, which are not FDA-approved to treat people with high triglyceride levels.
Statins are the most common medicine used to treat high blood cholesterol but can also be used to lower the levels of triglycerides in the blood. Learn more about how you can stay safe while taking statins.
Ezetimibe, another cholesterol-lowering medicine, can also be used to remove triglycerides from the blood when paired with a healthy diet.
More than one medicinemay be necessary to treat very high levels of triglycerides.
Source: National Heart, Lung, and Blood Institute (NHLBI)
Additional Materials (3)
Examples of the Mediterranean Diet
Examples of the Mediterranean Diet
Image by DanaTentis
Lowering Triglycerides - Mayo Clinic
Video by Mayo Clinic/YouTube
High Triglycerides: The Latest Recommendations
Video by Medscape/YouTube
Examples of the Mediterranean Diet
DanaTentis
2:46
Lowering Triglycerides - Mayo Clinic
Mayo Clinic/YouTube
5:25
High Triglycerides: The Latest Recommendations
Medscape/YouTube
TLC Program - Physical Activity
Benefits of Exercise
Image by TheVisualMD
Benefits of Exercise
Whether you are starting a new fitness program, or fine-tuning your current workouts, thoughtful planning will help you get more benefits from exercise. You need to make sure that you are getting aerobic exercise, which uses large amounts of oxygen as you work—jogging, brisk walking, swimming and bicycling are aerobic exercise. You also need anaerobic exercise, muscle-building work which is performed in shorter, intense bursts of activity and draws on your body's glucose and fats for energy—weight-lifting and sprinting are good ones. Adding stretching activity to your workouts, such as yoga or Pilates, increases your range of motion and can work additional muscle groups that might otherwise be neglected. It is important to choose sports and activities that you really like, so you will have enough variety and engagement to stay interested and enthusiastic about exercising.
Image by TheVisualMD
TLC Program - Physical Activity
Increasing physically activity is another key part of the TLC Program — it’s a step that has many benefits. Lack of physical activity is a major risk factor for heart disease. Regular physical activity and reducing sedentary behavior can help with managing weight and, in that way, help lower LDL cholesterol. It also can help raise HDL cholesterol and lower triglycerides, improve the fitness of the heart and lungs, and lower high blood pressure. Additionally, it can reduce risks for developing diabetes or, if already present, lessen the need for insulin.
Source: National Heart, Lung, and Blood Institute (NHLBI)
Additional Materials (3)
Physical fitness
Keep It Moving : Anerobic means "without oxygen." Anerobic exercise triggers anerobic metabolism, defined as the creation of energy through the combustion of carbohydrates in the absence of oxygen. Anerobic metabolism occurs when the lungs can't put enough oxygen into the bloodstream to keep up with the demands from your muscles for energy. Instead, your muscles use glycogen as fuel. Examples: sprinting, jumping, lifting weights.
Image by TheVisualMD
Yoga Stretch
An adult male stands in Extended Side Angle pose on a yoga mat. His brain, skeletal muscles and some bones are visible. Yoga is often recommended as an activity that safely combines fluid stretching and movement to improve flexibility, strength and balance.
Image by TheVisualMD
Aerobic and Anaerobic Exercise - Patients with Alzheimer's disease, major depression and other neurodegenerative diseases have lower levels of this protein. Your workout not only improves your strength, endurance and flexibility, it can help keep your brain at the top of its game.
This fit cyclist, as visualized by TheVisualMD.com, is an impressive example of how exercise can build lean muscles and a sturdy skeleton. But did you know that exercise can also protect and build up his brain? During exercise, the brain secretes more of a protein called BDNF—brain derived neurotrophic factor. BDNF protects existing neurons and axons, and encourages the growth of new nerve cells. The factor plays a role in memory and learning as well as metabolism. Another indicator of BDNF's power: Patients with Alzheimer's disease, major depression and other neurodegenerative diseases have lower levels of this protein. Your workout not only improves your strength, endurance and flexibility, it can help keep your brain at the top of its game.
Image by TheVisualMD
Physical fitness
TheVisualMD
Yoga Stretch
TheVisualMD
Aerobic and Anaerobic Exercise - Patients with Alzheimer's disease, major depression and other neurodegenerative diseases have lower levels of this protein. Your workout not only improves your strength, endurance and flexibility, it can help keep your brain at the top of its game.
TheVisualMD
Physical Activity and Your Heart
Build a Better Cardiovascular System
Image by TheVisualMD
Build a Better Cardiovascular System
Aerobic exercise turns your heart, lungs and blood vessels into a strong, efficient system. As you build endurance, your body adjusts, growing networks of new blood vessels to accommodate larger amounts of incoming oxygen. Your heart strengthens. Your blood pressure lowers. You're in the flow.
Image by TheVisualMD
Physical Activity and Your Heart
Physical activity is any body movement that works your muscles and requires more energy than resting. Walking, running, dancing, swimming, yoga, and gardening are a few examples of physical activity.
According to the Department of Health and Human Services' 2018 Physical Activity Guidelines for Americans physical activity generally refers to movement that enhances health. Physical activity is recommended for everyone from 3 years of age and older.
Types of physical activities include aerobic, muscle-strengthening, bone-strengthening, balance, and flexibility activities. Exercise is physical activity that is planned and structured, such as lifting weights, taking an aerobics class, or playing on a sports team.
Physical activity is good for many parts of your body. This topic focuses on the benefits for your heart and lungs and provides tips for getting started and staying active. Physical activity is one part of a heart-healthy lifestyle. A heart-healthy lifestyle also involves following a heart-healthy eating, aiming for a healthy weight, managing stress, and quitting smoking.
Being physically active is one of the best ways to keep your heart and lungs healthy. Many Americans are not active enough. The good news, though, is that even modest amounts of physical activity are good for your health. The more active you are, the more you will benefit.
Source: NIH: National Heart, Lung, and Blood Institute
Additional Materials (34)
This browser does not support the video element.
Exercise & Your Health
The energy demands of exercise require support from every major system in the body. Your heart, lungs, bones and brain are engaged. The positive effects of regular exercise strengthen your endocrine and immune systems, reduce stress, combat arthritis and obesity, and help you sleep better. It is also associated with lower risk of cancer, diabetes, cardiovascular disease and other ailments. No medication or other treatment can come close to the whole-body benefits of regular exercise, especially when combined with other healthful lifestyle choices.
Video by TheVisualMD
Your Guide to Physical Activity and Your Heart
This booklet will help you to understand the impact of physical
activity on your heart, as well as the power of regular activity to
help keep you healthy overall. It will also offer plenty of ideas on
starting a physical activity program that will be both healthful and
enjoyable. Just as important, you’ll get tips for keeping up with the
activity or activities you choose, since staying active over time is
important to long-term health. So use this booklet often for information,
ideas, and to keep you motivated. When to start getting fit?
There’s no time like today.
Document by National Heart, Lung, and Blood Institute
How Exercise Improves Heart Health – Healthfirst Healthy Living
Video by Healthfirst/YouTube
How playing sports benefits your body ... and your brain - Leah Lagos and Jaspal Ricky Singh
Video by TED-Ed/YouTube
What happens inside your body when you exercise?
Video by British Heart Foundation/YouTube
Are You Sitting Too Much?
Video by AsapSCIENCE/YouTube
Cardiac Rehab
Video by ToriVogt/YouTube
This browser does not support the video element.
The Ryan Bendixon Story
A case study of Ryan Bendixon dealing with hypertension. Ryan is an active person, a soldier who's a model of physical fitness. He is diet conscious, he's working out, he's healthy. But an army physical revealed that although Ryan is young and healthy, he has a genetic hypertension. His condition might lead to stroke and could kill him. Hypertension results to a thickened vessel wall, causing pressure in the vessel, damaging its inner layer. The damage could extend to any tissue in the body. Blood pressure pill is a solution to genetic hypertension. Dr. John Castaldo, a neurologist, explains that blood pressure pill can treat hypertension very well with very minimal side effects. CT scanning ( a diagnostic test using x-ray that produces highly detailed slices of the body ) is done revealing 3 dimensional images of the heart, lungs, and arteries. The scans of Ryan's heart show that Ryan's hypertension is under control.
Video by TheVisualMD
Top 5 Heart Health Tips
Video by Sunnybrook Hospital/YouTube
90:10 The Single Most Important Thing You Can Do For Your Stress
Video by DocMikeEvans/YouTube
This browser does not support the video element.
I Need a Miracle
This is the story of John Barlow's physical transformation through Canyon Ranch's fitness program. At the start, a series of medical exams and scans is conducted to reveal many health problems and conditions that John is facing. A cardiologist explains that arterial plaque blocks the blood flow in his John's heart, giving him the potential of having a heart disease. Dr. Mark Liponis of the Canyon Ranch Health Resort serves as the principle architect in charge of guiding John back to a state of healthy well-being. Further exams - taking blood pressure, blood tests, examining the ear, eye, and oral cavity, EKG, and stress test reveal blockages in John's coronary arteries (network of arteries that supply blood to the heart). As the video shows the internal organs of his body, John is telling the problems about his health. Not only that some of the arteries in his heart are narrowed, but John's insulin resistance is low, he is overweight, he has constant back pain, and he is allergic to a lot of food. Because of these findings, big changes should be done in 4 months. John faces the challenges like working out, changing his diet, having acupuncture treatment and others. After 2 months, John is put to the next level of the fitness program. Can be seen that John is continuously trying to improve his health until the fourth month. In his final stress test, the result tells that a lot of changes happen. As the video shows scans and slices of John's body, John is telling that the restriction in his heart's blood flow is gone, his cholesterol went down, his insulin resistance improved, and his body fat dropped. Dr. Mark Liponis is explaining that 4 months ago, John is 56 yrs. old but has a body of 80 yrs old. After the fitness program, at the age of 56, John has a body of a 52 yr old. Through an intensive four month period of physical activity, healthy eating, and wellness training, John is able to completely transform his body.
Video by TheVisualMD
Be Active — Keep Your Heart Healthy!
Video by NHLBI/YouTube
Who Encourages You to Move More to Keep Your Heart Healthy? #MovingStory with Dr. Kimberly Leonard
Video by NHLBI/YouTube
British Heart Foundation - 10 minute living room workout
Video by British Heart Foundation/YouTube
British Heart Foundation - Your guide to an exercise ECG (stress test), heart disease test
Video by British Heart Foundation/YouTube
On The Move After A Heart Attack
Video by LivingHealthyChicago/YouTube
British Heart Foundation - Strength and flexibility exercises
Video by British Heart Foundation/YouTube
Does Sex Count as Exercise for Your Heart?
Video by Johns Hopkins Medicine/YouTube
What should your heart rate be when you exercise (if you are a heart patient)
Video by Cleveland Clinic/YouTube
Best exercises for your heart
Video by CNN/YouTube
How Physical Activity Boosts Heart Health
Video by Johns Hopkins Medicine/YouTube
Exercise Series-Is There An Ideal Exercise/Activity for Your Heart?
Video by Mayo Clinic/YouTube
Physical Activity and Heart Health
Video by American Heart Association/YouTube
The Importance of Intensity in Physical Activity
Video by DocMikeEvans/YouTube
How the Heart Changes with Exercise
Video by Institute of Human Anatomy/YouTube
Heart Foundation | Heart failure and physical activity
Video by Heart Foundation/YouTube
Heart Health: Physical Activity
Video by Baylor College of Medicine/YouTube
Physical Activity Guidelines
Video by American Heart Association/YouTube
How to Feel Your Heart Beat
Video by SciShow Kids/YouTube
What is my target heart rate?
Video by British Heart Foundation/YouTube
Exercise zones Fox and Haskell
Exercise zones, Fox and Haskell formula between 20 and 70-year-old
Image by Morgoth666/Wikimedia
Athlete training to increase his heart lung capacity
Athlete training to increase his heart lung capacity
Image by TheVisualMD
Build a Better Cardiovascular System
Aerobic exercise turns your heart, lungs and blood vessels into a strong, efficient system. As you build endurance, your body adjusts, growing networks of new blood vessels to accommodate larger amounts of incoming oxygen. Your heart strengthens. Your blood pressure lowers. You're in the flow.
Image by TheVisualMD
American Heart Month 2020
Image by National Institutes of Health (NIH)
2:02
Exercise & Your Health
TheVisualMD
Your Guide to Physical Activity and Your Heart
National Heart, Lung, and Blood Institute
1:55
How Exercise Improves Heart Health – Healthfirst Healthy Living
Healthfirst/YouTube
3:47
How playing sports benefits your body ... and your brain - Leah Lagos and Jaspal Ricky Singh
TED-Ed/YouTube
2:33
What happens inside your body when you exercise?
British Heart Foundation/YouTube
3:02
Are You Sitting Too Much?
AsapSCIENCE/YouTube
3:25
Cardiac Rehab
ToriVogt/YouTube
2:56
The Ryan Bendixon Story
TheVisualMD
3:19
Top 5 Heart Health Tips
Sunnybrook Hospital/YouTube
11:01
90:10 The Single Most Important Thing You Can Do For Your Stress
DocMikeEvans/YouTube
0:00
I Need a Miracle
TheVisualMD
0:53
Be Active — Keep Your Heart Healthy!
NHLBI/YouTube
0:45
Who Encourages You to Move More to Keep Your Heart Healthy? #MovingStory with Dr. Kimberly Leonard
NHLBI/YouTube
11:06
British Heart Foundation - 10 minute living room workout
British Heart Foundation/YouTube
3:38
British Heart Foundation - Your guide to an exercise ECG (stress test), heart disease test
British Heart Foundation/YouTube
4:06
On The Move After A Heart Attack
LivingHealthyChicago/YouTube
9:29
British Heart Foundation - Strength and flexibility exercises
British Heart Foundation/YouTube
0:34
Does Sex Count as Exercise for Your Heart?
Johns Hopkins Medicine/YouTube
3:43
What should your heart rate be when you exercise (if you are a heart patient)
Cleveland Clinic/YouTube
1:01
Best exercises for your heart
CNN/YouTube
1:11
How Physical Activity Boosts Heart Health
Johns Hopkins Medicine/YouTube
12:02
Exercise Series-Is There An Ideal Exercise/Activity for Your Heart?
Mayo Clinic/YouTube
0:37
Physical Activity and Heart Health
American Heart Association/YouTube
3:28
The Importance of Intensity in Physical Activity
DocMikeEvans/YouTube
18:45
How the Heart Changes with Exercise
Institute of Human Anatomy/YouTube
1:27
Heart Foundation | Heart failure and physical activity
Heart Foundation/YouTube
0:28
Heart Health: Physical Activity
Baylor College of Medicine/YouTube
2:07
Physical Activity Guidelines
American Heart Association/YouTube
3:36
How to Feel Your Heart Beat
SciShow Kids/YouTube
1:00
What is my target heart rate?
British Heart Foundation/YouTube
Exercise zones Fox and Haskell
Morgoth666/Wikimedia
Athlete training to increase his heart lung capacity
TheVisualMD
Build a Better Cardiovascular System
TheVisualMD
American Heart Month 2020
National Institutes of Health (NIH)
Types of Physical Activity
Man Playing Tennis with Background
Image by TheVisualMD
Man Playing Tennis with Background
Regular physical activity helps to maintain fitness levels, which directly reduce the risk of disease and death. Even individuals with preexisting heart conditions are frequently prescribed mild exercise regimens by their healthcare professional in order to keep their health from deteriorating further. If you are overweight or have a medical condition, speak to your healthcare professional about how best to begin an exercise program. If you have not been physically active, it is a good idea to start slowly with moderate physical activity like walking, and gradually build up to the American Heart Association and the USDA recommended 30 minutes of physical activity a day. A half hour of more vigorous activities 3 to 5 times a week - such as jogging, swimming, or team sports - can have additional health benefits in strengthening and building muscles and bone mass. Physical activity can also help relieve day-to-day stress and tension.
Image by TheVisualMD
Types of Physical Activity
The three main types of physical activity are aerobic, muscle strengthening, and bone strengthening. Balance and flexibility activities are also beneficial. Aerobic activity is the type that benefits your heart and lungs the most. By understanding the different types of physical activity, benefits, and recommendations, you can create a plan to add physical activity into your healthy lifestyle.
Aerobic activity
Aerobic activity moves your large muscles, such as those in your arms and legs. Aerobic activity is also called endurance activity.
Aerobic activity makes your heart beat faster than usual. You also breathe harder during this type of activity. Over time, regular aerobic activity makes your heart and lungs stronger and able to work better.
Intensity levels of aerobic activity
You can do aerobic activity with different levels of intensity, including:
Light-intensity activities are common daily activities that don’t require much effort.
Moderate-intensity activities make your heart, lungs, and muscles work harder than light-intensity activities do. On a scale of 0 to 10, moderate-intensity activity is a 5 or 6 and produces noticeable increases in breathing and heart rate. A person doing moderate-intensity activity can talk but not sing.
Vigorous-intensityactivities make your heart, lungs, and muscles work hard. On a scale of 0 to 10, vigorous-intensity activity is a 7 or 8. A person doing vigorous-intensity activity can’t say more than a few words without stopping for a breath.
Moderate- and vigorous-intensity aerobic activities are better for your heart than light-intensity activities. However, even light-intensity activities are better than no activity at all.
The level of intensity depends on how hard you have to work to do the activity. To do the same activity, people who are less fit usually have to work harder than people who are more fit. So, for example, what is light-intensity activity for one person may be moderate-intensity for another.
Examples of aerobic activity
Depending on your fitness level, aerobic activity can be light, moderate, or vigorous in intensity:
Pushing a grocery cart around a store
Gardening, such as digging or hoeing that causes your heart rate to go up
Walking, hiking, jogging, running
Water aerobics or swimming laps
Bicycling, skateboarding, rollerblading, and jumping rope
Ballroom dancing and aerobic dancing
Tennis, soccer, hockey, and basketball
Muscle-strengthening activity
Muscle-strengthening activities improve the strength, power, and endurance of your muscles. Doing pushups and situps, lifting weights, climbing stairs, and digging in the garden are examples of muscle-strengthening activities.
Bone-strengthening activity
With bone-strengthening activities, your feet, legs, or arms support your body's weight, and your muscles push against your bones. This helps make your bones strong. Running, walking, jumping rope, and lifting weights are examples of bone-strengthening activities.
Muscle-strengthening and bone-strengthening activities also can be aerobic, depending on whether they make your heart and lungs work harder than usual. For example, running is both an aerobic activity and a bone-strengthening activity.
Balance activities
These kinds of activities can improve your ability to resist forces that can make you fall, either while stationary or moving. Walking backward, standing on one leg, walking heel-to-toe, practicing standing from a sitting position, or using a wobble board are examples of balance activities. Strengthening muscles of the back, abdomen, and legs also improves balance.
Flexibility activities
Stretching helps improve your flexibility and your ability to fully move your joints. Touching your toes, doing side stretches, and doing yoga exercises are examples of stretching.
Source: National Heart, Lung, and Blood Institute (NHLBI)
Additional Materials (7)
Cardio vs. strength training: What you need to know
Video by MD Anderson Cancer Center/YouTube
What type of exercise is best for my health?
Video by Science Animated/YouTube
How to Stay Safe While Doing 4 Types of Exercise
Video by National Institute on Aging/YouTube
What is Physical Activity? | Reduce your Cancer Risk | Cancer Research UK
Video by Cancer Research UK/YouTube
Physical activity
Video by Bracknell Forest Council/YouTube
Exercise-induced cardiac growth - Cardiac remodeling from Aerobic and Resistance exercise
FIGURE 2. Exercise-induced cardiac growth. Aerobic and resistance exercise elicit different forms of physiological cardiac remodeling. Hypertrophic responses are primarily eccentric in nature for aerobic exercise and concentric in nature for resistance exercise. LA, left atrium; LV, left ventricle; LVWT, left ventricular wall thickness; RA, right atrium; RV, right ventricle.
Image by Kyle Fulghum, Bradford G. Hill/Wikimedia
High Density Lipoprotein: Aerobic exercise
There are many factors that can potentially influence cholesterol levels. Exercise is an important one. Studies have shown that endurance athletes have higher HDL levels, and aerobic athletes in general, particularly lean ones, have lower LDL levels.
Image by TheVisualMD
1:06
Cardio vs. strength training: What you need to know
MD Anderson Cancer Center/YouTube
2:10
What type of exercise is best for my health?
Science Animated/YouTube
1:33
How to Stay Safe While Doing 4 Types of Exercise
National Institute on Aging/YouTube
1:05
What is Physical Activity? | Reduce your Cancer Risk | Cancer Research UK
Cancer Research UK/YouTube
0:54
Physical activity
Bracknell Forest Council/YouTube
Exercise-induced cardiac growth - Cardiac remodeling from Aerobic and Resistance exercise
Kyle Fulghum, Bradford G. Hill/Wikimedia
High Density Lipoprotein: Aerobic exercise
TheVisualMD
Benefits of Physical Activity
Benefits of Exercise
Image by TheVisualMD
Benefits of Exercise
Physical activity is critical for the health of your body. The risks posed to your health by a sedentary lifestyle are similar to those posed by hypertension, high blood triglyceride and cholesterol levels, and obesity.
Photo of woman sleeping: Copyright 2008, Hobvias Sudoneighm
Photo of people jumping: Copyright 2008, Evan Osherow
Image by TheVisualMD
Benefits of Physical Activity
Physical activity has many health benefits. These benefits apply to people of all ages, races and ethnicities, and sexes.
For example, physical activity helps you maintain a healthy weight and makes it easier to do daily tasks, such as climbing stairs and shopping.
Physically active adults are at lower risk for depression and declines in cognitive function as they get older. (Cognitive function includes thinking, learning, and judgment skills.) Physically active children and teens may have fewer symptoms of depression than their peers.
Physical activity also lowers your risk for many diseases, such as coronary heart disease, diabetes, and cancer.
Physical activity strengthens your heart and improves lung function
When done regularly, moderate- and vigorous-intensity physical activity strengthens your heart muscle. This improves your heart's ability to pump blood to your lungs and throughout your body. As a result, more blood flows to your muscles, and oxygen levels in your blood rise.
Capillaries, your body's tiny blood vessels, also widen. This allows them to deliver more oxygen to your body and carry away waste products.
When done regularly, moderate- and vigorous-intensity aerobic activity can lower your risk for coronary heart disease. This is a condition in which a waxy substance called plaque builds up inside your coronary arteries. These arteries supply your heart muscle with oxygen-rich blood.
Plaque narrows the arteries and reduces blood flow to your heart muscle. Eventually, an area of plaque can rupture (break open). This causes a blood clot to form on the surface of the plaque.
If the clot becomes large enough, it can mostly or completely block blood flow through a coronary artery. Blocked blood flow to the heart muscle causes a heart attack.
Certain traits, conditions, or habits may raise your risk for coronary heart disease. Physical activity can help control some of these risk factors by:
Lowering blood pressure and triglycerides (a type of fat in the blood)
Raising HDL (high density lipoproteins) (“good”) cholesterol levels
Reducing risk of overweight and obesity, when combined with a reduced-calorie diet
Maintaining a healthy weight over time once you have lost weight
Helping your body manage blood sugar and insulin levels, which lowers your risk for type 2 diabetes
Reducing levels of C-reactive protein (CRP), which is a sign of inflammation and an increased risk of heart disease
Possibly helping you quit smoking, which is a major risk factor for heart disease
Inactive people are more likely to develop heart disease than people who are physically active. Studies suggest that inactivity is a major risk factor for heart disease, just like high blood pressure, high blood cholesterol, and smoking.
Physical activity reduces heart attack risk
For people who have coronary heart disease, regular aerobic activity helps the heart work better. It also may reduce the risk of a second heart attack in people who already have had heart attacks.
Vigorous aerobic activity may not be safe for people who have heart disease. Ask your doctor what types of activity are safe for you. They can provide more information about recommended physical activities and steps to begin adding physical activity into your routine.
Physical activity can benefit your mental health and quality of life
Physically active adults are at lower risk for declines in cognitive function as they get older. Physically active children, teens, and older adults show improved cognition. Children show improved cognition after one session of physical activity.
Physically active children, teens, and adults are at lower risk for depression than their peers. Physical activity can also decrease feelings of anxiety, and regular activity can reduce long-term feelings and signs of anxiety.
It also makes it easier to do daily tasks, such as climbing stairs and shopping. It can also lead to better sleep and overall quality of life.
Source: National Heart, Lung, and Blood Institute (NHLBI)
Additional Materials (14)
What happens inside your body when you exercise?
Video by British Heart Foundation/YouTube
Aerobic Exercise & Capillary Growth
Aerobic Exercise & Capillary Growth
Image by TheVisualMD
How Exercise Improves Heart Health – Healthfirst Healthy Living
Video by Healthfirst/YouTube
You Need Aerobic Exercise
Running, swimming, rowing and brisk walking are aerobic exercises, the oxygen-powered activities that strengthen our cardiovascular system, increase our endurance, and burn fat. During aerobic exercise, we use oxygen to efficiently transform nutrients into large amounts of fuel.
Image by TheVisualMD
This browser does not support the video element.
Exercise & Your Health
The energy demands of exercise require support from every major system in the body. Your heart, lungs, bones and brain are engaged. The positive effects of regular exercise strengthen your endocrine and immune systems, reduce stress, combat arthritis and obesity, and help you sleep better. It is also associated with lower risk of cancer, diabetes, cardiovascular disease and other ailments. No medication or other treatment can come close to the whole-body benefits of regular exercise, especially when combined with other healthful lifestyle choices.
Video by TheVisualMD
This browser does not support the video element.
Exercise & Your Brain
Regular aerobic exercise is a workout for your brain. The neurons in your brain benefit from the release of a special factor during exercise called BDNF—brain-derived neurotrophic factor. It has been called “Miracle Gro” for the brain because of its ability to help maintain and strengthen brain neurons, enabling them to make new connections and pathways. Exercise is associated with lower incidence of Alzheimer's disease and other dementia disorders as well as better memory retention and decision-making.
Video by TheVisualMD
Health benefits of walking every day | Spiritual Lifestyle Tips | Healthy Tips | Habits
Video by Speaking Tree/YouTube
Exercise & Chronic Diseases
Video by AllHealthGo/YouTube
Why Walking Fast Is Good For Your Health | TIME
Video by TIME/YouTube
Stay Independent with Regular Exercise!
Video by National Institute on Aging/YouTube
Exercise benefits for cancer patients don't depend on cancer type
Video by Research Square/YouTube
Benefits of Physical Activity for Youth
Video by Centers for Disease Control and Prevention (CDC)/YouTube
Top 10 Benefits of Exercise
Video by Doctor Mike Hansen/YouTube
Exploring the importance of physical activity for brain health in children and youth
Video by IHDCYH Talks | Entretiens de l'IDSEA/YouTube
2:33
What happens inside your body when you exercise?
British Heart Foundation/YouTube
Aerobic Exercise & Capillary Growth
TheVisualMD
1:55
How Exercise Improves Heart Health – Healthfirst Healthy Living
Healthfirst/YouTube
You Need Aerobic Exercise
TheVisualMD
2:02
Exercise & Your Health
TheVisualMD
1:35
Exercise & Your Brain
TheVisualMD
3:59
Health benefits of walking every day | Spiritual Lifestyle Tips | Healthy Tips | Habits
Speaking Tree/YouTube
2:15
Exercise & Chronic Diseases
AllHealthGo/YouTube
1:12
Why Walking Fast Is Good For Your Health | TIME
TIME/YouTube
4:24
Stay Independent with Regular Exercise!
National Institute on Aging/YouTube
2:56
Exercise benefits for cancer patients don't depend on cancer type
Research Square/YouTube
1:15
Benefits of Physical Activity for Youth
Centers for Disease Control and Prevention (CDC)/YouTube
8:12
Top 10 Benefits of Exercise
Doctor Mike Hansen/YouTube
5:21
Exploring the importance of physical activity for brain health in children and youth
IHDCYH Talks | Entretiens de l'IDSEA/YouTube
Risks of Physical Activity
Male Thorax with Heart Pacemaker
Image by TheVisualMD
Male Thorax with Heart Pacemaker
Patients with heart failure resulting from a heart attack usually have an enlarged heart. This occurs as the result of what is known as remodeling or changes to the heart due to muscle damage and scar tissue. Another complication of a heart attack is arrhythmia - in which the electrical activity of the heart goes \"haywire.\" Scar tissue formed as a result of damage cannot conduct the electrical signals of the heart from one cell to another, and as a result a patient may experience irregular heartbeats or skipped beats. A specific type of arrhythmia - ventricular arrhythmia - can cause sudden cardiac death and is thought to be responsible for half of all deaths due to heart disease in the United States. Occasionally, a defect in the heart's electrical system can cause the heart to beat at a very slow rate. This condition is generally treated with a pacemaker. A pacemaker is a small electrical device that can be surgically implanted to help maintain a regular heartbeat. Pacemakers send electrical signals to stimulate the heart to beat in proper rhythm. They can be programmed to meet the electrical needs of the heart and are now so advanced they can even be programmed to increase heartbeat with exercise and slow the heartbeat once the exercise period is over.
Image by TheVisualMD
Risks of Physical Activity
In general, the benefits of regular physical activity far outweigh risks to the heart and lungs.
Talk with your doctor if you have symptoms such as chest pain or dizziness during physical activity. Rarely do heart problems occur because of physical activity. Examples include arrhythmias, sudden cardiac arrest, and heart attack.
The risk of heart problems due to physical activity is related to your fitness level and the intensity of the activity you're doing. For example, someone who isn't physically fit is at higher risk for a heart attack during vigorous activity than a person who is physically fit.
These events generally happen to people who already have heart conditions.
Youth and young adults who have congenital heart problems are more at risk. The term “congenital” means the heart problem has been present since birth. Congenital heart problems include hypertrophic cardiomyopathy, congenital heart defects, and myocarditis.
Middle-aged and older adults who have coronary heart disease are more likely to have a heart attack when they're exercising vigorously than when they're not.
If you have a heart problem or chronic (ongoing) disease — such as heart disease, diabetes, or high blood pressure — ask your doctor what types of physical activity are safe for you. You can also discuss ways to slowly and safely build physical activity into your daily routine.
Source: National Heart, Lung, and Blood Institute (NHLBI)
Additional Materials (3)
Exercise Safety - Mayo Clinic
Video by Mayo Clinic/YouTube
Intro to Exercise Episode 3: Safety Principles
Video by National Center on Health, Physical Activity and Disability (NCHPAD)/YouTube
How to Stay Safe While Doing 4 Types of Exercise
Video by National Institute on Aging/YouTube
1:54
Exercise Safety - Mayo Clinic
Mayo Clinic/YouTube
4:10
Intro to Exercise Episode 3: Safety Principles
National Center on Health, Physical Activity and Disability (NCHPAD)/YouTube
1:33
How to Stay Safe While Doing 4 Types of Exercise
National Institute on Aging/YouTube
Recommendations for Physical Activity
Mix It Up!
Image by TheVisualMD
Mix It Up!
You need aerobic exercise to strengthen your heart, lungs and stamina. You need anaerobic exercise to increase muscle strength, speed and power. You also need the right mix of stretching, side-to-side movement, activities that are highly challenging and others that are just plain fun! Mixing up your workout routine helps protect you from injury and keeps you motivated to stick with it.
Image by TheVisualMD
Recommendations for Physical Activity
The U.S. Department of Health and Human Services provides physical activity guidelines for all Americans ages 3 and older. The guidelines explain that regular physical activity improves health. They encourage people to be as active as possible for the health benefits. Before getting started with physical activity, read these recommendations to learn about what is best for you.
The guidelines recommend the types and amounts of physical activity that children, adults, older adults, and other groups should do. The guidelines also provide tips for how to fit physical activity into your daily life.
Guidelines for preschool children
The guidelines advise that: (Physical Activity Guidelines, 2018, p47)
Preschool children, ages 3 to 5, should do physical activity throughout the day. A reasonable target may be 3 hours per day of activity of light, moderate, and vigorous intensity.
Adult caregivers should encourage active play that includes different types of activities. This includes unstructured play as well as structured activities, such as throwing games and bicycle or tricycle riding. To strengthen bones, young children should do activities that involve hopping, skipping, jumping, and tumbling.
Guidelines for children and youth
The guidelines advise that:
Children and youth ages 6 to 17 should do 60 minutes or more of physical activity every day. Activities should vary and be a good fit for their age and physical development. Children are naturally active, especially when they're involved in unstructured play (like recess). Any type of activity counts toward the recommended 60 minutes or more.
Most physical activity should be moderate-intensity aerobic activity. Examples include walking, running, skipping, playing on the playground, playing basketball, and biking.
Vigorous-intensity aerobic activity should be included at least 3 days a week. Examples include running, doing jumping jacks, and fast swimming.
Muscle-strengthening activities should be included at least 3 days a week. Examples include playing on playground equipment, playing tug-of-war, and doing pushups and pullups.
Bone-strengthening activities should be included at least 3 days a week. Examples include hopping, skipping, doing jumping jacks, playing volleyball, and working with resistance bands.
Children and youth who have disabilities should work with their doctors to find out what types and amounts of physical activity are safe for them. When possible, these children should meet the recommendations in the guidelines.
Some experts also recommend that children and youth reduce screen time because it limits time for physical activity. They recommend that children aged 2 and older should spend no more than 2 hours a day watching television or using a computer (except for school work).
Guidelines for all adults
The guidelines advise that:
Some physical activity is better than none. Inactive adults should gradually increase their level of activity. People gain health benefits from as little as 60 minutes of moderate-intensity aerobic activity per week.
For major health benefits, do at least 150 minutes (2 hours and 30 minutes) of moderate-intensity aerobic activity or 75 minutes (1 hour and 15 minutes) of vigorous-intensity aerobic activity each week. Another way is to do a combination of both. A general rule is that 2 minutes of moderate-intensity activity counts the same as 1 minute of vigorous-intensity activity.
For even more health benefits, do 300 minutes (5 hours) of moderate-intensity aerobic activity or 150 minutes (2 hours and 30 minutes) of vigorous-intensity activity each week (or a combination of both). The more active you are, the more you will benefit.
Spread the activity throughout the week. Muscle-strengthening activities that are moderate or vigorous intensity should be included 2 or more days a week. These activities should work all the major muscle groups (legs, hips, back, chest, abdomen, shoulders, and arms). Examples include lifting weights, working with resistance bands, and doing situps and pushups, yoga, and heavy gardening.
Additional guidelines for adults aged 65 or older
The guidelines advise that:
Older adults should be physically active. Older adults who do any amount of physical activity gain some health benefits. If inactive, older adults should gradually increase their activity levels and avoid vigorous activity at first.
Older adults should follow the guidelines for adults, if possible. Do a variety of activities, including walking. Walking has been shown to provide health benefits and a low risk of injury.
If you can't do 150 minutes (2 hours and 30 minutes) of activity each week, be as physically active as your abilities and condition allow.
You should do balance exercises if you're at risk for falls, as well as aerobic and bone-strengthening activities. Examples include walking backward or sideways, standing on one leg, and standing from a sitting position several times in a row.
If you have a chronic (ongoing) condition — such as heart disease, lung disease, or diabetes — ask your doctor what types and amounts of activity are safe for you.
Guidelines for pregnancy and soon after delivery
The guidelines advise that:
You should ask your doctor what physical activities are safe to do during pregnancy and after delivery.
If you're healthy but not already active, do at least 150 minutes (2 hours and 30 minutes) of moderate-intensity aerobic activity each week. If possible, spread this activity across the week.
If you're already active, you can continue being active if you stay healthy and talk with your doctor about your activity level throughout your pregnancy.
After the first 3 months of pregnancy, you shouldn't do exercises that involve lying on your back.
You shouldn't do activities in which you might fall or hurt yourself, such as horseback riding, downhill skiing, soccer, and basketball.
Guidelines for other groups
The Physical Activity guidelines also have recommendations for other groups, including people who have disabilities and people who have chronic conditions, such as osteoarthritis, diabetes, and cancer.
Source: National Heart, Lung, and Blood Institute (NHLBI)
Additional Materials (11)
How Much Exercise Should You Get Each Week (According to the Research)?
Video by JAMA Network/YouTube
Physical Activity Guidelines
Video by American Heart Association/YouTube
Guidelines for Physical Activity
Video by Versus Arthritis/YouTube
Let’s get moving! - WHO's Global status report on physical activity 2022
Video by World Health Organization (WHO)/YouTube
Guideline 4 Physical Education and Physical Activity
Video by Centers for Disease Control and Prevention (CDC)/YouTube
Physical Activity Guidelines
Video by Southern Nevada Health District/YouTube
About half of US adults are meeting physical activity guidelines: CDC
Video by ABC News/YouTube
Exercise for Everyone
Most people can begin a program of moderate exercise, such as regular walking and building strength using body weight for resistance. Anyone with arthritis, diabetes, heart disease, liver disease, kidney disease, lung disease or asthma should bring up the subject at a regular physician's appointment before taking on such activities.
Image by TheVisualMD
Exercise for Everyone
Most people can begin a program of moderate exercise, such as regular walking and building strength using body weight for resistance. Anyone with arthritis, diabetes, heart disease, liver disease, kidney disease, lung disease or asthma should bring up the subject at a regular physician`s appointment before taking on such activities.
Image by TheVisualMD
Mix It Up!
You need aerobic exercise to strengthen your heart, lungs and stamina. You need anaerobic exercise to increase muscle strength, speed and power. You also need the right mix of stretching, side-to-side movement, activities that are highly challenging and others that are just plain fun! Mixing up your workout routine helps protect you from injury and keeps you motivated to stick with it.
Image by TheVisualMD
Heart Disease and Alternative Practices
Alternative healing practices such as yoga aids a healthy life. Other ideas that may support the healing process like acupuncture, yoga, massage, and medication.
Image by TheVisualMD
3:25
How Much Exercise Should You Get Each Week (According to the Research)?
JAMA Network/YouTube
2:07
Physical Activity Guidelines
American Heart Association/YouTube
4:06
Guidelines for Physical Activity
Versus Arthritis/YouTube
2:39
Let’s get moving! - WHO's Global status report on physical activity 2022
World Health Organization (WHO)/YouTube
2:25
Guideline 4 Physical Education and Physical Activity
Centers for Disease Control and Prevention (CDC)/YouTube
1:21
Physical Activity Guidelines
Southern Nevada Health District/YouTube
1:05
About half of US adults are meeting physical activity guidelines: CDC
ABC News/YouTube
Exercise for Everyone
TheVisualMD
Exercise for Everyone
TheVisualMD
Mix It Up!
TheVisualMD
Heart Disease and Alternative Practices
TheVisualMD
Getting Started and Staying Active
Woman raking leaves
Image by TheVisualMD
Woman raking leaves
This image features a woman raking leaves on a sunny fall day with her skeletal, muscular, and cardiovascular systems revealed. Though we all require protein in our diet, individual needs differ depending on lifestyle. Those with a sedentary lifestyle, for example, typically need less protein for energy. The Recommended Dietary Allowance (RDA) for protein is 0.8 grams per kilogram or about 0.4 grams per pound of body weight. Protein RDA for competitive athletes increases to about 1.2 - 1.4 grams per kilogram or about 0.6 - 0.7 grams per pound. The increased protein needs are related to increased protein oxidation during exercise (for example, if you weigh 150 pounds, you need about 90 - 105 grams). There are many factors that play into your daily protein requirements, including body weight, level of physical activity, age, gender, rate of growth, other nutrients consumed, genetic makeup, and existing conditions.
Image by TheVisualMD
Getting Started and Staying Active
Physical activity is an important part of a heart healthy lifestyle. To get started and stay active, make physical activity part of your daily routine, keep track of your progress, be active and safe, and talk to your doctor if you have a chronic (ongoing) health condition.
Make physical activity part of your daily routine
You don't have to become a marathon runner to get all the benefits of physical activity. Do activities that you enjoy, and make them part of your daily routine.
If you haven’t been active for a while, start low and build slow. Many people like to start with walking and slowly increase their time and distance. You also can take other steps to make physical activity part of your routine.
Personalize the benefits
People value different things. Some people may highly value the health benefits from physical activity. Others want to be active because they enjoy recreational activities or they want to look better or sleep better.
Some people want to be active because it helps them lose weight or it gives them a chance to spend time with friends. Identify which physical activity benefits you value. This will help you personalize the benefits of physical activity.
Be active with friends and family
Friends and family can help you stay active. For example, go for a hike with a friend. Take dancing lessons with your spouse, or play ball with your child. The possibilities are endless.
Make everyday activities more active
You can make your daily routine more active. For example, take the stairs instead of the elevator. Instead of sending e-mails, walk down the hall to a coworker's office. Rake the leaves instead of using a leaf blower.
Reward yourself with time for physical activity
Sometimes, going for a bike ride or a long walk relieves stress after a long day. Think of physical activity as a special time to refresh your body and mind.
Keep track of your progress
Consider keeping a log of your activity. A log can help you track your progress. Many people like to wear a pedometer (a small device that counts your steps) to track how much they walk every day. These tools can help you set goals and stay motivated.
Be active and safe
Physical activity is safe for almost everyone. You can take steps to make sure it's safe for you too.
Be active on a regular basis to raise your fitness level.
Do activities that fit your health goals and fitness level. Start low and slowly increase your activity level over time. As your fitness improves, you will be able to do physical activities for longer periods and with more intensity.
Spread out your activity over the week and vary the types of activity you do.
Use the right gear and equipment to protect yourself. For example, use bicycle helmets, elbow and knee pads, and goggles.
Be active in safe environments. Pick well-lit and well-maintained places that are clearly separated from car traffic.
Follow safety rules and policies, such as always wearing a helmet when biking.
Make sensible choices about when, where, and how to be active. Consider weather conditions, such as how hot or cold it is, and change your plans as needed.
Talk to your doctor if needed
Healthy people who don't have heart problems don't need to check with a doctor before beginning moderate-intensity activities.
If you have a heart problem or chronic disease, such as heart disease, diabetes, or high blood pressure, talk to your doctor about what types of physical activity are safe for you.
You also should talk to your doctor about safe physical activities if you have symptoms such as chest pain or dizziness.
Source: National Heart, Lung, and Blood Institute (NHLBI)
Additional Materials (7)
This browser does not support the video element.
An Exercise Plan for You
Checking in with your doctor before you start a new fitness regimen is a vital first step. Assess your health and fitness level so you can plan a workout schedule that includes the amounts of aerobic and anaerobic exercise you need. Next, find the activities that you enjoy the most. Your workout should be as enjoyable as possible--that's the best way to ensure that you will stick with your plan. Finally, be sure that you increase the level of intensity in your exercises as you get more fit. Challenge yourself!
Video by TheVisualMD
Ask the Expert: What's the Best Way to Get Started with Exercise?
Video by National Institute on Aging/YouTube
Stay Active at Home - Strength and balance exercises for older adults
Video by Chartered Society of Physiotherapy/YouTube
You Need Aerobic Exercise
Running, swimming, rowing and brisk walking are aerobic exercises, the oxygen-powered activities that strengthen our cardiovascular system, increase our endurance, and burn fat. During aerobic exercise, we use oxygen to efficiently transform nutrients into large amounts of fuel.
Image by TheVisualMD
Taking Care of Our Hearts, Together
Interested in leading a more heart healthy lifestyle? Small steps go a long way especially when you connect with others to stay motivated. This fact sheet suggests several lifestyle changes you can make starting today and ways to get your friends, family, and colleagues involved.
Document by National Heart, Lung, and Blood Institute (NHLBI)
Take Action to Stay Active When You Have Diabetes
Video by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)/YouTube
Tips to stay active during the holidays
Video by BJC Health/YouTube
2:25
An Exercise Plan for You
TheVisualMD
2:10
Ask the Expert: What's the Best Way to Get Started with Exercise?
National Institute on Aging/YouTube
3:56
Stay Active at Home - Strength and balance exercises for older adults
Chartered Society of Physiotherapy/YouTube
You Need Aerobic Exercise
TheVisualMD
Taking Care of Our Hearts, Together
National Heart, Lung, and Blood Institute (NHLBI)
1:05
Take Action to Stay Active When You Have Diabetes
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)/YouTube
2:28
Tips to stay active during the holidays
BJC Health/YouTube
What Are High Blood Triglycerides?
Large Small Intestine Triglycerides and Lipoproteins
Image by TheVisualMD
Large Small Intestine Triglycerides and Lipoproteins
Large Small Intestine Triglycerides and Lipoproteins
Image by TheVisualMD
What Are High Blood Triglycerides?
Your body needs some triglycerides for good health. However, high levels of triglycerides in your blood can raise your risk of heart disease and stroke.
Triglycerides are a type of fat, calledlipid, that circulate in your blood. They are the most common type of fat in your body. Triglycerides come from foods, especially butter, oils, and other fats you eat. Triglycerides also come from extra calories your body does not need right away. Unused calories are stored as triglycerides in fat cells. When your body needs energy, it releases the triglycerides. Some triglycerides are important for good health. However, high triglyceride levels in your blood can raise your risk of heart disease and stroke.
High blood triglycerides are a type of lipid disorder. This condition can develop on its own, with other lipid disorders like high blood cholesterol or low HDL cholesterol, or as part of metabolic syndrome. High blood triglyceride levels are very common. Up to one in four adults are affected. Some health conditions and medicines, genes, and lifestyle habits can raise your risk for high blood triglycerides. Heart-healthy lifestyle changes may lower triglycerides in your blood.
Triglycerides are different from cholesterol. Cholesterol is a waxy, fat-like substance found in all the cells of the body. Levels of triglycerides and blood cholesterol are checked using blood tests.
Source: National Heart, Lung, and Blood Institute (NHLBI)
Additional Materials (2)
Triglycerides - What are Triglycerides - Triglyceride Levels - High Triglycerides
Video by Whats Up Dude/YouTube
Asian Heart Hospital - What is Triglycerides?
Video by Asian Heart Institute/YouTube
2:19
Triglycerides - What are Triglycerides - Triglyceride Levels - High Triglycerides
Whats Up Dude/YouTube
3:11
Asian Heart Hospital - What is Triglycerides?
Asian Heart Institute/YouTube
TLC and Relationships with Healthcare Providers
Step 2: Set Priorities
Image by TheVisualMD
Step 2: Set Priorities
Everyone would like to be the perfect worker, family member, physical specimen and model of mental health and serenity every single day. But in reality, time constraints force us to choose areas of emphasis, and do our imperfect best to improve, bit by bit.
Image by TheVisualMD
TLC and Relationships with Healthcare Providers
Healthcare providers are important partners while treating high cholesterol. The better the communication with healthcare providers, the better the understanding about the treatment and how best to carry it out. This rule also applies to other health professionals who may join the treatment team. Here are some pointers on how to make the partnership work well:
Speak up. If anything is not clear, ask questions and ask for explanations in simple language.
Write it down. Be sure to write down any treatment instructions. If hearing is a challenge, take a friend to the visit.
Keep records. Record test results at each visit.
Review the treatment. Use each visit as a chance to go over the treatment plan. Check goals and make sure everyone is in agreement about next steps.
Be open. If the healthcare provider asks questions, give full and honest answers.
Talk about any challenges while following the TLC Program. Changes can probably be made so the program is easier to follow.
Talk about any symptoms or side effects. If something causes a side effect, briefly say what the symptom is, when it started, how often it happens, and if it’s been getting worse.
Source: National Heart, Lung, and Blood Institute (NHLBI)
Additional Materials (3)
Step 2: Set Priorities
Consider the categories measured by the Gallup organization to track well-being globally over time: physical, financial, career, community and social well-being. You may aim to improve several aspects of your wellness, but don't try to do it all at once. To plan your health-improvement mission, start with the biggest challenge, then decide on a hierarchy for your other goals. It takes a lot of physical and mental energy to live your life in a new way, and each change in your usual routine will pull you out of your comfort zone. Your goal is to improve the way you feel about your life and health. Don't make the mistake of launching a full-scale personal revolution all at once, which could make you feel frustrated and overwhelmed.
Image by TheVisualMD
Step 7: Reach Your Goal
Goal! You have proven that you have the power to change many habits, improve your health and enjoy your life more. Once you have altered your life to reach the goals you set for yourself, the work of maintaining your newfound life balance will go on. For now, be in the moment and savor your success!
Image by TheVisualMD
What Is Joy?
Doctors don't test you for happiness, Some don't even ask about your emotional life. But there is mounting scientific evidence that an entire array of positive emotions and outlook have dramatic health effects--boosting our immunity, cutting our risk of cardiovascular disease and more. Joy encompasses celebratory emotions and a positive outlook on life. When we are happy, when we are optimistic, when our actions are motivated by compassion or love, our health and longevity can improve.
Image by TheVisualMD
Step 2: Set Priorities
TheVisualMD
Step 7: Reach Your Goal
TheVisualMD
What Is Joy?
TheVisualMD
Maintaining a Healthy Weight
Step 5: Learn to Make Good Decisions - The consequences of bad habits
Image by TheVisualMD
Step 5: Learn to Make Good Decisions - The consequences of bad habits
Depending on the change you hope to make, you may be faced with the decision to stay the course or abandon the mission dozens of times a day. How does your brain do it? Learn how to improve your chances of sticking to your new habits.
Image by TheVisualMD
Maintaining a Healthy Weight
Overweight and obesity increase the chances for having high LDL cholesterol and developing high blood pressure, diabetes, heart disease, some cancers, and other serious health problems. Excess weight around the waist also more likely leads to developing metabolic syndrome. Losing any extra weight reduces these risks and improves cholesterol and triglyceride levels. Diet changes and increasing physical activity can get LDL cholesterol and weight under control. At the start of the TLC Program, the main focus will be on lowering LDL cholesterol toward the goal level by making changes such as reducing saturated fat and calories and increasing fiber, which could also help with weight loss.
Source: National Heart, Lung, and Blood Institute (NHLBI)
Additional Materials (4)
Sensitive content
This media may include sensitive content
Overweight man standing
In times of starvation or during a weight-loss regimen, body protein is used to provide energy. Because our bodies do not store protein, functional body proteins such as enzymes and muscle proteins must be broken down to yield amino acids, which can then be used as fuel or to make glucose. Once protein are broken down into amino acids, they can be used as fuel, to make glucose, or to make fatty acids. Excess fatty acids can be stored as triglycerides in the body, thus contributing to weight gain. In a manner of speaking, the body does not want to convert protein to fat. The nutrient is far better suited to the construction and repair of tissues. But when your diet delivers more amino acids than your body needs - a common case among Americans - the excess is stored as glycogen or triglyceride fat. Fat is stored for the purpose of stockpiling energy but, in a sedentary lifestyle, we gain weight because those stockpiles are never called upon. When an oversized hunk of protein (say, 12oz steak instead of a proper 3oz portion) is consumed, insulin arrives in the blood to clear all the excess amino acid. In the presence of insulin, anything you eat is more likely to be converted to body fat.
Image by TheVisualMD
The Consequences of Bad Habits
The brain`s prefrontal cortex, right behind the forehead, manages executive control-the task of choosing a thought or action to meet a goal. The closely linked orbitofrontal cortex and amygdala help regulate decision-making based on the memory of feelings that resulted from past decisions. Our memory forges shortcuts that help us take action without thinking through the consequences.
Image by TheVisualMD
Well-being
Solutions For Health : By embracing the 7 Rules of Health, you can take control of your physical and mental well-being and enjoy greater vitality, better health, and a more fulfilling and satisfying way of life. Visit TheVisualMD's 7 Rules Preview Site.
Image by TheVisualMD
Weight Management & Healthy Living
It’s never too soon or too late to achieve a healthy weight. These tips can help you stay on track today and every day:
Image by NIDDK
Sensitive content
This media may include sensitive content
Overweight man standing
TheVisualMD
The Consequences of Bad Habits
TheVisualMD
Well-being
TheVisualMD
Weight Management & Healthy Living
NIDDK
Heart-Healthy Living — Aim for a Healthy Weight
Cardiovascular Problems of Obesity
Coronary Artery Disease
Plaque Buildup
Stroke
1
2
3
4
Cardiovascular Problems of Obesity
Interactive by TheVisualMD
Cardiovascular Problems of Obesity
Coronary Artery Disease
Plaque Buildup
Stroke
1
2
3
4
Cardiovascular Problems of Obesity
Too much fat in the body damages your blood vessels. About three quarters of obese people die of cardiovascular disease.
Interactive by TheVisualMD
Heart-Healthy Living — Aim for a Healthy Weight
A healthy weight for adults is generally a body mass index (BMI) between 18.5 and 24.9. The online BMI calculator will help you measure your BMI. Download the BMI calculator app for iPhone and Android.
Always talk to your healthcare provider about what your BMI means for you. Talk to your child’s provider to determine if they have a healthy weight, because their BMI should be compared to growth charts specific to age and sex.
Following a heart-healthy eating plan and being physically active are some ways to help you achieve and maintain a healthy weight.
Health risks of overweight or obesity
The more body fat that you have and the more you weigh, the more likely you are to develop heart disease, high blood pressure, type 2 diabetes, breathing problems, and certain cancers.
Learn more about the impacts of overweight and obesity on your heart health.
Measuring waist circumference
If most of your fat is around your waist rather than at your hips, you are at a higher risk for heart disease and type 2 diabetes. A waist circumference of more than 35 inches for women or more than 40 inches for men increases your risk.
To correctly measure your waist circumference, stand and place a tape measure around your middle, just above your hipbones. Measure your waist just after you breathe out.
Benefits of maintaining a healthy weight
If you have been diagnosed with overweight or obesity, it’s important to follow your provider’s recommendations for losing weight. Health professionals recommend losing 5% to 10% of your initial weight over the course of about 6 months. Even before you reach this goal, a loss of just 3% to 5% of your current weight can lower triglyceride and glucose levels in your blood, as well as your risk of developing type 2 diabetes. Losing more than 3% to 5% of your weight can improve blood pressure readings, lower “bad” LDL cholesterol, and increase “good” HDL cholesterol.
Source: National Heart, Lung, and Blood Institute
Additional Materials (25)
The Skinny on Obesity (Ep. 1): An Epidemic for Every Body
Video by UCTVTips/YouTube
Why Do We Overeat?
We get strong cues from the environment and our own bodies to eat while we can.
Image by TheVisualMD
Our Fat Helps Keep Us Fat
Getting rid of body fat, called adipose tissue, is harder than we might realize
Image by TheVisualMD
Obesity: The little things
Video by NHLBI/YouTube
The Power of Cravings
Your senses conspire to make you desire things you know will do you harm. Why?
Image by TheVisualMD
British Heart Foundation - Your weight and heart disease
Video by British Heart Foundation/YouTube
Overweight and Heart Disease, Show Your Heart Some Love
Video by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)/YouTube
Fact or Fiction? Debunking Exercise & Nutrition Myths for Preventing Heart Disease & Risk Factors
Video by Mayo Clinic/YouTube
This browser does not support the video element.
Overweight Boy with Fast Beating Heart
A video of an overweight boy holding his side during a physical education class. It begins as a still with the boy in color while everything else is in gray scale The camera zooms into his chest to view a fast beating heart. When the camera zooms out the scene is in color and the boy continues walking.
Video by TheVisualMD
This browser does not support the video element.
Obesity Epidemic
Top experts talk about why obesity is so strongly linked to the four major causes of death in the US-heart disease, cancer, stroke, and type 2 diabetes. Discover the many disorders associated with obesity: infertility, back pain, Alzheimer's disease, sleep apnea, and more. Find out what your BMI is and why it matters. You'll see why our bodies aren't suited to our modern way of life. Learn how we respond to the wrong cues when we eat and ignore our natural, internal cues. Journey inside your blood vessels and see, on a microscopic level, exactly what happens when you overeat. Witness how fat cells transform from tiny individual cells into a massive tissue. How do we change the tide? Dieting is not the answer! You'll find out how to make little changes in your life that add up to big ones.
Video by TheVisualMD
This browser does not support the video element.
Sleep and Your Weight
How can interrupted sleep affect weight management? Scientists have found that two important appetite-control hormones, leptin and ghrelin, are regulated during our sleep cycles. The hormone ghrelin, produced in the stomach, tells our brain we are hungry. The hormone leptin, manufactured in our fat cells, tells our brain when we've had enough to eat. When sleep is restricted, the hormone ghrelin increases telling us we're still hungry even if we've had enough to eat. The hormone leptin decreases, so it takes longer to get the message when we're full. This imbalance can result in overeating and weight gain.
Video by TheVisualMD
This browser does not support the video element.
Children & Weight Management
It's predicted that kids of the current generation will be the first to have shorter lifespans than their parents because of obesity and its related disorders. The best way to beat obesity is to prevent it, because preventing obesity is much easier than curing it. But if your child is obese, start doing something about it now. Tackling obesity early on, while your child is still young, can prevent many or all of its devastating effects.
Video by TheVisualMD
This browser does not support the video element.
Weight Gain & Back Pain
Stress can contribute to, or possibly even cause, back pain. People with unmanaged stress may unconsciously tighten their back muscles, and over time this may result in muscle stiffness or spasm. Some researchers think that stress can also cause constriction in the back’s blood vessels that results in lack of oxygen supply to the soft tissues (like muscles, tendons, ligaments, and nerves), creating tension, spasm, and pain in the area.Poor posture, like hunching over a keyboard or steering wheel for long periods of time, may not cause back pain, but it does increase your risk for back pain if your back has previously been strained or injured. Being overweight, and especially having a big belly, may increase your risk by straining your back. If you are carrying a lot of weight in your abdomen you probably have weak abdominal muscles, and this lack of muscle support can lead to back pain.
Video by TheVisualMD
Overweight World - Obesity Facts and Statistics
Video by The Infographics Show/YouTube
Lose Weight
For people who are overweight or obese, losing weight helps to relieve sleep apnea. Even a small amount of weight loss can help, and a large amount of weight loss often cures the condition completely. For years, doctors have had anecdotal evidence that weight loss relieved or cured sleep apnea and have advised their patients with sleep apnea to lose weight. There were few studies, though, to show whether the recommended amount of weight loss—about 10% of body weight—was enough to make a difference. However, in 2009, a study of 264 obese or overweight adults with OSA was conducted by the Center for Obesity Research and Education and researchers from six universities. The study showed both doctors and participants that weight loss significantly benefits sleep apnea. Study participants were split into two groups. The first group entered a behavioral weight-loss program that included portion-controlled diets and a prescribed exercise regimen of 175 minutes per week. The second group simply attended several informational seminars.
Image by TheVisualMD
Sleep Fights Weight Gain
Your appetite control hormones and metabolism are thrown off balance when you don't get enough sleep.
Image by TheVisualMD
Sleep Fights Weight Gain
Your appetite control hormones and metabolism are thrown off balance when you don't get enough sleep.
Image by TheVisualMD
Weight Management
Anyone with prediabetes or diabetes who is overweight has a number of excellent reasons to lose weight. If blood glucose levels are high but diabetes hasn`t yet developed, losing just 5-10% of body weight significantly reduces blood sugar levels by changing cells` responsiveness to insulin. For someone who weighs 200 lbs, that`s as little as 10 lbs. If losing weight is combined with exercising, the risk of developing diabetes is cut by 58%. The loss of even a modest amount of weight may allow some people to stop taking their glucose-control medications.
Image by TheVisualMD
Sensitive content
This media may include sensitive content
Overweight man standing
In times of starvation or during a weight-loss regimen, body protein is used to provide energy. Because our bodies do not store protein, functional body proteins such as enzymes and muscle proteins must be broken down to yield amino acids, which can then be used as fuel or to make glucose. Once protein are broken down into amino acids, they can be used as fuel, to make glucose, or to make fatty acids. Excess fatty acids can be stored as triglycerides in the body, thus contributing to weight gain. In a manner of speaking, the body does not want to convert protein to fat. The nutrient is far better suited to the construction and repair of tissues. But when your diet delivers more amino acids than your body needs - a common case among Americans - the excess is stored as glycogen or triglyceride fat. Fat is stored for the purpose of stockpiling energy but, in a sedentary lifestyle, we gain weight because those stockpiles are never called upon. When an oversized hunk of protein (say, 12oz steak instead of a proper 3oz portion) is consumed, insulin arrives in the blood to clear all the excess amino acid. In the presence of insulin, anything you eat is more likely to be converted to body fat.
Image by TheVisualMD
Extruded Fat / Coronal View
Extruding Visceral Fat
Visceral fat is a type of body fat that’s stored within the abdominal cavity. It’s located near several vital organs, including the: liver, stomach, intestines. It can also build up in the arteries.
Interactive by TheVisualMD
Obese man with visible Anatomy Eating a Cookie
Obese man with visible Cardiovascular System Eating a Cookie
Obese man with visible Pancreas Eating a Cookie
Obese man with visible Brain Eating a Cookie
1
2
3
4
Obesity, diabetes, and hypertension effect every system and cell in your body
An obese man in a black t-shirt is shown eating a cookie. Some of his anatomy is faintly visible, including his brain, cardiovascular system, pancreas, liver, and adipose tissue. The image introduces a series of facts on the damaging effects of eating too much sugar.
Interactive by TheVisualMD
Weight Loss Surgery
Because diabetes damages blood vessels throughout the body and so can cause many different complications, people with diabetes may need to take medications to treat or prevent the complications as well as the diabetes. Medications might include:
Image by TheVisualMD
Before - Obese man lifting weights / After - Man lifting weights after weight loss
Exercise Helps Rebuild the Body
Your body is a never-ending construction project. As you read this, old cells in your bones are being broken down and replaced by new ones. Neurons in your brain are making new connections based on information taken in by your senses. When you exercise, muscle cells repair themselves and grow stronger. Nature's regenerative processes are amazing, but remember: You are the foreman of this construction project. Choosing the right combination of aerobic and anaerobic exercise and sticking with your plan will help build a better you. See how exercise builds muscle and helps burn fat.
Interactive by TheVisualMD
Break the Cycle and Peel the Layers of Fat Off 1
Break the Cycle and Peel the Layers of Fat Off 2
Break the Cycle and Peel the Layers of Fat Off 3
1
2
3
Break the Cycle and Peel the Layers of Fat Off
Break the Cycle and Peel the Layers of Fat Off
Interactive by TheVisualMD
Cross Section of African American male abdomen exposing extracorporeal fat and toxic visceral fat / Cross Section of abdomen exposing extracorporeal fat and toxic visceral fat
Cross Section of abdomen exposing extracorporeal fat and toxic visceral fat
Overweight and obesity are the primary risk factors for diabetes, especially if body fat is concentrated in the abdominal area. No fewer than 90% of people with type 2 diabetes are obese or overweight. Obesity is the most common cause of insulin resistance: the more adipose (fatty) tissue someone carries, the more resistant his or her cells become to insulin. The National Institutes of Health (NIH) and other health organizations as have defined obesity as a body mass index (BMI) of 30 and above. A BMI of 30 is about 30 pounds overweight.
Interactive by TheVisualMD
12:16
The Skinny on Obesity (Ep. 1): An Epidemic for Every Body
UCTVTips/YouTube
Why Do We Overeat?
TheVisualMD
Our Fat Helps Keep Us Fat
TheVisualMD
1:14
Obesity: The little things
NHLBI/YouTube
The Power of Cravings
TheVisualMD
6:51
British Heart Foundation - Your weight and heart disease
British Heart Foundation/YouTube
1:05
Overweight and Heart Disease, Show Your Heart Some Love
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)/YouTube
5:11
Fact or Fiction? Debunking Exercise & Nutrition Myths for Preventing Heart Disease & Risk Factors
Mayo Clinic/YouTube
0:17
Overweight Boy with Fast Beating Heart
TheVisualMD
4:43
Obesity Epidemic
TheVisualMD
1:02
Sleep and Your Weight
TheVisualMD
0:59
Children & Weight Management
TheVisualMD
0:20
Weight Gain & Back Pain
TheVisualMD
2:20
Overweight World - Obesity Facts and Statistics
The Infographics Show/YouTube
Lose Weight
TheVisualMD
Sleep Fights Weight Gain
TheVisualMD
Sleep Fights Weight Gain
TheVisualMD
Weight Management
TheVisualMD
Sensitive content
This media may include sensitive content
Overweight man standing
TheVisualMD
Extruding Visceral Fat
TheVisualMD
Obesity, diabetes, and hypertension effect every system and cell in your body
TheVisualMD
Weight Loss Surgery
TheVisualMD
Exercise Helps Rebuild the Body
TheVisualMD
Break the Cycle and Peel the Layers of Fat Off
TheVisualMD
Cross Section of abdomen exposing extracorporeal fat and toxic visceral fat
TheVisualMD
Living the TLC Lifestyle
Heart Healthy Lifestyle
Image by StoryMD
Heart Healthy Lifestyle
Image by StoryMD
Living the TLC Lifestyle
Making lifestyle changes is never easy, but adopting the TLC Program can help people live healthier, longer lives by lowering cholesterol and other risk factors and reducing the risk for heart disease. Some tips to increase chances for success include:
Keep track of changes by starting a TLC diary to record food intake, physical activity, and weight. A diary can also help healthcare providers assess progress.
Set SMART goals to make changes, like walking an extra 2,000 steps each day or adding a new vegetable to one meal each week. SMART goals are Specific, Measured, Appropriate, Realistic, and Time-Bound.
Create a reward when achieving a goal, but not with food.
Source: National Heart, Lung, and Blood Institute (NHLBI)
Additional Materials (1)
Know the Difference Fact Sheet
Cardiovascular disease, heart disease, and coronary heart disease may sound similar but they are not one in the same. This fact sheet will help you understand how these conditions differ.
Document by National Heart, Lung, and Blood Institute (NHLBI)
Know the Difference Fact Sheet
National Heart, Lung, and Blood Institute (NHLBI)
Low-Cholesterol Diet
Foods to Enjoy
Image by TheVisualMD
Foods to Enjoy
Image by TheVisualMD
Low-Cholesterol Diet
High blood cholesterol can affect anyone. It’s a serious condition that increases the risk for heart disease, the number one killer of Americans—women and men. The higher your blood cholesterol level, the greater your risk.
Fortunately, if you have high blood cholesterol, there are steps you can take to lower it and protect your health.
Source: National Heart, Lung, and Blood Institute (NHLBI)
Additional Materials (13)
Controlling Cholesterol
Doctors generally recommend lifestyle changes as the first line of defense against cholesterol levels and atherosclerosis. In addition, one or more of the following drugs may be prescribed:
Image by TheVisualMD
Vegetables, Vegetable Basket, Harvest
Image by congerdesign/Pixabay
Best foods to lower cholesterol. Proper nutrition to lower cholesterol
Video by Paramed/YouTube
Low Carb & Keto: What about Cholesterol?
Video by What I've Learned/YouTube
What is LDL Cholesterol? | Dr.Berg on LDL Bad Cholesterol - Part 4
Video by Dr. Eric Berg DC/YouTube
New Federal Diet Guidelines: More Cholesterol & Coffee For A Healthy Diet? | NBC Nightly News
Video by NBC News/YouTube
Lower your LDL cholesterol on a low carb or keto diet
Video by Diet Doctor/YouTube
Cholesterol in diet advice overturned in U.S.
Video by CBC News: The National/YouTube
Mediterranean Diet Trumps Low-fat Diet for Diabetes Management
Video by American College of Physicians/YouTube
Cholesterol is made by your own body
Cholesterol is made by your own body. It is also found in food products derived from animals. Cholesterol is used to make bile acids in the liver, necessary for fat digestion. Cholesterol is constantly transported in the bloodstream between the liver and all the body's tissues. HDL-cholesterol helps clear excess cholesterol from your body. LDL-cholesterol is ingested by cells in need of cholesterol. LDL particles of the Pattern A type are larger and less dense and may be harmless. LDL particles of the Pattern B type, however, are smaller and more dense and can penetrate through the lining of an artery and into its interior. Oxidized LDL particles (oxLDL) can cause major damage.
Image by TheVisualMD
Aerobic athletes in general, particularly lean ones, have lower LDL (or "bad" cholesterol) levels
There are many factors that can potentially influence cholesterol levels. Exercise may be an important one, though evidence is not definitive; studies have shown that endurance athletes have higher HDL (or \"good\" cholesterol) levels, and aerobic athletes in general, particularly lean ones, have lower LDL (or \"bad\" cholesterol) levels.
Image by TheVisualMD
Cholesterol is Not a Fat
Cholesterol is Not a Fat : Many people think cholesterol is a fat-but it`s not. Cholesterol is a lipid. Unlike fats, which pack a caloric wallop, cholesterol contains zero calories. You couldn`t live without cholesterol: it holds cell membranes together, is a vital part of adrenal and sex hormones, and helps your body make vitamin D.
Image by TheVisualMD
Two Sources of Cholesterol
Two Sources of Cholesterol: You Eat It & You Make It : We know that dietary fats are essential. But before your body can put these fats to use, they must somehow get from your digestive system into your cells. This isn`t as simple as it sounds because fats and blood, like oil and water, do not mix. The body gets around this basic chemistry problem by packaging fat and cholesterol into protein-covered particles that mix easily with blood and flow with it. The cholesterol helps to stabilize the particles, and the size and density of the lipoprotein (from the Greek lipos, for fat) determines whether its cholesterol is classified as "good" or "bad." High-density lipoproteins (HDL), also known as "good" cholesterol, are small, dense, protein-rich lipoproteins; low-density lipoproteins (LDL), also known as "bad" cholesterol, are larger, lighter, and fluffier lipoproteins that form plaque deposits and clog arteries.
Image by TheVisualMD
Controlling Cholesterol
TheVisualMD
Vegetables, Vegetable Basket, Harvest
congerdesign/Pixabay
4:05
Best foods to lower cholesterol. Proper nutrition to lower cholesterol
Paramed/YouTube
12:36
Low Carb & Keto: What about Cholesterol?
What I've Learned/YouTube
11:59
What is LDL Cholesterol? | Dr.Berg on LDL Bad Cholesterol - Part 4
Dr. Eric Berg DC/YouTube
1:55
New Federal Diet Guidelines: More Cholesterol & Coffee For A Healthy Diet? | NBC Nightly News
NBC News/YouTube
3:49
Lower your LDL cholesterol on a low carb or keto diet
Diet Doctor/YouTube
2:43
Cholesterol in diet advice overturned in U.S.
CBC News: The National/YouTube
1:47
Mediterranean Diet Trumps Low-fat Diet for Diabetes Management
American College of Physicians/YouTube
Cholesterol is made by your own body
TheVisualMD
Aerobic athletes in general, particularly lean ones, have lower LDL (or "bad" cholesterol) levels
TheVisualMD
Cholesterol is Not a Fat
TheVisualMD
Two Sources of Cholesterol
TheVisualMD
Your Guide to Lowering Cholesterol With Therapeutic Lifestyle Changes (TLC)
Your Guide to Lowering Cholesterol With Therapeutic Lifestyle Changes (TLC)
Document by National Heart, Lung, and Blood Institute (NHLBI)
Your Guide to Lowering Cholesterol With Therapeutic Lifestyle Changes (TLC)
Need to lower your cholesterol? TLC (therapeutic lifestyle changes) is a set of tools you can use to get results. This easy-to-read booklet is designed to help you make the lifestyle changes that will lower blood cholesterol and reduce your risk for heart disease. It explains how to follow the TLC diet (low in saturated fat, trans fat, and dietary cholesterol), increase physical activity, and manage weight for people whose cholesterol level is above their goal. The guide includes helpful lists and charts, sample menus, a 10-year coronary heart disease risk calculator, and many tips for success. Make TLC part of your program for heart health.
Document by National Heart, Lung, and Blood Institute (NHLBI)
Your Guide to Lowering Cholesterol With Therapeutic Lifestyle Changes (TLC)
Need to lower your cholesterol? TLC (therapeutic lifestyle changes) is a set of tools you can use to get results. This easy-to-read booklet is designed to help you make the lifestyle changes that will lower blood cholesterol and reduce your risk for heart disease. It explains how to follow the TLC diet (low in saturated fat, trans fat, and dietary cholesterol), increase physical activity, and manage weight for people whose cholesterol level is above their goal. The guide includes helpful lists and charts, sample menus, a 10-year coronary heart disease risk calculator, and many tips for success. Make TLC part of your program for heart health.
Source: National Heart, Lung, and Blood Institute (NHLBI)
5 Tips: What You Should Know About High Blood Cholesterol
Keep It Moving
Image by TheVisualMD
Keep It Moving
Image by TheVisualMD
5 Tips: What You Should Know About High Blood Cholesterol
Approximately 13 percent of U.S. adults has high total cholesterol. Lowering cholesterol levels can slow down, reduce, or even stop plaque from building up in the walls of arteries and may decrease the chance of having a heart attack. Mainstays in treating high cholesterol include diet, weight loss, physical activity, and when necessary, drug treatment.
National survey data show that high blood cholesterol is one of the top 10 conditions for which people use complementary health practices such as dietary supplements.
Here are 5 tips about high blood cholesterol:
Work with your health care provider. Ask your health care provider about proven steps you can take to lower your blood cholesterol levels. And be sure to talk with your provider about any complementary health practice you are considering, including dietary supplements. This will help ensure safe and coordinated care.
Change your diet. Saturated fat raises your LDL cholesterol level (often called “bad cholesterol,” the main source of cholesterol buildup and blockage in the arteries) more than anything else in your diet. Diets with too much saturated fat and trans fat are the main cause for high blood cholesterol.
Manage your weight. Losing extra pounds may help lower your LDL and triglycerides (a type of fat found in the blood and in food), while raising your HDL (often called “good cholesterol,” helps keep cholesterol from building up in the arteries).
Get moving. Regular physical activity (such as brisk walking 30 minutes each day) can raise HDL and lower triglycerides, and can help you lose weight and, in that way, help lower your LDL. Aim for a total of at least 150 minutes over the course of a week.
Find out what the science says about dietary supplements marketed for improving cholesterol. The dietary supplements red yeast rice, flaxseed, and garlic, are among the many supplements that have been studied for lowering cholesterol levels. Unfortunately, there isn’t conclusive evidence that any of these supplements are effective in reducing cholesterol levels.
Red yeast rice. Some red yeast rice products contain substances called monacolins, which are produced by the yeast. Monacolin K is chemically identical to the active ingredient in the cholesterol-lowering drug lovastatin, and can cause the same types of side effects and drug interactions as lovastatin. Other red yeast rice products contain little or no monacolin K, and it is not known whether these products have any effect on cholesterol levels. Unfortunately, there is no way to know how much monacolin K is present in most red yeast rice products. Further, the U.S. Food and Drug Administration has determined that red yeast rice products that contain more than trace amounts of monacolin K cannot be sold legally as dietary supplements.
Flaxseed. Studies of flaxseed preparations to lower cholesterol levels report mixed results. A 2009 review of the scientific research of flaxseed for lowering cholesterol found modest improvements in cholesterol, seen more often in postmenopausal women and in people with high initial cholesterol concentrations.
Garlic. Some evidence indicates that taking garlic supplements can slightly lower blood cholesterol levels; however, an NCCIH-funded study on the safety and effectiveness of three garlic preparations (fresh garlic, dried powdered garlic tablets, and aged garlic extract tablets) for lowering blood cholesterol levels found no effect. Although garlic supplements appear to be safe for most adults, they can thin the blood in a manner similar to aspirin, so use caution if you are planning to have surgery or dental work. Garlic supplements have also been found to interfere with the effectiveness of saquinavir, a drug used to treat HIV infection.
Source: National Center for Complementary and Integrative Health (NCCIH)
Additional Materials (17)
Life's Simple 7: Control Cholesterol
Video by American Heart Association/YouTube
Keep Moving!
Exercise and other physical activities should be a regular part of everyone’s life, but it’s especially important if you have asthma. Exercise, especially aerobic exercise, increases your overall fitness as well as the health and strength of your lungs and cardiovascular system. Your sense of well-being is enhanced, too, when you exercise regularly.
Image by TheVisualMD
Keep Moving!
Exercise and other physical activities should be a regular part of everyone’s life, but it’s especially important if you have asthma. Exercise, especially aerobic exercise, increases your overall fitness as well as the health and strength of your lungs and cardiovascular system. Your sense of well-being is enhanced, too, when you exercise regularly.
Image by TheVisualMD
Physical fitness
Keep It Moving : Anerobic means "without oxygen." Anerobic exercise triggers anerobic metabolism, defined as the creation of energy through the combustion of carbohydrates in the absence of oxygen. Anerobic metabolism occurs when the lungs can't put enough oxygen into the bloodstream to keep up with the demands from your muscles for energy. Instead, your muscles use glycogen as fuel. Examples: sprinting, jumping, lifting weights.
Image by TheVisualMD
Healthy Behavior
Image by TheVisualMD
Your blood vessels are the body's superhighway
Your blood vessels are the body's superhighway. Blood races through more than 50,000 miles of vessels, delivering nutrients to cells and hauling waste products away from them. One of the blood's most vital passengers is oxygen. Oxygen binds to hemoglobin, a protein in red blood cells, and is carried to cells throughout the body. Anemia occurs when hemoglobin does not carry enough oxygen to cells. There are several possible causes. Sometimes the body has too little iron, which is essential to the formation of hemoglobin. Deficiencies of vitamin B-12 or folic acid can also cause anemia. Sometimes there are not enough red blood cells, which can result from ulcers or other undetected sources of blood loss. And sometimes the body simply demands more iron for growth: Pregnant women and growing toddlers are at increased risk of anemia. People who are anemic can have headaches, dizziness, difficulty breathing, fatigue and they may feel cold. Anyone who has such symptoms can find out, through a simple blood test, whether some form of anemia is to blame. To keep that superhighway moving, we have to make sure that the blood is doing its job.
Image by TheVisualMD
How to Manage High Cholesterol
Video by American Heart Association/YouTube
Cholesterol Metabolism, LDL, HDL and other Lipoproteins, Animation
Video by Alila Medical Media/YouTube
The Aliseo Family's Story: An End to High Cholesterol
Video by Northwell Health/YouTube
Handling High Cholesterol
Video by LivingHealthyChicago/YouTube
5 Foods That Can Help Lower Cholesterol: Apples, Lentils, Avocados | TODAY
Video by TODAY/YouTube
High Cholesterol - Do I Need To Take Medication?
Video by Talking With Docs/YouTube
3 Foods to Help Lower Cholesterol Naturally
Video by The Doctors/YouTube
Cholesterol Isn't Quite as Bad as You've Been Told
Video by Healthcare Triage/YouTube
'Good' cholesterol: You CAN have too much of a good thing
Video by Sunnybrook Hospital/YouTube
Health: Living With: High Cholesterol -- nytimes.com/video
Video by The New York Times/YouTube
Cholesterol Good and Bad
Video by The National Library of Medicine/YouTube
4:04
Life's Simple 7: Control Cholesterol
American Heart Association/YouTube
Keep Moving!
TheVisualMD
Keep Moving!
TheVisualMD
Physical fitness
TheVisualMD
Healthy Behavior
TheVisualMD
Your blood vessels are the body's superhighway
TheVisualMD
2:56
How to Manage High Cholesterol
American Heart Association/YouTube
3:46
Cholesterol Metabolism, LDL, HDL and other Lipoproteins, Animation
Alila Medical Media/YouTube
3:10
The Aliseo Family's Story: An End to High Cholesterol
Northwell Health/YouTube
5:01
Handling High Cholesterol
LivingHealthyChicago/YouTube
4:25
5 Foods That Can Help Lower Cholesterol: Apples, Lentils, Avocados | TODAY
TODAY/YouTube
11:31
High Cholesterol - Do I Need To Take Medication?
Talking With Docs/YouTube
1:20
3 Foods to Help Lower Cholesterol Naturally
The Doctors/YouTube
5:09
Cholesterol Isn't Quite as Bad as You've Been Told
Healthcare Triage/YouTube
1:59
'Good' cholesterol: You CAN have too much of a good thing
Sunnybrook Hospital/YouTube
6:09
Health: Living With: High Cholesterol -- nytimes.com/video
The New York Times/YouTube
3:01
Cholesterol Good and Bad
The National Library of Medicine/YouTube
How to Lower Cholesterol with Diet
HDL and LDL Cholesterol
Image by StoryMD
HDL and LDL Cholesterol
Cholesterol is shipped between the liver and the body through lipoproteins in your blood. Two types of lipoproteins perform this job: low-density lipoprotein (LDL) and high-density lipoprotein (HDL). You may have heard about “good” and “bad” cholesterol, and this is where these guys come in.
Image by StoryMD
How to Lower Cholesterol with Diet
What is cholesterol?
Your body needs some cholesterol to work properly. But if you have too much in your blood, it can stick to the walls of your arteries and narrow or even block them. This puts you at risk for coronary artery disease and other heart diseases.
Cholesterol travels through the blood on proteins called lipoproteins. One type, LDL, is sometimes called the "bad" cholesterol. A high LDL level leads to a buildup of cholesterol in your arteries. Another type, HDL, is sometimes called the "good" cholesterol. It carries cholesterol from other parts of your body back to your liver. Then your liver removes the cholesterol from your body.
What are the treatments for high cholesterol?
The treatments for high cholesterol are heart-healthy lifestyle changes and medicines. The lifestyle changes include healthy eating, weight management, and regular physical activity.
How can I lower cholesterol with diet?
Heart-healthy lifestyle changes include a diet to lower your cholesterol. The DASH eating plan is one example. Another is the Therapeutic Lifestyle Changes diet, which recommends that you
Choose healthier fats.You should limit both total fat and saturated fat. No more than 25 to 35 percent of your daily calories should come from dietary fats, and less than 7 percent of your daily calories should come from saturated fat. Depending upon how many calories you eat per day, here are the maximum amounts of fats that you should eat:
Calories per Day
Total Fat
Saturated Fat
1,500
42-58 grams
10 grams
2,000
56-78 grams
13 grams
2,500
69-97 grams
17 grams
Saturated fat is a bad fat because it raises your LDL (bad cholesterol) level more than anything else in your diet. It is found in some meats, dairy products, chocolate, baked goods, and deep-fried and processed foods.
Trans fat is another bad fat; it can raise your LDL and lower you HDL (good cholesterol). Trans fat is mostly in foods made with hydrogenated oils and fats, such as stick margarine, crackers, and french fries.
Instead of these bad fats, try healthier fats, such as lean meat, nuts, and unsaturated oils like canola, olive, and safflower oils.
Limit foods with cholesterol. If you are trying to lower your cholesterol, you should have less than 200 mg a day of cholesterol. Cholesterol is in foods of animal origin, such as liver and other organ meats, egg yolks, shrimp, and whole milk dairy products.
Eat plenty of soluble fiber. Foods high in soluble fiber help prevent your digestive tract from absorbing cholesterol. These foods include
Whole-grain cereals such as oatmeal and oat bran
Fruits such as apples, bananas, oranges, pears, and prunes
Legumes such as kidney beans, lentils, chick peas, black-eyed peas, and lima beans
Eat lots of fruits and vegetables. A diet rich in fruits and vegetables can increase important cholesterol-lowering compounds in your diet. These compounds, called plant stanols or sterols, work like soluble fiber.
Eat fish that are high in omega-3 fatty acids. These acids won't lower your LDL level, but they may help raise your HDL level. They may also protect your heart from blood clots and inflammation and reduce your risk of heart attack. Fish that are a good source of omega-3 fatty acids include salmon, tuna (canned or fresh), and mackerel. Try to eat these fish two times a week.
Limit salt. You should try to limit the amount of sodium (salt) that you eat to no more than 2,300 milligrams (about 1 teaspoon of salt) a day. That includes all the sodium you eat, whether it was added in cooking or at the table, or already present in food products. Limiting salt won't lower your cholesterol, but it can lower your risk of heart diseases by helping to lower your blood pressure. You can reduce your sodium by instead choosing low-salt and "no added salt" foods and seasonings at the table or while cooking.
Limit alcohol. Alcohol adds extra calories, which can lead to weight gain. Being overweight can raise your LDL level and lower your HDL level. Too much alcohol can also increase your risk of heart diseases because it can raise your blood pressure and triglyceride level. One drink is a glass of wine, beer, or a small amount of hard liquor, and the recommendation is that
Men should have no more than two drinks containing alcohol a day
Women should have no more than one drink containing alcohol a day
Nutrition labels can help you figure out how much fat, saturated fat, cholesterol, fiber, and sodium is in the foods that you buy.
Source: NIH: National Heart, Lung, and Blood Institute / MedlinePlus
Additional Materials (2)
zero-cholesterol foods
Fruits are zero-cholesterol foods. Fruit on display at La Boqueria market in Barcelona.
Image by Dungodung
Total cholesterol rotation
A test for total cholesterol is an overall measure of “good” as well as “bad” cholesterol. A lipoprotein (from the Greek lipos, for fat) is a fat-and-protein package that enables fats and cholesterol to move freely within the bloodstream (fats and blood, like oil and water, do not mix). Proteins and other components make up the outer shell of the lipoprotein; cholesterol and other fats are packed together inside. The size and density of the lipoprotein determines whether its cholesterol is classified as “good” or “bad.” This interactive features 3 lipoproteins: very high density lipoprotein (VLDL) which is the largest molecule, low-density lipoproteins (LDL) which is the medium-sized molecule, and high-density lipoproteins (HDL), which are the smallest and most dense.
Image by TheVisualMD
zero-cholesterol foods
Dungodung
Total cholesterol rotation
TheVisualMD
Cholesterol Levels: What You Need to Know
Total Cholesterol Rotation (HDL, LDL, and VLDL Molecules)
Image by TheVisualMD
Total Cholesterol Rotation (HDL, LDL, and VLDL Molecules)
A test for total cholesterol is an overall measure of “good” as well as “bad” cholesterol. A lipoprotein (from the Greek lipos, for fat) is a fat-and-protein package that enables fats and cholesterol to move freely within the bloodstream (fats and blood, like oil and water, do not mix). Proteins and other components make up the outer shell of the lipoprotein; cholesterol and other fats are packed together inside. The size and density of the lipoprotein determines whether its cholesterol is classified as “good” or “bad.” This interactive features 3 lipoproteins: very high density lipoprotein (VLDL) which is the largest molecule, low-density lipoproteins (LDL) which is the medium-sized molecule, and high-density lipoproteins (HDL), which are the smallest and most dense.
Image by TheVisualMD
Cholesterol Levels: What You Need to Know
What is cholesterol?
Cholesterol is a waxy, fat-like substance that's found in all the cells in your body. Your liver makes cholesterol, and it is also in some foods, such as meat and dairy products. Your body needs some cholesterol to work properly. But if you have too much cholesterol in your blood, you have a higher risk of coronary artery disease.
How do you measure cholesterol levels?
A blood test called a lipoprotein panel can measure your cholesterol levels. Before the test, you'll need to fast (not eat or drink anything but water) for 9 to 12 hours. The test gives information about your:
Total cholesterol - a measure of the total amount of cholesterol in your blood. It includes both low-density lipoprotein (LDL) cholesterol and high-density lipoprotein (HDL) cholesterol.
LDL (bad) cholesterol - the main source of cholesterol buildup and blockage in the arteries
HDL (good) cholesterol - HDL helps remove cholesterol from your arteries
Non-HDL - this number is your total cholesterol minus your HDL. Your non-HDL includes LDL and other types of cholesterol such as VLDL (very-low-density lipoprotein).
Triglycerides - another form of fat in your blood that can raise your risk for heart disease, especially in women
What do my cholesterol numbers mean?
Cholesterol numbers are measured in milligrams per deciliter (mg/dL). Here are the healthy levels of cholesterol, based on your age and gender:
Anyone age 19 or younger:
Type of Cholesterol
Healthy Level
Total Cholesterol
Less than 170mg/dL
Non-HDL
Less than 120mg/dL
LDL
Less than 100mg/dL
HDL
More than 45mg/dL
Men age 20 or older:
Type of Cholesterol
Healthy Level
Total Cholesterol
125 to 200mg/dL
Non-HDL
Less than 130mg/dL
LDL
Less than 100mg/dL
HDL
40mg/dL or higher
Women age 20 or older:
Type of Cholesterol
Healthy Level
Total Cholesterol
125 to 200mg/dL
Non-HDL
Less than 130mg/dL
LDL
Less than 100mg/dL
HDL
50mg/dL or higher
Triglycerides are not a type of cholesterol, but they are part of a lipoprotein panel (the test that measures cholesterol levels). A normal triglyceride level is below 150 mg/dL. You might need treatment if you have triglyceride levels that are borderline high (150-199 mg/dL) or high (200 mg/dL or more).
How often should I get a cholesterol test?
When and how often you should get a cholesterol test depends on your age, risk factors, and family history. The general recommendations are:
For people who are age 19 or younger::
The first test should be between ages 9 to 11
Children should have the test again every 5 years
Some children may have this test starting at age 2 if there is a family history of high blood cholesterol, heart attack, or stroke
For people who are age 20 or older::
Younger adults should have the test every 5 years
Men ages 45 to 65 and women ages 55 to 65 should have it every 1 to 2 years
What affects my cholesterol levels?
A variety of things can affect cholesterol levels. These are some things you can do to lower your cholesterol levels:
Diet. Saturated fat and cholesterol in the food you eat make your blood cholesterol level rise. Saturated fat is the main problem, but cholesterol in foods also matters. Reducing the amount of saturated fat in your diet helps lower your blood cholesterol level. Foods that have high levels of saturated fats include some meats, dairy products, chocolate, baked goods, and deep-fried and processed foods.
Weight. Being overweight is a risk factor for heart disease. It also tends to increase your cholesterol. Losing weight can help lower your LDL (bad) cholesterol, total cholesterol, and triglyceride levels. It also raises your HDL (good) cholesterol level.
Physical Activity. Not being physically active is a risk factor for heart disease. Regular physical activity can help lower LDL (bad) cholesterol and raise HDL (good) cholesterol levels. It also helps you lose weight. You should try to be physically active for 30 minutes on most, if not all, days.
Smoking. Cigarette smoking lowers your HDL (good) cholesterol. HDL helps to remove bad cholesterol from your arteries. So a lower HDL can contribute to a higher level of bad cholesterol.
Things outside of your control that can also affect cholesterol levels include:
Age and Sex. As women and men get older, their cholesterol levels rise. Before the age of menopause, women have lower total cholesterol levels than men of the same age. After the age of menopause, women's LDL (bad) cholesterol levels tend to rise.
Heredity. Your genes partly determine how much cholesterol your body makes. High blood cholesterol can run in families.
Race. Certain races may have an increased risk of high blood cholesterol. For example, African Americans typically have higher HDL and LDL cholesterol levels than whites.
How can I lower my cholesterol?
There are two main ways to lower your cholesterol:
Heart-healthy lifestyle changes, which include:
Heart-healthy eating. A heart-healthy eating plan limits the amount of saturated and trans fats that you eat. Examples include the Therapeutic Lifestyle Changes diet and the DASH Eating Plan.
Weight Management. If you are overweight, losing weight can help lower your LDL (bad) cholesterol.
Physical Activity. Everyone should get regular physical activity (30 minutes on most, if not all, days).
Managing stress. Research has shown that chronic stress can sometimes raise your LDL cholesterol and lower your HDL cholesterol.
Quitting smoking. Quitting smoking can raise your HDL cholesterol. Since HDL helps to remove LDL cholesterol from your arteries, having more HDL can help to lower your LDL cholesterol.
Drug Treatment. If lifestyle changes alone do not lower your cholesterol enough, you may also need to take medicines. There are several types of cholesterol medicines available, including statins. The medicines work in different ways and can have different side effects. Talk to your health care provider about which one is right for you. While you are taking medicines to lower your cholesterol, you should continue with the lifestyle changes.
Source: NIH: National Heart, Lung, and Blood Institute
Additional Materials (5)
Cholesterol Good and Bad
Video by The National Library of Medicine/YouTube
This browser does not support the video element.
What Is HDL and LDL Cholesterol?
This video explains the difference between HDL and LDL cholesterol. It also reveals what may occur when there are high levels of LDL in the body.LDL may stick to an artery's inner wall causing the build up of plaque, affecting blood flow. When an artery stiffens and constricts, aneurysm, heart attack, and stroke can occur.
Video by TheVisualMD
This browser does not support the video element.
Lipids, Heart Health and Baselining Your Health
Your blood "knows" what you eat, meaning that the cardiovascular system is a sensitive barometer of a person's health, including diet. What individuals eat is reflected in their blood chemistry and the health of their heart, arteries and vessels. Fats (also known as lipids), for example, are vital to health and wellbeing throughout our lives and yet they are mostly associated with obesity and cardiovascular disease. The problem is that not all fats (or cholesterol) are equal. They share basic chemical similarities, but they also have important differences, which, in turn, result in different roles and effects in the body. Tests that offer information on diet and heart health include total cholesterol, low-density lipoprotein (LDL or "bad" cholesterol), high-density lipoprotein (HDL or "good" cholesterol), and triglycerides.
Video by TheVisualMD
This browser does not support the video element.
Refined Carbohydrates and Atherosclerosis
Refined Carbohydrates and Atherosclerosis : In atherosclerosis, hard, fatty deposits called plaque build up inside your arteries. For decades it was thought that eating too many fatty foods, especially foods rich in cholesterol, was to blame for plaque accumulation.
Video by TheVisualMD
This browser does not support the video element.
Cardiovascular Inflammation
Heart disease is the number one killer of men and women in the U.S. The most common cause of heart attack, stroke, and cardiovascular death is atherosclerosis. Atherosclerosis is a chronic inflammatory response in the walls of arteries that leads to the hardening of arterial walls and the buildup of fatty deposits called plaques, or atheromas. Although the process of inflammation can be beneficial in other parts of the body, chronic inflammation within arterial walls is problematic as it seems to promote this underlying growth of plaque. The combination of arterial inflammation and the growth of plaque can lead to the rupture of the plaque, and result in a blood clot. Blood clots can lead to dangerous conditions such as heart attack or stroke.
Video by TheVisualMD
3:01
Cholesterol Good and Bad
The National Library of Medicine/YouTube
0:45
What Is HDL and LDL Cholesterol?
TheVisualMD
2:46
Lipids, Heart Health and Baselining Your Health
TheVisualMD
2:21
Refined Carbohydrates and Atherosclerosis
TheVisualMD
4:26
Cardiovascular Inflammation
TheVisualMD
High Cholesterol Levels
Cardiovascular disease begins in childhood
Image by TheVisualMD
Cardiovascular disease begins in childhood
Obesity in childhood lays the ground for heart and arterial disease. Studies have found that teenagers can develop well-established fatty streaks (the precursors to plaque) in their coronary artery walls, and that even children as young as 10 can have the artery-narrowing plaque that may lead to heart attacks and strokes. Children with high blood cholesterol are likely to remain at risk of elevated blood cholesterol as they grow older.
Image by TheVisualMD
High Cholesterol Levels
Some people have too much cholesterol in their blood. Cholesterol can build up on the inside of the blood vessels in your heart as well as other blood vessels in your body. If too much cholesterol builds up in the blood vessels in your heart, the blood cannot flow through to your heart and may lead to a heart attack. People with high cholesterol, especially high LDL, are more likely to have a heart event, such as a heart attack or stroke, or need surgery or a procedure to open up the blood vessels of the heart (bypass surgery, angioplasty, or stent placement).
A heart-healthy lifestyle may help lower your cholesterol and your chance of having a heart event at all ages. A heart-healthy lifestyle includes reducing the amount of total and saturated fat in your diet, participating in regular aerobic exercise, and losing weight (if you are overweight or obese).
Lowering LDL with certain medicines may decrease your chance of having a heart event. But not everyone with high cholesterol needs medicine. Whether or not you should start a cholesterol-lowering medicine depends on a few things: if you already have heart (cardiovascular) disease, your age, your cholesterol levels, and other factors. Your healthcare provider can help you decide about taking a cholesterol-lowering medicine, such as a statin.
In most cases, if you need to take a cholesterol-lowering medicine, your healthcare provider may consider prescribing a statin first. You can discuss this more with your healthcare provider.
Source: FDA Consumer Health Information
Additional Materials (31)
Artery with Plaque Build Up
Three-dimensional visualization reconstructed from scanned human data. Anterior view of artery with plaque build-up. Plaque build-up is a result of atherosclerosis, a hardening and thickening of the artery walls due to contributing factors such as a high-fat, high-cholesterol diet, age, smoking, and genetics. Atherosclerosis often affects the coronary arteries and can result in clot formation and severe artery blockage that may lead to heart attack or stroke.
Image by TheVisualMD
Depiction of a person suffering from high cholesterol
Depiction of a person suffering from high cholesterol. The typical effects of high cholesterol have been shown.
Image by https://www.myupchar.com/en
Healthy Brain cross section
Brain with Ischemic Stroke cross section
Brain with Hemorrhagic Stroke, cross section
1
2
3
Types of Stroke
Cross Section
1) Healthy Brain - This cross-sectional image through the frontal plane of the head of a healthy individual reveals the temporal and frontal lobes of the brain, along with some major structures visible at this level. The vertebral arteries enter the skull through the foramen magnum. They meet to form the basilar artery, then ultimately branch into the posterior cerebral arteries. The Circle of Willis is a pattern of arteries in the center of the brain, surrounding the pituitary gland. The ventricles are fluid-filled cavities in the brain continuous with the central canal of the spinal cord, housing cells that produce and secrete cerebrospinal fluid. This fluid lubricates and has an immunological function.
2) Ischemic Stroke - This cross-sectional image through the frontal plane of the head of a healthy individual reveals the temporal and frontal lobes of the brain, along with some major structures visible at this level. A portion of dead brain tissue can be seen on the individual's left side of the brain near the surface. The dead tissue is due to an ischemic stroke, most likely a result of blockage in an artery to the brain. The blockage can also occur elsewhere in the body, but break apart and travel through the bloodstream, getting caught in the smaller arteries in the brain. Blood is unable to reach the tissue destination, and therefore that tissue becomes necrotic. The cause of blockage in the first place is likely due to fatty deposits in arterial walls, or atherosclerosis.
3) Hemorrhagic Stroke - This cross-sectional image through the frontal plane of the head of a healthy individual reveals the temporal and frontal lobes of the brain, along with some major structures visible at this level. A hemorrhagic stroke has occurred, as indicated by the area of bleeding on the individual's left side of the brain. A hemorrhagic stroke can occur when a vessel weakened by conditions such as an aneurysm or arteriovenous malformation (AVM) ruptures, allowing blood to leak out into the surrounding tissues. These conditions can be congenital, but risks may increase due to high blood pressure, high cholesterol, smoking, and atherosclerosis.
Interactive by TheVisualMD
Normal Capillary Bed / Damaged Capillary Bed
Before - Normal Capillary Bed / After - Damaged Capillary Bed because of Diabetes and Hypertension
1) Normal Capillary Bed - This image shows normal and healthy capillary beds. However, it can be damaged by high blood sugar. High blood sugar stresses and damages cells, especially the filtering capillaries in the kidneys and the capillaries in the back of your eyes. Thus, many diabetics suffer from chronic kidney disease, which then increases their blood pressure. Damage from the high blood sugar compounded with the increasing blood pressure can lead to vision loss. People with diabetes often also have high blood cholesterol that contributes to atherosclerosis, thereby increasing the risk of heart attacks and strokes.
2) Damaged Capillary Bed - This image shows damaged capillaries. High blood sugar stresses and damages cells, especially the filtering capillaries in the kidneys and the capillaries in the back of your eyes. Thus, many diabetics suffer from chronic kidney disease, which then increases their blood pressure. Damage from the high blood sugar compounded with the increasing blood pressure can lead to vision loss. People with diabetes often also have high blood cholesterol that contributes to atherosclerosis, thereby increasing the risk of heart attacks, mini-strokes and strokes.
Interactive by TheVisualMD
Getting to the Heart of Things
The cardiovascular system consists of the heart, the blood vessels, and the blood itself. Blood is mostly made up of plasma and red and white blood cells. But it contains many other substances as well, like platelets, hormones, and nutrients such as glucose. The cardiovascular system distributes these substances throughout the body as needed and collects waste products from your cells for elimination.
Image by TheVisualMD
Hypertriglyceridemia
Fat Levels in Your Blood : One of the breakthroughs in diagnostic medicine was made possible when researchers identified the key fats that circulate through the bloodstream. Researchers eventually conducted large-scale studies that compared health outcomes with populations of people in which cholesterol as well as triglycerides ranged from low to high. The results of these population studies enabled researchers to calculate a person`s risk of developing cardiovascular disease. Today, many patients know their cholesterol and triglyceride levels, just as they know their blood pressure. And in fact, the more thoroughly people understand these numbers and are able to put them into context, the better they will be able to use this knowledge to maintain good health, improve health or lay the groundwork for prevention. According to the American Heart Association: "Everyone over 20 years of age, regardless to previous high cholesterol history, should have a blood cholesterol test at least every 5 years. If you have been diagnosed with high cholesterol, and are controlling it with diet, you should be tested every year. Individuals taking prescription medications to control cholesterol levels, like statin drugs, may need to get their cholesterol tested at least twice a year to not only check cholesterol levels, but to also check liver function.
Image by TheVisualMD
Healthy Heart Tip – Keep Your Cholesterol in Check
Video by Pfizer/YouTube
The Aliseo Family's Story: An End to High Cholesterol
Video by Northwell Health/YouTube
How to Manage High Cholesterol
Video by American Heart Association/YouTube
Health: Living With: High Cholesterol -- nytimes.com/video
Video by The New York Times/YouTube
Sulakhan’s story – high cholesterol
Video by British Heart Foundation/YouTube
High cholesterol to a heart attack – Sulakhan’s story
Video by British Heart Foundation/YouTube
Another threat of high cholesterol: tendon xanthomas
Video by Faculty of Medicine at UBC/YouTube
High Cholesterol with Internal Medicine Specialist Dr. Terry Chambless
Video by Best Docs Network/YouTube
Treatment Options for Children with High Cholesterol
Video by Boston Children's Hospital/YouTube
I Have High Cholesterol.. What Should I Do?
Video by University of California Television (UCTV)/YouTube
High Cholesterol in Children
Video by Boston Children's Hospital/YouTube
Signs & Symptoms of High Cholesterol
Video by ehowhealth/YouTube
VIDEO: High Cholesterol in Women: What You Need to Know
Video by WomenHeartTV/YouTube
British Heart Foundation - High cholesterol and statins, Ali's story
Video by British Heart Foundation/YouTube
British Heart Foundation - High cholesterol and exercise, Karen's story
Video by British Heart Foundation/YouTube
Why Do Children Have High Cholesterol? - Answered by Pediatric Cardiologist Dr. David Drossner
Video by Nicklaus Children's Hospital/YouTube
High Cholesterol Causes
Video by eMedTV/YouTube
High Cholesterol - Do I Need To Take Medication?
Video by Talking With Docs/YouTube
How to Manage High Cholesterol
Video by American Heart Association/YouTube
How to Lower High Cholesterol
Video by Medical City Dallas/YouTube
British Heart Foundation - High Cholesterol, Heart Healthy Series [British Sign Language]
Video by British Heart Foundation/YouTube
Medication for High Cholesterol
Video by Boston Children's Hospital/YouTube
High Cholesterol In 30s, 40s, Increases Later Risk Of Heart Disease
Video by Duke Health/YouTube
Handling High Cholesterol
Video by LivingHealthyChicago/YouTube
This browser does not support the video element.
Cholesterol & Atherosclerosis
While the term technically refers to any disease that affects the cardiovascular system (as used in MeSH), it is usually used to refer to those related to atherosclerosis (arterial disease). Everyone talks about high cholesterol and how bad it is for you. But why is it bad for you? Where does it come from? What's the difference between "good" and "bad" cholesterol? Take a journey inside the body and explore its vessels, as world-renowned doctors explain what cholesterol is all about and how it contributes to hardening of the arteries, a dangerous condition also known as atherosclerosis.
Video by TheVisualMD
Artery with Plaque Build Up
TheVisualMD
Depiction of a person suffering from high cholesterol
https://www.myupchar.com/en
Types of Stroke
TheVisualMD
Before - Normal Capillary Bed / After - Damaged Capillary Bed because of Diabetes and Hypertension
TheVisualMD
Getting to the Heart of Things
TheVisualMD
Hypertriglyceridemia
TheVisualMD
4:28
Healthy Heart Tip – Keep Your Cholesterol in Check
Pfizer/YouTube
3:10
The Aliseo Family's Story: An End to High Cholesterol
Northwell Health/YouTube
2:56
How to Manage High Cholesterol
American Heart Association/YouTube
6:09
Health: Living With: High Cholesterol -- nytimes.com/video
The New York Times/YouTube
3:04
Sulakhan’s story – high cholesterol
British Heart Foundation/YouTube
2:17
High cholesterol to a heart attack – Sulakhan’s story
British Heart Foundation/YouTube
3:38
Another threat of high cholesterol: tendon xanthomas
Faculty of Medicine at UBC/YouTube
2:21
High Cholesterol with Internal Medicine Specialist Dr. Terry Chambless
Best Docs Network/YouTube
0:44
Treatment Options for Children with High Cholesterol
Boston Children's Hospital/YouTube
2:19
I Have High Cholesterol.. What Should I Do?
University of California Television (UCTV)/YouTube
0:39
High Cholesterol in Children
Boston Children's Hospital/YouTube
1:39
Signs & Symptoms of High Cholesterol
ehowhealth/YouTube
7:44
VIDEO: High Cholesterol in Women: What You Need to Know
WomenHeartTV/YouTube
1:31
British Heart Foundation - High cholesterol and statins, Ali's story
British Heart Foundation/YouTube
1:31
British Heart Foundation - High cholesterol and exercise, Karen's story
British Heart Foundation/YouTube
0:43
Why Do Children Have High Cholesterol? - Answered by Pediatric Cardiologist Dr. David Drossner
Nicklaus Children's Hospital/YouTube
1:03
High Cholesterol Causes
eMedTV/YouTube
11:31
High Cholesterol - Do I Need To Take Medication?
Talking With Docs/YouTube
2:55
How to Manage High Cholesterol
American Heart Association/YouTube
0:32
How to Lower High Cholesterol
Medical City Dallas/YouTube
1:50
British Heart Foundation - High Cholesterol, Heart Healthy Series [British Sign Language]
British Heart Foundation/YouTube
0:43
Medication for High Cholesterol
Boston Children's Hospital/YouTube
1:32
High Cholesterol In 30s, 40s, Increases Later Risk Of Heart Disease
Duke Health/YouTube
5:01
Handling High Cholesterol
LivingHealthyChicago/YouTube
3:08
Cholesterol & Atherosclerosis
TheVisualMD
VLDL Cholesterol Test
VLDL Cholesterol Test
Also called: VLDL-C, VLDL, Very Low Density Lipoprotein
VLDL stands for very low-density lipoprotein. Lipoproteins are particles that carry fat in the bloodstream. Like LDL cholesterol, VLDL cholesterol is considered a type of "bad" cholesterol. Testing for VLDL cholesterol can be used to assess a person's cardiovascular risk.
VLDL Cholesterol Test
Also called: VLDL-C, VLDL, Very Low Density Lipoprotein
VLDL stands for very low-density lipoprotein. Lipoproteins are particles that carry fat in the bloodstream. Like LDL cholesterol, VLDL cholesterol is considered a type of "bad" cholesterol. Testing for VLDL cholesterol can be used to assess a person's cardiovascular risk.
{"label":"VLDL Cholesterol Reference Range","scale":"lin","step":0.1,"hideunits":false,"units":[{"printSymbol":"mg\/dL","code":"mg\/dL","name":"milligram per deciliter"}],"items":[{"flag":"normal","label":{"short":"Normal","long":"Normal","orientation":"horizontal"},"values":{"min":0,"max":30},"text":"Normal results may vary based on the laboratory and the method used.","conditions":[]},{"flag":"abnormal","label":{"short":"High","long":"High","orientation":"horizontal"},"values":{"min":30,"max":60},"text":"A high VLDL result indicates that you have an increased risk of developing cardiovascular disease. Talk to your doctor to know what this result means in your specific case.","conditions":["Coronary heart disease","Stroke","Myocardial infarction","Heart attack"]}],"value":15}[{"normal":0},{"abnormal":0}]
Use the slider below to see how your results affect your
health.
mg/dL
30
Your result is Normal.
Normal results may vary based on the laboratory and the method used.
Related conditions
Lipoproteins are the particles that transport fat and lipids (cholesterol and triglycerides) in the bloodstream.VLDL-cholesterol is produced in the liver, and from there it gets released into the blood to provide the body tissues with triglycerides.
Since about half of VLDL particles consist of triglycerides, this kind of structure makes VLDL particles very easy to anchor to the walls of arteries and eventually block the blood flow. These blockages may lead to atherosclerosis and heart disease. Therefore, VLDL-cholesterol is considered to be “bad” cholesterol.
The VLDL-cholesterol (very low-density lipoprotein cholesterol) test is part of a lipid (fats) profile to assess a person's risk for heart disease.
The values of VLDL cholesterol are usually estimated based on the triglyceride values. The calculation to estimate the values are as follows:
Divide the triglyceride value by 5 in case the result is given in mg/dL
Divide the triglyceride value by 2.2 in case the result is given in mmol/L.
Testing for VLDL is mainly done to assess a person's risk of developing atherosclerosis (decreased blood flow through the arteries due to a build-up of cholesterol and lipids) and heart disease.
A VLDL test is not normally used as a screening test; therefore, is not indicated in all cases. However, if you happen to have normal or slightly elevated LDL-C (low-density lipoprotein cholesterol) levels, and you have a personal or family history of heart disease at a young age, your doctor may want to use this test to assess your risk of cardiovascular disease (CVD).
Similarly, if you have certain chronic conditions such as high blood pressure or type 2 diabetes, your doctor may also want to measure your VLDL levels to help determine your CVD risk.
Please note that VLDL is always ordered together with other lipid analysis (total cholesterol, HDL, LDL, and triglycerides).
A needle will be used to draw a small amount of blood from a vein in your arm; this usually takes only a few seconds to be done.
You will need to fast for at least 9 to 12 hours and avoid consuming alcohol for at least 24 hours before the test. Usually, no other special preparations are needed.
The risks are related only to the blood extraction procedure, including a little bleeding, temporary pain or discomfort, bruising, or local infection.
A normal VLDL value is considered to be up to 30 mg/dL or 0.77 mmol/L.
An increased VLDL value indicates that you have an increased risk of developing coronary heart disease (stroke, heart attack). Therefore, you need to change some lifestyle habits to lower your blood lipid levels.
If a person's triglyceride value is higher than 40 mg/dL (4.5 mmol/L), the VLDL calculation does not apply because other lipids can interfere with the result.
There is a possibility to measure VLDL levels directly, but these techniques are expensive and difficult to perform. Therefore, they are mostly used for research purposes.
Doing regular exercise and maintaining a healthy diet normally helps in decreasing the levels of lipids (fats) in the blood.
VLDL Cholesterol. MedlinePlus. [accessed on Oct 31, 2018]
VLDL Cholesterol - Health Encyclopedia - University of Rochester Medical Center [accessed on Oct 31, 2018]
VLDL Cholesterol. Lab Tests Online. [accessed on Oct 31, 2018]
VLDL cholesterol: Is it harmful? Mayo Clinic. [accessed on Oct 31, 2018]
Normal reference ranges can vary depending on the laboratory and the method used for testing. You must use the range supplied by the laboratory that performed your test to evaluate whether your results are "within normal limits."
Additional Materials (17)
What Is HDL and LDL Cholesterol?
This video explains the difference between HDL and LDL cholesterol. It also reveals what may occur when there are high levels of LDL in the body.LDL may stick to an artery's inner wall causing the build up of plaque, affecting blood flow. When an artery stiffens and constricts, aneurysm, heart attack, and stroke can occur.
Image by TheVisualMD
This browser does not support the video element.
Cholesterol & Atherosclerosis
While the term technically refers to any disease that affects the cardiovascular system (as used in MeSH), it is usually used to refer to those related to atherosclerosis (arterial disease). Everyone talks about high cholesterol and how bad it is for you. But why is it bad for you? Where does it come from? What's the difference between "good" and "bad" cholesterol? Take a journey inside the body and explore its vessels, as world-renowned doctors explain what cholesterol is all about and how it contributes to hardening of the arteries, a dangerous condition also known as atherosclerosis.
Video by TheVisualMD
Lipoprotein in the Blood Stream
Lipoprotein in the Blood Stream
Image by TheVisualMD
Lipids
Cross section of the different structures that phospholipids can take in a aqueous solution. The circles are the hydrophilic heads and the wavy lines are the fatty acyl side chains.
Image by Mariana Ruiz Villarreal , LadyofHats
Lipids and Lipoproteins
Lipids and Lipoproteins
Image by TheVisualMD
Chylomicron structure - ApoA, ApoB, ApoC, ApoE (apolipoproteins); T (triacylglycerol); C (cholesterol); green (phospholipids)
Chylomicron structure - ApoA, ApoB, ApoC, ApoE (apolipoproteins); T (triacylglycerol); C (cholesterol); green (phospholipids)
Image by Xvazquez
Total Cholesterol Rotation (HDL, LDL, and VLDL Molecules)
A test for total cholesterol is an overall measure of “good” as well as “bad” cholesterol. A lipoprotein (from the Greek lipos, for fat) is a fat-and-protein package that enables fats and cholesterol to move freely within the bloodstream (fats and blood, like oil and water, do not mix). Proteins and other components make up the outer shell of the lipoprotein; cholesterol and other fats are packed together inside. The size and density of the lipoprotein determines whether its cholesterol is classified as “good” or “bad.” This interactive features 3 lipoproteins: very high density lipoprotein (VLDL) which is the largest molecule, low-density lipoproteins (LDL) which is the medium-sized molecule, and high-density lipoproteins (HDL), which are the smallest and most dense.
Image by TheVisualMD
Controlling Cholesterol
Controlling Cholesterol with Medicine
Image by TheVisualMD
Controlling Cholesterol
Controlling Cholesterol with Medicine
Image by TheVisualMD
Lipid Absorption
Lipid Absorption
Image by OpenStax College
Lipids
The membrane that surrounds a cell is made up of proteins and lipids. Depending on the membrane's location and role in the body, lipids can make up anywhere from 20 to 80 percent of the membrane, with the remainder being proteins. Cholesterol (green), which is not found in plant cells, is a type of lipid that helps stiffen the membrane.
Image by Judith Stoffer - NIH National Institute of General Medical Sciences
Cholesterol pathway
Cholesterol pathway
Image by TheVisualMD
Liver and Lipoproteins
Liver and Lipoproteins
Image by TheVisualMD
Liver and Lipoproteins
Liver and Lipoproteins
Image by TheVisualMD
VLDL
VLDL 1
Image by Servier Medical Art
Dimensions of lipoproteins
Dimensions of lipoproteins
Image by Peter Forster
Lipid Metabolism
Lipid logistics: transport of triglycerides and cholesterol in organisms in form of lipoproteins as chylomicrons, VLDL, LDL, IDL, HDL.
Image by Peter Forster
What Is HDL and LDL Cholesterol?
TheVisualMD
3:08
Cholesterol & Atherosclerosis
TheVisualMD
Lipoprotein in the Blood Stream
TheVisualMD
Lipids
Mariana Ruiz Villarreal , LadyofHats
Lipids and Lipoproteins
TheVisualMD
Chylomicron structure - ApoA, ApoB, ApoC, ApoE (apolipoproteins); T (triacylglycerol); C (cholesterol); green (phospholipids)
Xvazquez
Total Cholesterol Rotation (HDL, LDL, and VLDL Molecules)
TheVisualMD
Controlling Cholesterol
TheVisualMD
Controlling Cholesterol
TheVisualMD
Lipid Absorption
OpenStax College
Lipids
Judith Stoffer - NIH National Institute of General Medical Sciences
Cholesterol pathway
TheVisualMD
Liver and Lipoproteins
TheVisualMD
Liver and Lipoproteins
TheVisualMD
VLDL
Servier Medical Art
Dimensions of lipoproteins
Peter Forster
Lipid Metabolism
Peter Forster
LDL/HDL Ratio
LDL/HDL Ratio
Also called: LDL Cholesterol/HDL Cholesterol Ratio, LDL-C/HDL-C, High-density lipoprotein to Low-density lipoprotein ratio, LDL to HDL ratio, LDL-C:HDL-C
Under certain conditions, the risk of developing coronary heart disease (strokes, heart attack) cannot be properly assessed only by looking at a person’s lipids test results. In these cases, the LDL “bad cholesterol” to HDL “good cholesterol” ratio can be used to assess how high a person's cardiovascular risk is.
LDL/HDL Ratio
Also called: LDL Cholesterol/HDL Cholesterol Ratio, LDL-C/HDL-C, High-density lipoprotein to Low-density lipoprotein ratio, LDL to HDL ratio, LDL-C:HDL-C
Under certain conditions, the risk of developing coronary heart disease (strokes, heart attack) cannot be properly assessed only by looking at a person’s lipids test results. In these cases, the LDL “bad cholesterol” to HDL “good cholesterol” ratio can be used to assess how high a person's cardiovascular risk is.
{"label":"LDL\/HDL Ratio Reference Range","scale":"lin","step":0.1,"hideunits":false,"units":[{"printSymbol":"{ratio}","code":"{ratio}","name":"ratio"}],"items":[{"flag":"normal","label":{"short":"Optimal","long":"Optimal","orientation":"horizontal"},"values":{"min":0,"max":2.5},"text":"You have a low cardiovascular risk. ","conditions":[]},{"flag":"borderline","label":{"short":"Borderline high","long":"Borderline high","orientation":"horizontal"},"values":{"min":2.5,"max":3},"text":"You have a low cardiovascular risk. ","conditions":[]},{"flag":"abnormal","label":{"short":"High","long":"High","orientation":"horizontal"},"values":{"min":3,"max":5},"text":" Your LDL to HDL ratio is considered to be in suboptimal levels, which puts you at risk for developing coronary heart disease.","conditions":["Coronary Heart Disease","Cardiovascular Risk","Heart Attack","Stroke"]}],"value":1.3}[{"normal":0},{"borderline":0},{"abnormal":0}]
Use the slider below to see how your results affect your
health.
{ratio}
2.5
3
Your result is Optimal.
You have a low cardiovascular risk.
Related conditions
Cholesterol is a type of fat (lipid) that is necessary for the maintenance of some body functions, like for instance the production of hormones. Cholesterol travels through the blood attached to certain proteins called lipoproteins.
There are two main types of lipoproteins, which are low-density lipoprotein cholesterol (LDL-C) also known as “bad cholesterol,” and high-density lipoprotein cholesterol (HDL-C) also known as “good cholesterol.”
LDL-C moves cholesterol into your arteries, hence increasing your risk of developing coronary heart disease (CHD); while HDL-C carries away excess cholesterol out of your arteries, therefore decreasing your risk for CHD.
The LDL/HDL ratio is obtained by dividing your levels of LDL cholesterol by your levels of HDL cholesterol.
Total cholesterol, HDL-C, LDL-C, and triglycerides are usually part of a lipid profile test, which is used to monitor and screen for unhealthy levels of fats in the blood.
If you have borderline results or very imbalanced lipid levels (like for instance low LDL-C along with very low HDL-C), your doctor may want to know what your LDL/HDL ratio is, since it can provide more information about your overall CHD risk.
Every person with no risk factors for heart disease should get tested at least every five years as part of a routine check-up. When one or more risk factors for heart disease are associated, the test should be done more frequently.
Risk factors for cardiovascular disease include:
Unbalanced diet
Physical inactivity (sedentarism)
Being overweight or obese
More than 50 years of age in women
More than 45 years of age in men
Cigarette smoking
Diabetes
High blood pressure
Family history of early heart disease
Previously diagnosed heart disease
A small amount of blood will be drawn from a vein in your arm by using a needle.
You will need to fast for at least 9 to 12 hours before the test. Usually, no other special preparations are required.
Only the risks related to blood extraction, which are temporary discomfort, bruising, little bleeding, and risk of infection in the place where the needle was inserted.
A lower number means a lower cardiovascular risk, however the optimal levels vary depending on your age, gender and health history.
Optimal: your cardiovascular risk is considered to be low.
Borderline high: you have a normal LDL to HDL ratio and your cardiovascular risk is considered to be low. However, you may benefit from changing some lifestyle habits to prevent your LDL to HDL ratio from getting higher.
High: your LDL to HDL ratio is considered to be in suboptimal levels, which puts you at risk for developing coronary heart disease (stroke, heart attack). Therefore, you need to change some lifestyle habits to lower it. Ask your healthcare provider what your test results mean in your specific case.
This test is not diagnostic, but it’s rather used to evaluate a person’s risk to develop cardiovascular disease.
When a person’s triglycerides levels exceed 300 mg/dL (3.36 mmol/L), the LDL/HDL ratio is less accurate and therefore, in these cases, it is preferable to use the total/HDL cholesterol ratio.
Lemieux I, Lamarche B, Couillard C, et al. Total Cholesterol/HDL Cholesterol Ratio vs LDL Cholesterol/HDL Cholesterol Ratio as Indices of Ischemic Heart Disease Risk in MenThe Quebec Cardiovascular Study. Arch Intern Med. 2001;161(22):2685–2692. doi:10.1001/archinte.161.22.2685 [accessed on Oct 03, 2018]
Lipoprotein ratios: Physiological significance and clinical usefulness in cardiovascular prevention [accessed on Oct 03, 2018]
235010: Lipid Panel With LDL:HDL Ratio | LabCorp [accessed on Oct 03, 2018]
Total Cholesterol/HDL Cholesterol Ratio vs LDL Cholesterol/HDL Cholesterol Ratio as Indices of Ischemic Heart Disease Risk in Men: The Quebec Cardiovascular Study. | Cardiology | JAMA Internal Medicine | JAMA Network [accessed on Oct 03, 2018]
DEFINE_ME [accessed on Oct 03, 2018]
Normal reference ranges can vary depending on the laboratory and the method used for testing. You must use the range supplied by the laboratory that performed your test to evaluate whether your results are "within normal limits."
Cholesterol Home Test
Cholesterol Home Test
Also called: At-Home Cholesterol Test
By using a home test kit, assessing your cholesterol level can be much easier and simpler. Cholesterol is a fat (lipid) in your blood. High cholesterol increases your risk of heart disease.
Cholesterol Home Test
Also called: At-Home Cholesterol Test
By using a home test kit, assessing your cholesterol level can be much easier and simpler. Cholesterol is a fat (lipid) in your blood. High cholesterol increases your risk of heart disease.
{"label":"Cholesterol Home Test Reference Range","scale":"lin","step":0.1,"hideunits":false,"units":[{"printSymbol":"mg\/dL","code":"mg\/dL","name":"milligram per deciliter"}],"items":[{"flag":"normal","label":{"short":"Desirable","long":"Desirable","orientation":"horizontal"},"values":{"min":125,"max":200},"text":"While cholesterol levels can vary widely among healthy individuals, total cholesterol levels below 200 milligrams per deciliter (mg\/dL) are considered most desirable.","conditions":[]},{"flag":"abnormal","label":{"short":"High","long":"High","orientation":"horizontal"},"values":{"min":200,"max":400},"text":"Talk to your doctor if your test shows that your cholesterol is higher than 200 mg\/dL. Many things can cause high cholesterol levels including diet, exercise, and other factors. Your doctor may want you to test your cholesterol again.","conditions":[]}],"value":162.5}[{"normal":0},{"abnormal":0}]
Use the slider below to see how your results affect your
health.
mg/dL
200
Your result is Desirable.
While cholesterol levels can vary widely among healthy individuals, total cholesterol levels below 200 milligrams per deciliter (mg/dL) are considered most desirable.
Related conditions
This is a home-use test kit to measure total cholesterol.
Cholesterol is a fat (lipid) in your blood. High-density lipoprotein (HDL) ("good" cholesterol) helps protect your heart, but low-density lipoprotein (LDL) ("bad" cholesterol) can clog the arteries of your heart. Some cholesterol tests also measure triglycerides, another type of fat in the blood.
This is a quantitative test—you find out the amount of total cholesterol present in your sample.
You should do this test to find out if you have high total cholesterol. High cholesterol increases your risk of heart disease. When the blood vessels of your heart become clogged by cholesterol, your heart does not receive enough oxygen. This can cause heart disease.
If you are more than 20 years old, you should test your cholesterol about every 5 years. If your doctor has you on a special diet or drugs to control your cholesterol, you may need to check your cholesterol more frequently. Follow your doctor's recommendations about how often you test your cholesterol.
Your total cholesterol level should be 200 mg/dL or less, according to recommendations in the National Cholesterol Education Program (NCEP) Third Adult Treatment Panel (ATP III). You should try to keep your LDL values less than 100 mg/dL, your HDL values greater or equal to 40 mg/dL, and your triglyceride values less than 150 mg/dL.
This test is about as accurate as the test your doctor uses, but you must follow the directions carefully.
Total cholesterol tests vary in accuracy from brand to brand. Information about the test's accuracy is printed on its package. Tests that say they are "traceable" to a program of the Centers for Disease Control and Prevention (CDC) may be more accurate than others.
Talk to your doctor if your test shows that your cholesterol is higher than 200 mg/dL. Many things can cause high cholesterol levels including diet, exercise, and other factors. Your doctor may want you to test your cholesterol again.
You prick your finger with a lancet to get a drop of blood. Then put the drop of blood on a piece paper that contains special chemicals. The paper will change color depending on how much cholesterol is in your blood. Some testing kits use a small machine to tell you how much cholesterol there is in the sample.
Questions and answers about the home-use test kit to measure total cholesterol. U.S. Food and Drug Administration. [accessed on Feb 04, 2018]
Normal reference ranges can vary depending on the laboratory and the method used for testing. You must use the range supplied by the laboratory that performed your test to evaluate whether your results are "within normal limits."
Cholesterol Test
Cholesterol Test
Also called: Cholesterol Levels, Blood Cholesterol, Total Cholesterol
A cholesterol test is a blood test that measures the amount of each type of cholesterol and certain fats in your blood. High cholesterol can put you at risk for heart disease.
Cholesterol Test
Also called: Cholesterol Levels, Blood Cholesterol, Total Cholesterol
A cholesterol test is a blood test that measures the amount of each type of cholesterol and certain fats in your blood. High cholesterol can put you at risk for heart disease.
{"label":"Total Cholesterol Reference Range","scale":"lin","step":0.1,"hideunits":false,"units":[{"printSymbol":"mg\/dL","code":"mg\/dL","name":"milligram per deciliter"}],"items":[{"flag":"normal","label":{"short":"Desirable","long":"Desirable","orientation":"horizontal"},"values":{"min":125,"max":200},"text":"While cholesterol levels can vary widely among healthy individuals, total cholesterol levels below 200 milligrams per deciliter (mg\/dL) are considered most desirable.","conditions":[]},{"flag":"borderline","label":{"short":"Borderline","long":"Borderline","orientation":"horizontal"},"values":{"min":200,"max":240},"text":"","conditions":[]},{"flag":"abnormal","label":{"short":"High","long":"High","orientation":"horizontal"},"values":{"min":240,"max":400},"text":"Total cholesterol levels of 240 mg\/dL and higher may put people at high risk for cardiovascular disease.","conditions":["Hypercholesterolemia","Cardiovascular disease","Diabetes","Biliary cirrhosis","High-fat diet","Familial hyperlipidemia"]}],"value":162.5}[{"normal":0},{"borderline":0},{"abnormal":0}]
Use the slider below to see how your results affect your
health.
mg/dL
200
240
Your result is Desirable.
While cholesterol levels can vary widely among healthy individuals, total cholesterol levels below 200 milligrams per deciliter (mg/dL) are considered most desirable.
Related conditions
Cholesterol is a waxy, fat-like substance that's found in your blood and every cell of your body. You need some cholesterol to keep your cells and organs healthy. Your liver makes all the cholesterol your body needs. But you can also get cholesterol from the foods you eat, especially meat, eggs, poultry, and dairy products. Foods that are high in dietary fat can also make your liver produce more cholesterol.
There are two main types of cholesterol: low-density lipoprotein (LDL), or "bad" cholesterol, and high-density lipoprotein (HDL), or "good" cholesterol. A cholesterol test is a blood test that measures the amount of each type of cholesterol and certain fats in your blood.
Too much LDL cholesterol in your blood may put you at risk for heart disease and other serious conditions. High LDL levels can cause the build-up of plaque, a fatty substance that narrows the arteries and blocks blood from flowing normally. When blood flow to the heart is blocked, it can cause a heart attack. When blood flow to the brain is blocked, it can lead to stroke and peripheral artery disease.
If you have high cholesterol, you may not experience any symptoms at all, but you could be at significant risk for heart disease. A cholesterol test can give your health care provider important information about the cholesterol levels in your blood. The test measures:
LDL levels. Also known as the "bad" cholesterol, LDL is the main source of blockages in the arteries.
HDL levels. Considered the "good" cholesterol, HDL helps get rid of "bad" LDL cholesterol.
Total cholesterol. The combined amount of low-density lipoprotein (LDL) cholesterol and high-density lipoprotein (HDL) cholesterol in your blood.
Triglycerides A type of fat found in your blood. According to some studies, high levels of triglycerides may increase the risk of heart disease, especially in women.
VLDL levels. Very low-density lipoprotein (VLDL) is another type of "bad" cholesterol. Development of plaque on the arteries has been linked to high VLDL levels. It's not easy to measure VLDL, so most of the time these levels are estimated based on triglyceride measurements.
Your doctor may order a cholesterol test as part of a routine exam, or if you have a family history of heart disease or one or more of the following risk factors:
High blood pressure
Type 2 diabetes
Smoking
Excess weight or obesity
Lack of physical activity
A diet high in saturated fat
Your age may also be a factor, because your risk for heart disease increases as you get older.
A health care professional will take a blood sample from a vein in your arm, using a small needle. After the needle is inserted, a small amount of blood will be collected into a test tube or vial. You may feel a little sting when the needle goes in or out. This usually takes less than five minutes.
Cholesterol tests are usually done in the morning, as you may be asked to refrain from eating for several hours prior to the test.
You may also be able to use an at-home kit to test for cholesterol. While instructions may vary between brands, your kit will include some kind of device to prick your finger. You’ll use this device to collect a drop of blood for testing. Be sure to follow the kit instructions carefully.
Also, be sure to tell your health care provider if your at-home test results shown your cholesterol level is higher than 200 mg/dl.
You may need to fast--no food or drink--for 9 to 12 hours before your blood is drawn. Your health care provider will let you know if you need to fast and if there are any special instructions to follow.
There is very little risk to having a blood test. You may have slight pain or bruising at the spot where the needle was put in, but most symptoms go away quickly.
Cholesterol is usually measured in milligrams (mg) of cholesterol per deciliter (dL) of blood. The information below shows how the different types of cholesterol measurements are categorized.
Total Cholesterol Level
Category
Less than 200mg/dL
Desirable
200-239 mg/dL
Borderline high
240mg/dL and above
High
LDL (Bad) Cholesterol Level
LDL Cholesterol Category
Less than 100mg/dL
Optimal
100-129mg/dL
Near optimal/above optimal
130-159 mg/dL
Borderline high
160-189 mg/dL
High
190 mg/dL and above
Very High
HDL (Good) Cholesterol Level
HDL Cholesterol Category
60 mg/dL and higher
Considered protective against heart disease
40-59 mg/dL
The higher, the better
Less than 40 mg/dL
A major risk factor for heart disease
A healthy cholesterol range for you may depend on your age, family history, lifestyle, and other risk factors. In general, low LDL levels and high HDL cholesterol levels are good for heart health. High levels of triglycerides may also put you at risk for heart disease.
The LDL on your results may say "calculated" which means it includes a calculation of total cholesterol, HDL, and triglycerides. Your LDL level may also be measured "directly," without using other measurements. Regardless, you want your LDL number to be low.
High cholesterol can lead to heart disease, the number one cause of death in the United States. While some risk factors for cholesterol, such as age and heredity, are beyond your control, there are actions you can take to lower your LDL levels and reduce your risk, including:
Eating a healthy diet. Reducing or avoiding foods high in saturated fat and cholesterol can help reduce the cholesterol levels in your blood.
Losing weight. Being overweight can increase your cholesterol and risk for heart disease.
Staying active. Regular exercise may help lower your LDL (bad) cholesterol levels and raise your HDL (good) cholesterol levels. It may also help you lose weight.
Talk to your health care provider before making any major change in your diet or exercise routine.
Normal reference ranges can vary depending on the laboratory and the method used for testing. You must use the range supplied by the laboratory that performed your test to evaluate whether your results are "within normal limits."
Additional Materials (12)
Total Cholesterol: Heart
The heart beats about 100,000 times a day, pumping blood through a vast system of arteries, veins and microscopic capillaries. While many risk factors for cardiovascular disease, including cholesterol levels, are related to lifestyle, others are largely genetic.
Image by TheVisualMD
Total Cholesterol: Heart and Liver
The liver produces most of the body's cholesterol in order to package fats in the form of lipoproteins. HDL is referred to as \"good\" cholesterol because it picks up excess cholesterol in the bloodstream and carries it back to the liver for disposal.
Image by TheVisualMD
Total Cholesterol: Thrombus
Thrombosis is the formation of a blood clot (thrombus) inside a blood vessel. If the clot is large or persistent enough, it can obstruct blood flow, which can starve tissue of oxygen-carrying blood. Most strokes are the result of thrombosis.
Image by TheVisualMD
This browser does not support the video element.
Lipids, Heart Health and Baselining Your Health
Your blood "knows" what you eat, meaning that the cardiovascular system is a sensitive barometer of a person's health, including diet. What individuals eat is reflected in their blood chemistry and the health of their heart, arteries and vessels. Fats (also known as lipids), for example, are vital to health and wellbeing throughout our lives and yet they are mostly associated with obesity and cardiovascular disease. The problem is that not all fats (or cholesterol) are equal. They share basic chemical similarities, but they also have important differences, which, in turn, result in different roles and effects in the body. Tests that offer information on diet and heart health include total cholesterol, low-density lipoprotein (LDL or "bad" cholesterol), high-density lipoprotein (HDL or "good" cholesterol), and triglycerides.
Video by TheVisualMD
This browser does not support the video element.
What Is Atherosclerosis?
Voyage inside your body to see where cholesterol is made and how plaques form inside your arteries. Witness the inner workings of your own personal cholesterol factory: your liver. Dr. Mehmet Oz, Dr. Peter Fail, and other top experts talk about cholesterol-how it accumulates with other substances in your arteries as plaque, and what happens when plaques rupture. See exactly how tiny stents are inserted in blocked vessels, and view footage of actual bypass surgery. Discover how you can keep your arteries clear and flexible through lifestyle changes and medications.
Video by TheVisualMD
What cholesterol is and what cholesterol blood tests show
Video by Bupa Health UK/YouTube
Cholesterol Blood Test
Video by Baptist Health Physician Partners/YouTube
Cholesterol - what is it and how can you prevent high cholesterol?
Video by Healthchanneltv / cherishyourhealthtv/YouTube
Cholesterol Good and Bad
Video by The National Library of Medicine/YouTube
This browser does not support the video element.
What Is HDL and LDL Cholesterol?
This video explains the difference between HDL and LDL cholesterol. It also reveals what may occur when there are high levels of LDL in the body.LDL may stick to an artery's inner wall causing the build up of plaque, affecting blood flow. When an artery stiffens and constricts, aneurysm, heart attack, and stroke can occur.
Video by TheVisualMD
This browser does not support the video element.
Refined Carbohydrates and Atherosclerosis
Refined Carbohydrates and Atherosclerosis : In atherosclerosis, hard, fatty deposits called plaque build up inside your arteries. For decades it was thought that eating too many fatty foods, especially foods rich in cholesterol, was to blame for plaque accumulation.
Video by TheVisualMD
This browser does not support the video element.
Cardiovascular Inflammation
Heart disease is the number one killer of men and women in the U.S. The most common cause of heart attack, stroke, and cardiovascular death is atherosclerosis. Atherosclerosis is a chronic inflammatory response in the walls of arteries that leads to the hardening of arterial walls and the buildup of fatty deposits called plaques, or atheromas. Although the process of inflammation can be beneficial in other parts of the body, chronic inflammation within arterial walls is problematic as it seems to promote this underlying growth of plaque. The combination of arterial inflammation and the growth of plaque can lead to the rupture of the plaque, and result in a blood clot. Blood clots can lead to dangerous conditions such as heart attack or stroke.
Video by TheVisualMD
Total Cholesterol: Heart
TheVisualMD
Total Cholesterol: Heart and Liver
TheVisualMD
Total Cholesterol: Thrombus
TheVisualMD
2:46
Lipids, Heart Health and Baselining Your Health
TheVisualMD
3:10
What Is Atherosclerosis?
TheVisualMD
3:53
What cholesterol is and what cholesterol blood tests show
Bupa Health UK/YouTube
3:06
Cholesterol Blood Test
Baptist Health Physician Partners/YouTube
2:42
Cholesterol - what is it and how can you prevent high cholesterol?
Healthchanneltv / cherishyourhealthtv/YouTube
3:01
Cholesterol Good and Bad
The National Library of Medicine/YouTube
0:45
What Is HDL and LDL Cholesterol?
TheVisualMD
2:21
Refined Carbohydrates and Atherosclerosis
TheVisualMD
4:26
Cardiovascular Inflammation
TheVisualMD
Total Cholesterol/HDL Ratio
Total Cholesterol/HDL Ratio
Also called: TC/HDL ratio, Cholesterol ratio
The total cholesterol to HDL cholesterol ratio is a number that is helpful in predicting atherosclerosis, the process of fatty buildup in the walls of the arteries. The number is obtained by dividing total cholesterol by HDL (good) cholesterol.
Total Cholesterol/HDL Ratio
Also called: TC/HDL ratio, Cholesterol ratio
The total cholesterol to HDL cholesterol ratio is a number that is helpful in predicting atherosclerosis, the process of fatty buildup in the walls of the arteries. The number is obtained by dividing total cholesterol by HDL (good) cholesterol.
{"label":"Total Cholesterol\/HDL Ratio Reference Range","scale":"lin","step":0.1,"hideunits":false,"units":[{"printSymbol":"{ratio}","code":"{ratio}","name":"ratio"}],"items":[{"flag":"normal","label":{"short":"Normal","long":"Normal","orientation":"horizontal"},"values":{"min":0,"max":3.5},"text":"The optimum ratio is 3.5.","conditions":[]},{"flag":"normal","label":{"short":"Acceptable","long":"Acceptable","orientation":"horizontal"},"values":{"min":3.5,"max":5},"text":"Low total cholesterol and high HDL cholesterol lowers the ratio.","conditions":[]},{"flag":"abnormal","label":{"short":"High","long":"High","orientation":"horizontal"},"values":{"min":5,"max":10},"text":"The higher the ratio, the higher is the risk of developing heart disease.","conditions":[]}],"value":1.8}[{"normal":1},{"normal":0},{"abnormal":0}]
Use the slider below to see how your results affect your
health.
{ratio}
3.5
5
Your result is Normal.
The optimum ratio is 3.5.
Related conditions
Cholesterol is a type of fat (lipid) that is necessary for the maintenance of some body functions, like for instance the production of hormones. Cholesterol travels through the blood attached to certain proteins called lipoproteins.
There are two main types of lipoproteins, which are low-density lipoprotein cholesterol (LDL-C) also known as “bad cholesterol,” and high-density lipoprotein cholesterol (HDL-C) also known as “good cholesterol.”
LDL-C moves cholesterol into your arteries, hence increasing your risk of developing coronary heart disease (CHD); while HDL-C carries away excess cholesterol out of your arteries, therefore decreasing your risk for CHD.
To calculate your cholesterol ratio, divide your total cholesterol number by your HDL cholesterol number.
Total cholesterol, HDL-C, LDL-C, and triglycerides are usually part of a lipid profile test, which is used to monitor and screen for unhealthy levels of fats in the blood.
If you have borderline results or very imbalance lipid levels, your doctor may want to know what your total cholesterol to HDL ratio is, since it can provide more information about your overall CHD risk.
Every person with no risk factors for heart disease should get tested at least every five years as part of a routine check-up. When one or more risk factors for heart disease are associated, the test should be done more frequently.
Cardiovascular disease risk factors include:
Unbalanced diet
Being overweight or obese
Physical inactivity (sedentarism)
More than 50 years of age in women
More than 45 years of age in men
Cigarette smoking
Diabetes
High blood pressure
Family history of early heart disease
Already diagnosed heart disease
A small amount of blood will be drawn from a vein in your arm by using a needle.
In some cases,fasting for at least 9 to 12 hours is necessary. Follow your healthcare provider instructions.
Only the risks related to blood extraction, which are temporary discomfort, bruising, little bleeding, and risk of infection in the place where the needle was inserted.
Total cholesterol ranges in adults are:
Normal: less than 200 mg/dL.
Borderline high: from 200 to 239 mg/dL.
High: equal or greater than 240 mg/dL.
HDL levels in adults are:
Low: less than 40 mg/dL in men, and less than 50 mg/dL in women.
Acceptable: from 40 to 50 mg/dL in men, and from 50 to 59 mg/dL in women.
Optimal: equal or greater than 60 mg/dL.
An acceptable cholesterol ratio in adults is considered to be below 5 to 1 (5:1). While an optimal ratio is below 3.5 to 1 (3.5:1). The higher the ratio, the higher is the risk of developing CHD.
For example, if a person has a total cholesterol level of 230 mg/dL and an HDL level of 40 mg/dL (total cholesterol to HDL ratio: 230/40), the resulting ratio would be of 5.7 (or 5.7:1). This person does not have an acceptable ratio and therefore has an increased risk of developing CHD.
Lipid Panel with Total Cholesterol: HDL Ratio - Health Encyclopedia - University of Rochester Medical Center [accessed on Oct 08, 2018]
Normal reference ranges can vary depending on the laboratory and the method used for testing. You must use the range supplied by the laboratory that performed your test to evaluate whether your results are "within normal limits."
Additional Materials (9)
This browser does not support the video element.
What Is HDL and LDL Cholesterol?
This video explains the difference between HDL and LDL cholesterol. It also reveals what may occur when there are high levels of LDL in the body.LDL may stick to an artery's inner wall causing the build up of plaque, affecting blood flow. When an artery stiffens and constricts, aneurysm, heart attack, and stroke can occur.
Video by TheVisualMD
Triglycerides and HDL
Video by Joslin Diabetes Center/YouTube
The 5 Most Important Molecules in Your Body
Video by SciShow/YouTube
British Heart Foundation - Cholesterol and heart disease
Video by British Heart Foundation/YouTube
HDL: When Good Cholesterol Goes Bad
Video by UW Video/YouTube
Tri HDL
Video by ACAP Health/YouTube
High Density Lipoprotein: Cholesterol pathway
We get cholesterol from foods like red meat, dairy and eggs, but our livers produce most of our cholesterol in a multi-step process (drugs like statins interrupt this process). Cholesterol is carried in the bloodstream in specialized packages called lipoproteins.
Image by TheVisualMD
High Density Lipoprotein: Arterial Wall
It's estimated that there are nearly 100,000 miles of arteries in an adult body. The walls of these arteries are composed of fibroblasts, smooth muscle cells, elastica interna, and an endothelial cell layer.
Image by TheVisualMD
High Density Lipoprotein: Aerobic exercise
There are many factors that can potentially influence cholesterol levels. Exercise is an important one. Studies have shown that endurance athletes have higher HDL levels, and aerobic athletes in general, particularly lean ones, have lower LDL levels.
Image by TheVisualMD
0:45
What Is HDL and LDL Cholesterol?
TheVisualMD
3:25
Triglycerides and HDL
Joslin Diabetes Center/YouTube
7:55
The 5 Most Important Molecules in Your Body
SciShow/YouTube
6:23
British Heart Foundation - Cholesterol and heart disease
British Heart Foundation/YouTube
54:59
HDL: When Good Cholesterol Goes Bad
UW Video/YouTube
2:17
Tri HDL
ACAP Health/YouTube
High Density Lipoprotein: Cholesterol pathway
TheVisualMD
High Density Lipoprotein: Arterial Wall
TheVisualMD
High Density Lipoprotein: Aerobic exercise
TheVisualMD
Small-Dense LDL Test
Small-Dense LDL Test
Also called: sdLDL-C, Small-Dense LDL Cholesterol
Lipid profile screening is crucial for the prevention, evaluation and treatment of cardiovascular (CV) disease (CVD). Small dense low-density lipoprotein-cholesterol (sdLDL-C) is an emerging biomarker associated with CVD and several comorbidities.
Small-Dense LDL Test
Also called: sdLDL-C, Small-Dense LDL Cholesterol
Lipid profile screening is crucial for the prevention, evaluation and treatment of cardiovascular (CV) disease (CVD). Small dense low-density lipoprotein-cholesterol (sdLDL-C) is an emerging biomarker associated with CVD and several comorbidities.
{"label":"Small-Dense LDL Reference Range","scale":"lin","step":0.1,"hideunits":false,"units":[{"printSymbol":"mg\/dL","code":"mg\/dL","name":"milligram per deciliter"}],"items":[{"flag":"normal","label":{"short":"Normal","long":"Normal","orientation":"horizontal"},"values":{"min":0,"max":20},"text":"Normal results vary based on the laboratory and the method used.","conditions":[]},{"flag":"borderline","label":{"short":"Borderline","long":"Borderline","orientation":"horizontal"},"values":{"min":20,"max":30},"text":"","conditions":[]},{"flag":"abnormal","label":{"short":"High","long":"High","orientation":"horizontal"},"values":{"min":30,"max":100},"text":"A high percentage of small dense LDL particles is linked with coronary heart disease, through both an increase in the risk of developing it and the accelerated progression of existing disease. Having a large percentage of small dense LDL particles is usually accompanied by other disorders, including high triglyceride levels, reduced HDL-cholesterol levels, abdominal obesity, insulin resistance, and other metabolic disorders.","conditions":["Atherosclerosis","Coronary Heart Disease","Stroke","Peripheral Vascular Disease","Hypertension","Hyperlipidemia","Metabolic Syndrome"]}],"value":10}[{"normal":0},{"borderline":0},{"abnormal":0}]
Use the slider below to see how your results affect your
health.
mg/dL
20
30
Your result is Normal.
Normal results vary based on the laboratory and the method used.
Related conditions
Small dense LDL cholesterol is a direct measurement of a small dense LDL Lipoprotein. It has several subclasses of particles with different densities and sizes, including
large buoyant (lb)
intermediate
small dense (sd) LDLs
sdLDL has a greater atherogenic potential than other LDL subfractions and sdLDL cholesterol (sdLDL-C) proportion.
It also is a better marker for predicting cardiovascular disease than total LDL-C.
Spectracell Labs: Small-dense LDL [accessed on Sep 16, 2018]
Very Well Health: Reducing Small, Dense LDL Cholesterol [accessed on Sep 16, 2018]
Small Dense LDL Cholesterol (sdLDL-C) – Boston Heart [accessed on Sep 16, 2018]
sdLDL (36406) [accessed on Sep 16, 2018]
Small Dense LDL Cholesterol and Coronary Heart Disease: Results from the Framingham Offspring Study [accessed on Sep 16, 2018]
https://www.scgov.net/home/showdocument?id=30118 [accessed on Sep 16, 2018]
Normal reference ranges can vary depending on the laboratory and the method used for testing. You must use the range supplied by the laboratory that performed your test to evaluate whether your results are "within normal limits."
Additional Materials (19)
How Lipoproteins Affect Metabolism in Diabetes
Video by Mechanisms in Medicine/YouTube
Differences between small, dense LDL and large, buoyant LDL particles | Ronald Krauss
Video by FoundMyFitness Clips/YouTube
Cholesterol Metabolism, LDL, HDL and other Lipoproteins, Animation
Video by Alila Medical Media/YouTube
A Test in Focus: LDL Particle Concentration NMR, Plasma
Video by Mayo Clinic/YouTube
Why we Need "Bad" LDL Cholesterol | Dave Feldman Pt 2
Video by What I've Learned/YouTube
Preventive Cardiology: Cholesterol Management
Video by Mayo Clinic/YouTube
LDL Cholesterol: Particle Number & Size Matter for CHD
Video by Metagenics Institute/YouTube
Atherogenic Dyslipidemia. The lipid profile which is typical for patients with type 2 diabetes and the metabolic syndrome
The lipid profile which is typical for patients with type 2 diabetes and the metabolic syndrome
Image by Almoisten/Wikimedia
Nsequences of Atherogenic Diabetic Dyslipidemia (ADD)
nsequences of Atherogenic Diabetic Dyslipidemia (ADD)
Image by Hardikjoshi22887/Wikimedia
Lipoproteins
Lipid logistics: transport of triglycerides and cholesterol in organisms in form of lipoproteins as chylomicrons, VLDL, LDL, IDL, HDL.
Image by Peter Forster
Structure of LDL receptor family members
Members of the LDL receptor gene family contain five distinct modules present in characteristic numbers: LDL receptor type A (LA) repeats, necessary for ligand binding; EGF precursor homology domains, built up from EGF repeats and YWTD beta propellers; O-linked sugar domain; transmembrane domain; and a cytoplasmic tail harboring one or more NPxY motifs essential for binding of intracellular adapter proteins. Differentially spliced domains are depicted hatched.
Image by AntiSense/Wikimedia
Atherosclerotic artery on left, Normal Artery on the right
Atherosclerotic artery on left, Normal Artery on the right
Image by TheVisualMD
Micrograph of the distal right coronary artery with complex atherosclerosis and luminal narrowing
Low magnification micrograph of the distal right coronary artery with complex atherosclerosis and luminal narrowing. Masson's trichrome.
Arteries have three layers (tunica intima, tunica media and tunica adventitia). These can be seen on the micrograph:
Adventitia (outermost layer) = green fluffy material (collagen),
Media (middle (muscular) part) = red (smooth muscle actin),
Intima (inner part, in contact with the blood) = green (collagen) with some red (smooth muscle actin).
Features of atherosclerosis seen on the micrograph:
The tunica intima is severely thickened; it measures up to approximately 1/3 of a millimetre. Normally, it is one cell layer thick (approximately 10 micrometres).
There is fragmentation of the internal elastic lamina (a very thin black wavy layer) between the intima and media.
There is a partial duplication of the internal elastic lamina.
There is smooth muscle infiltration of the intima (from the media), i.e. red staining of the intima.
There is significant luminal narrowing. The section of the artery shown has only 25-35% of the cross-sectional area it once had; the artery's original lumen was approximately where the double layer of elastin is seen (the internal elastic lamina).
Features that may be seen in atherosclerosis but are not evident in the micrograph:
Calcifications.
Cholesterol crystals.
Image by Nephron
Lipids, Heart Health and Baselining Your Health
Your blood "knows" what you eat, meaning that the cardiovascular system is a sensitive barometer of a person's health, including diet. What individuals eat is reflected in their blood chemistry and the health of their heart, arteries and vessels. Fats (also known as lipids), for example, are vital to health and wellbeing throughout our lives and yet they are mostly associated with obesity and cardiovascular disease. The problem is that not all fats (or cholesterol) are equal. They share basic chemical similarities, but they also have important differences, which, in turn, result in different roles and effects in the body. Tests that offer information on diet and heart health include total cholesterol, low-density lipoprotein (LDL or "bad" cholesterol), high-density lipoprotein (HDL or "good" cholesterol), and triglycerides.
Image by TheVisualMD
What is Cholesterol?
Video by American Heart Association/YouTube
This browser does not support the video element.
Saturated Fat and Its Effects
Just like cholesterol can be divided into "good" and "bad" varieties, the rest of the fats family can be too. Dietary fats can be classified into two categories: saturated (the "bad" fats) and unsaturated (the "good" fats). Saturated fats are "bad" because they raise LDL ("bad" cholesterol) levels, which can cause plaque deposits to form on the walls of arteries, and increase the risk of diabetes, heart attacks and stroke. Among the most common dietary sources of saturated fats are fatty meats and dairy products.
Video by TheVisualMD
This browser does not support the video element.
Fiber and Lowering Cholesterol
Take steps towards better health exploring why a diet rich in soluble fiber is a great way to help lower "bad" LDL cholesterol. Soluble fiber (found in oats, apples, beans, barley) acts like a cholesterol sponge, soaking up "bad" LDL cholesterol in the small intestine and lowering the risk of cardiovascular disease. It can also help regulate blood sugar and reduce the risk of type 2 diabetes.
Video by TheVisualMD
Atherosclerosis | Circulatory System and Disease | NCLEX-RN | Khan Academy
Video by khanacademymedicine/YouTube
This browser does not support the video element.
Lipids, Heart Health and Baselining Your Health
Your blood "knows" what you eat, meaning that the cardiovascular system is a sensitive barometer of a person's health, including diet. What individuals eat is reflected in their blood chemistry and the health of their heart, arteries and vessels. Fats (also known as lipids), for example, are vital to health and wellbeing throughout our lives and yet they are mostly associated with obesity and cardiovascular disease. The problem is that not all fats (or cholesterol) are equal. They share basic chemical similarities, but they also have important differences, which, in turn, result in different roles and effects in the body. Tests that offer information on diet and heart health include total cholesterol, low-density lipoprotein (LDL or "bad" cholesterol), high-density lipoprotein (HDL or "good" cholesterol), and triglycerides.
Video by TheVisualMD
6:38
How Lipoproteins Affect Metabolism in Diabetes
Mechanisms in Medicine/YouTube
5:42
Differences between small, dense LDL and large, buoyant LDL particles | Ronald Krauss
FoundMyFitness Clips/YouTube
3:46
Cholesterol Metabolism, LDL, HDL and other Lipoproteins, Animation
Alila Medical Media/YouTube
4:22
A Test in Focus: LDL Particle Concentration NMR, Plasma
Mayo Clinic/YouTube
19:30
Why we Need "Bad" LDL Cholesterol | Dave Feldman Pt 2
What I've Learned/YouTube
3:58
Preventive Cardiology: Cholesterol Management
Mayo Clinic/YouTube
3:08
LDL Cholesterol: Particle Number & Size Matter for CHD
Metagenics Institute/YouTube
Atherogenic Dyslipidemia. The lipid profile which is typical for patients with type 2 diabetes and the metabolic syndrome
Almoisten/Wikimedia
Nsequences of Atherogenic Diabetic Dyslipidemia (ADD)
Hardikjoshi22887/Wikimedia
Lipoproteins
Peter Forster
Structure of LDL receptor family members
AntiSense/Wikimedia
Atherosclerotic artery on left, Normal Artery on the right
TheVisualMD
Micrograph of the distal right coronary artery with complex atherosclerosis and luminal narrowing
Nephron
Lipids, Heart Health and Baselining Your Health
TheVisualMD
2:54
What is Cholesterol?
American Heart Association/YouTube
1:03
Saturated Fat and Its Effects
TheVisualMD
1:07
Fiber and Lowering Cholesterol
TheVisualMD
13:45
Atherosclerosis | Circulatory System and Disease | NCLEX-RN | Khan Academy
khanacademymedicine/YouTube
2:46
Lipids, Heart Health and Baselining Your Health
TheVisualMD
High-Density Lipoprotein Test
High-Density Lipoprotein Test
Also called: HDL, HDL-C, HDL Cholesterol, High-Density Lipoprotein Cholesterol
HDL, or high-density lipoprotein, is the "good" cholesterol. It helps to remove bad cholesterol from your arteries, so a higher HDL level is better.
High-Density Lipoprotein Test
Also called: HDL, HDL-C, HDL Cholesterol, High-Density Lipoprotein Cholesterol
HDL, or high-density lipoprotein, is the "good" cholesterol. It helps to remove bad cholesterol from your arteries, so a higher HDL level is better.
{"label":"High-Density Lipoprotein Reference Range","scale":"lin","step":0.1,"hideunits":false,"units":[{"printSymbol":"mg\/dL","code":"mg\/dL","name":"milligram per deciliter"}],"items":[{"flag":"abnormal","label":{"short":"Low","long":"Low","orientation":"horizontal"},"values":{"min":1,"max":40},"text":"HDL levels less than 40 mg\/dL for men and less than 50 mg\/dL for women are associated with an increased risk of heart disease.","conditions":["Cardiovascular disease","Atherosclerosis"]},{"flag":"normal","label":{"short":"Desirable","long":"Desirable","orientation":"horizontal"},"values":{"min":40,"max":60},"text":"HDL levels between 40-50 mg\/dL for men, and 50-60 mg\/dl for women, are associated with average risk of heart disease. The higher HDL levels, the better.","conditions":[]},{"flag":"normal","label":{"short":"Optimal","long":"Optimal","orientation":"horizontal"},"values":{"min":60,"max":160},"text":"HDL levels of 60 mg\/dL (milligrams per deciliter) or higher are associated with a less-than-average risk of heart disease.","conditions":[]}],"value":50}[{"abnormal":0},{"normal":0},{"normal":1}]
Use the slider below to see how your results affect your
health.
mg/dL
40
60
Your result is Desirable.
HDL levels between 40-50 mg/dL for men, and 50-60 mg/dl for women, are associated with average risk of heart disease. The higher HDL levels, the better.
Related conditions
Cholesterol is a waxy, fat-like substance that's found in all the cells in your body. Your liver makes cholesterol, and it is also in some foods, such as meat and dairy products. Your body needs some cholesterol to work properly. But having too much cholesterol in your blood raises your risk of coronary artery disease.
HDL and LDL are two types of lipoproteins.They are a combination of fat (lipid) and protein. The lipids need to be attached to the proteins so they can move through the blood. HDL and LDL have different purposes:
HDL stands for high-density lipoproteins. It is sometimes called the "good" cholesterol because it carries cholesterol from other parts of your body back to your liver. Your liver then removes the cholesterol from your body.
LDL stands for low-density lipoproteins. It is sometimes called the "bad" cholesterol because a high LDL level leads to a buildup of cholesterol in your arteries.
A blood test can measure your cholesterol levels, including HDL. When and how often you should get this test depends on your age, risk factors, and family history. The general recommendations are:
For people who are age 19 or younger:
The first test should be between ages 9 to 11
Children should have the test again every 5 years
Some children may have this test starting at age 2 if there is a family history of high blood cholesterol, heart attack, or stroke
For people who are age 20 or older:
Younger adults should have the test every 5 years
Men ages 45 to 65 and women ages 55 to 65 should have it every 1 to 2 years
With HDL cholesterol, higher numbers are better, because a high HDL level can lower your risk for coronary artery disease and stroke. How high your HDL should be depends on your age and sex:
Group
Healthy HDL Level
Age 19 or younger
More than 45mg/dl
Men age 20 or older
More than 40mg/dl
Women age 20 or older
More than 50mg/dl
If your HDL level is too low, lifestyle changes may help. These changes may also help prevent other diseases, and make you feel better overall:
Eat a healthy diet. To raise your HDL level, you need to eat good fats instead of bad fats. This means limiting saturated fats, which include full-fat milk and cheese, high-fat meats like sausage and bacon, and foods made with butter, lard, and shortening. You should also avoid trans fats, which may be in some margarines, fried foods, and processed foods like baked goods. Instead, eat unsaturated fats, which are found in avocado, vegetable oils like olive oil, and nuts. Limit carbohydrates, especially sugar. Also try to eat more foods naturally high in fiber, such as oatmeal and beans.
Stay at a healthy weight. You can boost your HDL level by losing weight, especially if you have lots of fat around your waist.
Exercise. Getting regular exercise can raise your HDL level, as well as lower your LDL. You should try to do 30 minutes of moderate to vigorous aerobic exercise on most, if not all, days.
Avoid cigarettes. Smoking and exposure to secondhand smoke can lower your HDL level. If you are a smoker, ask your health care provider for help in finding the best way for you to quit. You should also try to avoid secondhand smoke.
Limit alcohol. Moderate alcohol may lower your HDL level, although more studies are needed to confirm that. What we do know is that too much alcohol can make you gain weight, and that lowers your HDL level.
Some cholesterol medicines, including certain statins, can raise your HDL level, in addition to lowering your LDL level. Health care providers don't usually prescribe medicines only to raise HDL. But if you have a low HDL and high LDL level, you might need medicine.
Taking certain medicines can lower HDL levels in some people. They include
Beta blockers, a type of blood pressure medicine
Anabolic steroids, including testosterone, a male hormone
Progestins, which are female hormones that are in some birth control pills and hormone replacement therapy
Benzodiazepines, sedatives that are often used for anxiety and insomnia
If you are taking one of these and you have a very low HDL level, ask your provider if you should continue to take them.
Diabetes can also lower your HDL level, so that gives you another reason to manage your diabetes.
HDL: The "Good" Cholesterol: MedlinePlus [accessed on Oct 08, 2018]
Cholesterol Levels: What You Need to Know: MedlinePlus [accessed on Oct 08, 2018]
High blood cholesterol levels: MedlinePlus Medical Encyclopedia [accessed on Oct 08, 2018]
Normal reference ranges can vary depending on the laboratory and the method used for testing. You must use the range supplied by the laboratory that performed your test to evaluate whether your results are "within normal limits."
Additional Materials (21)
HDL and LDL Molecules Subfractionization
The standard lipid profile, which measures the quantity of LDL and HDL cholesterol in the blood stream, has proven itself to be very useful in identifying many people who are risk for heart disease. But it doesn't catch everyone at risk. A more detailed lipid profile, called lipoprotein subfraction testing, divides the basic cholesterol groups into finer categories, which makes possible more accurate risk assessment. This interactive features all of the different tests involved in a lipid panel- HDL, LDL and VLDL, and the different subclasses for each.
Image by TheVisualMD
LDL particle
LDL (low-density lipoprotein or \"bad cholesterol\") along with HDL (high-density lipoprotein or \"good cholesterol\") are the two main types of cholesterol particles in the bloodstream. LDL is referred to as \"bad\" cholesterol because it forms deposits (plaque) in the lining of blood vessels. The size and density of the lipoprotein determines whether its cholesterol is classified as \"good: or \"bad\". Low-density lipoproteins (LDL) are larger, lighter, and fluffier; high-density lipoproteins (HDL) are small and dense. An LDL test is part of a lipid panel that measures total cholesterol, LDL, HDL, and triglycerides. Cholesterol tests do not diagnose heart disease; instead, they are used to estimate risk. And while cholesterol levels can vary widely among healthy individuals, the evidence suggests that low levels of LDL cholesterol decrease the risk of heart disease and stroke, while high levels of LDL increase that risk.
Image by TheVisualMD
Cholesterol, Healthy Heart
A heart-healthy lifestyle includes a diet based on the principles of balance, variety and moderation in the consumption of fats. Fats are essential nutrients and critical building blocks. The type of fat in a diet, however, turns out to be even more important than the total amount; there are \"good\" fats and \"bad\" dietary fats, just as there are \"good\" and \"bad\" types of cholesterol in our bloodstream. Other keys to cardiovascular health and wellbeing: get aerobic exercise, don't smoke, and drink alcohol only in moderation.
Image by TheVisualMD
Aerobic athletes in general, particularly lean ones, have lower LDL (or "bad" cholesterol) levels
There are many factors that can potentially influence cholesterol levels. Exercise may be an important one, though evidence is not definitive; studies have shown that endurance athletes have higher HDL (or \"good\" cholesterol) levels, and aerobic athletes in general, particularly lean ones, have lower LDL (or \"bad\" cholesterol) levels.
Image by TheVisualMD
Cross-Section View of HDL Lipoprotein
This image shows a cross-section of a globule of High Density-Lipoprotein (HDL). HDL has a large amount of protein, which makes it denser than other lipoproteins. The purple area shows protein content (33-57%), the off-white shell shows phospholipids (26-43%), and the yellow and red interior shows cholesterol (17-40%) and triglycerides (3-15%). HDL supplies two other lipoproteins-chylomicrons and VLDLs-with proteins that signal the liver to trap and extract their fat. HDL also sponges up excess cholesterol from blood vessel linings and carries it to the liver for removal. This reduces the risk of plaque build-up in the arteries and gives HDL its nickname \"good\" cholesterol.
Image by TheVisualMD
Cholesterol, Atherosclerotic Heart Disease
Atherosclerosis is a disease in which fatty deposits called plaque build up inside arteries; one of the components of plaque is LDL or \"bad\" cholesterol. Over time, plaque narrows the arteries, which limits the flow of oxygen-rich blood to the body; plaque in coronary arteries restricts blood supply to the heart. Plaque also makes the arterial walls stiff and less elastic, which is why a common term for artherosclerosis is \"hardening\" of the arteries. To try to clean up the mess, the endothelial cells that make up the inner lining send out chemical signals that summon inflammatory cells. These cells invade the area and engulf the fatty molecules, leaving behind the fatty streaks. If the levels of cholesterol don't drop, the buildup continues. The fats start to accumulate faster than the cleanup process can remove them and develop into noticeable deposits known as plaque. As the plaques grow, so do the problems. The bulging plaque reduces the diameter of the arteries, which decreases blood flow and increases blood pressure. As a defense, the arteries start shoring up, making more support cells to cope with the rising blood pressure. The arteries become less flexible; hence the description of the condition as hardening of the arteries.
Image by TheVisualMD
Cholesterol pathway
Cholesterol is essential for the maintenance of cell membranes, production of sex hormones, and absorption of key vitamins. We get cholesterol from the foods we eat (particularly red meat, dairy and eggs), but our livers produce most of it in a multi-step process (drugs like statins interrupt this process). Cholesterol is carried in the bloodstream in specialized packages called lipoproteins.
Image by TheVisualMD
Cholesterol Traveling Through Cell Membrane to HDL
This image shows the healthy membrane of an endothelial cell in a blood vessel wall. You can see the semi-permeable double layer of phospholipids that allows lipids to move across the membrane. The cholesterol molecules (yellow) maintain permeability by keeping the phospholipid tails from sticking together. Excess cholesterol molecules are passing through the phospholipid bilayer through passive, aqueous diffusion to a mature high-denisty lipoprotein (HDL) molecule. HDL is considered \"good\" cholesterol. The cell membrane benefits from this interaction with HDL and now has less cholesterol in the membrane. The HDL molecule carries the cholesterol away and back to the liver for recycling or degradation.
Image by TheVisualMD
High-Density Lipoprotein (HDL) Molecule
High-density lipoproteins, abbreviated HDL, are small and dense protein spheres that transport cholesterol, triglyceride, and other lipids through the bloodstream. Because the density of a protein bundle is associated with its ability to gather cholesterol from cells and transport it to the liver for eventual elimination, high-density lipoproteins are commonly referred to as the \"good\" cholesterol. A heart-healthy diet is rich in HDL sources. Wholesome foods that deliver Omega-3 fatty acids, antioxidants, and soluble fibers can raise HDL levels and provide numerous health benefits, including the warding off of life-threatening diseases.
Image by TheVisualMD
This browser does not support the video element.
What Is HDL and LDL Cholesterol?
This video explains the difference between HDL and LDL cholesterol. It also reveals what may occur when there are high levels of LDL in the body.LDL may stick to an artery's inner wall causing the build up of plaque, affecting blood flow. When an artery stiffens and constricts, aneurysm, heart attack, and stroke can occur.
Video by TheVisualMD
This browser does not support the video element.
Cardiovascular Inflammation
Heart disease is the number one killer of men and women in the U.S. The most common cause of heart attack, stroke, and cardiovascular death is atherosclerosis. Atherosclerosis is a chronic inflammatory response in the walls of arteries that leads to the hardening of arterial walls and the buildup of fatty deposits called plaques, or atheromas. Although the process of inflammation can be beneficial in other parts of the body, chronic inflammation within arterial walls is problematic as it seems to promote this underlying growth of plaque. The combination of arterial inflammation and the growth of plaque can lead to the rupture of the plaque, and result in a blood clot. Blood clots can lead to dangerous conditions such as heart attack or stroke.
Video by TheVisualMD
This browser does not support the video element.
Lipids, Heart Health and Baselining Your Health
Your blood "knows" what you eat, meaning that the cardiovascular system is a sensitive barometer of a person's health, including diet. What individuals eat is reflected in their blood chemistry and the health of their heart, arteries and vessels. Fats (also known as lipids), for example, are vital to health and wellbeing throughout our lives and yet they are mostly associated with obesity and cardiovascular disease. The problem is that not all fats (or cholesterol) are equal. They share basic chemical similarities, but they also have important differences, which, in turn, result in different roles and effects in the body. Tests that offer information on diet and heart health include total cholesterol, low-density lipoprotein (LDL or "bad" cholesterol), high-density lipoprotein (HDL or "good" cholesterol), and triglycerides.
Video by TheVisualMD
The 5 Most Important Molecules in Your Body
Video by SciShow/YouTube
Cholesterol Blood Test
Video by Baptist Health Physician Partners/YouTube
High Cholesterol Medical Animation (Hyperlipidemia)
Video by Silverback Video/YouTube
British Heart Foundation - Cholesterol and heart disease
Video by British Heart Foundation/YouTube
HDL: When Good Cholesterol Goes Bad
Video by UW Video/YouTube
Lipid Panel Interpretation
Video by FatIsNotYourFault/YouTube
Triglycerides and HDL
Video by Joslin Diabetes Center/YouTube
Tri HDL
Video by ACAP Health/YouTube
HDL Molecule
HDL Molecule
Image by TheVisualMD
HDL and LDL Molecules Subfractionization
TheVisualMD
LDL particle
TheVisualMD
Cholesterol, Healthy Heart
TheVisualMD
Aerobic athletes in general, particularly lean ones, have lower LDL (or "bad" cholesterol) levels
TheVisualMD
Cross-Section View of HDL Lipoprotein
TheVisualMD
Cholesterol, Atherosclerotic Heart Disease
TheVisualMD
Cholesterol pathway
TheVisualMD
Cholesterol Traveling Through Cell Membrane to HDL
TheVisualMD
High-Density Lipoprotein (HDL) Molecule
TheVisualMD
0:45
What Is HDL and LDL Cholesterol?
TheVisualMD
4:26
Cardiovascular Inflammation
TheVisualMD
2:46
Lipids, Heart Health and Baselining Your Health
TheVisualMD
7:55
The 5 Most Important Molecules in Your Body
SciShow/YouTube
3:06
Cholesterol Blood Test
Baptist Health Physician Partners/YouTube
1:19
High Cholesterol Medical Animation (Hyperlipidemia)
Silverback Video/YouTube
6:23
British Heart Foundation - Cholesterol and heart disease
British Heart Foundation/YouTube
54:59
HDL: When Good Cholesterol Goes Bad
UW Video/YouTube
1:16:38
Lipid Panel Interpretation
FatIsNotYourFault/YouTube
3:25
Triglycerides and HDL
Joslin Diabetes Center/YouTube
2:17
Tri HDL
ACAP Health/YouTube
HDL Molecule
TheVisualMD
Non-HDL Cholesterol Test
Non-HDL Cholesterol Test
Also called: Non-HDL-C, Non-High Density Lipoprotein Cholesterol
Under certain conditions, the risk of developing coronary heart disease (strokes, heart attack) cannot be properly assessed only by looking at the lipids test results. In these cases, the non-HDL cholesterol can be used to assess of how high a person's cardiovascular risk is.
Non-HDL Cholesterol Test
Also called: Non-HDL-C, Non-High Density Lipoprotein Cholesterol
Under certain conditions, the risk of developing coronary heart disease (strokes, heart attack) cannot be properly assessed only by looking at the lipids test results. In these cases, the non-HDL cholesterol can be used to assess of how high a person's cardiovascular risk is.
{"label":"Non-HDL Cholesterol Reference Range","scale":"lin","step":0.1,"hideunits":false,"units":[{"printSymbol":"mg\/dL","code":"mg\/dL","name":"milligram per deciliter"}],"items":[{"flag":"normal","label":{"short":"D","long":"Desirable","orientation":"horizontal"},"values":{"min":0,"max":130},"text":"You have optimal levels of non-HDL cholesterol; therefore, your cardiovascular risk is considered to be low. ","conditions":[]},{"flag":"normal","label":{"short":"Ad","long":"Above desirable","orientation":"horizontal"},"values":{"min":130,"max":159},"text":"You have normal levels of non-HDL cholesterol and your cardiovascular risk is considered to be low. However, you may benefit from changing some lifestyle habits to prevent your non-HDL-C levels from getting higher. ","conditions":[]},{"flag":"borderline","label":{"short":"Bh","long":"Borderline high","orientation":"horizontal"},"values":{"min":159,"max":189},"text":"Your non-HDL cholesterol is considered to be dangerously close to reaching suboptimal levels. Therefore, you need to start changing some lifestyle habits to prevent it from getting higher. Ask your healthcare provider what your test results mean in your specific case.","conditions":[]},{"flag":"abnormal","label":{"short":"H","long":"High","orientation":"horizontal"},"values":{"min":189,"max":219},"text":"Your non-HDL cholesterol is considered to be in suboptimal levels, which puts you at risk for developing coronary heart disease (stroke, heart attack). Therefore, you need to change some lifestyle habits to lower it. Ask your healthcare provider what your test results mean in your specific case.","conditions":["Coronary Heart Disease","Cardiovascular Risk","Heart Attack","Stroke"]},{"flag":"abnormal","label":{"short":"Vh","long":"Very high","orientation":"horizontal"},"values":{"min":219,"max":400},"text":"Your non-HDL cholesterol is considered to be at very suboptimal levels, which puts you at high risk for developing coronary heart disease (stroke, heart attack). Ask your healthcare provider what your test results mean in your specific case.","conditions":["Coronary Heart Disease","Cardiovascular Risk","Heart Attack","Stroke"]}],"value":65}[{"normal":1},{"normal":0},{"borderline":0},{"abnormal":0},{"abnormal":1}]
Use the slider below to see how your results affect your
health.
mg/dL
130
159
189
219
Your result is Desirable.
You have optimal levels of non-HDL cholesterol; therefore, your cardiovascular risk is considered to be low.
Related conditions
Cholesterol is a type of fat (lipid) that is necessary for the maintenance of some body functions, like for instance the production of hormones. Cholesterol travels through the blood attached to certain proteins called lipoproteins.
There are two main types of lipoproteins, which are low-density lipoprotein cholesterol (LDL-C) also known as “bad cholesterol,” and high-density lipoprotein cholesterol (HDL-C) also known as “good cholesterol.”
LDL-C moves cholesterol into your arteries, hence increasing your risk of developing coronary heart disease (CHD); while HDL-C carries away excess cholesterol out of your arteries, therefore decreasing your risk for CHD.
Nevertheless, there are other minor lipoproteins that are also involved in the development of CHD, such as very low-density lipoprotein (VLDL) and intermediate-density lipoprotein (IDL). This is the reason why the non-cholesterol levels reflect better the risk of developing CHD.
Non-HDL cholesterol is calculated by subtracting your levels of HDL cholesterol from your total cholesterol levels.
Total cholesterol, high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and triglycerides are usually part of a lipid profile test, which is used to monitor and screen for unhealthy levels of fats in the blood.
If you have borderline results or imbalanced lipid levels, your doctor may want to know what your non-HDL cholesterol is, since it can provide more information about your overall CHD risk.
Every person with no risk factors for heart disease should get tested at least every five years as part of a routine check-up. When one or more risk factors for heart disease are associated, the test should be done more frequently.
Risk factors for cardiovascular disease include:
Unbalanced diet
Physical inactivity (sedentarism)
Being overweight or obese
More than 50 years of age in women
More than 45 years of age in men
Cigarette smoking
Diabetes
High blood pressure
Family history of early heart disease
Previously diagnosed heart disease
A small amount of blood will be drawn from a vein in your arm by using a needle.
You will need to fast for at least 9 to 12 hours before the test. Usually, no other special preparations are needed.
Only the risks related to blood extraction, which are temporary discomfort, bruising, little bleeding, and risk of infection in the place where the needle was inserted.
Optimal non-HDL cholesterol levels are 130 mg/dL (3.37 mmol/L) for adults and 120 mg/dL (3.11 mmol/L) for children and teenagers.
Test results may vary depending on several factors, such as the method used by the laboratory, your age, gender, and medical history. Ask your healthcare provider what your test results mean in your specific case.
High levels of non-HDL-C are related to an increased risk of developing coronary heart disease (CHD), which includes heart attack and stroke.
This test is not diagnostic, but it’s rather used to evaluate a person’s risk to develop CVD.
Doc's Opinion: Non-HDL Cholesterol (Non-HDL-C) [accessed on Oct 03, 2018]
URMC / Encyclopedia / Lipid Panel with Non-HDL Cholesterol [accessed on Oct 03, 2018]
LPNF1 - Clinical: Lipid Panel, Non-Fasting, Serum [accessed on Oct 03, 2018]
Non-High Density Lipoprotein Cholesterol | Lab Tests Online [accessed on Oct 03, 2018]
344265: Non-HDL Cholesterol Profile | LabCorp [accessed on Oct 03, 2018]
Normal reference ranges can vary depending on the laboratory and the method used for testing. You must use the range supplied by the laboratory that performed your test to evaluate whether your results are "within normal limits."
Additional Materials (30)
Cholesterol Numbers - Mayo Clinic
Video by Mayo Clinic/YouTube
What is Cholesterol?
Video by American Heart Association/YouTube
How to Read and Understand Your Cholesterol Levels – Dr.Berg
Video by Dr. Eric Berg DC/YouTube
What Does My Non HDL Score Mean
Video by PreDiabetes Centers/YouTube
Recommended Cholesterol Levels
Video by AllHealthGo/YouTube
Supersize sperm from the past
Video by nature video/YouTube
A Return to Specific LDL-Cholesterol Goals
Video by Mayo Clinic/YouTube
At a Glance: What You Need To Know About High Blood Cholesterol
High blood cholesterol is one of the major risk factors for heart disease. In fact, the higher your blood
cholesterol, the greater your risk of developing heart
disease or having a heart attack. Heart disease is the
#1 killer of men and women in the United States.
Each year, more than a million Americans have a
heart attack, and about half a million people die of
heart disease.
Document by National Heart, Lung, and Blood Institute (NHLBI)
Your Guide to A Healthy Heart
Document by www.nhlbi.nih.gov
Nutrition Facts Label: Cholesterol
Cholesterol is a nutrient to get less of.
Document by Food and Drug Administration (FDA)
High Blood Cholesterol: What you need to know
Your blood cholesterol level has a lot to do with
your chances of getting heart disease.
Document by National Heart, Lung, and Blood Institute
On the Move to Better Heart Health for African Americans
Learn how to reduce your chances of having a heart attack or stroke by reducing your sodium intake. Includes healthy food choices, cooking ideas, information on shopping and reading food labels.
Document by www.nhlbi.nih.gov
Cholesterol Conversation Starters
Cholesterol can be a confusing health topic for a lot of people, but understanding and managing high blood cholesterol is an important step in taking control of heart health.
Document by Centers for Disease Control and Prevention (CDC)
Depression--Medicines To Help You
Do you feel depressed? Do not feel ashamed. Women are more likely than men to feel depressed. About 1 woman in 5 has depression in the U.S.
Document by FDA
What Is HDL and LDL Cholesterol?
This video explains the difference between HDL and LDL cholesterol. It also reveals what may occur when there are high levels of LDL in the body.LDL may stick to an artery's inner wall causing the build up of plaque, affecting blood flow. When an artery stiffens and constricts, aneurysm, heart attack, and stroke can occur.
Image by TheVisualMD
Cholesterol, Heart and Liver
Cholesterol is essential for the maintenance of cell membranes, production of sex hormones, and absorption of key vitamins. We get cholesterol from the foods we eat, but our livers produce most of it. There are two main types of cholesterol particles found in the bloodstream: HDL (high-density lipoprotein, or \"good\" cholesterol); and LDL (low-density lipoprotein, or \"bad\" cholesterol). LDL is referred to as bad cholesterol because it leads to the formation of plaque deposits that can clog arteries and increase the risk of heart disease.
Image by TheVisualMD
Bile Acid Sequestrant
Bile-acid sequestrants, also known as bile-acid resins, bind in the intestines with bile acids, which are produced by converting cholesterol. Bile acids are then eliminated in the stool, stimulating the liver to convert more cholesterol into bile acids, thereby lowering LDL-cholesterol levels. This is one mechanism of action that can be effective in lowering one's cholesterol and reducing one's risk of atherosclerosis and cardiovascular disease.
Image by TheVisualMD
Cholesterol Sources with Anatomy
Cholesterol is made by your own body. It is also found in food products derived from animals. Cholesterol is used to make bile acids in the liver, necessary for fat digestion. Cholesterol is constantly transported in the bloodstream between the liver and all the body's tissues. HDL-cholesterol helps clear excess cholesterol from your body. LDL-cholesterol is ingested by cells in need of cholesterol. LDL particles of the Pattern A type are larger and less dense and may be harmless. LDL particles of the Pattern B type, however, are smaller and more dense and can penetrate through the lining of an artery and into its interior. Oxidized LDL particles (oxLDL) can cause major damage.
Image by TheVisualMD
Cholesterol and Statins Infographic
Cholesterol and Statins Infographic
Image by FDA
Vessel Plaque Caused by Cholesterol
HDL, high density lipoprotein, is known as the body's \"good cholesterol\". It is a protein secreted by the liver that travels through the blood stream, picking up up excess cholesterol in the blood and transporting it to the liver for elimination from the body. It is favorable to have a high HDL count, as these are the molecules responsible for eliminating cholesterol from the blood, thereby preventing the fat from building up and causing complications such as atherosclerosis. LDL on the other hand, is the protein that transport cholesterol TO cells. Having a high LDL signifies that too much cholesterol is being delivered to cells, and the HDL may not be able to keep up with it. In this image, a flap of an artery in the body is cut open to reveal fatty deposits of cholesterol in the artery wall.
Image by TheVisualMD
Statin's effect on Cholesterol
Statin's effect on Cholesterol
Image by TheVisualMD
Fibrate Molecule
Fibrates lower triglyceride and modestly increase HDL levels by reducing the liver's VLDL production. VLDL is a type of \"bad cholesterol\", and stands for \"very low-density lipoprotein\". These molecules transport cholesterol to body cells and are what become dangerous to the body in excess. Fibrate plays a role in production of LDL that has a higher than usual affinity for LDL-receptors, gateways into cells from the blood stream. This means that LDL's are removed from the blood stream more frequently, thereby decreasing the risk of cholesterol buildup in the walls of arteries.
Image by TheVisualMD
Cholesterol Molecule
Cholesterol is a fatlike substance produced naturally by your body and is necessary for its health. Cholesterol is transported in your bloodstream throughout your system, bound to water-soluble particles called lipoproteins. LDL (low-density lipoproteins) transport cholesterol from the liver to body cells, while HDL (high-density lipoproteins) transport cholesterol from cells back to the liver. Cholesterol is used by cells to contribute to the structure of plasma membranes and is a precursor to many steroid hormones, bile acids, and vitamin D. It is important to have healthy levels of cholesterol, however, as the blood vessels through which the molecule travels around the body are suseptible to buildup of fat. This can lead to hardening of the arteries, or atherosclerosis.
Image by TheVisualMD
Cholesterol in the Bloodstream
Cholesterol is a fat-like substance that is transported through the bloodstream throughout the entire circulatory system. It is bound to water-soluble particles called liproproteins. Plaque buildup is characteristic of atherosclerosis, and can happen as a result of fatty materials such as cholesterol in the blood. As the cholesterol travels through the blood stream, it sticks to the artery walls and accumulates over time. It becomes hard and calcified, leading to detrimental results. Cholesterol builds up in the walls of the arteries around the body, often blocking blood supply to the vital areas. Seen in this image is a cut-away into an artery in the body where the hardened, fatty material has accumulated in the lumen, or opening. This plaque impedes on the necessary tube structure of the artery, preventing blood from flowing through. As a result, one can experience poor circulation or tissue death in the part of the body where that artery's destination lies.
Image by TheVisualMD
Anatomy of a Lipoprotein
Lipoproteins transport cholesterol, triglycerides, or other lipids through the bloodstream. Lipoproteins are protein spheres that consist of a core of triglycerides and cholesterol esters, surrounded by a shell made up of water-soluble phospholipids with embedded proteins and cholesterol. The lipid-laden core of the lipoprotein is insoluble in aqueous (water-based) blood, so the phospholipid-protein shell is necessary to allow the lipoprotein to float freely in the bloodstream.
Image by TheVisualMD
Anatomy of a Lipoprotein
Lipoproteins transport cholesterol, triglycerides, or other lipids through the bloodstream. Lipoproteins are protein spheres that consist of a core of triglycerides and cholesterol esters, surrounded by a shell made up of water-soluble phospholipids with embedded proteins and cholesterol. The lipid-laden core of the lipoprotein is insoluble in aqueous (water-based) blood, so the phospholipid-protein shell is necessary to allow the lipoprotein to float freely in the bloodstream.
Image by TheVisualMD
Anatomy of a Lipoprotein
Lipoproteins transport cholesterol, triglycerides, or other lipids through the bloodstream. Lipoproteins are protein spheres that consist of a core of triglycerides and cholesterol esters, surrounded by a shell made up of water-soluble phospholipids with embedded proteins and cholesterol. The lipid-laden core of the lipoprotein is insoluble in aqueous (water-based) blood, so the phospholipid-protein shell is necessary to allow the lipoprotein to float freely in the bloodstream.
Image by TheVisualMD
Anatomy of a Lipoprotein
Lipoproteins transport cholesterol, triglycerides, or other lipids through the bloodstream. Lipoproteins are protein spheres that consist of a core of triglycerides and cholesterol esters, surrounded by a shell made up of water-soluble phospholipids with embedded proteins and cholesterol. The lipid-laden core of the lipoprotein is insoluble in aqueous (water-based) blood, so the phospholipid-protein shell is necessary to allow the lipoprotein to float freely in the bloodstream.
Image by TheVisualMD
Cholesterol is Everywhere
The human body contains about 100-150 g of cholesterol, most of it incorporated into cell membranes. One of the other major uses of cholesterol is the production of bile acids (also known as bile salts) in the liver. Bile contains a number of ingredients, including water, cholesterol, and bile acids. Bile is necessary for the absorption of fats from fecal matter passing through the intestine.
Image by TheVisualMD
Controlling Cholesterol
Doctors generally recommend lifestyle changes as the first line of defense against cholesterol levels and atherosclerosis. In addition, one or more of the following drugs may be prescribed:
Image by TheVisualMD
2:16
Cholesterol Numbers - Mayo Clinic
Mayo Clinic/YouTube
2:54
What is Cholesterol?
American Heart Association/YouTube
8:15
How to Read and Understand Your Cholesterol Levels – Dr.Berg
Dr. Eric Berg DC/YouTube
0:51
What Does My Non HDL Score Mean
PreDiabetes Centers/YouTube
2:12
Recommended Cholesterol Levels
AllHealthGo/YouTube
1:58
Supersize sperm from the past
nature video/YouTube
10:36
A Return to Specific LDL-Cholesterol Goals
Mayo Clinic/YouTube
At a Glance: What You Need To Know About High Blood Cholesterol
National Heart, Lung, and Blood Institute (NHLBI)
Your Guide to A Healthy Heart
www.nhlbi.nih.gov
Nutrition Facts Label: Cholesterol
Food and Drug Administration (FDA)
High Blood Cholesterol: What you need to know
National Heart, Lung, and Blood Institute
On the Move to Better Heart Health for African Americans
www.nhlbi.nih.gov
Cholesterol Conversation Starters
Centers for Disease Control and Prevention (CDC)
Depression--Medicines To Help You
FDA
What Is HDL and LDL Cholesterol?
TheVisualMD
Cholesterol, Heart and Liver
TheVisualMD
Bile Acid Sequestrant
TheVisualMD
Cholesterol Sources with Anatomy
TheVisualMD
Cholesterol and Statins Infographic
FDA
Vessel Plaque Caused by Cholesterol
TheVisualMD
Statin's effect on Cholesterol
TheVisualMD
Fibrate Molecule
TheVisualMD
Cholesterol Molecule
TheVisualMD
Cholesterol in the Bloodstream
TheVisualMD
Anatomy of a Lipoprotein
TheVisualMD
Anatomy of a Lipoprotein
TheVisualMD
Anatomy of a Lipoprotein
TheVisualMD
Anatomy of a Lipoprotein
TheVisualMD
Cholesterol is Everywhere
TheVisualMD
Controlling Cholesterol
TheVisualMD
Low Density Lipoprotein Test
Low Density Lipoprotein Test
Also called: LDL, LDL-C, LDL Cholesterol, Low-Density Lipoprotein Cholesterol
LDL, or low-density lipoprotein, is the "bad" cholesterol. A high LDL level can lead to a buildup of cholesterol in your arteries. Too much LDL is linked to heart disease and stroke.
Low Density Lipoprotein Test
Also called: LDL, LDL-C, LDL Cholesterol, Low-Density Lipoprotein Cholesterol
LDL, or low-density lipoprotein, is the "bad" cholesterol. A high LDL level can lead to a buildup of cholesterol in your arteries. Too much LDL is linked to heart disease and stroke.
{"label":"Low Density Lipoprotein Reference Range","scale":"lin","step":0.1,"hideunits":false,"units":[{"printSymbol":"mg\/dL","code":"mg\/dL","name":"milligram per deciliter"}],"items":[{"flag":"normal","label":{"short":"O","long":"Optimal","orientation":"horizontal"},"values":{"min":20,"max":100},"text":"The optimal level of LDL has changed over time and depends on the number of risk factors you have for heart disease and stroke. Generally, you want your LDL to be low. It's possible to have extremely low levels of LDL, but this is rare.","conditions":[]},{"flag":"normal","label":{"short":"No","long":"Near optimal","orientation":"horizontal"},"values":{"min":100,"max":130},"text":"The optimal level of LDL has changed over time and depends on the number of risk factors you have for heart disease and stroke. You want your LDL to be low. Too much LDL is linked to heart disease and stroke.","conditions":[]},{"flag":"borderline","label":{"short":"Bh","long":"Borderline high","orientation":"horizontal"},"values":{"min":130,"max":160},"text":"Borderline LDL represents the at-risk stage of developing high LDL. High LDL contributes to cardiovascular disease, which can cause a heart attack or stroke.","conditions":["Dyslipidemia"]},{"flag":"abnormal","label":{"short":"H","long":"High","orientation":"horizontal"},"values":{"min":160,"max":190},"text":"If you have a high LDL level, this means that you have too much LDL cholesterol in your blood. High LDL contributes to cardiovascular disease, which can cause a heart attack or stroke.","conditions":["Angina","Atherosclerosis","Dyslipidemia","Familial hypercholesterolemia","Heart attack","Metabolic syndrome","Peripheral artery disease","Stroke"]},{"flag":"abnormal","label":{"short":"Vh","long":"Very high","orientation":"horizontal"},"values":{"min":190,"max":300},"text":"If you have a high LDL level, this means that you have too much LDL cholesterol in your blood. High LDL contributes to cardiovascular disease, which can cause a heart attack or stroke.","conditions":["Angina","Atherosclerosis","Dyslipidemia","Familial hypercholesterolemia","Heart attack","Metabolic syndrome","Peripheral artery disease","Stroke"]}],"value":60}[{"normal":1},{"normal":0},{"borderline":0},{"abnormal":0},{"abnormal":1}]
Use the slider below to see how your results affect your
health.
mg/dL
100
130
160
190
Your result is Optimal.
The optimal level of LDL has changed over time and depends on the number of risk factors you have for heart disease and stroke. Generally, you want your LDL to be low. It's possible to have extremely low levels of LDL, but this is rare.
Related conditions
Cholesterol is a waxy, fat-like substance that's found in all the cells in your body. Your liver makes cholesterol, and it is also in some foods, such as meat and dairy products. Your body needs some cholesterol to work properly. But having too much cholesterol in your blood raises your risk of coronary artery disease.
LDL and HDL are two types of lipoproteins. They are a combination of fat (lipid) and protein. The lipids need to be attached to the proteins so they can move through the blood. LDL and HDL have different purposes:
LDL stands for low-density lipoproteins. It is sometimes called the "bad" cholesterol because a high LDL level leads to a buildup of cholesterol in your arteries.
HDL stands for high-density lipoproteins. It is sometimes called the "good" cholesterol because it carries cholesterol from other parts of your body back to your liver. Your liver then removes the cholesterol from your body.
If you have a high LDL level, this means that you have too much LDL cholesterol in your blood. This extra LDL, along with other substances, forms plaque. The plaque builds up in your arteries; this is a condition called atherosclerosis.
Coronary artery disease happens when the plaque buildup is in the arteries of your heart. It causes the arteries to become hardened and narrowed, which slows down or blocks the blood flow to your heart. Since your blood carries oxygen to your heart, this means that your heart may not be able to get enough oxygen. This can cause angina (chest pain), or if the blood flow is completely blocked, a heart attack.
A blood test can measure your cholesterol levels, including LDL. When and how often you should get this test depends on your age, risk factors, and family history. The general recommendations are:
For people who are age 19 or younger:
The first test should be between ages 9 to 11
Children should have the test again every 5 years
Some children may have this test starting at age 2 if there is a family history of high blood cholesterol, heart attack, or stroke
For people who are age 20 or older:
Younger adults should have the test every 5 years
Men ages 45 to 65 and women ages 55 to 65 should have it every 1 to 2 years
Things that can affect your LDL level include
Diet. Saturated fat and cholesterol in the food you eat make your blood cholesterol level rise
Weight. Being overweight tends to raise your LDL level, lower your HDL level, and increase your total cholesterol level
Physical Activity. A lack of physical activity can lead to weight gain, which can raise your LDL level
Smoking. Cigarette smoking lowers your HDL cholesterol. Since HDL helps to remove LDL from your arteries, if you have less HDL, that can contribute to you having a higher LDL level.
Age and Gender. As women and men get older, their cholesterol levels rise. Before the age of menopause, women have lower total cholesterol levels than men of the same age. After the age of menopause, women's LDL levels tend to rise.
Genetics. Your genes partly determine how much cholesterol your body makes. High cholesterol can run in families. For example, familial hypercholesterolemia (FH) is an inherited form of high blood cholesterol.
Medicines. Certain medicines, including steroids, some blood pressure medicines, and HIV/AIDS medicines, can raise your LDL level.
Other medical conditions. Diseases such as chronic kidney disease, diabetes, and HIV/AIDS can cause a higher LDL level.
Race. Certain races may have an increased risk of high blood cholesterol. For example, African Americans typically have higher HDL and LDL cholesterol levels than whites.
With LDL cholesterol, lower numbers are better, because a high LDL level can raise your risk for coronary artery disease and related problems:
LDL (Bad) Cholesterol Level
LDL Cholesterol Category
Less than 100mg/dL
Optimal
100-129mg/dL
Near optimal/above optimal
130-159 mg/dL
Borderline high
160-189 mg/dL
High
190 mg/dL and above
Very High
There are two main ways to lower your LDL cholesterol:
Therapeutic lifestyle changes (TLC). TLC includes three parts:
Heart-healthy eating. A heart-healthy eating plan limits the amount of saturated and trans fats that you eat. Examples of eating plans that can lower your cholesterol include the Therapeutic Lifestyle Changes diet and the DASH eating plan.
Weight Management. If you are overweight, losing weight can help lower your LDL cholesterol.
Physical Activity. Everyone should get regular physical activity (30 minutes on most, if not all, days).
Drug Treatment. If lifestyle changes alone do not lower your cholesterol enough, you may also need to take medicines. There are several types of cholesterol-lowering drugs available, including statins. The medicines work in different ways and can have different side effects. Talk to your health care provider about which one is right for you. While you are taking medicines to lower your cholesterol, you still should continue with the lifestyle changes.
Some people with familial hypercholesterolemia (FH) may receive a treatment called lipoprotein apheresis. This treatment uses a filtering machine to remove LDL cholesterol from the blood. Then the machine returns the rest of the blood back to the person.
https://medlineplus.gov/ldlthebadcholesterol.html [accessed on Mar 01, 2019]
https://medlineplus.gov/ency/patientinstructions/000386.htm [accessed on Mar 01, 2019]
https://labtestsonline.org/tests/ldl-cholesterol [accessed on Mar 01, 2019]
https://my.clevelandclinic.org/health/articles/11920-cholesterol-numbers-what-do-they-mean [accessed on Mar 01, 2019]
Normal reference ranges can vary depending on the laboratory and the method used for testing. You must use the range supplied by the laboratory that performed your test to evaluate whether your results are "within normal limits."
Additional Materials (19)
Lipids and Lipoproteins
Lipids and Lipoproteins
Image by TheVisualMD
Lipid Absorption
Lipid Absorption
Image by OpenStax College
Cholesterol
Cholesterol is a soft, waxy, fatty substance that's found naturally in every cell in your body. It's categorized as a lipid-that is, a fat, oil, or wax that won't dissolve in water. Cholesterol is necessary for your body's health because it helps to make cell membranes, digest fats, and produce vitamin D and various steroid hormones. Your bloodstream transports cholesterol throughout your body bound to water-soluble particles called lipoproteins.
Image by TheVisualMD
Lipids & Fats
Image by TheVisualMD
Lipids & Fats
Lipids & Fats
Image by TheVisualMD
Anatomy of a Lipoprotein
Lipoproteins transport cholesterol, triglycerides, or other lipids through the bloodstream. Lipoproteins are protein spheres that consist of a core of triglycerides and cholesterol esters, surrounded by a shell made up of water-soluble phospholipids with embedded proteins and cholesterol. The lipid-laden core of the lipoprotein is insoluble in aqueous (water-based) blood, so the phospholipid-protein shell is necessary to allow the lipoprotein to float freely in the bloodstream.
Image by TheVisualMD
Anatomy of a Lipoprotein
Lipoproteins transport cholesterol, triglycerides, or other lipids through the bloodstream. Lipoproteins are protein spheres that consist of a core of triglycerides and cholesterol esters, surrounded by a shell made up of water-soluble phospholipids with embedded proteins and cholesterol. The lipid-laden core of the lipoprotein is insoluble in aqueous (water-based) blood, so the phospholipid-protein shell is necessary to allow the lipoprotein to float freely in the bloodstream.
Image by TheVisualMD
Dr. Tara Dall discusses LDL, LDL Cholesterol (LDL-C) & LDL Particles (LDL-P)
Video by AdvLip/YouTube
What Is HDL and LDL Cholesterol?
This video explains the difference between HDL and LDL cholesterol. It also reveals what may occur when there are high levels of LDL in the body.LDL may stick to an artery's inner wall causing the build up of plaque, affecting blood flow. When an artery stiffens and constricts, aneurysm, heart attack, and stroke can occur.
Image by TheVisualMD
The New Marker for Heart Disease that is BETTER than LDL Cholesterol
Video by Dr. Adrian Chavez/YouTube
% Small Dense LDL Cholesterol
The predominance of small, dense low-density lipoprotein (LDL) is now recognized as a serious cardiovascular risk factor by the National Cholesterol Education Program Adult Treatment Panel. Research showed that the predominance of small, dense LDL is associated with an increased risk of coronary artery disease (CAD).
Image by TheVisualMD
This browser does not support the video element.
What Is HDL and LDL Cholesterol?
This video explains the difference between HDL and LDL cholesterol. It also reveals what may occur when there are high levels of LDL in the body.LDL may stick to an artery's inner wall causing the build up of plaque, affecting blood flow. When an artery stiffens and constricts, aneurysm, heart attack, and stroke can occur.
Video by TheVisualMD
HDL and LDL Cholesterol Sub-fraction, Heart Disease
The standard lipid profile, which measures the quantity of LDL (\"bad\") and HDL (\"good\") cholesterol in the bloodstream, has proven itself to be useful in identifying many people who are at risk for heart disease. But it doesn't catch everyone at risk. A more detailed lipid profile, called lipoprotein sub-fraction testing, categorizes cholesterol particles according to their size and density. Such testing is more sensitive and is especially useful for people who have a strong family history of heart disease. Heart attack (myocardial infarction) is a condition when blood flow to the heart is reduced or blocked. Heart cells die when the blood supply is cut off; the longer the blood supply is cut off, the greater the area of heart damage.
Image by TheVisualMD
Low Density Lipoprotein: Arterial Wall
It's estimated that there are nearly 100,000 miles of arteries in an adult body. The walls of these arteries are composed of fibroblasts, smooth muscle cells, elastica interna, and an endothelial cell layer.
Image by TheVisualMD
Constantly High Levels Of Insulin Causes Weight Gain
Tap each number for a closer look at the process of fat storage and usage.
Interactive by TheVisualMD
Low Density Lipoprotein: Clogged Arteries (Atherosclerosis) / Plaque in Coronary Artery, close up
Plaque in Coronary Artery / Leading to a Heart Attack
1) Plaque in Coronary Artery - In this image, a tiny coronary artery has been cross-sectioned to reveal a stenosis, or narrowing, caused by fatty deposits in the blood stream. Plaque in a coronary artery may break apart, and the resulting release of platelet adhesion-enhancing substances encourages clots to form on the plaque surface. The clot may then block the flow of blood through the already narrowed artery. Having this condition present in the coronary arteries is particularly dangerous because these are the arteries that wrap around the surface of the heart and supply the organ itself with oxygen and nutrients needed to pump blood to the entire body.
2) Leading to a Heart Attack - In this image, a tiny coronary artery has been cross-sectioned to reveal a stenosis, or narrowing, caused by fatty deposits in the blood stream. It is evident that this stenosis has advanced such that tissue necrosis, or death, has occurred in the area upstream from the blockage. Plaque in a coronary artery may break apart, and the resulting release of platelet adhesion-enhancing substances encourages clots to form on the plaque surface. The clot may then block the flow of blood through the already narrowed artery. Having this condition present in the coronary arteries is particularly dangerous because these are the arteries that wrap around the surface of the heart and supply the organ itself with oxygen and nutrients needed to pump blood to the entire body. This heart has been severely injured and the individual is at a high risk for heart attack.
Lp-PLA2 (or lipoprotein-associated phospholipase A2) is an enzyme produced by specialized immune cells called macrophages that engulf and destroy pathogens, foreign particles, aging cells and biological debris. Most of the Lp-PLA2 in the body is bound to LDL (or `bad` cholesterol) and the enzyme, like LDL, is linked to inflammation and the formation of plaques on blood vessel walls. Because Lp-PLA2 is very specifically linked to inflammation of blood vessels rather than inflammation that is systemic (throughout the body), it is a particularly good biomarker for vessel health.
Image by TheVisualMD
Oleic Acid Molecule
Oleic acid is a monounsaturated Omega-9 fatty acid found in animal and vegetable fats. Monounsaturated fats have one double bond between carbon atoms in the chain and polyunsaturated fats have more than one double bond. These fats lower the risk of heart disease by reducing levels of low-density lipoprotein (LDL, or "bad" cholesterol) in the blood. In this model, carbon atoms are dark gray, hydrogen atoms are white, and oxygen atoms are red. Interactive also available on white background.
Image by TheVisualMD
Lipoprotein(a) Molecule
The test for Lipoprotein(a) is used to help assess an individual's risk of developing cardiovascular disease. Unlike other risk factors for heart disease, however, Lp(a) levels are largely genetically determined and remain fairly stable over a person's life; they are also relatively resistant to treatment by either lifestyle changes or drugs. So why test for it? Because it is additional risk factor that can flag patients and their doctors to take an aggressive approach towards other, more treatable risk factors.
Image by TheVisualMD
Lipids and Lipoproteins
TheVisualMD
Lipid Absorption
OpenStax College
Cholesterol
TheVisualMD
Lipids & Fats
TheVisualMD
Lipids & Fats
TheVisualMD
Anatomy of a Lipoprotein
TheVisualMD
Anatomy of a Lipoprotein
TheVisualMD
8:37
Dr. Tara Dall discusses LDL, LDL Cholesterol (LDL-C) & LDL Particles (LDL-P)
AdvLip/YouTube
What Is HDL and LDL Cholesterol?
TheVisualMD
5:19
The New Marker for Heart Disease that is BETTER than LDL Cholesterol
Dr. Adrian Chavez/YouTube
% Small Dense LDL Cholesterol
TheVisualMD
0:45
What Is HDL and LDL Cholesterol?
TheVisualMD
HDL and LDL Cholesterol Sub-fraction, Heart Disease
TheVisualMD
Low Density Lipoprotein: Arterial Wall
TheVisualMD
Constantly High Levels Of Insulin Causes Weight Gain
TheVisualMD
Plaque in Coronary Artery / Leading to a Heart Attack
Also called: Apo B/Apo A-I, Apolipoprotein B/A1 Ratio, Apolipoprotein B/Apolipoprotein A-I ratio, ApoB:ApoA-1 ratio
Apolipoproteins (Apo) are proteins that provide structure and serves to carry lipids (fat) molecules through the bloodstream. Apo A-I mirrors the levels of HDL cholesterol (good cholesterol); while Apo B mirrors the levels of LDL cholesterol (Bad cholesterol). This test is useful to help determine your risk of developing atherosclerosis and coronary...
Apo B/A-I Ratio
Also called: Apo B/Apo A-I, Apolipoprotein B/A1 Ratio, Apolipoprotein B/Apolipoprotein A-I ratio, ApoB:ApoA-1 ratio
Apolipoproteins (Apo) are proteins that provide structure and serves to carry lipids (fat) molecules through the bloodstream. Apo A-I mirrors the levels of HDL cholesterol (good cholesterol); while Apo B mirrors the levels of LDL cholesterol (Bad cholesterol). This test is useful to help determine your risk of developing atherosclerosis and coronary...
{"label":"Apo B\/A-I Ratio Reference Range","scale":"lin","step":0.1,"hideunits":false,"units":[{"printSymbol":"{ratio}","code":"{ratio}","name":"ratio"}],"items":[{"flag":"normal","label":{"short":"Average Risk","long":"Average Risk","orientation":"horizontal"},"values":{"min":0,"max":0.6},"text":"You have the same risk of developing cardiovascular disease than everyone else's. ","conditions":[]},{"flag":"abnormal","label":{"short":"2x Average Risk","long":"2x Average Risk","orientation":"horizontal"},"values":{"min":0.6,"max":0.9},"text":"Your risk of developing cardiovascular disease is two times higher than it is for the average person. ","conditions":["Atherosclerosis","Cardiovascular Disease","Coronary Heart Disease","Metabolic Syndrome","Stroke","Myocardial Infarction","Heart Attack","",""]},{"flag":"abnormal","label":{"short":"3x Average Risk","long":"3x Average Risk","orientation":"horizontal"},"values":{"min":0.9,"max":2},"text":"Your risk of developing cardiovascular disease is three times higher than it is for the average person.","conditions":["Atherosclerosis","Cardiovascular Disease","Coronary Heart Disease","Metabolic Syndrome","Stroke","Myocardial Infarction","Heart Attack",""]}],"value":0.3}[{"normal":0},{"abnormal":0},{"abnormal":1}]
Use the slider below to see how your results affect your
health.
{ratio}
0.6
0.9
Your result is Average Risk.
You have the same risk of developing cardiovascular disease than everyone else's.
Related conditions
Apolipoproteins are certain types of proteins that play specific roles in the metabolism and transportation of lipids (fat) through the bloodstream.
Apolipoprotein A1 (Apo-A1) is a protein that is an important component of HDL cholesterol (HDL-C). While apolipoprotein B (Apo-B) is a protein that is an important component of LDL cholesterol (LDL-C) and non-HDL cholesterol.
LDL-C (known as “bad” cholesterol”) moves cholesterol into your arteries, hence increasing your risk of developing atherosclerosis (build-up of fat inside your blood vessels). While, HDL-C (known as “good” cholesterol”) carries away excess cholesterol out of your arteries, therefore decreasing your risk of atherosclerosis.
An apolipoprotein B/apolipoprotein A-I ratio test measures and correlates both these proteins in a sample of your blood.
Because apolipoprotein B levels tend to mirror LDL-C levels, and apolipoprotein A-I tend to mirror HDL-C levels, this test serves to indicate the cholesterol balance between particles that could potentially lead to atherosclerosis from those that could prevent it.
Therefore, an apolipoprotein B/apolipoprotein A-I ratio test is mostly used to help determine your risk of developing atherosclerosis and coronary heart disease (CHD).
Your doctor may want to order this test in the following situations:
When the level of cholesterol or triglycerides in your blood is high
In case of existing family history of atherosclerosis/heart diseases
To assess your risk of developing heart disease
To monitor the effectiveness of lipid treatment
A needle will be used to take a blood sample from a vein in your arm.
No fasting or other preparations are needed. However, you should inform your healthcare practitioner if you are taking any over-the-counter or prescription drugs.
You may feel discomfort when the needle is inserted and extracted but otherwise is a quick procedure. You may also experience bruising and a little bleeding, as well as mild soreness for a short amount of time after the blood extraction.
Males
Average Risk: <0.7
2x Average Risk: 0.7-0.9
3x Average Risk: >0.9
Females
Average Risk: <0.6
2x Average Risk: 0.6-0.9
3x Average Risk: >0.9
An elevated Apolipoprotein B/Apolipoprotein A-I ratio is associated with an increased risk of atherosclerosis and coronary heart disease (strokes, heart attack).
This ratio may correlate better with an increased risk of cardiovascular disease than other tests, namely total cholesterol, and LDL:HDL ratio.
There is another test called Apolipoprotein A-I/Apolipoprotein B ratio, which measures the same apolipoproteins in the blood, but inversely (Apo A-I to Apo B). Therefore, its results are reversed, meaning that the higher the ratio, the lesser is the person’s risk of developing coronary heart disease.
APABR - Clinical: Apolipoprotein A1 and B, Plasma [accessed on Oct 10, 2018]
Apo B/Apo A-I Ratio is Statistically A Better Predictor of Cardiovascular Disease (CVD) than Conventional Lipid Profile: A Study from Kathmandu Valley, Nepal [accessed on Oct 10, 2018]
The value of Apolipoprotein B/Apolipoprotein A1 ratio for metabolic syndrome diagnosis in a Chinese population: a cross-sectional study | Lipids in Health and Disease | Full Text [accessed on Oct 10, 2018]
Medscape: Medscape Access [accessed on Oct 10, 2018]
216010: Apolipoprotein Assessment | LabCorp [accessed on Oct 10, 2018]
Apolipoprotein A-I/B Ratios May Be Useful in Coronary Heart Disease Risk Assessment | Laboratory Medicine | Oxford Academic [accessed on Oct 10, 2018]
Normal reference ranges can vary depending on the laboratory and the method used for testing. You must use the range supplied by the laboratory that performed your test to evaluate whether your results are "within normal limits."
Additional Materials (9)
Apo B Animation - English
Video by FHJourneys/YouTube
Lipids and Lipoproteins
Lipids and Lipoproteins
Image by TheVisualMD
Lipids & Fats
Lipids & Fats
Image by TheVisualMD
Cross-Section View of LDL Lipoprotein
This image shows a cross-section of a globule of Low Density-Lipoprotein (LDL). LDL are large and lightweight protein spheres that transport cholesterol, triglyceride, and other lipid molecules through the bloodstream.The purple area shows protein content (20-22%), the off-white shell shows phospholipids (45-58%), and the yellow and red interior shows cholesterol (45-58%) and triglycerides (12-15%). LDL is considered \"bad cholesterol\" because its low-density protein bundles float in the bloodstream and deposit excess cholesterol in the walls of blood vessels, therefore contributing to the build-up of arterial plaque (atherosclerosis).
Image by TheVisualMD
High-Density Lipoprotein (HDL) Molecule
High-density lipoproteins, abbreviated HDL, are small and dense protein spheres that transport cholesterol, triglyceride, and other lipids through the bloodstream. Because the density of a protein bundle is associated with its ability to gather cholesterol from cells and transport it to the liver for eventual elimination, high-density lipoproteins are commonly referred to as the \"good\" cholesterol. A heart-healthy diet is rich in HDL sources. Wholesome foods that deliver Omega-3 fatty acids, antioxidants, and soluble fibers can raise HDL levels and provide numerous health benefits, including the warding off of life-threatening diseases.
Image by TheVisualMD
Low-Density Lipoprotein (LDL) Molecule
Low-density lipoproteins, abbreviated LDL, are large and lightweight protein spheres that transport cholesterol, triglyceride, and other lipid molecules through the bloodstream. LDL carries cholesterol in the blood. LDL is considered \"bad cholesterol\" because its low-density protein bundles float in the bloodstream and deposit excess cholesterol in the walls of blood vessels, therefore contributing to the build-up of arterial plaque (atherosclerosis). Controlling LDL levels by means of a healthy diet is key to lowering and preventing the risk of heart disease. Even if you have high LDL results in a lipid test, they can be reduced by smart dietary adjustments. Foods that are low in saturated fat and high in soluble fiber have been found to be helpful in lowering LDL. Weight loss and diet can account for up to a 20% reduction in LDL levels.
Image by TheVisualMD
Hyperlipidemia
A 4-ml sample of hyperlipidemic blood with lipids separated into the top fraction (Sample is in an EDTA collection tube.)
Image by Mark-shea at the wikipedia project
Lipoproteins
Lipid logistics: transport of triglycerides and cholesterol in organisms in form of lipoproteins as chylomicrons, VLDL, LDL, IDL, HDL.
Image by Peter Forster
Human Heart Displaying Aorta and Coronary Artery
Apolipoprotein B
Heart Cross Section Revealing Valve and Nerve
1
2
3
Human Heart
1) Human Heart Displaying Aorta and Coronary Artery - 3D visualization based on scanned human data of an anterior view of the heart.
2) Coronary Arteries - Your heart is a hollow, muscular organ whose only job is to pump blood throughout your body. Because every cell in your body must have a never-ending supply of oxygenated blood, your heart never sleeps. It beats about 100,000 times a day, pumping 6 qts of blood through the 65,000 miles of vessels that comprise your circulatory system, 3 times every minute.
3) Heart Cross Section Revealing Valve and Nerve - 3D visualization based on scanned human data of a mid-coronal cut of the heart revealing the heart's nervous system. A natural pacemaker called the sinoatrial (SA) node is responsible for heart's natural cycle of rhythmic contractions. Embedding in the wall of the upper right atrium, it emits regular electrical pulses that race along nervelike cables through the atria, inducing them to contract. The signals pause slightly at a second node before branching left and right, subdividing into a network of modified muscles fibers in the walls of the ventricles.
Interactive by TheVisualMD
2:11
Apo B Animation - English
FHJourneys/YouTube
Lipids and Lipoproteins
TheVisualMD
Lipids & Fats
TheVisualMD
Cross-Section View of LDL Lipoprotein
TheVisualMD
High-Density Lipoprotein (HDL) Molecule
TheVisualMD
Low-Density Lipoprotein (LDL) Molecule
TheVisualMD
Hyperlipidemia
Mark-shea at the wikipedia project
Lipoproteins
Peter Forster
Human Heart
TheVisualMD
APOE Genotype Test
APOE Genotype Test
Also called: Apolipoprotein E Genotyping, APOE Allele E2+E3+E4
The APOE gene provides instructions for making a protein called apolipoprotein E. The protein helps carry cholesterol and other fatty molecules in the blood. Determining APOE genotype helps evaluate genetic risks of developing heart disease. The APOE e4 allele is also the major known risk-factor gene for late-onset Alzheimer's disease.
APOE Genotype Test
Also called: Apolipoprotein E Genotyping, APOE Allele E2+E3+E4
The APOE gene provides instructions for making a protein called apolipoprotein E. The protein helps carry cholesterol and other fatty molecules in the blood. Determining APOE genotype helps evaluate genetic risks of developing heart disease. The APOE e4 allele is also the major known risk-factor gene for late-onset Alzheimer's disease.
{"label":"APOE Genotype Reference Range","scale":"lin","step":0.25,"hideunits":true,"items":[{"flag":"borderline","label":{"short":"\u03b52\/\u03b52","long":"APOE \u03b52\/\u03b52 (\u03b52\/\u03b52)","orientation":"horizontal"},"values":{"min":0,"max":1},"text":"People with this genotype have a decreased risk for cardiovascular disease (strokes, heart attacks), but increased triglycerides levels and a small risk of developing type III hyperlipoproteinemia. Furthermore, The APOE e2\/e2 genotype may provide some protection against Alzheimer\u2019s disease. However, this does not necessarily mean that you won\u2019t develop the disease in the future.","conditions":["High triglycerides levels","Hyperlipoproteinemia type III"]},{"flag":"borderline","label":{"short":"\u03b52\/\u03b54","long":"APOE \u03b52\/\u03b54 (\u03b52\/\u03b54)","orientation":"horizontal"},"values":{"min":1,"max":2},"text":"APOE e2\/e4 genotype is the least common. People with this genotype have neither an increased or decreased risk of developing cardiovascular disease (strokes, heart attacks). Having just one e4 allele means that your risk of developing late-onset AD is approximately two to three times greater than it is for people who don\u2019t have the allele. However, this allele alone is neither sufficient nor necessary for the development of the disease. <br \/>\n","conditions":["Alzheimer's disease","Hyperlipoproteinemia type III"]},{"flag":"normal","label":{"short":"\u03b52\/\u03b53","long":"APOE \u03b52\/\u03b53 (\u03b52\/\u03b53)","orientation":"horizontal"},"values":{"min":2,"max":3},"text":"People with this genotype have a decreased risk for cardiovascular disease (strokes, heart attacks). Furthermore, the APOE e2 allele may provide some protection against Alzheimer\u2019s disease; while the e3 allele is believed to play a neutral role in the development of the disease. However, this does not necessarily mean that you won\u2019t develop Alzheimer\u2019s disease in the future.","conditions":["High triglycerides levels"]},{"flag":"normal","label":{"short":"\u03b53\/\u03b53","long":"APOE \u03b53\/\u03b53 (\u03b53\/\u03b53)","orientation":"horizontal"},"values":{"min":3,"max":4},"text":"APOE e3\/e3 is the most common. People with this genotype have neither an increased or decreased risk of developing cardiovascular disease (strokes, heart attacks) nor Alzheimer\u2019s disease.<br \/>\n","conditions":[]},{"flag":"abnormal","label":{"short":"\u03b53\/\u03b54","long":"APOE \u03b53\/\u03b54 (\u03b53\/\u03b54)","orientation":"horizontal"},"values":{"min":4,"max":5},"text":"The e3\/e4 APOE genotype is associated with increased triglycerides and total cholesterol levels in the blood, which leads to a high risk for cardiovascular disease (strokes, heart attacks). Furthermore, having just one e4 allele means that your risk of developing late-onset Alzheimer's disease is approximately two to three times greater than it is for people who don\u2019t have the allele. However, this allele alone is neither sufficient nor necessary for the development of the disease.<br \/>\n","conditions":["Coronary heart disease","Cardiovascular disease","Stroke","Heart attack","Myocardial infarction","Metabolic syndrome","Atherosclerosis","Type III hyperlipoproteinemia","Familial dysbetalipoproteinemia","Alzheimer's disease","Late-onset Alzheimer's disease"]},{"flag":"abnormal","label":{"short":"\u03b54\/\u03b54","long":"APOE \u03b54\/\u03b54 (\u03b54\/\u03b54)","orientation":"horizontal"},"values":{"min":5,"max":6},"text":"The e4\/e4 APOE genotype is associated with increased triglycerides and total cholesterol levels in the blood, which leads to a high risk for cardiovascular disease (strokes, heart attacks). Furthermore, having two e4 alleles means that your risk of developing late-onset Alzheimer's disease is approximately ten to fifteen times greater than it is for people who don\u2019t have the allele. However, this allele alone is neither sufficient nor necessary for the development of the disease.","conditions":["Coronary Heart Disease","Cardiovascular disease","Stroke","Heart attack","Myocardial infarction","Metabolic syndrome","Atherosclerosis","Type III hyperlipoproteinemia","Familial dysbetalipoproteinemia","Alzheimer's disease","Late-onset Alzheimer's disease"]}],"value":2.5}[{"borderline":1},{"borderline":0},{"normal":1},{"normal":0},{"abnormal":0},{"abnormal":1}]
Use the slider below to see how your results affect your
health.
Your result is APOE ε2/ε3 (ε2/ε3).
People with this genotype have a decreased risk for cardiovascular disease (strokes, heart attacks). Furthermore, the APOE e2 allele may provide some protection against Alzheimer’s disease; while the e3 allele is believed to play a neutral role in the development of the disease. However, this does not necessarily mean that you won’t develop Alzheimer’s disease in the future.
Related conditions
High triglycerides levels
Apolipoprotein E (APOE) gene is located on chromosome 19 and is involved in making a protein that helps carry lipids in your bloodstream, such as cholesterol and tryglicerids.
There are at least three slightly different versions (alleles) of the APOE gene. The major alleles are called e2, e3, and e4. Each person has two copies of the APOE gene, which can be the same or different. Therefore, a combination of these alleles give 6 possible APOE genotypes: e2/e2, e2/e3, e2/e4, e3/e3, e3/e4, and e4/e4. The most common genotype is e3/e3, while the least common is e2/e4.
The APOE e4 allele is the major known risk-factor gene for late-onset Alzheimer's disease. People who have at least one copy of the e4 allele are also at greater risk of developing heart disease, and have high LDL cholesterol and triglyceride levels.
An APOE genotype test evaluates a person's blood to determine what combination of APOE alleles they have.
Your doctor may want to order an APOE genotype test in conjunction with other exams in the following situations:
If you have been diagnosed with coronary heart disease (CHD) before the age of 45 years in men and 55 years in women.
If you have high total cholesterol and triglyceride levels, but do not respond to treatment with medication and lifestyle changes.
When you have progressive symptoms of dementia that could be attributed to Alzheimer’s disease. However, in this case, the usefulness of this test is still being researched.
A needle will be used to take a blood sample from a vein in your arm.
No fasting or other preparations are needed.
You may feel a little sting when the needle is inserted and extracted but otherwise is a quick procedure. You may also experience bruising and a little bleeding, as well as mild soreness for a short amount of time after the extraction.
APOE e2/e2
Coronary Heart Risk:
The APOE e2/e2 genotype is associated with increased triglycerides and reduced total cholesterol levels in the blood. Usually, people with this genotype have a decreased risk for cardiovascular disease (strokes, heart attacks) and respond well to treatment with a class of lipid-lowering drugs called statins.
Conversely, in people with the e2/e2 genotype, extremely low-fat diets can increase small dense LDL levels (bad cholesterol levels), and therefore these individuals should have a moderate fat restriction.
Alzheimer’s Disease Risk:
The APOE e2/e2 genotype may provide some protection against Alzheimer’s disease. However, this does not necessarily mean that you won’t develop the disease in the future.
APOE e2/e3
Coronary Heart Risk:
The e2/e3 genotype is associated with increased triglycerides and reduced total cholesterol levels in the blood. Usually, people with this genotype have a decreased risk for cardiovascular disease (strokes, heart attacks) and respond well to treatment with a class of lipid-lowering drugs called statins.
Conversely, in people with the e2/e3 genotype, extremely low-fat diets can increase small dense LDL levels (bad cholesterol levels), and therefore these individuals should have a moderate fat restriction.
Alzheimer’s Disease Risk:
The APOE e2 allele may provide some protection against Alzheimer’s disease; while the e3 allele is believed to play a neutral role in the development of the disease.
However, this does not necessarily mean that you won’t develop Alzheimer’s disease in the future.
APOE e2/e4
Coronary Heart Risk:
APOE e2/e4 genotype is the least common. People with this genotype have neither an increased or decreased risk of developing cardiovascular disease (strokes, heart attacks).
Alzheimer’s Disease Risk:
The APOE e4 allele is associated with an increased risk for Alzheimer’s disease (AD), particularly of late-onset (AD that develops after the age of 65). Having just one e4 allele means that your risk of developing late-onset AD is approximately two to three times greater than it is for people who don’t have the allele.
However, this allele alone is neither sufficient nor necessary for the development of the disease.
APOE e3/e3
Coronary Heart Risk:
APOE e3/e3 genotype is the most common. People with this genotype have neither an increased or decreased risk of developing cardiovascular disease (strokes, heart attacks).
Alzheimer’s Disease Risk:
People with the APOE e3/e3 genotype have neither an increased or decreased risk of developing Alzheimer’s disease.
APOE e3/e4
Coronary Heart Risk:
The e3/e4 APOE genotype is associated with increased triglycerides and total cholesterol levels in the blood, which leads to a high risk for cardiovascular disease (strokes, heart attacks).
These individuals respond poorly to treatment with a class of lipid-lowering drugs called statins; however, they respond well to extremely low-fat diets.
Alzheimer’s Disease Risk:
The APOE e4 allele is associated with an increased risk for Alzheimer’s disease (AD), particularly of late-onset (AD that develops after the age of 65). Having just one e4 allele means that your risk of developing late-onset AD is approximately two to three times greater than it is for people who don’t have the allele.
However, this allele alone is neither sufficient nor necessary for the development of the disease.
APOE e4/e4
Coronary Heart Risk:
The e4/e4 APOE genotype is associated with increased triglycerides and total cholesterol levels in the blood, which leads to a high risk for cardiovascular disease (strokes, heart attacks).
These individuals respond poorly to treatment with a class of lipid-lowering drugs called statins; however, they respond well to extremely low-fat diets.
Alzheimer’s Disease Risk:
The APOE e4 allele is associated with an increased risk for Alzheimer’s disease (AD), particularly of late-onset (AD that develops after the age of 65). Having two e4 alleles means that your risk of developing late-onset AD is approximately ten to fifteen times greater than it is for people who don’t have the allele.
However, this allele alone is neither sufficient nor necessary for the development of the disease.
http://www.clevelandheartlab.com/wp-content/uploads/2017/03/ApoE-Patient-OnePager-CHL-P020.pdf [accessed on Sep 21, 2018]
APOE gene - Genetics Home Reference - NIH [accessed on Sep 21, 2018]
APOE Genotyping, Cardiovascular Disease [accessed on Sep 21, 2018]
APOE Genotyping, Alzheimer Disease [accessed on Sep 21, 2018]
Alzheimer's Disease Genetics Fact Sheet [accessed on Sep 21, 2018]
503935: Apo E Genotyping: Cardiovascular Risk | LabCorp [accessed on Sep 21, 2018]
What APOE Means for Your Health | Cognitive Vitality | Alzheimer's Drug Discovery Foundation [accessed on Sep 21, 2018]
APOEG - Clinical: Apolipoprotein E Genotyping, Blood [accessed on Sep 21, 2018]
Apolipoprotein E Genotype and Cardiovascular Diseases in the Elderly [accessed on Sep 21, 2018]
http://www.clevelandheartlab.com/wp-content/uploads/2017/01/ApoE-Practitioner-One-Pager-CHL-D023c.pdf [accessed on Sep 21, 2018]
Apolipoprotein E Genotyping Test [accessed on Sep 21, 2018]
Normal reference ranges can vary depending on the laboratory and the method used for testing. You must use the range supplied by the laboratory that performed your test to evaluate whether your results are "within normal limits."
Additional Materials (1)
How APOE4 Contributes to Alzheimer’s Risk
Video by Cell Press/YouTube
4:32
How APOE4 Contributes to Alzheimer’s Risk
Cell Press/YouTube
Lipid Tests
Lipid Tests
Also called: Lipid Panel, Lipid Profile, Lipid Testing, Lipoprotein Profile
Lipid tests measure triglycerides, a type of fat found in the bloodstream, and cholesterol, a waxy, fat-like substance found in your blood and every cell of your body. High levels of triglycerides and/or a type of cholesterol, called LDL can put you at risk for heart disease.
Lipid Tests
Also called: Lipid Panel, Lipid Profile, Lipid Testing, Lipoprotein Profile
Lipid tests measure triglycerides, a type of fat found in the bloodstream, and cholesterol, a waxy, fat-like substance found in your blood and every cell of your body. High levels of triglycerides and/or a type of cholesterol, called LDL can put you at risk for heart disease.
https://www.nhlbi.nih.gov/health-topics/high-blood-cholesterol [accessed on Sep 29, 2019]
https://www.ncbi.nlm.nih.gov/books/NBK351/ [accessed on Sep 29, 2019]
Additional Materials (12)
Lipid Panel Interpretation
Video by FatIsNotYourFault/YouTube
WellnessFX Biomarker Series: Apolipoprotein B
Video by WellnessFX/YouTube
Cholesterol - what is it and how can you prevent high cholesterol?
Video by Healthchanneltv / cherishyourhealthtv/YouTube
Cholesterol Good and Bad
Video by The National Library of Medicine/YouTube
Cholesterol Blood Test
Video by Baptist Health Physician Partners/YouTube
Cholesterol Isn't Quite as Bad as You've Been Told
Video by Healthcare Triage/YouTube
This browser does not support the video element.
Cholesterol & Atherosclerosis
While the term technically refers to any disease that affects the cardiovascular system (as used in MeSH), it is usually used to refer to those related to atherosclerosis (arterial disease). Everyone talks about high cholesterol and how bad it is for you. But why is it bad for you? Where does it come from? What's the difference between "good" and "bad" cholesterol? Take a journey inside the body and explore its vessels, as world-renowned doctors explain what cholesterol is all about and how it contributes to hardening of the arteries, a dangerous condition also known as atherosclerosis.
Video by TheVisualMD
What cholesterol is and what cholesterol blood tests show
Video by Bupa Health UK/YouTube
This browser does not support the video element.
What Is HDL and LDL Cholesterol?
This video explains the difference between HDL and LDL cholesterol. It also reveals what may occur when there are high levels of LDL in the body.LDL may stick to an artery's inner wall causing the build up of plaque, affecting blood flow. When an artery stiffens and constricts, aneurysm, heart attack, and stroke can occur.
Video by TheVisualMD
This browser does not support the video element.
Fiber and Lowering Cholesterol
Take steps towards better health exploring why a diet rich in soluble fiber is a great way to help lower "bad" LDL cholesterol. Soluble fiber (found in oats, apples, beans, barley) acts like a cholesterol sponge, soaking up "bad" LDL cholesterol in the small intestine and lowering the risk of cardiovascular disease. It can also help regulate blood sugar and reduce the risk of type 2 diabetes.
Video by TheVisualMD
Fasting for a Blood Test | WebMD
Video by WebMD/YouTube
Fasting Plasma Glucose
Fasting Plasma Glucose - The fasting plasma glucose (FPG) test, also known as the fasting blood sugar test, measures blood sugar levels and is used to diagnose diabetes.
Image by TheVisualMD
1:16:38
Lipid Panel Interpretation
FatIsNotYourFault/YouTube
1:13
WellnessFX Biomarker Series: Apolipoprotein B
WellnessFX/YouTube
2:42
Cholesterol - what is it and how can you prevent high cholesterol?
Healthchanneltv / cherishyourhealthtv/YouTube
3:01
Cholesterol Good and Bad
The National Library of Medicine/YouTube
3:06
Cholesterol Blood Test
Baptist Health Physician Partners/YouTube
5:09
Cholesterol Isn't Quite as Bad as You've Been Told
Healthcare Triage/YouTube
3:08
Cholesterol & Atherosclerosis
TheVisualMD
3:53
What cholesterol is and what cholesterol blood tests show
Bupa Health UK/YouTube
0:45
What Is HDL and LDL Cholesterol?
TheVisualMD
1:07
Fiber and Lowering Cholesterol
TheVisualMD
0:50
Fasting for a Blood Test | WebMD
WebMD/YouTube
Fasting Plasma Glucose
TheVisualMD
Triglycerides Test
Triglycerides Test
Also called: TRIG
A triglycerides test measures the amount of triglycerides in your blood. High triglyceride levels may put you at risk for heart disease. The test is usually part of a lipid profile.
Triglycerides Test
Also called: TRIG
A triglycerides test measures the amount of triglycerides in your blood. High triglyceride levels may put you at risk for heart disease. The test is usually part of a lipid profile.
{"label":"Triglycerides Reference Range","scale":"lin","step":0.1,"hideunits":false,"units":[{"printSymbol":"mg\/dL","code":"mg\/dL","name":"milligram per deciliter"}],"items":[{"flag":"normal","label":{"short":"O","long":"Optimal","orientation":"horizontal"},"values":{"min":0,"max":150},"text":"For adults, triglyceride levels less than 150 mg\/dL (milligrams per deciliter) are considered optimal.","conditions":[]},{"flag":"borderline","label":{"short":"B","long":"Borderline","orientation":"horizontal"},"values":{"min":150,"max":200},"text":"Triglycerides levels between 150-199 mg\/dL are considered borderline.","conditions":[]},{"flag":"abnormal","label":{"short":"H","long":"High","orientation":"horizontal"},"values":{"min":200,"max":500},"text":"Triglyceride levels between 200-499 mg\/dL are considered high and levels more than 500 mg\/dL are considered very high. Higher than normal triglyceride levels may put you at risk for heart disease.","conditions":["Physical Inactivity","Obesity","Smoking","Alcohol Abuse","Type 2 Diabetes","Kidney Disease"]},{"flag":"abnormal","label":{"short":"Vh","long":"Very high","orientation":"horizontal"},"values":{"min":500,"max":800},"text":"Triglyceride levels between 200-499 mg\/dL are considered high and levels more than 500 mg\/dL are considered very high. Higher than normal triglyceride levels may put you at risk for heart disease.","conditions":["Physical Inactivity","Obesity","Smoking","Alcohol Abuse","Type 2 Diabetes","Kidney Disease"]}],"value":75}[{"normal":0},{"borderline":0},{"abnormal":0},{"abnormal":1}]
Use the slider below to see how your results affect your
health.
mg/dL
150
200
500
Your result is Optimal.
For adults, triglyceride levels less than 150 mg/dL (milligrams per deciliter) are considered optimal.
Related conditions
A triglycerides test measures the amount of triglycerides in your blood. Triglycerides are a type of fat in your body. If you eat more calories than you need, the extra calories are changed into triglycerides. These triglycerides are stored in your fat cells for later use. When your body needs energy, triglycerides are released into your bloodstream to provide fuel for your muscles to work. If you eat more calories than you burn off, especially calories from carbohydrates and fats, you may get high triglyceride levels in your blood. High triglycerides may put you at greater risk for a heart attack or stroke.
A triglycerides test is usually part of a lipid profile. Lipid is another word for fat. A lipid profile is a test that measures the level of fats in your blood, including triglycerides and cholesterol, a waxy, fatty substance found in every cell of your body. If you have high levels of both LDL (bad) cholesterol and triglycerides, you may be at an increased risk for a heart attack or stroke.
Your health care provider may order a lipid profile as part of a routine exam or to diagnose or monitor heart conditions.
Healthy adults should get a lipid profile, which includes a triglycerides test, every four to six years. You may need to be tested more often if you have certain risk factors for heart disease. These include:
Family history of heart disease
Smoking
Being overweight
Unhealthy eating habits
Lack of exercise
Diabetes
High blood pressure
Age. Men 45 years or older and women 50 years or older are at a higher risk for heart disease
A triglycerides test is a blood test. During the test, a health care professional will take a blood sample from a vein in your arm, using a small needle. After the needle is inserted, a small amount of blood will be collected into a test tube or vial. You may feel a little sting when the needle goes in or out. This usually takes less than five minutes.
You may need to fast (not food or drink) for 9 to 12 hours before your blood is drawn. Your health care provider will let you know if you need to fast and if there are any special instructions to follow.
There is very little risk to having a blood test. You may have slight pain or bruising at the spot where the needle was put in, but most symptoms go away quickly.
Triglycerides are usually measured in milligrams (mg) of triglycerides per deciliter (dL) of blood. For adults, results are usually categorized as:
Normal/desirable triglyceride range: less than 150mg/dL
Borderline high triglyceride range: 150 to 199 mg/dL
High triglyceride range: 200 to 499 mg/dL
Very high triglyceride range: 500 mg/dL and above
Higher than normal triglyceride levels may put you at risk for heart disease. To reduce your levels and lower your risk, your health care provider may recommend lifestyle changes and/or prescribe medicines.
If your results were borderline high, your provider may recommend that you:
Lose weight
Eat a healthier diet
Get more exercise
Reduce alcohol intake
Take a cholesterol lowering medicine
If your results were high or very high, your provider may recommend the same lifestyle changes as above and also that you:
Follow a very low-fat diet
Lose a significant amount of weight
Take medicine or medicines designed to lower triglycerides
Be sure to talk to your health care provider before making any major changes to your diet or exercise routine.
Triglycerides Test: MedlinePlus Medical Test [accessed on May 17, 2022]
Normal reference ranges can vary depending on the laboratory and the method used for testing. You must use the range supplied by the laboratory that performed your test to evaluate whether your results are "within normal limits."
Additional Materials (39)
Triglycerides
A Triglyceride model showing the positions of Sn1, Sn2 and Sn3, fatty acids, and the glycerol backbone
Image by Roger Daniels, Bunge Oils Director of Research & Development
Excess fat cells growing on top of the muscle tissue
Triglycerides are a large and varied category of fats found in both plants and animals. Because fats and blood, like oil and water, do not mix, triglycerides (as well as cholesterol) circulate through the body in special parcels called lipoproteins, which are fat-and-protein packages that enable fats to move freely within the bloodstream. Proteins and other components make up the outer shell; fats, in the form of triglycerides and cholesterol, are packed together inside.
Image by TheVisualMD
Lipids and Lipoproteins
Lipids and Lipoproteins
Image by TheVisualMD
This browser does not support the video element.
Lipids, Heart Health and Baselining Your Health
Your blood "knows" what you eat, meaning that the cardiovascular system is a sensitive barometer of a person's health, including diet. What individuals eat is reflected in their blood chemistry and the health of their heart, arteries and vessels. Fats (also known as lipids), for example, are vital to health and wellbeing throughout our lives and yet they are mostly associated with obesity and cardiovascular disease. The problem is that not all fats (or cholesterol) are equal. They share basic chemical similarities, but they also have important differences, which, in turn, result in different roles and effects in the body. Tests that offer information on diet and heart health include total cholesterol, low-density lipoprotein (LDL or "bad" cholesterol), high-density lipoprotein (HDL or "good" cholesterol), and triglycerides.
Video by TheVisualMD
Thoracic Duct
The lymphatic system consists of a network of vessels and nodes that collect and carry a clear fluid called lymph that plays roles in immune function as well as the transport of nutrients. The thoracic duct, which is the largest vessel in the lymphatic system, delivers lymph into the bloodstream, including lymph from the intestinal system, called chyle, which is milky rich in fats.
Image by TheVisualMD
Triglyceride Molecule
Triglycerides are the body's primary form of stored fat. When you consume excess calories, your body converts them right away into triglycerides. In the liver, triglycerides are packaged up with cholesterol and with proteins in carriers called lipoproteins, which are transported through the blood to various sites of the body to be stored in fat cells. Luckily for anyone with a high triglyceride reading in their lipid profile, levels can often be lowered by making smart changes to the diet. Even if you are prescribed medication to lower triglyceride levels, your physician will also recommend improving food choices. In this model, carbon atoms are dark gray, hydrogen atoms are white, and oxygen atoms are red.
Image by TheVisualMD
Triglyceride Molecule
Triglycerides are the body's primary form of stored fat. When you consume excess calories, your body converts them right away into triglycerides. In the liver, triglycerides are packaged up with cholesterol and with proteins in carriers called lipoproteins, which are transported through the blood to various sites of the body to be stored in fat cells. Luckily for anyone with a high triglyceride reading in their lipid profile, levels can often be lowered by making smart changes to the diet. Even if you are prescribed medication to lower triglyceride levels, your physician will also recommend improving food choices. In this model, carbon atoms are dark gray, hydrogen atoms are white, and oxygen atoms are red.
Image by TheVisualMD
Lowering Triglycerides - Mayo Clinic
Video by Mayo Clinic/YouTube
Tri HDL
Video by ACAP Health/YouTube
Triglycerides: Liver and Intestines
The liver is the body's central chemical plant, removing toxins, storing sugars and lipids and producing a wide range of proteins that play key roles as enzymes. The liver also produces packages cholesterol and triglycerides, along with special proteins, into lipoproteins.
Image by TheVisualMD
Triglycerides: Triglyceride
Triglycerides are a large and varied category of fats found in both plants and animals. When we eat our bodies convert excess calories into triglycerides, which can be stored in fat cells and then released as needed into the bloodstream for energy between meals.
Image by TheVisualMD
LDL-Particles: Triglycerides
One factor that may contribute to a high LDL particle count is raised levels of triglycerides. Elevated triglyceride levels in the blood start a chain of biochemical reactions that eventually leads to a reduction in the size of LDL particles. The smaller LDL particles can't carry as much cholesterol as larger LDL particles, so a greater number of them is needed to carry a given amount of cholesterol.
Image by TheVisualMD
Triglycerides and HDL
Video by Joslin Diabetes Center/YouTube
Asian Heart Hospital - What is Triglycerides?
Video by Asian Heart Institute/YouTube
What is Plaque?
Video by CardioTabs/YouTube
Lipid Absorption
Lipid Absorption
Image by OpenStax College
lipid vesicles in these adipocytes
The preadipocyte cell line PA6 fully differentiated into adipocytes. The lipid vesicles in these adipocytes are stained using oil-red-O staining.
Image by M. Oktar Guloglu
Anatomy of a Lipoprotein
Lipoproteins transport cholesterol, triglycerides, or other lipids through the bloodstream. Lipoproteins are protein spheres that consist of a core of triglycerides and cholesterol esters, surrounded by a shell made up of water-soluble phospholipids with embedded proteins and cholesterol. The lipid-laden core of the lipoprotein is insoluble in aqueous (water-based) blood, so the phospholipid-protein shell is necessary to allow the lipoprotein to float freely in the bloodstream.
Image by TheVisualMD
Anatomy of a Lipoprotein
Lipoproteins transport cholesterol, triglycerides, or other lipids through the bloodstream. Lipoproteins are protein spheres that consist of a core of triglycerides and cholesterol esters, surrounded by a shell made up of water-soluble phospholipids with embedded proteins and cholesterol. The lipid-laden core of the lipoprotein is insoluble in aqueous (water-based) blood, so the phospholipid-protein shell is necessary to allow the lipoprotein to float freely in the bloodstream.
Image by TheVisualMD
Anatomy of a Lipoprotein
Lipoproteins transport cholesterol, triglycerides, or other lipids through the bloodstream. Lipoproteins are protein spheres that consist of a core of triglycerides and cholesterol esters, surrounded by a shell made up of water-soluble phospholipids with embedded proteins and cholesterol. The lipid-laden core of the lipoprotein is insoluble in aqueous (water-based) blood, so the phospholipid-protein shell is necessary to allow the lipoprotein to float freely in the bloodstream.
Image by TheVisualMD
Anatomy of a Lipoprotein
Lipoproteins transport cholesterol, triglycerides, or other lipids through the bloodstream. Lipoproteins are protein spheres that consist of a core of triglycerides and cholesterol esters, surrounded by a shell made up of water-soluble phospholipids with embedded proteins and cholesterol. The lipid-laden core of the lipoprotein is insoluble in aqueous (water-based) blood, so the phospholipid-protein shell is necessary to allow the lipoprotein to float freely in the bloodstream.
Image by TheVisualMD
Breast Milk Component Pathway
The components of breast milk are brought together in the alveoli via different routes. Breast milk constituents are either absorbed from the bloodstream from nutrients in the mother's diet or synthesized in special milk-producing cells called lactocytes. These constituents are brought together in the alveoli via different routes. Some components pass through or between the lactocytes, while others are assembled within the lactocytes.
Image by TheVisualMD
Maintaining Cardiovascular Health
This series of images illustrates diet and lifestyle changes that help maintain cardiovascular health, and which may actually help improve existing damage. From left to right: 1) A woman eats an apple, with visible cardiovascular system and digestive system. 2) Fresh vegetables, including tomatoes, peppers, broccoli, cauliflower and carrots, are high in fiber which helps keep blood lipid levels healthy. 3) Monounsaturated and polyunsaturated fats are better for heart health than trans fats and saturated fats. Good sources include those shown: nuts, seeds, olive oil and omega-3 fatty acids like those found in salmon. 4) A woman takes a vigorous walk with muscles, skeletal bones and heart visible. Regular exercise in combination with a heart-healthy diet helps keep your heart and blood vessels in top condition.
Image by TheVisualMD
Fat Cells Growing on the Surface of a Blood Vessel
This image shows mature fat cells growing on the surface of a blood vessel. The image is from an animation that shows how fat cells, or adipocytes, expand and contribute to obesity. Some tissue is also visible in the image.
Image by TheVisualMD
Healthy Cell Membrane
This image shows the healthy membrane of an endothelial cell in a blood vessel wall. You can see the semi-permeable double layer of phospholipids that allows lipids to move across the membrane. The cholesterol molecules (yellow) maintain permeability by keeping the phospholipid tails from sticking together.
Managing Atherosclerosis Risk : Certain lifestyle habits, traits, and conditions may increase the probability that you'll develop atherosclerosis. These conditions are known as risk factors. The more risk factors you have, the greater your chances of developing atherosclerosis. Fortunately, most of these risk factors are within your control.
Image by TheVisualMD
Abnormal blood lipid levels and hypertension both increase the risk of atherosclerosis
Message From The Heart : Abnormal blood lipid levels and hypertension both increase the risk of atherosclerosis. In atherosclerosis, cholesterol and other substances create hard, waxy plaques inside your arteries, narrowing them and making it more difficult for blood to get through.
Image by TheVisualMD
Fat: What Is It Good For?
Adipose tissue (fat tissue) is a type of connective tissue. The two main types of adipose tissue in humans are subcutaneous (under the skin) and visceral (inside the abdomen). Adipose tissue performs many functions in your body. Its main job is to store energy in the form of lipids (triglycerides and cholesterol). When you eat fatty foods, often there are more lipids than you need for energy at that time. The excess lipids are stored in your adipose tissue. The same holds true for proteins and carbohydrates—when you eat more of them than you need immediately, excess amounts are converted to lipids and stored in adipose tissue for future use.
Image by TheVisualMD
Coronary Artery Disease - Risk Factors Of Atherosclerosis
Risk Factors Of Atherosclerosis : Scientists think that immune system cells may gather at injures areas of the lining of the arteries in an attempt to "heal" the damage. Lipids like cholesterol adhere as well, together with other substances in the blood like calcium and fibrin (connective tissue). Together they form the hard, fatty deposit called plaques.
Image by TheVisualMD
Getting to the Heart of Things
The cardiovascular system consists of the heart, the blood vessels, and the blood itself. Blood is mostly made up of plasma and red and white blood cells. But it contains many other substances as well, like platelets, hormones, and nutrients such as glucose. The cardiovascular system distributes these substances throughout the body as needed and collects waste products from your cells for elimination.
Image by TheVisualMD
Obese Child Showing Cardiovascular System and Visceral Fat
Most of the kids diagnosed with type 2 diabetes are obese. Normally, insulin in the blood binds with an insulin receptor on a cell surface to allow glucose (blood sugar) to enter the cell. In type 2 diabetes, insulin doesn't work to allow glucose into the cell. Obesity and its related conditions, such as high blood pressure, abnormal glucose tolerance, and high lipid levels, are major risk factors for cardiovascular disease (CVD), diseases of the heart and blood vessels. Most of us think of CVD, the leading cause of death in the US, as an adult disease. But CVD can begin early on, even in childhood, and get progressively worse. Obese children and children with abnormally high blood cholesterol and triglyceride levels can develop fatty streaks in their arteries, the first steps in the formation of plaques. Some may even develop plaques. CVD has become a pediatric disease.
Image by TheVisualMD
Obese Young Child Showing Cardiovascular System and Visceral Fat
Most of the kids diagnosed with type 2 diabetes are obese. Normally, insulin in the blood binds with an insulin receptor on a cell surface to allow glucose (blood sugar) to enter the cell. In type 2 diabetes, insulin doesn't work to allow glucose into the cell. Obesity and its related conditions, such as high blood pressure, abnormal glucose tolerance, and high lipid levels, are major risk factors for cardiovascular disease (CVD), diseases of the heart and blood vessels. Most of us think of CVD, the leading cause of death in the US, as an adult disease. But CVD can begin early on, even in childhood, and get progressively worse. Obese children and children with abnormally high blood cholesterol and triglyceride levels can develop fatty streaks in their arteries, the first steps in the formation of plaques. Some may even develop plaques. CVD has become a pediatric disease.
Image by TheVisualMD
Lipoproteins
Lipoproteins are protein spheres that transport lipids through your bloodstream.
Image by TheVisualMD
Bile Acids
Digestion of Fats : You need cholesterol in order to digest food. One of the other major uses of cholesterol is the production of bile acids (also known as bile salts) in the liver. Bile contains a number of ingredients, including water, cholesterol, and bile acids. Bile is necessary for the absorption of fats from fecal matter passing through the intestine.
Image by TheVisualMD
Statins Lowering Cholesterol
Statins lower cholesterol levels by reducing the production of cholesterol by the liver. They also increase the capacity of the liver to remove cholesterol from the blood. When less produced and more gets removed from the bloodstream, the level of cholesterol can drop significantly.
Image by TheVisualMD
Cardiovascular disease
Atherosclerosis Risk Factors, Major Risk Factors You Can Control:
Image by TheVisualMD
Triglyceride Molecule
Triglycerides are the body's primary form of stored fat. When you consume excess calories, your body converts them right away into triglycerides. In the liver, triglycerides are packaged up with cholesterol and with proteins in carriers called lipoproteins, which are transported through the blood to various sites of the body to be stored in fat cells. Luckily for anyone with a high triglyceride reading in their lipid profile, levels can often be lowered by making smart changes to the diet. Even if you are prescribed medication to lower triglyceride levels, your physician will also recommend improving food choices. In this model, carbon atoms are dark gray, hydrogen atoms are white, and oxygen atoms are red
Image by TheVisualMD
The ABC's of Vitamins
Image by TheVisualMD
Triglycerides
Roger Daniels, Bunge Oils Director of Research & Development
Excess fat cells growing on top of the muscle tissue
TheVisualMD
Lipids and Lipoproteins
TheVisualMD
2:46
Lipids, Heart Health and Baselining Your Health
TheVisualMD
Thoracic Duct
TheVisualMD
Triglyceride Molecule
TheVisualMD
Triglyceride Molecule
TheVisualMD
2:46
Lowering Triglycerides - Mayo Clinic
Mayo Clinic/YouTube
2:17
Tri HDL
ACAP Health/YouTube
Triglycerides: Liver and Intestines
TheVisualMD
Triglycerides: Triglyceride
TheVisualMD
LDL-Particles: Triglycerides
TheVisualMD
3:25
Triglycerides and HDL
Joslin Diabetes Center/YouTube
3:11
Asian Heart Hospital - What is Triglycerides?
Asian Heart Institute/YouTube
2:19
What is Plaque?
CardioTabs/YouTube
Lipid Absorption
OpenStax College
lipid vesicles in these adipocytes
M. Oktar Guloglu
Anatomy of a Lipoprotein
TheVisualMD
Anatomy of a Lipoprotein
TheVisualMD
Anatomy of a Lipoprotein
TheVisualMD
Anatomy of a Lipoprotein
TheVisualMD
Breast Milk Component Pathway
TheVisualMD
Maintaining Cardiovascular Health
TheVisualMD
Fat Cells Growing on the Surface of a Blood Vessel
Abnormal blood lipid levels and hypertension both increase the risk of atherosclerosis
TheVisualMD
Fat: What Is It Good For?
TheVisualMD
Coronary Artery Disease - Risk Factors Of Atherosclerosis
TheVisualMD
Getting to the Heart of Things
TheVisualMD
Obese Child Showing Cardiovascular System and Visceral Fat
TheVisualMD
Obese Young Child Showing Cardiovascular System and Visceral Fat
TheVisualMD
Lipoproteins
TheVisualMD
Bile Acids
TheVisualMD
Statins Lowering Cholesterol
TheVisualMD
Cardiovascular disease
TheVisualMD
Triglyceride Molecule
TheVisualMD
The ABC's of Vitamins
TheVisualMD
Lipoprotein (A) Test
Lipoprotein (A) Test
Also called: Cholesterol Lp(a), Lp(a), Lp "Little a", lipoprotein (a) blood test
Lipoprotein(a) is a particle that carries cholesterol, proteins and fats in blood vessels. The level of Lp(a) is genetically inherited and not affected by lifestyle or treatment. Lp(a) test allows to assess the risk of heart disease.
Lipoprotein (A) Test
Also called: Cholesterol Lp(a), Lp(a), Lp "Little a", lipoprotein (a) blood test
Lipoprotein(a) is a particle that carries cholesterol, proteins and fats in blood vessels. The level of Lp(a) is genetically inherited and not affected by lifestyle or treatment. Lp(a) test allows to assess the risk of heart disease.
{"label":"Lipoprotein (A) Reference Range","scale":"lin","step":0.1,"hideunits":false,"units":[{"printSymbol":"mg\/dL","code":"mg\/dL","name":"milligram per deciliter"}],"items":[{"flag":"normal","label":{"short":"Normal","long":"Normal","orientation":"horizontal"},"values":{"min":0,"max":30},"text":"Some cholesterol and Lp(a) in your blood is normal.","conditions":[]},{"flag":"abnormal","label":{"short":"High","long":"High","orientation":"horizontal"},"values":{"min":30,"max":100},"text":"High levels of Lp(a) in blood are associated with an increased risk of heart attack, stroke, or narrowed arteries supplying blood to vital organs.","conditions":["Atherosclerosis","Coronary artery disease","Heart attack","Peripheral vascular disease","Aortic stenosis","Thrombosis","Stroke"]}],"value":15}[{"normal":0},{"abnormal":0}]
Use the slider below to see how your results affect your
health.
mg/dL
30
Your result is Normal.
Some cholesterol and Lp(a) in your blood is normal.
Related conditions
A lipoprotein (a) test measures the level of lipoprotein (a) in your blood. Lipoproteins are substances made of protein and fat that carry cholesterol through your bloodstream. There are two main types of cholesterol:
High-density lipoprotein (HDL), or "good" cholesterol
Low-density lipoprotein (LDL), or "bad" cholesterol.
Lipoprotein (a) is a type of LDL (bad) cholesterol. A high level of lipoprotein (a) may mean you are at risk for heart disease.
A lipoprotein (a) test is used to check for risk of stroke, heart attack, or other heart diseases. It is not a routine test. It is usually only given to people who have certain risk factors, such as a family history of heart disease.
You may need this test if you have:
Heart disease, despite normal results on other lipid tests
High cholesterol, despite maintaining a healthy diet
A family history of heart disease, especially heart disease that has occurred at an early age and/or sudden deaths from heart disease
A health care professional will take a blood sample from a vein in your arm, using a small needle. After the needle is inserted, a small amount of blood will be collected into a test tube or vial. You may feel a little sting when the needle goes in or out. This usually takes less than five minutes.
You don't need any special preparations for a lipoprotein (a) test. If your health care provider has ordered other tests, such as a cholesterol test, you may need to fast (not eat or drink) for 9 to 12 hours before your blood is drawn. Your health care provider will let you know if there are any special instructions to follow.
There is very little risk to having a blood test. You may experience slight pain or bruising at the spot where the needle was put in, but most symptoms go away quickly.
A high lipoprotein (a) level may mean you are at risk for heart disease. There are no specific treatments to lower lipoprotein (a). Your level of lipoprotein (a) is determined by your genes and is not affected by your lifestyle or by most medicines. But if your test results show a high level of lipoprotein (a), your health care provider may make recommendations to reduce other risk factors that can lead to heart disease. These may include medicines or lifestyle changes such as:
Eating a healthy diet
Weight Control
Quitting smoking
Getting regular exercise
Reducing stress
Lowering blood pressure
Reducing LDL cholesterol
Certain situations and factors can affect your test results. You should not get a lipoprotein (a) test if you have any of these conditions:
Fever
Infection
Recent and considerable weight loss
Pregnancy
Lipoprotein (a) Blood Test: MedlinePlus Lab Test Information [accessed on Sep 09, 2018]
120188: Lipoprotein(a) | LabCorp [accessed on Sep 09, 2018]
https://www.labcorp.com/tests/related-documents/L15045 [accessed on Sep 09, 2018]
Understand Inherited Lipoprotein(a) - Lipoprotein(a) Foundation [accessed on Sep 09, 2018]
Normal reference ranges can vary depending on the laboratory and the method used for testing. You must use the range supplied by the laboratory that performed your test to evaluate whether your results are "within normal limits."
Additional Materials (10)
Lipids and Lipoproteins
Lipids and Lipoproteins
Image by TheVisualMD
Lipoprotein Associated Phospholipase: Macrophage
Lp-PLA2 (or lipoprotein-associated phospholipase A2) is an enzyme produced by specialized immune cells called macrophages that engulf and destroy pathogens, foreign particles, aging cells and biological debris.
Image by TheVisualMD
Lp-PLA2, Coronary heart disease
Coronary heart disease is the leading cause of death for both men and women. There is no single biomarker that can perfectly predict a person's risk of heart disease; half of all people who suffer heart attacks have normal cholesterol. This is why researchers have developed additional biomarkers for heart disease, such as Lp-PLA2 (or lipoprotein-associated phospholipase A2), an enzyme linked to the inflammation of blood vessels. Individuals with high levels of Lp-PLA2 are at much higher risk of heart attack and stroke even if their cholesterol levels are normal.
Image by TheVisualMD
Lipoproteins
Lipid logistics: transport of triglycerides and cholesterol in organisms in form of lipoproteins as chylomicrons, VLDL, LDL, IDL, HDL.
Image by Peter Forster
Lipoprotein(a) (Lp(a)) and Stroke
Video by Children's Stroke Foundation/YouTube
Lipoprotein(a) Foundation Thanks Bob Harper ...
Video by BusinessWire/YouTube
What Is Lipoprotein(a)?
Video by Rush University System for Health/YouTube
High Cholesterol Medical Animation (Hyperlipidemia)
Video by Silverback Video/YouTube
What is FH?
Video by NationalLipid/YouTube
Jeanine's Story
Video by Rush University System for Health/YouTube
Lipids and Lipoproteins
TheVisualMD
Lipoprotein Associated Phospholipase: Macrophage
TheVisualMD
Lp-PLA2, Coronary heart disease
TheVisualMD
Lipoproteins
Peter Forster
4:09
Lipoprotein(a) (Lp(a)) and Stroke
Children's Stroke Foundation/YouTube
2:20
Lipoprotein(a) Foundation Thanks Bob Harper ...
BusinessWire/YouTube
3:47
What Is Lipoprotein(a)?
Rush University System for Health/YouTube
1:19
High Cholesterol Medical Animation (Hyperlipidemia)
Silverback Video/YouTube
1:54
What is FH?
NationalLipid/YouTube
2:48
Jeanine's Story
Rush University System for Health/YouTube
Lathosterol Test
Lathosterol Test
Phytosterols, which encompass plant sterols and stanols, are steroid compounds similar to cholesterol which occur in plants and vary only in carbon side chains and/or presence or absence of a double bond. Although there is no direct evidence related to cardiovascular disease, phytosterols have well documented cholesterol-lowering effects. Phytosterol to...
Lathosterol Test
Phytosterols, which encompass plant sterols and stanols, are steroid compounds similar to cholesterol which occur in plants and vary only in carbon side chains and/or presence or absence of a double bond. Although there is no direct evidence related to cardiovascular disease, phytosterols have well documented cholesterol-lowering effects. Phytosterol to...
{"label":"Lathosterol Reference Range","scale":"lin","step":0.1,"hideunits":false,"units":[{"printSymbol":"mg\/L","code":"mg\/L","name":"milligram per liter"}],"items":[{"flag":"normal","label":{"short":"Normal","long":"Normal","orientation":"horizontal"},"values":{"min":0,"max":3},"text":"Normal results vary based on the laboratory and the method used.","conditions":[]},{"flag":"abnormal","label":{"short":"High","long":"High","orientation":"horizontal"},"values":{"min":3,"max":20},"text":"A very high lathosterol result means that your body production of cholesterol is high. Using statins is the recommended drug therapy for this condition.","conditions":[]}],"value":1.5}[{"normal":0},{"abnormal":0}]
Use the slider below to see how your results affect your
health.
mg/L
3
Your result is Normal.
Normal results vary based on the laboratory and the method used.
Related conditions
Cholesterol is an important precursor of hormones in our body. We can synthesize our own cholesterol (synthesis) or get it from the diet (absorption). Excess levels of cholesterol have also been associated with elevated rates of cardiovascular disease. The balance of these molecules is important for the proper functioning of our body. Treatment approach will depend on which path of cholesterol is irregular.
Lathosterol is used to determine your cholesterol synthesis status.
This test helps to assess major lipid disorders or for a better drug treatment response.
A healthcare professional takes a blood sample from a vein, generally in your arm, using a needle. A small amount of blood is collected into a test tube or vial. You may feel discomfort when the needle goes in or out.
You will need to fast for this test (stop eating for at least 8 hours before the blood extraction).
You may have slight pain or bruise at the spot where the needle was inserted, but most symptoms go away quickly.
The normal range is: 0.0-3.0 mg/L
A very high lathosterol result means that your body production of cholesterol is high. Using statins is the recommended drug therapy for this condition.
Low values of lathosterol means that production of cholesterol in the body is low. If total cholesterol levels are high, this means that cholesterol absorption is high. Additional tests may be done to confirm the increase absorption of cholesterol by the intestine.
This test is currently available mostly for research purposes. There is not enough evidence to support this test in patients in general.
Normal reference ranges can vary depending on the laboratory and the method used for testing. You must use the range supplied by the laboratory that performed your test to evaluate whether your results are "within normal limits."
Apolipoprotein B Test
Apolipoprotein B Test
Also called: Apo B, Beta Apolipoprotein
Apolipoprotein B (Apo-B) is the main protein in the LDL cholesterol’s (bad cholesterol) structure. Its primary function is to protect and transport the LDL particles through the bloodstream. An Apo-B test is mainly used to help assess your risk of developing coronary atherosclerosis (CAD) and heart disease.
Apolipoprotein B Test
Also called: Apo B, Beta Apolipoprotein
Apolipoprotein B (Apo-B) is the main protein in the LDL cholesterol’s (bad cholesterol) structure. Its primary function is to protect and transport the LDL particles through the bloodstream. An Apo-B test is mainly used to help assess your risk of developing coronary atherosclerosis (CAD) and heart disease.
{"label":"Apolipoprotein B Reference Range","scale":"lin","step":0.1,"hideunits":false,"units":[{"printSymbol":"mg\/dL","code":"mg\/dL","name":"milligram per deciliter"}],"items":[{"flag":"abnormal","label":{"short":"Low","long":"Low","orientation":"horizontal"},"values":{"min":0,"max":50},"text":"Decreased levels of Apo B indicate a lower risk of developing\u00a0coronary atherosclerosis (CAD) and heart disease. However, this does not mean that you won't develop these conditions in the future.\u00a0","conditions":["Hyperthyroidism","Reye\u2019s syndrome","Abetalipoproteinemia","Cirrhosis","Malnutrition"]},{"flag":"normal","label":{"short":"Normal","long":"Normal","orientation":"horizontal"},"values":{"min":50,"max":123},"text":"Normal results vary based on the laboratory and the method used.","conditions":[]},{"flag":"abnormal","label":{"short":"High","long":"High","orientation":"horizontal"},"values":{"min":123,"max":250},"text":"Elevated levels of Apo B are related to a higher risk of developing\u00a0coronary atherosclerosis (CAD) and heart disease.","conditions":["Familial combined hyperlipidemia","Diabetes","Hypothyroidism","Kidney disease","Atherosclerosis","Coronary Heart Disease","Stroke","Peripheral Vascular Disease","Hypertension","Metabolic Syndrome"]}],"value":86.5}[{"abnormal":0},{"normal":0},{"abnormal":0}]
Use the slider below to see how your results affect your
health.
mg/dL
50
123
Your result is Normal.
Normal results vary based on the laboratory and the method used.
Related conditions
Apolipoproteins are certain types of proteins that play specific roles in the metabolism and transportation of lipids (fat) through the bloodstream.
Apolipoprotein B (Apo-B) is a human protein that is an important component of LDL cholesterol and non-HDL cholesterol (known as “bad” cholesterol”). It takes care of LDL cholesterol particle’s transportation, protection, and structure maintenance.
An Apo-B test measures the levels of apolipoprotein B in a sample of your blood.
Excess LDL cholesterol can lead to fatty deposits (plaques) in the blood vessels walls, which cause the vessels to narrow in a process termed atherosclerosis.
The Apo B test is used to assess an individual's risk of developing coronary atherosclerosis (CAD) and heart disease. Apo B test is normally ordered:
When there is an abnormal increase in other lipid levels (cholesterol, triglycerides) in the blood
To monitor the effectiveness of lipid treatment
In case of existing family history of atherosclerosis/heart diseases
When your blood triglycerides levels are high, testing your LDL cholesterol (LDL-C) levels becomes difficult. In this case, an Apo B test is useful to estimate your blood LDL cholesterol levels because Apo B levels tend to mirror LDL-C levels.
Your doctor may also order this test in case there is a considerable history of heart disease in your family.
A needle will be used to take a blood sample from a vein in your arm.
You may be asked to fast for about 12 hours before the test in case of other lipid tests (cholesterol, triglycerides) are ordered.
You may feel discomfort when the needle is inserted and extracted but otherwise is a quick procedure. You may also experience bruising and a little bleeding, as well as mild soreness for a short amount of time after the blood extraction.
Normal
Normal reference ranges are from 50 to 123 mg/dL.
The levels of Apo B along with non-HDL-C and LDL-C reflect your risk of developing cardiovascular disease.
High
Elevated levels of Apo B are related to a higher risk of developing coronary atherosclerosis (CAD) and heart disease. Increased levels are also associated with:
Familial combined hyperlipidemia (an inherited disorder that causes high cholesterol and triglyceride levels in the blood)
Diabetes
Hypothyroidism (underactive thyroid gland)
Kidney disease
Intake of certain drugs, such as diuretics, androgens, or beta-blockers, among others.
Low
Decreased levels of Apo B indicate a lower risk of developing coronary atherosclerosis (CAD) and heart disease. However, this does not mean that you won't develop these conditions in the future.
Low Apo B levels are also associated with:
Hyperthyroidism (overactive thyroid gland)
Reye’s syndrome (a rare condition that causes sudden swelling in the brain and liver)
Abetalipoproteinemia (a condition that prevents the body from properly absorbing dietary fats)
Cirrhosis (liver scarring)
Malnutrition
Lab Tests Online. APO B. [accessed on Sep 08, 2018]
Mayo Clinic. Test ID: APLB. [accessed on Sep 08, 2018]
Health Line. Apolipoprotein B100. [accessed on Sep 08, 2018]
LabCorp Test Menu. 167015: Apolipoprotein B. [accessed on Sep 08, 2018]
Fontanarosa, P., & Christiansen, S. (2009, April 01). Laboratory Values. AMA Manual of Style. Ed. [accessed on Oct 09, 2018]
Normal reference ranges can vary depending on the laboratory and the method used for testing. You must use the range supplied by the laboratory that performed your test to evaluate whether your results are "within normal limits."
CDC's Expert Commentary on Familial Hypercholesterolemia
Video by Centers for Disease Control and Prevention (CDC)/YouTube
Familial Hypercholesterolemia - English
Video by FHJourneys/YouTube
Apo B Animation - English
Video by FHJourneys/YouTube
The New Marker for Heart Disease that is BETTER than LDL Cholesterol
Video by Dr. Adrian Chavez/YouTube
WellnessFX Biomarker Series: Apolipoprotein B
Video by WellnessFX/YouTube
Lipoproteins
Lipoproteins are protein spheres that transport lipids through your bloodstream.
Image by TheVisualMD
Human Heart Displaying Aorta and Coronary Artery
Apolipoprotein B
Heart Cross Section Revealing Valve and Nerve
1
2
3
Human Heart
1) Human Heart Displaying Aorta and Coronary Artery - 3D visualization based on scanned human data of an anterior view of the heart.
2) Coronary Arteries - Your heart is a hollow, muscular organ whose only job is to pump blood throughout your body. Because every cell in your body must have a never-ending supply of oxygenated blood, your heart never sleeps. It beats about 100,000 times a day, pumping 6 qts of blood through the 65,000 miles of vessels that comprise your circulatory system, 3 times every minute.
3) Heart Cross Section Revealing Valve and Nerve - 3D visualization based on scanned human data of a mid-coronal cut of the heart revealing the heart's nervous system. A natural pacemaker called the sinoatrial (SA) node is responsible for heart's natural cycle of rhythmic contractions. Embedding in the wall of the upper right atrium, it emits regular electrical pulses that race along nervelike cables through the atria, inducing them to contract. The signals pause slightly at a second node before branching left and right, subdividing into a network of modified muscles fibers in the walls of the ventricles.
CDC's Expert Commentary on Familial Hypercholesterolemia
Centers for Disease Control and Prevention (CDC)/YouTube
2:02
Familial Hypercholesterolemia - English
FHJourneys/YouTube
2:11
Apo B Animation - English
FHJourneys/YouTube
5:19
The New Marker for Heart Disease that is BETTER than LDL Cholesterol
Dr. Adrian Chavez/YouTube
1:13
WellnessFX Biomarker Series: Apolipoprotein B
WellnessFX/YouTube
Lipoproteins
TheVisualMD
Human Heart
TheVisualMD
Apolipoprotein A-I Test
Apolipoprotein A-I Test
Also called: Apo A-I, Apolipoprotein A1, Apo-A1
Apolipoprotein A-I (Apo-A1) is the main protein in the HDL cholesterol’s (good cholesterol) structure. Its primary function is to protect and transport the HDL particles through the bloodstream. An Apo-A1 test is mainly used to help assess your risk of developing cardiovascular disease (CVD).
Apolipoprotein A-I Test
Also called: Apo A-I, Apolipoprotein A1, Apo-A1
Apolipoprotein A-I (Apo-A1) is the main protein in the HDL cholesterol’s (good cholesterol) structure. Its primary function is to protect and transport the HDL particles through the bloodstream. An Apo-A1 test is mainly used to help assess your risk of developing cardiovascular disease (CVD).
{"label":"Apolipoprotein A-I Reference Range","scale":"lin","step":0.1,"hideunits":false,"units":[{"printSymbol":"mg\/dL","code":"mg\/dL","name":"milligram per deciliter"}],"items":[{"flag":"abnormal","label":{"short":"Low","long":"Low","orientation":"horizontal"},"values":{"min":0,"max":80},"text":"Low APO-A1 levels indicate that you have a higher risk of atherosclerosis-based heart disease.","conditions":["Cardiovascular disease","Tangier disease","Smoking","Obesity","Uncontrolled diabetes","Chronic kidney disease","Intake of certain drugs"]},{"flag":"normal","label":{"short":"Normal","long":"Normal","orientation":"horizontal"},"values":{"min":80,"max":151},"text":"Normal results can vary based on the laboratory and the method used.","conditions":[]},{"flag":"abnormal","label":{"short":"High","long":"High","orientation":"horizontal"},"values":{"min":151,"max":300},"text":"High APO-A1 levels indicate that you have a decreased risk of atherosclerosis-based heart disease.","conditions":["Pregnancy","Weight reduction","Use of statins","Physical exercise","Intake of certain drugs"]}],"value":115.5}[{"abnormal":0},{"normal":0},{"abnormal":0}]
Use the slider below to see how your results affect your
health.
mg/dL
80
151
Your result is Normal.
Normal results can vary based on the laboratory and the method used.
Related conditions
Apolipoproteins are certain types of proteins that play specific roles in the metabolism and transportation of lipids (fat) through the bloodstream.
Apolipoprotein A1 (Apo-A1) is a human protein that is an important component of HDL cholesterol (known as “good” cholesterol”). It takes care of HDL cholesterol particle’s transportation, protection, and structure maintenance.
An Apo-A1 test measures the levels of apolipoprotein A1 in a sample of your blood.
An Apo-A1 test is mostly used to help determine your risk of developing cardiovascular disease (CVD). Less often, it can also be ordered to detect genetical disorder called Tangier disease.
Apo-A1 test is not routinely ordered as this test is not meant to replace other biomarkers to assess heart disease but it provides a more accurate overview of your health condition. Apo-A1 can be indicated in the following cases:
When the level of cholesterol or triglycerides in your blood is high
In case of existing family history of atherosclerosis/heart diseases
To assess your risk of developing heart disease
To monitor the levels of Apo-A1 after changes in your lifestyle or during lipid treatment
A needle will be used to take a blood sample from a vein in your arm.
You may be asked to fast for about 12 hours before the test in case of other lipid tests (cholesterol, triglycerides) are ordered.
You may feel discomfort when the needle is inserted and extracted but otherwise is a quick procedure. You may also experience bruising and a little bleeding, as well as mild soreness for a short amount of time after the blood extraction.
Normal reference ranges are from 80 to 151 mg/dL.
Causes of decreased Apo-A1 levels:
Low Apo-A1 results indicate a higher risk for atherosclerosis-based heart disease. Critically low (<25 mg/dL) Apo-A1 levels might indicate a genetic disorder such as Tangier disease. Other causes include:
Smoking
Obesity
Uncontrolled diabetes
Chronic kidney disease
Intake of certain drugs, including synthetic progesterone, diuretics, androgens, and beta blockers, among others.
Causes of increased Apo-A1 levels:
Pregnancy
Weight reduction
Use of statins
Physical exercise
Intake of certain drugs, including oral contraceptives, estrogen, ethanol, and carbamazepine, among others.
There is a tendency for women to have higher levels of Apo-A1 in their blood. This is caused by their naturally higher levels of HDL.
Decreasing the amounts of saturated fat intake through your diet, along with regular exercise, can help you increase your HDL and APO-A1 levels.
Lab Tests Online. Apo A-I. [accessed on Mar 22, 2018]
Mayo Medical Laboratories. Test ID: APLA1. [accessed on Mar 22, 2018]
GeneCards. Apo A1 Gene. [accessed on Mar 22, 2018]
Fontanarosa, P., & Christiansen, S. (2009, April 01). Laboratory Values. AMA Manual of Style. Ed. [accessed on Oct 09, 2018]
Normal reference ranges can vary depending on the laboratory and the method used for testing. You must use the range supplied by the laboratory that performed your test to evaluate whether your results are "within normal limits."
Additional Materials (2)
Lipid Panel Interpretation
Video by FatIsNotYourFault/YouTube
Lipoproteins
Lipoproteins are protein spheres that transport lipids through your bloodstream.
Image by TheVisualMD
1:16:38
Lipid Panel Interpretation
FatIsNotYourFault/YouTube
Lipoproteins
TheVisualMD
APOE ε4 Test
APOE ε4 Test
Also called: APOE Alzheimer's Risk, Apolipoprotein E4, ApoE4
Apolipoprotein E (APOE) gene is a gene on chromosome 19 involved in making a protein that helps carry cholesterol and other types of fat in the bloodstream. The APOE gene has three common alleles: ε2, ε3, and ε4. The APOE ε4 allele is the major known risk-factor gene for late-onset Alzheimer's disease.
APOE ε4 Test
Also called: APOE Alzheimer's Risk, Apolipoprotein E4, ApoE4
Apolipoprotein E (APOE) gene is a gene on chromosome 19 involved in making a protein that helps carry cholesterol and other types of fat in the bloodstream. The APOE gene has three common alleles: ε2, ε3, and ε4. The APOE ε4 allele is the major known risk-factor gene for late-onset Alzheimer's disease.
{"label":"APOE \u03b54 Reference Range","scale":"lin","step":0.25,"hideunits":true,"items":[{"flag":"negative","label":{"short":"Negative","long":"Negative","orientation":"horizontal"},"values":{"min":0,"max":1},"text":"A negative result indicates that you don\u2019t have the APOE \u03b54 allele. However, this does not ensure that you won\u2019t develop Alzheimer\u2019s disease in the future. ","conditions":[]},{"flag":"borderline","label":{"short":"Heterozygous","long":"Heterozygous","orientation":"horizontal"},"values":{"min":1,"max":2},"text":"If you're heterozygous for APOE \u03b54, meaning having one APOE \u03b54 allele, your risk of developing late-onset AD is approximately two to three times greater than it is for people who don\u2019t have the allele. ","conditions":["Alzheimer's disease","Dementia","Atherosclerosis"]},{"flag":"positive","label":{"short":"Homozygous","long":"Homozygous","orientation":"horizontal"},"values":{"min":2,"max":3},"text":"If you're homozygous for APOE \u03b54, meaning having two APOE \u03b54 allele, your risk of developing late-onset AD is approximately ten to fifteen times greater than it is for people who don\u2019t have the allele.","conditions":["Alzheimer's disease","Dementia","Atherosclerosis"]}],"value":0.5}[{"negative":0},{"borderline":0},{"positive":0}]
Use the slider below to see how your results affect your
health.
Your result is Negative.
A negative result indicates that you don’t have the APOE ε4 allele. However, this does not ensure that you won’t develop Alzheimer’s disease in the future.
Related conditions
The APOE gene, located on chromosome 19, provides instructions for making a protein called apolipoprotein E. This protein combines with fats (lipids) in the body to form molecules called lipoproteins. Lipoproteins are responsible for packaging cholesterol and other fats and carrying them through the bloodstream.
There are at least three slightly different versions (alleles or variants) of the APOE gene. The major alleles are called ε2, ε3, and ε4.
APOE ε4 is associated with an increased risk for Alzheimer’s disease (AD), particularly of late-onset (AD that develops after the age of 65). A person has zero, one, or two APOE ε4 alleles. Having more APOE ε4 alleles increases the risk of developing Alzheimer's. The APOE ε4 allele may also be associated with an earlier onset of memory loss and other symptoms. However, APOE ε4 alone is neither sufficient nor necessary for the development of the disease.
This test evaluates a person's DNA to detect the presence of the APOE ε4 variant.
The APOE ε4 test is not widely performed, and the usefulness of this test is still being researched.
Your doctor may want to order an APOE ε4 test in conjunction with other exams when you have progressive symptoms of dementia that could be attributed to Alzheimer’s disease.
Alzheimer’s disease is an irreversible form of dementia that is not a normal part of the aging process.
This disease is characterized by personality and behavioral changes, a gradual decline in intellectual ability, memory loss, and deteriorating language and speech skills, that eventually interfere with daily living.
There are 2 types of Alzheimer’s disease, which are early-onset (EOAD) and late-onset (LOAD).
EOAD is rare and occurs in people of 30 to 60 years of age. Even though some cases of early-onset disease have no known cause, most cases are inherited (transmitted from parent to child).
LOAD is the most common form, occurs in people of 60-65 years of age, and it is believed to appear due to a combination of genetic, environmental, and lifestyle factors.
A small amount of blood will be drawn from a vein in your arm by using a needle, or cells from your mouth will be collected by doing an oral rinse.
If your test is done by collecting a blood sample, no fasting or other preparations are needed.
If your test is done by taking a sample of your saliva, you should refrain from eating or drinking for at least one hour before the test is done. Kissing should also be avoided before the sample is taken.
If your test is done by collecting a blood sample, you may feel a little sting when the needle is inserted and extracted but otherwise is a quick procedure. You may also experience bruising and a little bleeding, as well as mild soreness for a short amount of time after the extraction.
There are no risks when the sample is collected via oral rinse.
APOE ε4 is called a risk-factor gene because it increases a person's risk of developing the disease. However, inheriting an APOE ε4 allele does not mean that a person will definitely develop Alzheimer's. Some people with an APOE ε4 allele never get the disease, and others who develop Alzheimer's do not have any APOE ε4 alleles.
Negative (no ε4 alleles detected)
A negative result indicates that you don’t have the APOE ε4 allele.
Positive (one or two ε4 alleles present)
A positive result indicates that you have at least one APOE ε4 allele, which means that you have an increased risk of developing Alzheimer’s disease.
The APOE ε4 allele can be inherited either from one parent (which means that the child will have only one copy of the allele) or from both parents (in this case the child will have two alleles, one from each parent).
Therefore, if you have:
One copy of the allele (heterozygous): your risk of developing late-onset AD is approximately two to three times greater than it is for people who don’t have the allele.
Two copies of the allele (homozygous): your risk of developing late-onset AD is approximately ten to fifteen times greater than it is for people who don’t have the allele.
The development of Alzheimer’s disease is influenced by many factors other than APOE ε4, including family history, gender, age, level of education, and history of head trauma.
Variants of apolipoprotein E have been studied extensively as risk factors for many different conditions. For example, APOE alleles have been shown to influence the risk of cardiovascular diseases. People who carry at least one copy of the APOE ε4 allele have an increased chance of developing atherosclerosis, which is an accumulation of fatty deposits and scar-like tissue in the lining of the arteries. This progressive narrowing of the arteries increases the risk of heart attack and stroke.
NIH National Institute on Aging. Alzheimer's Disease Genetics Fact Sheet. [accessed on Sep 20, 2018]
NIH Genetics Home Reference. APOE gene. [accessed on Sep 20, 2018]
American College of Medical Genetics, Bethesda, MD. Statement on Use of Apolipoportein E Testing for Alzheimer Disease. [accessed on Sep 20, 2018]
LabCorp Test Menu. 504040: APOE Alzheimer's Risk. [accessed on Sep 20, 2018]
Mayo Medical Laboratories. Test ID: APOEG. Apolipoprotein E Genotyping, Blood. [accessed on Sep 20, 2018]
Medscape. Alzheimer Disease and APOE-4: Overview, Clinical Implications. Author: Shivani Garg, MD, MBBS; Chief Editor: Karl S Roth, MD. [accessed on Sep 20, 2018]
Huynh, R. A., & Mohan, C. (2017). Alzheimer’s Disease: Biomarkers in the Genome, Blood, and Cerebrospinal Fluid. Frontiers in Neurology, 8, 102. http://doi.org/10.3389/fneur.2017.00102 [accessed on Sep 20, 2018]
Stocker, H., Möllers, T., Perna, L., & Brenner, H. (2018). The genetic risk of Alzheimer’s disease beyond APOE ε4: systematic review of Alzheimer’s genetic risk scores. Translational Psychiatry, 8, 166. http://doi.org/10.1038/s41398-018-0221-8 [accessed on Sep 20, 2018]
Alzheimer's Drug Discovery Foundation. Cognitive Vitality. What APOE Means for Your Health. Penny Dacks, PhD. [accessed on Sep 20, 2018]
Mayo Clinic. Alzheimer's: Is it in your genes? [accessed on Sep 20, 2018]
ApoE4.Info. APOE-ε4 Introduction. [accessed on Sep 20, 2018]
Normal reference ranges can vary depending on the laboratory and the method used for testing. You must use the range supplied by the laboratory that performed your test to evaluate whether your results are "within normal limits."
Additional Materials (23)
Ideogram of human chromosome 19
Selected genes, traits, and disorders associated with the chromosome listed; (blue and violet) regions reflecting the unique patterns of light and dark bands seen on human chromosomes stained to allow viewing through a light microscope; (red) the centromere, or constricted portion, of each chromosome; (yellow) chromosomal regions that vary in staining intensity and sometimes are called hererochromatin (meaning “different color”); (lines between yellow) variable regions, called stalks, that connect a very small chromosome arm (a “satellite”) to the chromosome.
Image by Office of Biological and Environmental Research of the U.S. Department of Energy Office of Science, the Biological and Environmental Research Information System, Oak Ridge National Laboratory.
How APOE4 Contributes to Alzheimer’s Risk
Video by Cell Press/YouTube
Apolipoprotein A-I
Apolipoprotein A-I is a protein that in humans is encoded by the APOA1 gene. It has a specific role in lipid metabolism. Recent report suggest that APOA1 mRNA is regulated by endogenously expressed antisense RNA. Apolipoprotein A-I is the major protein component of high density lipoprotein (HDL) in plasma.
Image by TheVisualMD
Anatomy of a Lipoprotein
Lipoproteins transport cholesterol, triglycerides, or other lipids through the bloodstream. Lipoproteins are protein spheres that consist of a core of triglycerides and cholesterol esters, surrounded by a shell made up of water-soluble phospholipids with embedded proteins and cholesterol. The lipid-laden core of the lipoprotein is insoluble in aqueous (water-based) blood, so the phospholipid-protein shell is necessary to allow the lipoprotein to float freely in the bloodstream.
Image by TheVisualMD
Anatomy of a Lipoprotein
Lipoproteins transport cholesterol, triglycerides, or other lipids through the bloodstream. Lipoproteins are protein spheres that consist of a core of triglycerides and cholesterol esters, surrounded by a shell made up of water-soluble phospholipids with embedded proteins and cholesterol. The lipid-laden core of the lipoprotein is insoluble in aqueous (water-based) blood, so the phospholipid-protein shell is necessary to allow the lipoprotein to float freely in the bloodstream.
Image by TheVisualMD
Anatomy of a Lipoprotein
Lipoproteins transport cholesterol, triglycerides, or other lipids through the bloodstream. Lipoproteins are protein spheres that consist of a core of triglycerides and cholesterol esters, surrounded by a shell made up of water-soluble phospholipids with embedded proteins and cholesterol. The lipid-laden core of the lipoprotein is insoluble in aqueous (water-based) blood, so the phospholipid-protein shell is necessary to allow the lipoprotein to float freely in the bloodstream.
Image by TheVisualMD
Anatomy of a Lipoprotein
Lipoproteins transport cholesterol, triglycerides, or other lipids through the bloodstream. Lipoproteins are protein spheres that consist of a core of triglycerides and cholesterol esters, surrounded by a shell made up of water-soluble phospholipids with embedded proteins and cholesterol. The lipid-laden core of the lipoprotein is insoluble in aqueous (water-based) blood, so the phospholipid-protein shell is necessary to allow the lipoprotein to float freely in the bloodstream.
Image by TheVisualMD
Entorhinal Cortex in Alzheimer's disease
Entorhinal cortex (red) was thinnest in youth with Alzheimer's-related ApoE4 gene variant. View of left entorhinal cortex from beneath the brain, with front of brain at top. Artist's rendering.
Image by Source: Philip Shaw, M.D., NIMH Child Psychiatry Branch
Aging vs Alzheimer's Disease
Research shows that a brain affected by Alzheimer’s disease looks very different from one undergoing normal aging. While all brains shrink in volume as we get older, Alzheimer’s brains lose even more volume than healthy brains. Understanding these differences could lead to better ways to diagnose the disease earlier, even before symptoms appear. Hippocampus Recent imaging studies show that Alzheimer’s can lead to a 10% shrinkage in the hippocampus over two years, compared to a 4% reduction in volume among healthy people. The disease can also cause changes in the shape of this region, due to the intrusion of abnormal proteins that are linked to Alzheimer’s. Cerebral Cortex There are about 1010th nerve cells in this part of the brain, which makes up the outer covering of the brain. The cortex is critical for intelligence, personality, planning and motor functions. In Alzheimer’s disease the cortex shrinks because of the loss of nerve cells. Ventricles Our brains have four large cavities, each filled with fluid that flows between the brain and the spinal cord. Because Alzheimer’s causes nerve cells to die, Alzheimer’s patients tend to have larger ventricles since more of their brain tissue is destroyed. Basal Ganglia This grouping of nerve cells located on each side of the brain’s hemispheres is critical to coordinating cognition and voluntary movement; in Alzheimer’s patients, their activity on both sides of the brain is no longer even, resulting in difficulty organizing thoughts and movements. White Matter Tracts Nerve cell tissue is divided into two types—white and grey matter. White matter makes up the bulk of nerve cell volume, and includes the axons and their protective layer, known as myelin. Alzheimer’s patients show signs of reduced white matter in relation to grey matter, particularly in regions important to memory, which suggests that as the disease progresses, nerve cells are losing their axonal links to one another. How Different is the Alzheimer’s Brain? By the time Alzheimer’s is well-established, there are distinct differences between an affected brain and one that is aging normally, say experts. But increasingly, they believe it’s important to identify those who are in the early stages of disease, so they might benefit from lifestyle interventions, such as keeping their brains active, that might slow down the progression of Alzheimer’s. But is it possible to select out these patients before their symptoms give them away? That’s still an open question, but with advances in imaging techniques that can get ever finer resolution of brain structures, researchers are hopeful they can pick out the first signs of Alzheimer’s—or at least the first signs of abnormal aging—so they can study these patients further. They are also working on protein tests, hopefully based on blood, that can detect proteins specific to the disease, even in its earliest stages.
Image by TheVisualMD
A Healthier Outlook
Get Active While nothing has been proven to stop Alzheimer's, studies show that some behaviors may help to lessen the symptoms of cognitive decline and memory loss. There are some lifestyle habits that could theoretically help prevent Alzheimer’s. Staying physically active can keep blood flowing to the brain to nourish nerve cells so they can function. Many caregivers help patients to maintain a regular schedule of walking or other exercise to keep them active.
Stay Socially Engaged Being part of a strong network of family and friends may keep the brain stimulated and help to maintain nerve cell networks involved in memory. Church groups and other regular social gatherings are also a good way to strengthen social ties.
Train Your Brain Any activity that engages the brain's powers to think, organize and plan can strengthen the nerve circuits that keep the intellect sharp. Games and puzzles, as well as learning new things such as languages, may work to reinforce nerve cell networks that are vulnerable to decline in Alzheimer's.
Eat Healthy There is no anti-Alzheimer's diet, but a heart-healthy eating strategy can help to maintain blood flow to the brain to nourish nerve cells.
Rest your brain Sleep is a critical part of the brain's daily work cycle. Because events during the day are replayed and stored during sleep as memories, getting enough rest may help even a brain affected by Alzheimer's to maintain as much recall as possible.
The Nun Study, a long-term investigation of the lifestyle factors that contribute to aging, provides some of the strongest evidence of the power of brain training to combat Alzheimer’s. And that training includes education. In the ongoing study, researchers perform autopsies of brains donated by sisters of the School Sisters of Notre Dame. What makes the sisters ideal participants in the study are detailed records kept by the Order that detail their education, life experiences and even their writing samples. When the scientists compared writing samples the nuns had written before taking their vows in which they described themselves, for example, they learned that the nuns who used more expressive and complicated sentence structure were less likely to succumb to Alzheimer’s than those who used more simple constructions. The sisters are already putting into practice what scientists are learning about lowering the risk of Alzheimer’s; they regularly play thinking games and spend time knitting and writing. The Nun Study continues to identify such modifiable lifestyle factors that may help to control or reverse the disease.
Image by TheVisualMD
This browser does not support the video element.
What Is Alzheimer's Disease?
Creating memories is one of the brain's most remarkable functions.The hippocampus, located deep inside the brain, serves as the hub for making and storing memories. Located in front of the hippocampus is the amygdala, your emotional nexus. The entorhinal cortex acts as a gateway between the hippocampus and the rest of the cerebral cortex.The nerve cell is the hub for all of the activity that occurs in the brain, and the connections between nerve cells create a living, dynamic framework for everything that we see, hear, taste, smell, touch and experience. In Alzheimer's disease, beta amyloid proteins accumulate to form large plaques between nerve cells. Eventually, the amyloid deposits block off the nerve cells from their network and cause the cells to die.Alzheimer's is not thought to be caused by amyloid alone. Experts say that the amyloid buildup has an accomplice in another compound that interferes with nerve cell function, neurofibrillary tangles.
Video by TheVisualMD
Alzheimer's Culprit- Dangers Outside the Cell
Amyloid beta protein that is made by cells during normal metabolism. But in some people, too much of this protein remains in the brain, where it binds to dendrites on nerve cells and interferes with their normal function. These beta amyloid proteins accumulate to form large plaques between nerve cells. Eventually, the amyloid deposits block off the nerve cells from their network and cause the cells to die. Researchers believe that amyloid is the key to Alzheimer’s disease, and the latest research suggests that it’s not that people with Alzheimer’s make too much amyloid; rather, they aren’t able to clear the protein from the brain properly. While it’s clear that amyloid plays a role in the Alzheimer’s process, what is less obvious is whether removing the protein can treat the disease. Why? The disease occurs gradually over a long period of time, and the interventions might have simply been used too late. Researchers are currently studying whether these types of treatments might be more effective if introduced earlier in the disease process. Challenge: Why can’t doctors test for amyloid to diagnose Alzheimer’s in the living brain? Solution: There are ways to measure amyloid in the brain, from imaging studies that physically detect deposits to molecular tests that measure the protein in spinal fluid. But there are no threshold values for what normal levels of amyloid are, and what levels are associated with Alzheimer’s. Autopsies have shown that many people without outward symptoms of Alzheimer’s, for example, have elevated amounts of amyloid in their brain.
Image by TheVisualMD
Diagnosing Alzheimer's Disease
In Alzheimer's disease, certain proteins are deposited in the brain, including beta amyloid protein and tau. The buildup of these two proteins leads to nerve injury and the symptoms of Alzheimer's dementia.
Image by TheVisualMD
Stages of Alzheimer
1. Preclinical AD: These individuals have evidence of pathological changes that are Alzheimer's specific. During this stage, no symptoms or major structural changes to the brain are noticeable.
2. Mild cognitive impairment (MCI) due to AD: Individuals may experience memory loss or problems with organizing and planning, but the deficits aren't serious enough to interfere with their daily lives.
3. Alzheimer's dementia: Differs from MCI in that cognitive symptoms significantly interfere with daily lives. The patient also shows cognitive deficits in memory, language, visual recognition, and executive function.
4.Alzheimer's dementia
Image by TheVisualMD
Early Detection - Emerging Concepts in Diagnosis
Researchers can detect one form of amyloid beta protein (A-beta 42) in the cerebrospinal fluid (CSF), the fluid that surrounds the brain and spinal cord. As Alzheimer’s disease progresses, A-beta 42 decreases, but it is not understood why. It’s also not clear how much amyloid is too much when it comes to causing Alzheimer’s. Some autopsies of elderly brains show considerable amounts of amyloid deposits even when that person showed no signs of cognitive decline or other symptoms of Alzheimer’s when they were alive.
Image by TheVisualMD
Alzheimer's disease
Alzheimer's disease (AD): Combination of two brain diagrams in one for comparison. In the left normal brain, in the right brain of a person with Alzheimer's disease
Image by Alzheimer's Disease Education and Referral Center, a service of the National Institute on Aging
Healthy versus Alzheimer's Brain 4b
With the progression of Alzheimer's significant changes can be seen in the brain.
Image by TheVisualMD
Healthy versus Alzheimer's Brain 3a
With the progression of Alzheimer's significant changes can be seen in the brain.
Image by TheVisualMD
Healthy versus Alzheimer's Brain 3b
With the progression of Alzheimer's significant changes can be seen in the brain.
Image by TheVisualMD
cerebral blood vessels neurons and plaques
cerebral blood vessels neurons and plaques
Image by TheVisualMD
Chylomicron
Chylomicron structure - ApoA, ApoB, ApoC, ApoE (apolipoproteins); T (triacylglycerol); C (cholesterol); green (phospholipids)
Image by Xvazquez
Chylomicron Lipoprotein
This image shows a whole globule of chylomicron, a lipoprotein found in the blood and lymphatic fluid. Chylomicrons transport triglycerides and other fats from the intestine to the liver and adipose (fatty) tissue. They are composed mostly of fat with a small amount of protein, making them the least dense of the lipoproteins. The outer layer contains the fat like substance phospholipid (8%). Inside, the globule contains 87% triglycerides and 1% protein.
Image by TheVisualMD
Chylomicron Lipoprotein Cross-Section
A Chylomicron is a small fat globule composed of protein and fat. Chylomicrons are found in the blood and lymphatic fluid where they serve to transport fat from its port of entry in the intestine to the liver and to adipose tissue. There is a cross-section through the phospholipid layer, exposing the triglyceride core beneath. It is the least dense, with 8% phospholipid (off-white outer layer), 87% triglyceride (red), 1% protein (purple)
Image by TheVisualMD
Ideogram of human chromosome 19
Office of Biological and Environmental Research of the U.S. Department of Energy Office of Science, the Biological and Environmental Research Information System, Oak Ridge National Laboratory.
4:32
How APOE4 Contributes to Alzheimer’s Risk
Cell Press/YouTube
Apolipoprotein A-I
TheVisualMD
Anatomy of a Lipoprotein
TheVisualMD
Anatomy of a Lipoprotein
TheVisualMD
Anatomy of a Lipoprotein
TheVisualMD
Anatomy of a Lipoprotein
TheVisualMD
Entorhinal Cortex in Alzheimer's disease
Source: Philip Shaw, M.D., NIMH Child Psychiatry Branch
Aging vs Alzheimer's Disease
TheVisualMD
A Healthier Outlook
TheVisualMD
5:18
What Is Alzheimer's Disease?
TheVisualMD
Alzheimer's Culprit- Dangers Outside the Cell
TheVisualMD
Diagnosing Alzheimer's Disease
TheVisualMD
Stages of Alzheimer
TheVisualMD
Early Detection - Emerging Concepts in Diagnosis
TheVisualMD
Alzheimer's disease
Alzheimer's Disease Education and Referral Center, a service of the National Institute on Aging